This lecture introduces biosafety and biosecurity. Biosafety refers to containment practices to prevent exposure to pathogens, while biosecurity aims to prevent the spread of harmful organisms. Biorisk encompasses both biosafety and biosecurity risks associated with biological materials. Key components of biorisk management include risk assessment, mitigation actions, and performance evaluation to continually improve the system. Effective management systems follow a plan-do-check-act cycle. Components of safety in all labs include safe handling of specimens, chemicals, instruments, and waste as well as fire and electrical safety.

1. SAFETY AND BIOSECURITY
Lecture 1:- Introduction of biosafety and security
By:- Dr. Raghda Saad Mohammed

2. Introduction of biosafety and security
 Biosafety refers to “the containment principles,
technologies and practices that are implemented to
prevent unintentional exposure to pathogens and toxins,
or their accidental release.
 Biosecurity refers to measures that are taken to stop the
spread or introduction of harmful organisms to human,
animal and plant life. The measures taken are a
combination of processes and systems that have been
put in place by bioscience laboratories, customs agents
and agricultural managers to prevent the use of
dangerous pathogens and toxins.
 Biorisk:- the risk associated with biological materials in
the laboratory has a safety and a security component.
Biorisk encompasses risks from the biosafety and
laboratory biosecurity perspective , associated with
biological materials.

3. KEY COMPONENTS OF BIORISK MANAGEMENT

4. KEY COMPONENTS OF BIORISK MANAGEMENT
1. Biorisk Assessment: Process of identifying the
hazards and evaluating the risks associated with
biological agents and toxins, taking into account the
adequacy of any existing controls, and deciding whether
or not the risks are acceptable.
2. Biorisk Mitigation: Actions and control measures that
are put into place to reduce or eliminate the risks
associated with biological agents and toxins.
3. Performance: The implementation of the entire biorisk
management system, including evaluating and ensuring
that the system is working the way it was designed.
Another aspect of performance is the process of
continually improving the system.

5. KEY ELEMENT OF EFFECTIVE MANAGEMENT
SYSTEMS
 The concept of continual improvement through a cycle
of planning, implementing, reviewing and improving
processes is undertaken to achieve its goals.
 This is often referred to as the ‘Plan-Do-Check-Act
principle’. The essential elements of each stage are:
A. Plan: including identification of hazard and risk and
establishment of goals;
B. Implement: including training and operational issues;
C. Check: measure/monitor performance against the
objectives; and
D. Act: on the basis of review to make necessary
changes.

6. SYSTEMATIC APPROACH TO BIOSAFETY AND
SECURITY

7. COMPONENTS OF SAFETY IN ALL LABS
 1-Safe handling, storage and disposal of
-Specimens
-Chemicals
-Instruments
-Radioactive components
 2-Fire safety
 3-Electrical safety

8. 1. Consider all the specimens potentially infectious for
HIV and other blood borne infections
2. All specimens should be placed in a leak-proof
impervious container for transport.
3. Use gloves while handling all samples, especially
when there is contact with body fluids, non-intact
skin or mucous membrane.
4. If there is likelihood of spattering, use face mask
with glasses and gowns. Wrap around gowns
should be preferred. These should not be used
outside the lab.
5. Cover cuts or abrasions present over skin with
waterproof bandage.
Universal safety precautions

9. 6. Decontaminate the laboratory work surfaces immediately
in case of spillage of blood or any other body fluids
7. Follow ‘no needle recapping’ strategy
8. All sharps should be collected and disposed away
properly.
9. Never pipette by mouth. Use mechanical pipetting
devices.
10. There should always be a system working efficiently for
management of hospital generated waste.
11. It is advisable for the laboratory personnel to be
vaccinated against Hepatitis-B.
12. Not permitted in Laboratories :Eating, Drinking, Storing
food, Smoking, Handling contact lenses.
Universal safety precautions

10. Thanks for
your
attention
12/10/2021
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