This document discusses biosafety and biosecurity in laboratories. It defines laboratory biosafety as containment practices to prevent exposure to pathogens, and biosecurity as protecting valuable biological materials. It also defines bioterrorism, biohazards, risk, and biomedical waste. The document outlines objectives of biological safety including protecting workers, maintaining a safe work environment, and preventing spread of contaminants. It lists 12 rules of biosafety such as proper training, handling all biological material as potentially infectious, using appropriate biosafety levels, and reporting any accidents.