This document discusses social epidemiology in public health research and the social determinants of health. It presents the Commission on Social Determinants of Health conceptual framework which shows how socioeconomic and political context, socioeconomic position, and structural determinants impact health inequities through intermediary determinants. The document also discusses how public health research integrates health and social epidemiology concepts to analyze risk factors related to public health problems. Finally, it presents the SOCIPID model for social epidemiology research and provides an example of how it was applied to research on coronary heart disease in women.