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Celebral Death 
Transplantation 
ŞERİFE GÜL ŞİMŞEK 
Akdeniz üniversitesi tıp fakültesi 
hastanesi
CONTENT 
 Death 
 Celebral Death 
 Donor Care 
 Transplantation 
 Results
WHAT IS DEATH? 
 Cardiopulmonary Death 
 It is the arrest in the cardiac functions 
and adiaphoresis. 
 Celebral Death 
 Cerebral death is the death of brain cells.
DEFINITION OF DEATH FOR AES 
((American Electroencephalograpic 
 DEATH : 
 Theirreversible arrest of respiration and 
circulation 
 The irreversible arrest of brain and brain 
stem reflexes 
 Brain blood supply exists but oedema 
continues and after a while, circulation 
fails and blood suppy stops.
WHAT IS CEREBRAL DEATH?
HISTORY OF CELEBRAL DEATH 
 1959: Dr. Mallret Le Coma Depasse 
 1968: Harvard University 
 1976: Royal Medicine Collage 
 1981: President’s Commission 
 1995: Neurology Academy
CEREBRAL DEATH PERSISTENT VEGETATIVE STATE 
 *connected to 
respiratory tract 
 * loss in 24-36 hours 
 *Impossible to revive 
 *Patient continues to 
aspirate 
 *The patients may live 
for months or even 
years 
 *The patients may have 
the chance of survival in 
some cases. 
 * The patients react to 
painful stimulus
DIAGNOSIS OF CEREBRAL 
DEATH 
 *While it seems very related among the 
countries, there are some differences 
with respect to the diagnosis tests. 
 *After diagnosed with cerebral death 
clinically in Turkey, they run an apnea 
test and the diagnosis is confirmed with 
another supportive test.
LEGAL REGULATIONS IN 
TURKEY
LEGAL REGULATIONS IN 
TURKEY
LEGAL REGULATIONS IN 
TURKEY
DIAGNOSIS OF CEREBRAL 
DEATH-2012 
 (1)The preconditions required in the diagnosis of 
cerebral death 
 a)Specify of the reason of coma 
 b)Specify of that the brain damage is extensive and 
irreversible 
 c)Central body tempereture be ≥32 C 
 d)No existence of Hypotansive shock chart 
 e)Ostracising the medicine affects and intoxications 
that can provide irreversing from coma 
 f)No existence of metabolic , electrolit and acid-base 
disorders that will explain the case independently from 
the brain damage
DIAGNOSIS OF CEREBRAL 
DEATH-2012 
 (2) On the condition that all the conditions are detected in the first 
paragraph, following points are required for the cerebral death. 
 A)Deep coma state ( fully responselessness state) 
 B)Not receiving the brain stem reflexes 
 1)no pupilla response to the bright light ,central lined 
and dilated 
 2) Absence of oculacephalic and vestibula-ocular 
reflexes 
 3)Absence of cornea reflexes 
 4) Absence of pharyngeal and tracheal reflexes 
 C) No existence of spontenous aspiration effort and 
positive apnea test.
DIAGNOSIS OF CEREBRAL 
DEATH-2012 
 (3 ) Normothermia, normotension and normovolemia 
preconditions are provided for running an apnea test.It should be 
provided that PaCO2 be 35-45 mmHg and PaO2 be over 200 
mmHg with the modality of suitable mechanic ventilation under 
these circumstances.After providing all these conditions, patient 
should be detached from mechanical aspiratory support unit and 
intratracheal oxigen should be applied.If there is no spontenous 
aspiration at the end of the test in spite of the fact that the PaCO2 
≥60 and/or PaCO2 base value rises 20 mmHg or more , apnea 
test is positive. 
 (4) In medical situations such as 
pneumothorax,pneumomediastinum when apnea test is not 
possible, a supportive test evaluating the arrest in brain 
circulation determined by the board of doctors is run and cerebral 
death detection is completed if the test result matches the 
cerebral death diagnosis.
DIAGNOSIS OF CEREBRAL 
DEATH-2012 
 (5) The following findings do not constitute an 
impediment for the diagnosis of cerebral 
death. 
 a) Reception of deep tendon reflexes 
 b)Reception of shallow reflexes 
 c) Presence of Babisnki sign 
 d)Presence of spinal reflexes and 
automatisms 
 e)Presence of perspiration , reddening , high 
temperature and tachycardia 
 f)No existence of Diabetes insipidus,
DIAGNOSIS OF CEREBRAL 
DEATH-2012 
 (6) In cases diagnosed with cerebral death ; 
 a)The clinical view in the first neurologic examination when the 
patient is diagnosed should continue without change in the 
second neurologic examination performed after 
 48 hours for Newborns(younger than 2 months old) 
 24 hours for ages 2 months old – 1 year old 
 12 hours for children over 1 year old and adults 
 24 hours for anoxic cerebral death 
 b) In cases diagnosed with clinical celebral death , cerebral death 
diagnosis is confirmed with 2 supportive test in the new born 
(younger than 2 months old) group , with one laboratory 
procedure accepted by the board of doctors in the cases who are 
2 months old and over. 
 c) There is no need to wait for the second neurological 
examination if a brain circulation evaluation test is run and the 
results of the tests are positive for those who were clinically 
diagnosed with cerebral death.
Diagnostic Criterias Supportive tests 
 Tests showing that 
the brain circulation 
is fully arrested 
 Transcranial Doppler 
 Cerebnal 
Angiography 
 *Cerebnal Perfusion 
Scintigraphy 
 Tests showing the 
loss of bioelectrical 
activity 
 *EEG 
 *Alerted Potentials
Beyin 
ölümünü 
desteklemez 
Beyin 
ölümünü 
destekler 
Beyin 
ölümünü 
destekler
ANJİOGRAFİ
SİNTİGRAFİ
ELEKTROENSEFALOGRAFİ
Attention !!!! 
 It is obliged that the group of doctors to 
diagnose the cerebral death be totally 
different from the team performing the 
transplantation.
CEREBRAL DEATH and PATIENT 
RELATIVE 
 *The state of patient’s heart continues 
beating after the diagnosis of cerebral 
death or brain stem death affects the 
patient relative but ; 
 *If the brain stem dies, brain doesn’t 
function and heart functions stops in a 
short
AFFECT THE DECISION OF 
ORGAN DONATION 
Patient Relatives may develop such thoughts 
and feelings as ; 
 Not enough care to their patients 
 Monetary gain 
 Organ trading 
 Disintegration of body 
 Anger 
 As a result of this , 
 *They may not trust the hospital.
Transplantasyon Ekibine Güven 
Katılıyorum 
Fikrim 
Yok 
Katılmıyorum 
Türkiye’de Doktorlar Beyin Ölümü 
Kararını Doğru Verecek Durumdadır 
%63,2 %27,6 %9,2 
Organlarımı Bağışlarsam Tedavim 
Yeterince Yapılmadan veya Tam Ölüm 
Gerçekleşmeden Organlarım Alınabilir 
%19,8 %28,2 %52,0 
Organlarımı Bağışlarsam, Onlar Uygun 
Şekilde Kullanılmaz ve Başka Bir İnsana 
Fayda Sağlamaz. Yani Vücudum 
Boşuna Kesilmiş Olur 
%8,0 %25,2 %66,8 
Organlarımı Bağışlarsam, Onlar 
Gerçekten İhtiyacı Olanlara Değil Çok 
Parası Olanlara Takılabilir 
%24,8 %32,0 %43,2
REASONS OF DONOR ORGAN 
LOSS 
 *Prolongation of diagnosis of cerebral 
death 
 *prolongation of documantation 
 *prolongation of organ extraction 
 *Disorder in coordination (logistic) 
 *Physical transportation of organ to the 
recipient ( Time Period)
ROLES OF INTENSIVE CARE UNIT 
 *Diagnosing the cerebral death in the shortest 
time possible 
 *Sustaining the organ protective treatment 
 *Providing an accurate and healthy 
communication between the donor’s family 
and transplantation coordination center 
 *Intensive care is the one who treats patients, 
not the one who requires donation
WHAT IS DONOR CARE? 
 *Donor care is the patient’s care after the 
cerebral death 
 *It is a simultanous care of a few 
recipient
MONİTORİZASYON 
SÜREKLİ 
• EKG, 
• İnvaziv Arter 
Basıncı 
• SVB 
• Pulsoksimetre 
• Vücut Isısı 
(mesane rektal 
ozofajiyal) 
SAATLİK 
• İdrar 
Çıkışı 
HER 4-6 SAATTE BİR 
• Kan Şekeri 
• Na,CI,K 
• Üre,Kreatin 
• Hemogram 
• Koagulasyon 
Testleri 
• Arterial 
Kangazı 
MONİTÖRİZASYON
GÖZLEM HEDEFLERİ 
100’ LER KURALI 
 Kan basıncı~100mmHg 
 Diürez ~ 100 ml.st-1 
 PaO2 ~ 100 mmHg 
 Hb ~ 100 gr.lt-1 
 Vücut ısısı ~ 36 °C 
 Glukoz 140-200 mg/dl 
 pH ~ 7.40 
 PaCO2 35-45 mmHg 
 SVB ~ 10 mmHg 
 OAB >65mmHg 
Na+ <160 mEq /lt
CEREBRAL DEATH 
PHYSIOLOGICAL CHANGES 
 * Immunity system disorder 
 *Aqueous electrolyte balance disorder 
 *Hypotension 
 *Arrhythmia 
 *Endocrine Changes 
 *Diabetus insipitus 
 *Hypothermia
COMMUNICATION WITH PATIENT 
RELATIVES-1 
 *The patient family shoud be satisfied 
with the care and attention to their 
patients 
 *We should gain trust of patient relatives 
through our body language and facial 
expressions 
 *We should choose the most ideal family 
relative to speak to 
 *We shouldn’t use medical terms.
COMMUNICATION WITH PATIENT 
RELATIVES-2 
 We should give the patient’s relatives 
adequate information about the care and 
treatment 
 We should have a clear language about 
the death time. 
 We should allow family to talk and 
discharge 
 We should make them feel like a friend
COMMUNICATION WITH PATIENT 
RELATIVES-3 
 We should provide the entrence of 
relatives for the adoptation of family 
 We should let them take leave for the 
last time in intensive care unit 
 We should listen to the family’s wishes 
and requirements and answer their 
questions
U-TURN 
Aggressive 
treatment 
Deteriorising 
state 
Preparing the family 
for the negative end 
Legal diagnosis 
Announcing the death and support to the 
family 
Life saving 
transplantation 
Supporting the donor 
management 
Discussing the donation
TRANSPLANTATION 
 *It is the changing procedure of 
disfunctioning organ with an intact organ 
(extracted from live or dead donor) 
 *Transplantation is the best option for the 
treatment of End Term Organ Failure 
patients 
 * It is applied in order to increase the life 
quality and duration of patients
HISTORIC ASPECT 
 Cosmas and Damian 
transplating a black 
donor’s leg to a white 
female
HISTORIC ASPECT 
 1962 J.Murray Kidney 
 1963 T.Starzl Liver Cadaver 
 1963 JD.Hardy Lung (donor)
TURKISH HISTORY 
 1979 Law of Transplantation 
 1993 Regulation for Transplantation 
Centers 
 2000 Regulation for Organ and Tissue 
Tranplantation
AKDENİZ ÜNİVERCİTY
AKDENİZ ÜNİVERCİTY 
PROF. DR ÖMER ÖZKAN
OUR CEREBRAL DEATH AND DONATION RATES 
Year Cerebral Death 
Medical 
Contraindicati 
on 
Donation 
Bağış oranı 
2000 25 4 6 %24 
2001 47 10 16 %43 
2002 46 3 22 %49 
2003 37 6 18 %61 
2004 46 11 11 %34 
2005 60 4 21 %34
Year Cerebral Death 
Medical 
Contraindicati 
on 
Donation 
Bağış oranı 
2006 35 7 10 %28 
2007 17 1 5 %29 
2008 
4 
0 
2 
%50 
2009 
16 
2 
4 
%28 
2010 
21 
0 
11 
%49 
2011 
23 
1 
4 
%14 
OUR CEREBRAL DEATH AND DONATION RATES
Year Cerebral Death Aile kabul Aile red 
aile 
görüşmeye 
gelmedi 
2011 
2012 
2013 
2014 
28 
25 
22 
35 
5 
9 
11 
6 
22 
15 
10 
24 
1 
1 
_ 
2 
OUR CEREBRAL DEATH AND DONATION RATES
ORGAN DONATION AND NURSING 
 *Nurses should support the family from the 
moment of informing the family of the cerebral 
death to the moment of decision 
 *Intensive care nurses should be educated 
and motivated in cerebral death and donor 
care 
 *Positive effect has been stated in the results 
with the rising information in organ donation 
 *Nurses shouldn’t forget that they maintain 
many cares simultanously
CONCLUSION 
 It is important that we benefit from the 
limited number of donations effectively 
with respect to minimise the patient loss 
 Reports in the press affects the patient 
relatives, thus the best press 
communication method should be set up 
 It is extremely important that we know 
the process of cerebral death and 
monitoring
CONCLUSION 
 It is essential that we have experienced 
personnel, high technology and 
mechanical support for the nursing care 
and treatments 
 Application of scheduled nursing 
initiatives affects the prognosis of donor 
positively and increases the quality of 
organ
CONCLUSION 
 *When the patient dies in spite of all the 
interventions, organ donation is a 
positive result of a tragic situation. 
 Any word you say may make a 
difference between a Yes or No.
Salon 2 14 kasim 09.30 10.30 şeri̇fe gül şi̇mşek-ing

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Salon 2 14 kasim 09.30 10.30 şeri̇fe gül şi̇mşek-ing

  • 1. Celebral Death Transplantation ŞERİFE GÜL ŞİMŞEK Akdeniz üniversitesi tıp fakültesi hastanesi
  • 2. CONTENT  Death  Celebral Death  Donor Care  Transplantation  Results
  • 3. WHAT IS DEATH?  Cardiopulmonary Death  It is the arrest in the cardiac functions and adiaphoresis.  Celebral Death  Cerebral death is the death of brain cells.
  • 4. DEFINITION OF DEATH FOR AES ((American Electroencephalograpic  DEATH :  Theirreversible arrest of respiration and circulation  The irreversible arrest of brain and brain stem reflexes  Brain blood supply exists but oedema continues and after a while, circulation fails and blood suppy stops.
  • 6. HISTORY OF CELEBRAL DEATH  1959: Dr. Mallret Le Coma Depasse  1968: Harvard University  1976: Royal Medicine Collage  1981: President’s Commission  1995: Neurology Academy
  • 7. CEREBRAL DEATH PERSISTENT VEGETATIVE STATE  *connected to respiratory tract  * loss in 24-36 hours  *Impossible to revive  *Patient continues to aspirate  *The patients may live for months or even years  *The patients may have the chance of survival in some cases.  * The patients react to painful stimulus
  • 8. DIAGNOSIS OF CEREBRAL DEATH  *While it seems very related among the countries, there are some differences with respect to the diagnosis tests.  *After diagnosed with cerebral death clinically in Turkey, they run an apnea test and the diagnosis is confirmed with another supportive test.
  • 12. DIAGNOSIS OF CEREBRAL DEATH-2012  (1)The preconditions required in the diagnosis of cerebral death  a)Specify of the reason of coma  b)Specify of that the brain damage is extensive and irreversible  c)Central body tempereture be ≥32 C  d)No existence of Hypotansive shock chart  e)Ostracising the medicine affects and intoxications that can provide irreversing from coma  f)No existence of metabolic , electrolit and acid-base disorders that will explain the case independently from the brain damage
  • 13. DIAGNOSIS OF CEREBRAL DEATH-2012  (2) On the condition that all the conditions are detected in the first paragraph, following points are required for the cerebral death.  A)Deep coma state ( fully responselessness state)  B)Not receiving the brain stem reflexes  1)no pupilla response to the bright light ,central lined and dilated  2) Absence of oculacephalic and vestibula-ocular reflexes  3)Absence of cornea reflexes  4) Absence of pharyngeal and tracheal reflexes  C) No existence of spontenous aspiration effort and positive apnea test.
  • 14. DIAGNOSIS OF CEREBRAL DEATH-2012  (3 ) Normothermia, normotension and normovolemia preconditions are provided for running an apnea test.It should be provided that PaCO2 be 35-45 mmHg and PaO2 be over 200 mmHg with the modality of suitable mechanic ventilation under these circumstances.After providing all these conditions, patient should be detached from mechanical aspiratory support unit and intratracheal oxigen should be applied.If there is no spontenous aspiration at the end of the test in spite of the fact that the PaCO2 ≥60 and/or PaCO2 base value rises 20 mmHg or more , apnea test is positive.  (4) In medical situations such as pneumothorax,pneumomediastinum when apnea test is not possible, a supportive test evaluating the arrest in brain circulation determined by the board of doctors is run and cerebral death detection is completed if the test result matches the cerebral death diagnosis.
  • 15. DIAGNOSIS OF CEREBRAL DEATH-2012  (5) The following findings do not constitute an impediment for the diagnosis of cerebral death.  a) Reception of deep tendon reflexes  b)Reception of shallow reflexes  c) Presence of Babisnki sign  d)Presence of spinal reflexes and automatisms  e)Presence of perspiration , reddening , high temperature and tachycardia  f)No existence of Diabetes insipidus,
  • 16. DIAGNOSIS OF CEREBRAL DEATH-2012  (6) In cases diagnosed with cerebral death ;  a)The clinical view in the first neurologic examination when the patient is diagnosed should continue without change in the second neurologic examination performed after  48 hours for Newborns(younger than 2 months old)  24 hours for ages 2 months old – 1 year old  12 hours for children over 1 year old and adults  24 hours for anoxic cerebral death  b) In cases diagnosed with clinical celebral death , cerebral death diagnosis is confirmed with 2 supportive test in the new born (younger than 2 months old) group , with one laboratory procedure accepted by the board of doctors in the cases who are 2 months old and over.  c) There is no need to wait for the second neurological examination if a brain circulation evaluation test is run and the results of the tests are positive for those who were clinically diagnosed with cerebral death.
  • 17. Diagnostic Criterias Supportive tests  Tests showing that the brain circulation is fully arrested  Transcranial Doppler  Cerebnal Angiography  *Cerebnal Perfusion Scintigraphy  Tests showing the loss of bioelectrical activity  *EEG  *Alerted Potentials
  • 18. Beyin ölümünü desteklemez Beyin ölümünü destekler Beyin ölümünü destekler
  • 22. Attention !!!!  It is obliged that the group of doctors to diagnose the cerebral death be totally different from the team performing the transplantation.
  • 23. CEREBRAL DEATH and PATIENT RELATIVE  *The state of patient’s heart continues beating after the diagnosis of cerebral death or brain stem death affects the patient relative but ;  *If the brain stem dies, brain doesn’t function and heart functions stops in a short
  • 24. AFFECT THE DECISION OF ORGAN DONATION Patient Relatives may develop such thoughts and feelings as ;  Not enough care to their patients  Monetary gain  Organ trading  Disintegration of body  Anger  As a result of this ,  *They may not trust the hospital.
  • 25. Transplantasyon Ekibine Güven Katılıyorum Fikrim Yok Katılmıyorum Türkiye’de Doktorlar Beyin Ölümü Kararını Doğru Verecek Durumdadır %63,2 %27,6 %9,2 Organlarımı Bağışlarsam Tedavim Yeterince Yapılmadan veya Tam Ölüm Gerçekleşmeden Organlarım Alınabilir %19,8 %28,2 %52,0 Organlarımı Bağışlarsam, Onlar Uygun Şekilde Kullanılmaz ve Başka Bir İnsana Fayda Sağlamaz. Yani Vücudum Boşuna Kesilmiş Olur %8,0 %25,2 %66,8 Organlarımı Bağışlarsam, Onlar Gerçekten İhtiyacı Olanlara Değil Çok Parası Olanlara Takılabilir %24,8 %32,0 %43,2
  • 26. REASONS OF DONOR ORGAN LOSS  *Prolongation of diagnosis of cerebral death  *prolongation of documantation  *prolongation of organ extraction  *Disorder in coordination (logistic)  *Physical transportation of organ to the recipient ( Time Period)
  • 27. ROLES OF INTENSIVE CARE UNIT  *Diagnosing the cerebral death in the shortest time possible  *Sustaining the organ protective treatment  *Providing an accurate and healthy communication between the donor’s family and transplantation coordination center  *Intensive care is the one who treats patients, not the one who requires donation
  • 28. WHAT IS DONOR CARE?  *Donor care is the patient’s care after the cerebral death  *It is a simultanous care of a few recipient
  • 29. MONİTORİZASYON SÜREKLİ • EKG, • İnvaziv Arter Basıncı • SVB • Pulsoksimetre • Vücut Isısı (mesane rektal ozofajiyal) SAATLİK • İdrar Çıkışı HER 4-6 SAATTE BİR • Kan Şekeri • Na,CI,K • Üre,Kreatin • Hemogram • Koagulasyon Testleri • Arterial Kangazı MONİTÖRİZASYON
  • 30. GÖZLEM HEDEFLERİ 100’ LER KURALI  Kan basıncı~100mmHg  Diürez ~ 100 ml.st-1  PaO2 ~ 100 mmHg  Hb ~ 100 gr.lt-1  Vücut ısısı ~ 36 °C  Glukoz 140-200 mg/dl  pH ~ 7.40  PaCO2 35-45 mmHg  SVB ~ 10 mmHg  OAB >65mmHg Na+ <160 mEq /lt
  • 31. CEREBRAL DEATH PHYSIOLOGICAL CHANGES  * Immunity system disorder  *Aqueous electrolyte balance disorder  *Hypotension  *Arrhythmia  *Endocrine Changes  *Diabetus insipitus  *Hypothermia
  • 32.
  • 33. COMMUNICATION WITH PATIENT RELATIVES-1  *The patient family shoud be satisfied with the care and attention to their patients  *We should gain trust of patient relatives through our body language and facial expressions  *We should choose the most ideal family relative to speak to  *We shouldn’t use medical terms.
  • 34. COMMUNICATION WITH PATIENT RELATIVES-2  We should give the patient’s relatives adequate information about the care and treatment  We should have a clear language about the death time.  We should allow family to talk and discharge  We should make them feel like a friend
  • 35. COMMUNICATION WITH PATIENT RELATIVES-3  We should provide the entrence of relatives for the adoptation of family  We should let them take leave for the last time in intensive care unit  We should listen to the family’s wishes and requirements and answer their questions
  • 36. U-TURN Aggressive treatment Deteriorising state Preparing the family for the negative end Legal diagnosis Announcing the death and support to the family Life saving transplantation Supporting the donor management Discussing the donation
  • 37. TRANSPLANTATION  *It is the changing procedure of disfunctioning organ with an intact organ (extracted from live or dead donor)  *Transplantation is the best option for the treatment of End Term Organ Failure patients  * It is applied in order to increase the life quality and duration of patients
  • 38. HISTORIC ASPECT  Cosmas and Damian transplating a black donor’s leg to a white female
  • 39. HISTORIC ASPECT  1962 J.Murray Kidney  1963 T.Starzl Liver Cadaver  1963 JD.Hardy Lung (donor)
  • 40. TURKISH HISTORY  1979 Law of Transplantation  1993 Regulation for Transplantation Centers  2000 Regulation for Organ and Tissue Tranplantation
  • 42. AKDENİZ ÜNİVERCİTY PROF. DR ÖMER ÖZKAN
  • 43. OUR CEREBRAL DEATH AND DONATION RATES Year Cerebral Death Medical Contraindicati on Donation Bağış oranı 2000 25 4 6 %24 2001 47 10 16 %43 2002 46 3 22 %49 2003 37 6 18 %61 2004 46 11 11 %34 2005 60 4 21 %34
  • 44. Year Cerebral Death Medical Contraindicati on Donation Bağış oranı 2006 35 7 10 %28 2007 17 1 5 %29 2008 4 0 2 %50 2009 16 2 4 %28 2010 21 0 11 %49 2011 23 1 4 %14 OUR CEREBRAL DEATH AND DONATION RATES
  • 45. Year Cerebral Death Aile kabul Aile red aile görüşmeye gelmedi 2011 2012 2013 2014 28 25 22 35 5 9 11 6 22 15 10 24 1 1 _ 2 OUR CEREBRAL DEATH AND DONATION RATES
  • 46. ORGAN DONATION AND NURSING  *Nurses should support the family from the moment of informing the family of the cerebral death to the moment of decision  *Intensive care nurses should be educated and motivated in cerebral death and donor care  *Positive effect has been stated in the results with the rising information in organ donation  *Nurses shouldn’t forget that they maintain many cares simultanously
  • 47. CONCLUSION  It is important that we benefit from the limited number of donations effectively with respect to minimise the patient loss  Reports in the press affects the patient relatives, thus the best press communication method should be set up  It is extremely important that we know the process of cerebral death and monitoring
  • 48. CONCLUSION  It is essential that we have experienced personnel, high technology and mechanical support for the nursing care and treatments  Application of scheduled nursing initiatives affects the prognosis of donor positively and increases the quality of organ
  • 49. CONCLUSION  *When the patient dies in spite of all the interventions, organ donation is a positive result of a tragic situation.  Any word you say may make a difference between a Yes or No.