The shifted multiplicative model was developed by Cornelius and Seyedsadr in 1992.
SHMM is used to analyze the complete separability, genotypic separability, environmental separability, and inseparability of environment effects and genotypic effects.
Gregorius and Namkoong (1986) defined Separability as the property which is that cultivar effect is separable from environmental effect so that there is no rank.
The shifted multiplicative model (SHMM) is used in an exploratory step-down method for identifying subsets of environments in which genotypic effects are "separable" from environmental effects. Subsets of environments are chosen on the basis of a SHMM analysis of the entire data set. SHMM analyses of the subsets
may indicate a need for further subdivision and/or suggest that a different subdivision at the previous stage should be tried. The process continues until SHMM analysis indicates that a SHMM with only one multiplicative term and its "point of concurrence" outside (left or right) of the cluster of data points adequately fits the data in all subsets.
Advanced biometrical and quantitative genetics akshayAkshay Deshmukh
Additive and Multiplicative Model
Shifted Multiplicative Model
Analysis and Selection of Genotype
Methods and steps to select the best model
Bioplot and mapping genotype
Advanced biometrical and quantitative genetics akshayAkshay Deshmukh
Additive and Multiplicative Model
Shifted Multiplicative Model
Analysis and Selection of Genotype
Methods and steps to select the best model
Bioplot and mapping genotype
Association mapping, also known as "linkage disequilibrium mapping", is a method of mapping quantitative trait loci (QTLs) that takes advantage of linkage disequilibrium to link phenotypes to genotypes.Varioius strategey involved in association mapping is discussed in this presentation
Association genetics‟ or ‟association studies,” or ‟linkage disequilibrium mapping”.
Tool to resolve complex trait variation down to the sequence level by exploiting historical and evolutionary recombination events at the population level.
Natural population surveyed to determine MTA using LD.
Gene Action for Yield and its Attributes by Generation Mean Analysis in Brinj...AI Publications
Genetic studies assist the breeder in understanding the inheritance mechanism and enhance the efficiency of a breeding programme. Knowledge of gene action and their relative contribution in expression of character is of great importance. Eggplant yield depends on two components viz., fruit weight and number of fruits per plant. These traits are quantitative and therefore influenced by multiple genes. The objective of this study was to estimate the main gene effects (additive, dominance and digenic epistasis) and to determine the mode of inheritance for fruit Yield and its components. The generation mean analysis was employed in three crosses viz., Ac-2 x Annamalai, EP-45 x Annamalai and EP-89 X Annamalai to partition the genetic variance. Among the three crosses studied, the cross Ac-2 x Annamalai had complimentary type of epistasis along with significant additive gene effects and additive x additive interaction gene effects for all the three traits. Considering fruit yield per plant and its attributes, this cross was judged as the best cross for further selection programme.
Quantitative trait loci (QTL) analysis and its applications in plant breedingPGS
Abstract
Many agriculturally important traits such as grain yield, protein content and relative disease resistance are controlled by many genes and are known as quantitative traits (also polygenic or complex traits). A quantitative trait depends on the cumulative actions of many genes and the environment. The genomic regions that contain genes associated with a quantitative trait are known as quantitative trait loci (QTLs). Thus, a QTL could be defined as a genomic region responsible for a part of the observed phenotypic variation for a quantitative trait. A QTL can be a single gene or a cluster of linked genes that affect the trait. The effects of individual QTLs may differ from each other and change from environment to environment. The genetics of a quantitative trait can often be deduced from the statistical analysis of several segregating populations. Recently, by using molecular markers, it is feasible to analyze quantitative traits and identify individual QTLs or genes controlling the traits of interest in breeding programs.
Presentation delivered by Dr. Jesse Poland (Kansas State University, USA) at Borlaug Summit on Wheat for Food Security. March 25 - 28, 2014, Ciudad Obregon, Mexico.
http://www.borlaug100.org
Stability analysis and G*E interactions in plantsRachana Bagudam
Gene–environment interaction is when two different genotypes respond to environmental variation in different ways. Stability refers to the performance with respective to environmental factors overtime within given location. Selection for stability is not possible until a biometrical model with suitable parameters is available to provide criteria necessary to rank varieties / breeds for stability. Different models of stability are discussed.
GGEBiplot analysis of genotype × environment interaction in Agropyron interme...Innspub Net
In order to identify genotypes of Agropyron intermedium with high forage yield and stability an experiment was carried out in the Research station of Kermanshah Iran.The 11 accessions were sown in a randomized complete block design with three replications under rainfed and irrigated conditions during 2013-21-014 cropping deasons. Combined analysis of variance indicated high significant differences for location, genotype and G × E interaction (GEI) at 1% level of probability. Mean comparisons over environments introduced G4, G3 and G5 with maximum forage yield over rainfed and irrigated conditions. Minimum forage yield was attributed to genotype G1. GGEbiplot analysis exhibited that the first two principal components (PCA) resulted from GEI and genotype effect justified 99.37% of total variance in the data set. The four environments under investigation fell into two apparent groups: irrigated and rainfed. The presence of close associations among irrigated (E1 and E3) and rainfed (E2 and E4) conditions suggests that the same information about the genotypes could be obtained from fewer test environments, and hence the potential to reduce testing cost.The which-won-where pattern of GGEbiplot introduced genotypes G3 and G4 as stable with high forage yield for rainfed condition, while G5 was stable with high yield for irrigated condition. According to the comparison of the genotypes with the Ideal genotype accessions G4, G3 and G9 were more favorable than all the other genotypes. Get more articles at: http://www.innspub.net/volume-6-number-4-april-2015-jbes/
Association mapping, also known as "linkage disequilibrium mapping", is a method of mapping quantitative trait loci (QTLs) that takes advantage of linkage disequilibrium to link phenotypes to genotypes.Varioius strategey involved in association mapping is discussed in this presentation
Association genetics‟ or ‟association studies,” or ‟linkage disequilibrium mapping”.
Tool to resolve complex trait variation down to the sequence level by exploiting historical and evolutionary recombination events at the population level.
Natural population surveyed to determine MTA using LD.
Gene Action for Yield and its Attributes by Generation Mean Analysis in Brinj...AI Publications
Genetic studies assist the breeder in understanding the inheritance mechanism and enhance the efficiency of a breeding programme. Knowledge of gene action and their relative contribution in expression of character is of great importance. Eggplant yield depends on two components viz., fruit weight and number of fruits per plant. These traits are quantitative and therefore influenced by multiple genes. The objective of this study was to estimate the main gene effects (additive, dominance and digenic epistasis) and to determine the mode of inheritance for fruit Yield and its components. The generation mean analysis was employed in three crosses viz., Ac-2 x Annamalai, EP-45 x Annamalai and EP-89 X Annamalai to partition the genetic variance. Among the three crosses studied, the cross Ac-2 x Annamalai had complimentary type of epistasis along with significant additive gene effects and additive x additive interaction gene effects for all the three traits. Considering fruit yield per plant and its attributes, this cross was judged as the best cross for further selection programme.
Quantitative trait loci (QTL) analysis and its applications in plant breedingPGS
Abstract
Many agriculturally important traits such as grain yield, protein content and relative disease resistance are controlled by many genes and are known as quantitative traits (also polygenic or complex traits). A quantitative trait depends on the cumulative actions of many genes and the environment. The genomic regions that contain genes associated with a quantitative trait are known as quantitative trait loci (QTLs). Thus, a QTL could be defined as a genomic region responsible for a part of the observed phenotypic variation for a quantitative trait. A QTL can be a single gene or a cluster of linked genes that affect the trait. The effects of individual QTLs may differ from each other and change from environment to environment. The genetics of a quantitative trait can often be deduced from the statistical analysis of several segregating populations. Recently, by using molecular markers, it is feasible to analyze quantitative traits and identify individual QTLs or genes controlling the traits of interest in breeding programs.
Presentation delivered by Dr. Jesse Poland (Kansas State University, USA) at Borlaug Summit on Wheat for Food Security. March 25 - 28, 2014, Ciudad Obregon, Mexico.
http://www.borlaug100.org
Stability analysis and G*E interactions in plantsRachana Bagudam
Gene–environment interaction is when two different genotypes respond to environmental variation in different ways. Stability refers to the performance with respective to environmental factors overtime within given location. Selection for stability is not possible until a biometrical model with suitable parameters is available to provide criteria necessary to rank varieties / breeds for stability. Different models of stability are discussed.
GGEBiplot analysis of genotype × environment interaction in Agropyron interme...Innspub Net
In order to identify genotypes of Agropyron intermedium with high forage yield and stability an experiment was carried out in the Research station of Kermanshah Iran.The 11 accessions were sown in a randomized complete block design with three replications under rainfed and irrigated conditions during 2013-21-014 cropping deasons. Combined analysis of variance indicated high significant differences for location, genotype and G × E interaction (GEI) at 1% level of probability. Mean comparisons over environments introduced G4, G3 and G5 with maximum forage yield over rainfed and irrigated conditions. Minimum forage yield was attributed to genotype G1. GGEbiplot analysis exhibited that the first two principal components (PCA) resulted from GEI and genotype effect justified 99.37% of total variance in the data set. The four environments under investigation fell into two apparent groups: irrigated and rainfed. The presence of close associations among irrigated (E1 and E3) and rainfed (E2 and E4) conditions suggests that the same information about the genotypes could be obtained from fewer test environments, and hence the potential to reduce testing cost.The which-won-where pattern of GGEbiplot introduced genotypes G3 and G4 as stable with high forage yield for rainfed condition, while G5 was stable with high yield for irrigated condition. According to the comparison of the genotypes with the Ideal genotype accessions G4, G3 and G9 were more favorable than all the other genotypes. Get more articles at: http://www.innspub.net/volume-6-number-4-april-2015-jbes/
Genotype x Environment Interaction and Grain Yield Stability of Maize (Zea ma...Premier Publishers
Testing of genotypes in multi-environments is an important to estimate genotype x environment interaction (GEI) and identify stable genotypes with superior performance. The study was to evaluate different maize hybrids at multi-environments as well as to identify high yielding and stable maize hybrids. Twenty maize hybrids were tested across eight environments in a randomized complete block design in the 2015 cropping season. Combined analysis of variance and AMMI analysis showed that genotype, environment and GEI effect were highly significant (p < 0. 01) for grain yield. Genotype, environment and GEI explained 6.62, 84.87 and 4.50% of the total experimental variations, indicating the importance of environment for variations in grain yield. Mean grain yield of tested hybrids ranged from 4.98 t ha-1 in G2 to 7.51 t ha-1 in G16. As evident from significant GEI, performances of the hybrids were inconsistent across environments indicated that suitable to specific environment. Based on AMMI stability value and mean ranking of GGE biplot indicated that G18 (BH 546) had high grain yield (7.16 t ha-1) and more stable across tested environments. This study identified maize hybrids with high grain yield and stable across environments that need to be further validated for possible new maize variety release and or the newly released hybrid is used for possible commercial production.
Stability refers to the performance with respective changing environmental factors overtime within given location.
Selection for stability is not possible until a biometrical model with suitable parameters is available to provide criteria necessary to rank varieties / breeds for stability.
Nine groundnut varieties were tested across six environments in western Oromia, Ethiopia during 2013 main cropping season to evaluate the performance of groundnut varieties for kernel yield and their stability across environments. The varieties were arranged in randomized complete block design (RCBD) with three replications. Pooled analysis of variance for kernel yield showed significant (p≤0.01) differences among the varieties, environments and the genotype by environment interaction (GxE). Additive main effect and multiplicative interactions (AMMI) analysis showed highly significant (p≤0.01) differences for varieties, environments and their interaction on kernel yield. Similarly, the first and the second interaction principal component axis (IPCA1 and IPCA 2) were highly significant (p≤0.01) and explained 41.32 and 7.2% of the total GxE sum of squares, respectively. The environment, genotype and genotype by environment interaction accounted 14.7, 24.1 and 53.3% variations, respectively. This indicated the existence of considerable amounts of deferential response among the varieties to changes in growing environments and the deferential discriminating ability of the test environments. Shulamith and Bulki varieties showed the smallest genotype selection index (GSI) values and had the highest kernel yield and stability showing that these varieties had general adaptation in the tested environments. In the genotype and genotype by environment (GGE) biplot analysis, IPCA1 and IPCA 2 explained 63.5% and 22.4%, respectively, of genotype by environment interaction and made a total of 85.9%. GGE biplot analysis also confirmed Bulki and Shulamith varieties showed better stability and thus ideal varieties recommended for production in the test environments and similar agro-ecologies.
Speed Breeding is new technology to develop plants or breeding materials within a short possible time without affect seed viability and yield performance.
Crops undergo artificially DNA modifications for improvements are considered as genetically modified (GM) crops. These modifications could be in indigenous DNA or by the introduction of foreign DNA as transgenes. There are 29 different crops and fruit trees in 42 countries, which have been successfully modified for various traits like herbicide tolerance, insect/pest resistance, disease resistance and quality improvement. GM crops are grown worldwide and its area is significantly increasing every year. Many countries have very strict rules and regulations for GM crops and are also a trade barrier in some situations. Hence, identification and testing of crops for GM contents are important for the identity and legitimacy of the transgene to simplify the international trade. Normally, molecular identification is performed at three different levels, i.e., DNA, RNA and protein, and each level have its own importance in testing the nature and type of GM crops. In this chapter, the current scenario of GM crops and different molecular testing tools are described in brief.
A genetic marker is a gene or DNA sequence with a known location on a chromosome and associated with a particular gene or trait. It can be described as a variation, which may arise due to mutation or alteration in the genomic loci that can be observed. A genetic marker may be a short DNA sequence, such as a sequence surrounding a single base-pair change (single nucleotide polymorphism, SNP), or a long one, like mini & microsatellites.
Extranuclear inheritance or cytoplasmic inheritance is the transmission of genes that occur outside the nucleus. It is found in most eukaryotes and is commonly known to occur in cytoplasmic organelles such as mitochondria and chloroplasts or from cellular parasites like viruses or bacteria. Determining the contribution of organelle genes to plant phenotype is hampered by several factors, including the paucity of variation in the plastid and mitochondrial genomes. Mitochondria are organelles which function to transform energy as a result of cellular respiration. Chloroplasts are organelles which function to produce sugars via photosynthesis in plants and algae. The genes located in mitochondria and chloroplasts are very important for proper cellular function, yet the genomes replicate independently of the DNA located in the nucleus, which is typically arranged in chromosomes that only replicate one time preceding cellular division. The extranuclear genomes of mitochondria and chloroplasts however replicate independently of cell division. They replicate in response to a cell's increasing energy needs which adjust during that cell's lifespan. There is consistent difference between the results from reciprocal crosses; generally only the trait from female parent is transmitted. In most cases, there is no segregation in the F2 and subsequent generations.
Plant genetic engineering is one of the key technologies for crop improvement as well as an emerging approach for producing recombinant proteins in plants. Both plant nuclear and plastid genomes can be genetically modified, yet fundamental functional differences between the eukaryotic genome of the plant cell nucleus and the prokaryotic-like genome of the plastid will have an impact on key characteristics of the resulting transgenic organism. So, which genome, nuclear or plastid, to transform for the desired transgenic phenotype? In this paper we compare the advantages and drawbacks of engineering plant nuclear and plastid genomes to generate transgenic plants with the traits of interest, and evaluate the pros and cons of their use for different biotechnology and basic research applications. The chloroplast is a pivotal organelle in plant cells and eukaryotic algae to carry out photosynthesis, which provides the primary source of the world’s food. The expression of foreign genes in chloroplasts offers several advantages over their expression in the nucleus: high-level expression, no position effects, no vector sequences allowing stable transgene expression. In addition, transgenic chloroplasts are generally not transmitted through pollen grains because of the cytoplasmic localization. In the past two decades, great progress in chloroplast engineering has been made.
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
Letter from the Congress of the United States regarding Anti-Semitism sent June 3rd to MIT President Sally Kornbluth, MIT Corp Chair, Mark Gorenberg
Dear Dr. Kornbluth and Mr. Gorenberg,
The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
harassment and intimidation at the Massachusetts Institute of Technology (MIT). Failing to act decisively to ensure a safe learning environment for all students would be a grave dereliction of your responsibilities as President of MIT and Chair of the MIT Corporation.
This Congress will not stand idly by and allow an environment hostile to Jewish students to persist. The House believes that your institution is in violation of Title VI of the Civil Rights Act, and the inability or
unwillingness to rectify this violation through action requires accountability.
Postsecondary education is a unique opportunity for students to learn and have their ideas and beliefs challenged. However, universities receiving hundreds of millions of federal funds annually have denied
students that opportunity and have been hijacked to become venues for the promotion of terrorism, antisemitic harassment and intimidation, unlawful encampments, and in some cases, assaults and riots.
The House of Representatives will not countenance the use of federal funds to indoctrinate students into hateful, antisemitic, anti-American supporters of terrorism. Investigations into campus antisemitism by the Committee on Education and the Workforce and the Committee on Ways and Means have been expanded into a Congress-wide probe across all relevant jurisdictions to address this national crisis. The undersigned Committees will conduct oversight into the use of federal funds at MIT and its learning environment under authorities granted to each Committee.
• The Committee on Education and the Workforce has been investigating your institution since December 7, 2023. The Committee has broad jurisdiction over postsecondary education, including its compliance with Title VI of the Civil Rights Act, campus safety concerns over disruptions to the learning environment, and the awarding of federal student aid under the Higher Education Act.
• The Committee on Oversight and Accountability is investigating the sources of funding and other support flowing to groups espousing pro-Hamas propaganda and engaged in antisemitic harassment and intimidation of students. The Committee on Oversight and Accountability is the principal oversight committee of the US House of Representatives and has broad authority to investigate “any matter” at “any time” under House Rule X.
• The Committee on Ways and Means has been investigating several universities since November 15, 2023, when the Committee held a hearing entitled From Ivory Towers to Dark Corners: Investigating the Nexus Between Antisemitism, Tax-Exempt Universities, and Terror Financing. The Committee followed the hearing with letters to those institutions on January 10, 202
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
Palestine last event orientationfvgnh .pptxRaedMohamed3
An EFL lesson about the current events in Palestine. It is intended to be for intermediate students who wish to increase their listening skills through a short lesson in power point.
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdfTechSoup
In this webinar you will learn how your organization can access TechSoup's wide variety of product discount and donation programs. From hardware to software, we'll give you a tour of the tools available to help your nonprofit with productivity, collaboration, financial management, donor tracking, security, and more.
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
2. GE interaction
Most of the economic traits in plant breeding are
quantitative nature.
Phenotypes values of the Cultivar/Genotypes are the
combination of genotype (G) and environment (E) values, and
their interactions (GE).
defined as the variation in relative performance of
genotypes in different environmental conditions.
In Crop Improvement program, because it complicates
identification and selection of superior genotypes thereby
reducing genetic progress.
3.
4. Shifted multiplicative model was developed by Cornelius
and Seyedsadr in 1992
SHMM is used to analyze the complete separability,
genotypic separability, environmental separability, and
inseparability of environment effects and genotypic effects.
Gregorius and Namkoong (1986) defined Separability as the
property which is that cultivar effect is separable from
environmental effect so that there is no rank.
5. Cornelius et al. (1992) defined sufficient conditions for the
absence of statistically significant:
(1) SHMM1 is an adequate model for fitting the data and
(2) Primary effects of environments have the same sign.
Non-significant environmental rank-change interactions
is indicated when SHMM1 is an adequate model holds
and
(3) Primary effects of genotypes have the same sign.
The absence of significance of both environmental rank-
change interactions and genotypic rank-change
interactions occurs when (1), (2) and (3) all hold.
8. SHMM with t multiplicative terms (SHMMt) is represented
by:-
β= Shift parameter
γjk= ktheffects of jth genotype
λk= Scaling constant
αik= kth effects of ith environment
eij = residual error
Note: kth If SHMM is adequate in single multiplicative term (k=1), is
refers to primary effect of ith environment & jth genotype (αi1 & γj1)
respectively
9. ANOVA for SHMM
The SC and SC/SM tests are the only significance tests which are available to use.
10.
11.
12.
13.
14.
15.
16.
17. AMMI model
AMMI is a combination of ANOVA for the main effects of the genotypes and the
environment together with principal components analysis (PCA) the genotype-
environment interaction.
AMMI first calculate genotype and environment environment additive effect using
analysis of variance (ANOVA) and then analyse residual from
these model using principal components analysis (PCA).
The AMMI analysis provided
1. A better understanding of the GEI through analysis of variance.
2. It facilitated identification of genotypes possessing stable yields as well as
discriminating environments through the biplot display.
3. Specificity in adaptability of the genotypes to specific environments.
4. The scientific information obtained, could be of considerable importance in
developing location specific breeding strategies and selecting stable genotypes in
breeding programme.
Conclusion
The AMMI analysis provided a better understanding of the GEI through analysis of
variance, facilitated identification of genotypes possessing stable yields as well as
discriminating environments through the biplot display and specificity in adaptability
of the genotypes to specific environments.