This document discusses laboratory biosecurity and defines it as protecting, controlling, and accounting for valuable biologic material to prevent unauthorized access, loss, theft, misuse, diversion, or intentional release. It notes that increased security is needed to safeguard public health from potential bioterrorism. Valuable biologic material includes pathogens, toxins, vaccines, genetically modified organisms, and cellular components. Biosecurity is important to prevent dual-use research of concern from being used for biowarfare or terrorism. The principles of biosecurity include restricted information and communication, coding of samples, barriers in emergencies, and addressing gaps between senders and receivers. Components of lab biosecurity include physical security, personnel security, material

1. LABORATORY
BIOSECURITY
By Dr. Abdoalati Alswehli
MSc Human Anatomy
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2. INTRODUCTION
 Today, the nation is facing a new challenge
in safeguarding the public health from
potential domestic or international terrorism
involving the use of dangerous biological
agents or toxins.
 So, increased security within the
microbiological and biomedical community
in order to protect biological pathogens and
toxins from theft, loss, or misuse is
mandatory. 2

3. DEFINITION
Laboratory biosecurity, is protection,
control and accountability for valuable
biologic material (VBM) in order to
prevent their unauthorized access,
loss, theft, misuse, diversion, or
intentional release.
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4.  So, biosecurity is protecting agents from bad
people.
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5.  Limit access to areas that contain certain biological
agents or assets.
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6. WHAT VALUABLE BIOLOGIC MATERIAL
(VBM) IS ?
 Collections and references strains ( cell culture
lines ).
 Pathogens and toxins .. Should address the dual-
use nature.
 Vaccines and other pharmaceutical products.
 Yeast and bacteria related to development and
production of food products.
 Genetically modified organism(GOM).
 Non-pathogenic microorganism
 Cellular components and genetic elements ( DNA
and /or RNA). 6

7. WHY WE HAVE TO THINK ABOUT
BIOSECURITY ?
 Because those dangerous agent can be :
 Dual-use research of concern (DURC)
means can be use either for good or bad purposes.
 Bio-warfare/terrorist
biological weapons and Anthrax.
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8. CATEGORIES OF BIOTERRORISM AGENTS
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9. PRINCIPLES OF BIOSECURITY
1. restricted information.
2. Restricted communication.
3. Coding of samples in storage.
4. Close barrier in case of
emergency .
5. Tackle the gap between sender
and receiver .
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10. COMPONENTS OF LAB-BIOSECURITY
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11. Physical security
We want to keep agents inside
the lab and to prevent them from
someone who had bad intention to
steal it.
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12. PHYSICAL PROTECTION
 Physical security and accesses control, Concentric
 Layers of protection :
 Property protection areas (1)
Low risk assets
( ground, public access offices )
 Limited area (2)
Moderate risk assets e.g. laboratories
 Exclusion areas (3)
High risk assets .
e.g. high containment lab, biological agents/toxins.
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2
3
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13.  Personnel security
is the management of staff to assist in the
protection people, information and assets.
 The purpose of personnel security is to provide a
level of assurance.
 Personnel security aims to:
 reduce the risk of loss or damage.
 minimise potential for misuse.
 support a culture of protective security.
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14. MATERIAL USE AND ACCOUNTABILITY
 Material accountability is essential part of good
laboratory practice.
 Material accountability requires that you know:
 What material you have.
 Who is responsible for it.
 Where it is located
 Who has access to it .
 How it’s controlled
and documented.
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15.  Transfer security
The agents which already in lab should be monitoring
where it goes, what u did with those agents is under
the biosecurity, even when destroy , you have to have
document saying that these agents already been
destroyed .
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16.  Information security
Information which come up from agents
have to share these information at least in the
institute.
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17. REFERENCES
 Biosafety and biosecurity lecture by Dr. Dewajani
purnomosari
 PPT slides Dr. Subhash J. Bhore
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18. Thanks!
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