The document describes the structure and function of blood vessels in the arterial, venous, and capillary systems. The arterial system includes elastic arteries that dampen blood pressure changes and deliver smooth blood flow, muscular arteries that distribute blood to organs, and arterioles that regulate blood flow into capillaries. The venous system contains venules that form into thin-walled veins with valves to prevent backflow, and capacitance veins that act as reservoirs with low pressure allowing thin walls. Capillaries are the smallest blood vessels where gas exchange occurs, and come in continuous, fenestrated, and sinusoidal types that permit different levels of permeability.
The Human Blood Circulatory system
Humans and other vertebrates have a closed blood circulatory system:
This system consists of
the heart (pump),
series of blood vessels
the blood that flows through them.
This means that circulating blood is pumped through a system of vessels.
Functions of Human Blood Circulatory System
1. oxygen
2. carbon dioxide
3 nutrients
4. water
5. ions
6. hormones
7. antibodies
8. metabolic wastes
The Human Blood Circulatory system
Humans and other vertebrates have a closed blood circulatory system:
This system consists of
the heart (pump),
series of blood vessels
the blood that flows through them.
This means that circulating blood is pumped through a system of vessels.
Functions of Human Blood Circulatory System
1. oxygen
2. carbon dioxide
3 nutrients
4. water
5. ions
6. hormones
7. antibodies
8. metabolic wastes
Blood vessels: Arteries, Veins and CapillariesAmir Rifaat
It is one of the circulatory systems. This explains the roles of arteries, veins and capillaries. It also differentiate between the arteries, veins and capillaries. This slide also explained the pulmonary circuit and systemic curcuit. This is an interesting notes and easy to be understand.
The muscle are biological motors which convert chemical energy into force and mechanical work.
This biological machinery is composed of proteins – which is actomyosin and the fuel is ATP.
With the use of muscles we are able to act on our environment.
Blood Vessels
By: Saiyed Falakaara
Assistant Professor
Department of Pharmacy
Sumandeep Vidyapeeth
Introduction
Blood vessels form a closed system of tubes that carry blood away from the heart, transport it to the tissues of the body, and then return it to the heart.
The blood vessels of human body carry blood to every tissue and organ.
Vessels decrease in size as they move away from the heart (arteries and arterioles), ending in the capillaries, and then increase in size as they move towards the heart (venules and veins)
The largest artery in the blood is Aorta.
Types of blood vessels
1. Arteries
2. Arterioles
3. Capillaries
4. Venules
5. veins
The first topic in the practical histology coarse for pharmacy students
In this lecture the student will be able to recognize the histological layers of the circulatory system parts such as veins and arteries and the similarities and differences between each layer
There are three kinds of blood vessels: arteries, veins, and capillaries.
Each of these plays a very specific role in the circulation process/blood circulation.
Arteries transport blood away from the heart.
Veins return blood back toward the heart.
Capillaries surround body cells and tissues to deliver and absorb oxygen, nutrients, and other substances.
The capillaries also connect the branches of arteries and to the branches of veins.
The walls of most blood vessels have three distinct layers: the tunica externa, the tunica media, and the tunica intima.
Learning Objectives:
Compare and contrast the structure and function
of
Arteries
Veins
Capillaries
ulatory
system
Arteries
Arterioles
Capillaries
Venules
Veins
3 tunics
Lume
The Vessels
Functions:
Distribution of blood
Exchange of materials with tissues
Return of blood to the heart
Structure:
Most have the same basic structure:
– 3 layers surrounding a hollow lumen
What is the endothelium part of the tunica externa in arteries amp.pdfarshicollection001
What is the endothelium? part of the tunica externa in arteries ample squamous epithelium that
is in contact with the blood the internal elastic membrane that has fenestrae concentric \"holey\"
(laminae) of elastic connective tissue interspersed between smooth muscle layers of the tunica
media Blood vessels of the large arteries and veins that are greater than 1mm in diameter are
called the lamina propria anastomoses fenestrae metarterioles vasavasorum sinusoids Select
all of the following that are TRUE of muscular arteries. largest diameter arteries subclavian
artery is an example the tunica media has more smooth muscle than elastic fibers they are also
referred to as distributing arteries they contain both the internal elastic membrane and the
external elastic membrane proportionately, has the thickest tunica media of ail vessels common
iliac artery is an example Find the correct statement regarding our capillaries. capillaries that
have tight junctions between endothelial cells, making them less permeable to large molecules
than other capillary types are referred to as sinusoidal capillaries or discontinuous capillaries
continuous capillaries are found in the endocrine glands where large molecules cross the
capillary walls fenestrated capillaries are the most common type of capillaries the distal portion
of the metarteriole that has no smooth muscle is called a thoroughfare channel Select all of the
TRUE statements regarding our blood vessels. arterioles can be called our \"resistance vessels\"
because this is where blood encounters its creates! decline in blood pressure b a venous
anastomosis is where two or more veins dram an area in common there are about 10 billion
capillaries. yet only about 5% of our blood is in them at any one time venules have only the
tunica internal and the tunica external, they have NO tunica media about 40% of the blood is in
veins at any given time capillaries are known as blood reservoirs for extra blood veins of the
appendages that are greater than 2 mm in diameter have valves made of fold in the intima and are
similar to shape and function of the semilunar valves compared to their companion arteries,
veins have a very thick tunica intima which contains an internal elastic membrane, a thin tunica
mod a with no external elastic membrane and a vety tunica adventitia (externa)
Solution
1. Endothelium is:
b. simple squamous cells that is in contact with the blood
2. Vasa vasorum
3. Tunica media has more smooth muscles than elastic fibers
They are also called distributing artery
4. The distal portion of the metarteriole that has no smooth muscle is called a thoroughfare
channel.
Presentación sobre enfermedades diarreicas agudas, enfocada a explicar las principales medidas preventivas según las guías de práctica clínica de la Secretaría de Salud Mexicana y las recomendaciones de la NOM-031-SSA
Definición, Epidemiología, Diagnóstico, Tratamiento y Prevención de las Enfermedades Respiratorias Agudas. Enfocado en medicina preventiva del niño menor de 5 años. Basada en las guías de práctica clínica del Instituto Mexicano del Seguro Social y otras fuentes.
Revisión bibliográfica del síndrome de distrés respiratorio agudo para la clase de neumología. Epidemiología, fisiopatología, cuadro clínico, diagnóstico y tratamiento. (2015)
Presentacion sobre las principales características sobre la fisiopatología, manifestaciones clinicas, diagnostico, tratamiento y complicaciones de la otitis externa
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
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5. Arterialsystem Classification based on size and function
1. Elastic (conducting) arteries
a. Characteristics
i. Thick-walled
ii. Near heart
iii. Largest diameter
iv. More elastic
v. Large lumen
b. Properties
i. Dampen BP changes associated with heart contraction
ii. Passive accommodation results in smooth flow of blood
c. 1.0 - 2.5 cm
2. Muscular arteries-distributing arteries
a. Distal to elastic arteries
b. Deliver blood to specific organs
c. Thick media layer
i. More smooth muscle
d. 0.3 - 1.0 cm
3. Arterioles
a. Determine flow into capillary beds
b. Mostly smooth muscle
c. 10 µm - 0.3 cm
6.
7. Venoussystem A. Types of vessels
1. Venules
a. 8 - 100 µm
b. Characteristics vary with size
i. Little muscle
ii. Thin externa
2. Veins
a. Formed from venules
b. Thinner walls and less muscle than arteries
c. Little muscle in media
i. Mostly elastin
d. Externa is thickest wall layer
B. Capacitance vessels
1. Veins act as reservoirs
a. Large lumens
b. Low blood pressure allows walls to thin
2. Venous valves
a. Prevent backflow
b. Folds of interna
8.
9.
10. Capillaries
Smallest blood vessels 8 - 10 µm one cell thick
Exchange of materials
Very low blood pressure
Where gas exchange takes place.
They can carry oxygenated and deoxygenated blood
11. Types of capillaryContinuous
• Uninterrupted
endothelial
cells
• Incomplete
tight junctions
• Intercellular
clefts
Fenestrated
• Endothelial
cells have oval
pores
(Fenestrations)
• Pores permit
greater
permeability
Sinusoidal
• Modified,
leaky
capillaries
• Large
molecules can
pass through
There are three types of arteries in the body: elastic arteries, muscular arteries, and arterioles.
Arteries that leave the heart to distribute the oxygenated blood exhibit progressive branching.
With each branching, the luminal diameters of the arteries gradually decrease, until the smallest
vessel, the capillary, is formed.
Elastic arteries are the largest blood vessels in the body and include the pulmonary trunk
and aorta with their major branches. The walls of these vessels are primarily composed of elastic
connective tissue fibers. These fibers provide great resilience and flexibility during blood flow.
The large elastic arteries branch and become medium-sized muscular arteries, the most
numerous vessels in the body. In contrast to the walls of elastic arteries, those of muscular
arteries contain greater amounts of smooth muscle fibers. Arterioles are the smallest branches
of the arterial system. Their walls consist of one to five layers of smooth muscle fibers. Arterioles
deliver blood to the smallest blood vessels, the capillaries.
Capillaries unite to form larger blood vessels called venules; venules usually accompany arterioles.
The venous blood initially flows into smaller postcapillary venules and then into veins of
increasing size. The veins are arbitrarily classified as small, medium, and large. Compared with
arteries, veins typically are more numerous and have thinner walls, larger diameters, and greater
structural variation.
Small-sized and medium-sized veins, particularly in the extremities, have valves. Because of
the low blood pressure in the veins, blood flow to the heart in the veins is slow and can even back
up. The presence of valves in veins assists venous blood flow by preventing backflow.When blood
flows toward the heart, pressure in the veins forces the valves to open. As the blood begins to flow
backward, the valve flaps close the lumen and prevent backflow of blood. Venous blood between
the valves in the extremities flows toward the heart as a result of contraction of muscles that surround
the veins.Valves are absent in veins of the central nervous system, the inferior and superior
venae cavae, and viscera.
The walls of the veins, like the arteries, also exhibit three layers or tunics. However, the muscular
layer is much less prominent. The tunica intima in large veins exhibits a prominent endothelium
and subendothelial connective tissue. In large veins, the muscular tunica media is thin, and
the smooth muscles intermix with connective tissue fibers. In large veins, the tunica adventitia is
the thickest and best-developed layer of the three tunics. Longitudinal bundles of smooth muscle
fibers are common in the connective tissue of this layer
The wall of a typical artery contains three concentric layers or tunics.
The innermost layer is the tunica intima. This layer consists of a simple squamous epithelium, called endothelium in the vascular system, and the underlying subendothelial connective tissue.
The middle layer is the tunica media, composed primarily of smooth muscle fibers.
The outermost layer is the tunica adventitia, composed primarily of collagen and elastic connective tissue fibers.
The walls of some muscular arteries also exhibit two thin, wavy bands of elastic fibers. The internal elastic lamina is located between the tunica intima and the tunica media; this layer is not seen in smaller arteries. The external elastic lamina is located on the periphery of the muscular tunica media and is primarily seen in large muscular arteries.
Capillaries are the smallest blood vessels. Their average diameter is about 8 μm, which is about
the size of an erythrocyte (red blood cell). There are three types of capillaries: continuous capillaries,
fenestrated capillaries, and sinusoids. These structural variations in capillaries allow for different
types of metabolic exchange between blood and the surrounding tissues.
Continuous capillaries are the most common. They are found in muscle, connective tissue,
nervous tissue, skin, respiratory organs, and exocrine glands. In these capillaries, the endothelial
cells are joined and form an uninterrupted, solid endothelial lining.
Fenestrated capillaries are characterized by large openings or fenestrations (pores) in the
cytoplasm of endothelial cells designed for a rapid exchange of molecules between blood and tissues.
Fenestrated capillaries are found in endocrine tissues and glands, small intestine, and kidney
glomeruli.
Sinusoidal (discontinuous) capillaries are blood vessels that exhibit irregular, tortuous
paths. Their much wider diameters slow down the flow of blood. Endothelial cell junctions are
rare in sinusoidal capillaries, and wide gaps exist between individual endothelial cells. Also,
because a basement membrane underlying the endothelium is either incomplete or absent, a
direct exchange of molecules occurs between blood contents and cells. Sinusoidal capillaries are
found in the liver, spleen, and bone marrow.
Capillaries do not function as individual units but as part of an interconnected network called a capillary bed , or capillary plexus