Sculptris is a 3D sculpting software that has two main modes: Sculpt mode and Paint mode. In Sculpt mode, the user can manipulate digital clay to sculpt. Paint mode allows adding textures but does not allow further sculpting. The document provides tips for using various brushes and shortcuts in Sculptris. It recommends having reference images and planning the sculpting process from overall shape to details before starting. When sculpting, it advises being patient, completing symmetrical details first before removing symmetry, and practicing to improve skills.