The Renaissance began in Italy in the 14th century as a result of changes brought about by events like the Crusades, Black Death, and Hundred Years' War. Wealthy Italian city-states like Florence financed the Renaissance and patrons like the Medici family in Florence supported artists and scholars. Key intellectual movements included humanism, with its focus on human potential and secularism. Renaissance art flourished in Italy and the Northern Renaissance, with artists like Michelangelo, Leonardo da Vinci, and Durer producing famous works. The Renaissance spread north and its ideas were a precursor to the Protestant Reformation.