This document summarizes several systemic diseases that can manifest in the jaws, including their radiographic features and effects on teeth. Hyperparathyroidism can cause jaw bone demineralization and a "ground glass" trabecular pattern on x-rays. Hypoparathyroidism may show basal ganglia calcification on skull x-rays. Hyperpituitarism can result in jaw enlargement and spacing of teeth. Hypothyroidism can delay dental development and eruption. Cushing's syndrome causes generalized osteoporosis. Osteoporosis may thin the lamina dura on x-rays. Rickets and osteomalacia cause uncalcified osteoid seams and fraying of
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
Phase I periodontal therapy is the first in the chronologic sequence of procedures that constitute periodontal treatment. It is also referred to as cause related therapy or non-surgical periodontal therapy.
This is a presentation describing in brief regarding the physics behind MRI and it's application from dental point of view. It contains few videos as well.
ORN is an inflammatory condition of bone that occurs after the bone has been exposed to therapeutic doses of radiation usually given for a malignancies.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
Phase I periodontal therapy is the first in the chronologic sequence of procedures that constitute periodontal treatment. It is also referred to as cause related therapy or non-surgical periodontal therapy.
This is a presentation describing in brief regarding the physics behind MRI and it's application from dental point of view. It contains few videos as well.
ORN is an inflammatory condition of bone that occurs after the bone has been exposed to therapeutic doses of radiation usually given for a malignancies.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
All the rarefying diseases included here represent a disruption of bone homeostasis that may result from an imbalance among the factors noted or a direct influence of a disese process on the bone itself.
HYPERPARATHYROIDISM
OSTEOPOROSIS
OSTEOMALACIA
LEUKEMIA
LANGERHANS CELL DISEASE
PAGETS DISEASE
MULTIPLE MYELOMA
Systemic Diseases Manifested in the Jawsvahid199212
Systemic Diseases Manifestation the Jaws based on chapter25
Oral Radiology
P R I N C I P L E S
a n d I N T E R P R E T A T I O N Sixth Edition
White and pharoah
This presentation is about Parathyroid Disorders which are hypo and hyperparathyroidism and their relationship to teeth and oral cavity including oral and dental manifestation of these disorders , and correct management patients seeking dental care with these disorders.
developmentally disabled child
downs syndrome
cerebral palsy
introduction
incidence and prevalance
symptoms
precautions to be taken during treatments or during dental treatment or dental checkup
intra oral symptoms which are more commonly seen in these childrens
these children have early or late erruption of teeth
general manifestation of patients with downs syndrome are brachycephelic skull,flat nose bridge
eyes: oblique palpebral fissure , scanty eye lashes
dysplastic ear
shoert neck
congenital heart disease
dudenal atresia
umblical hernia
oral menifestation : such as drooping mouth , open mouth
protusive fissured tongue
dry fissured lips
retarded erruption of teeth
cerebral palsy : classification
spastic cerebral palsy
athetosis
ataxia
rigidity
tremors
atonia
mixed
dental problems : dental caries
periodontal diseases
malocclusion
bruxism
trauma
treatment of these patients
at last conclusion
referance from shobha tandon (pedodontics)
Hormones lect/certified fixed orthodontic courses by Indian dental academyIndian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
GERIATRIC CARE DENTISTRY - ORAL MANIFESTATIONS IN GERIATRIC PATIENTSdrpriyanka8
INTRODUCTION
CLASSIFICATION
AGE CHANGES AFFECTING STRUCTURES IN ORAL CAVITY
COMMON DISEASE AMONG GERIATRIC PATIENTS
MOST COMMON ORAL DISEASE WITH SUGGESTED TREATMENT
GOAL OF ORAL PHYSICIAN
COMMON SYSTEMIC DISEASE IN OLDER ADULT
CONCLUSION
REFERENCES
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/
2. Introduction
▪ More than 99% of the total body calcium is contained within the skeletal structure.
▪ Approximately 5% to 10% of the total bone mass is replaced each year.
▪ The turnover rate of trabecular bone is higher than for cortical bone.
▪ 20% of its mass is replaced per year compared with 5% for cortical bone.
▪ The effects of systemic diseases of bone are brought about by changes in the number and
activity of osteoclasts, osteoblasts, and osteocytes.
▪ Changes to teeth and associated structures include the following:
1. Accelerated or delayed eruption
2. Hypoplasia
3. Hypo-calcification
4. Loss of a distinct lamina dura
3. Radiographic Features
▪ The general changes include the following:
1. A change in size and shape of the bone
2. A change in the number, size, and orientation of trabeculae
3. Altered thickness and density of cortical structures
4. An increase or decrease in overall bone density
▪ Systemic conditions that result in a decrease in bone density do not affect mature
teeth
▪ The image of the teeth may stand out with normal density against a generally
radiolucent jaw.
4.
5.
6. Endocrine Disorders - Hyperparathyroidism
▪ BrownTumor
▪ An excess of circulating parathyroid hormone (PTH).
▪ An excess of serum PTH increases bone remodeling in preference of osteoclastic resorption,
which mobilizes calcium from the skeleton.
▪ PTH increases renal tubular reabsorption of calcium and renal production of the active vitamin D
metabolite
▪ The net result of these functions is in an increase in serum calcium levels.
▪ Primary hyperparathyroidism usually results from a benign tumor (adenoma) of one of the four
parathyroid glands, resulting in the production of excess PTH.
▪ The combination of hypercalcemia and an elevated serum level of PTH is diagnostic of primary
hyperparathyroidism.
▪ The incidence of primary hyperparathyroidism is about 0.1%.
7. Hyperparathyroidism
▪ Secondary Hyperparathyroidism; compensatory increase in the output of PTH in response to
hypocalcemia.
▪ The underlying hypocalcemia may result from an inadequate dietary intake or poor intestinal
absorption of vitamin D or from deficient metabolism of vitamin D in the liver or kidney.
▪ This condition produces clinical and radiographic effects similar to those of primary
hyperparathyroidism.
▪ Women are two to three times more commonly affected than men by primary
hyperparathyroidism.
▪ Most patients have renal calculi, peptic ulcers, psychiatric problems, or bone and joint pain.
Due to Hypercalcemia
▪ Because of daily fluctuations, the serum calcium level should be tested at different intervals
8. Hyperparathyroidism
▪ Only about one in five patients has radiographically observable bone changes.
▪ General Radiographic Features
1. The earliest and most reliable changes of hyperparathyroidism are subtle erosions of
bone from the subperiosteal surfaces of the phalanges of the hands.
2. Demineralization of the skeleton results in an unusual radiolucent appearance.
3. Osteitis fibro-sacystica are localized regions of bone loss
4. Brown tumors occur late in the disease and in about 10% of cases. Radiolucent,
specimen has a brown or reddish-brown color.
5. Pathologic calcifications in soft tissues have a punctate or nodular appearance and occur
in the kidneys and joints.
9. Hyperparathyroidism
▪ 6. In prominent hyperparathyroidism, the entire calvarium has a granular appearance caused
by the loss of central (diploic) trabeculae and thinning of the cortical tables
▪ Radiographic Features of the Jaws;
▪ Demineralization and thinning of cortical boundaries often occur in the jaws in cortical
boundaries.
▪ The density of the jaws is decreased, resulting in a radiolucent appearance that contrasts with
the density of the teeth.
▪ The teeth stand out in contrast to the radiolucent jaws,A change in the normal trabecular
pattern may occur, resulting in a ground-glass appearance of numerous, small, randomly
oriented trabeculae.
10. Hyperparathyroidism
▪ Radiographic Features of theTeeth and Associated Structures.
▪ Occasionally periapical radiographs reveal loss of the lamina dura in patients (only
about 10%) with hyperparathyroidism.
▪ Depending on the duration and severity of the disease, loss of the lamina dura may
occur around one tooth or all the remaining teeth
▪ Management
▪ After successful surgical removal of the causative parathyroid adenoma, almost all
radiographic changes revert to normal.
11.
12.
13.
14. Hyp0parathyroidism and Pseudo-Hypoparathyroidism
▪ Uncommon condition in which insufficient secretion of PTH occurs.
▪ Most common cause is damage or removal of the parathyroid glands during thyroid surgery.
▪ In pseudo-Hypoparathyroidism there is a defect in the response of the tissue target cells to
normal levels of PTH.
▪ Hypocalcemia
▪ Sharp flexion (tetany) of the wrist and ankle joints (carpopedal spasm).
▪ Neurologic and sensory changes may include anxiety and depression, epilepsy,
parkinsonism, and chorea.
▪ Patients with pseudo-hypoparathyroidism often have early closure of certain bony
epiphyses and thus manifest short stature or extremity disproportions.
15. Hypoparathyroidism and Pseudo-
Hypoparathyroidism
▪ Radiographic Features
▪ The principal radiographic change is calcification of the basal ganglia.
▪ On skull radiographs this calcification appears flocculent and paired within the cerebral
hemispheres on the posteroanterior view.
▪ Dental enamel hypoplasia, external root resorption, delayed eruption, or root
dilacerations
▪ Treatment; Orally administered supplemental calcium and vitamin D
16.
17. Hyperpituitarism
▪ Acromegaly and gigantism
▪ Hyperfunction of the anterior lobe of the pituitary gland, which increases the production
of growth hormone.
▪ The usual cause; benign functioning tumor of the acidophilic cells in the anterior lobe
▪ Gigantism; in Children; Generalized overgrowth of most hard and soft tissues, Active
growth occurs in those bones in which the epiphyses have not united with the bone
shafts.
▪ Generalized skeletal growth is excessive and may be prolonged.
▪ Those affected may ultimately attain heights of 7 to 8 feet or more, yet exhibit
remarkably normal proportions.
▪ The eyes and other parts of the central nervous system do not enlarge
18. Hyperpituitarism
▪ Acromegaly;Adults, slow growth because many types of tissues have lost the capacity
for growth.
▪ This is true of much of the skeleton.
▪ Mandibular condylar growth may be very prominent.Also, the supraorbital ridges and
the underlying frontal sinus may be enlarged.
▪ The lips, tongue, nose, and soft tissues of the hands and feet typically overgrow in
adults with acromegaly.
19. Hyperpituitarism
▪ Radiographic Features; General Radiographic Features.
▪ The pituitary tumor often produces enlargement ( “ ballooning ” ) of the Sella turcica.
▪ Skull radiographs characteristically reveal enlargement of the paranasal sinuses (especially
the frontal sinus).
▪ These air sinuses are more prominent in acromegaly than in gigantism because
▪ Diffuse thickening of the outer table of the skull.
20. Hyperpituitarism
▪ Radiographic Features of the Jaws.
▪ Enlargement of the jaws, most notably the mandible and Spacing of the teeth.
▪ Macroglossia + Increased Angle of Mandible = Anterior Open Bite
▪ Hypercementosis
21. Hypopituitarism
▪ Reduced secretion of pituitary hormones.
▪ Dwarfism but have relatively well-proportioned bodies.
▪ One study reported a marked failure of development of the maxilla and the mandible.
▪ The dimensions of these bones in adults with this disorder were approximately those of
normal children 5 to 7 years of age.
▪ Radiographic Features
▪ Eruption of the primary dentition occurs at the normal time, but exfoliation is delayed by
several years.
▪ The crowns of the permanent teeth form normally, but their eruption is delayed several
years.
▪ Crowding,AbsentWisdom buds
23. Hyperthyroidism
▪ Thyrotoxicosis and Graves’ disease
▪ Excessive production of thyroxin hormone.
▪ Most commonly with diffuse toxic goiter (Graves ’ disease) and less frequently with toxic
nodular goiter or toxic adenoma.
▪ thyroxine causes a generalized increase in the metabolic rate of all body tissues, resulting
in tachycardia, increased blood pressure, sensitivity to heat, and irritability.
▪ More common in females.
▪ Radiographic Features
▪ Advanced rate of dental development and early eruption, with premature loss of the
primary teeth.
24. Hyperthyroidism
▪ Adults may show a generalized decrease in bone density or loss of some areas of edentulous
alveolar bone.
25. Hypothyroidism
▪ Myxedema and cretinism
▪ Insufficient secretion of thyroxine
▪ In children, hypothyroidism may result in retarded mental and physical development.The
base of the skull shows delayed ossification, and the paranasal sinuses only partially
pneumatize.
▪ Dental development is delayed, and the primary teeth are slow to exfoliate.
▪ Hypothyroidism in the adult results in myxedematous swelling but not the dental or skeletal
changes seen in children.
▪ Adult symptoms may range from lethargy, poor memory, inability to concentrate,
constipation, and cold intolerance to the more florid clinical picture of dull and
expressionless face, periorbital edema, large tongue, sparse hair, and skin that feels
“doughy” to the touch.
26. Hypothyroidism
▪ Radiographic Features
▪ Delayed closing of the epiphyses and skull sutures with the production of numerous
wormian bones (accessory bones in the sutures).
▪ Effects on the teeth include delayed eruption, short roots, and thinning of the
lamina dura.
▪ The maxilla and mandible are relatively small.
▪ Adult; periodontal disease, loss of teeth, separation of teeth as a result of enlargement
of the tongue, and external root resorption.
27. Diabetes Mellitus
▪ Type I
▪ Type II
▪ Gestational
▪ Polyphagia, Polydipsia and Polyuria
▪ Recently diabetes has been documented as a risk factor in the development of
bisphosphonate-related osteonecrosis.
▪ Radiographic Features
▪ No characteristic radiographic features of the jaws or teeth.
▪ Periodontal disease associated with diabetes is indistinguishable radiographically from
periodontal disease in patients without diabetes.
28. Cushing’s Syndrome
▪ Excess of secretion of glucocorticoids by the adrenal glands.
▪ May result from:
1. An adrenal adenoma
2. An adrenal carcinoma
3. Adrenal hyperplasia (usually bilateral)
4. A basophilic adenoma of the anterior lobe of the pituitary gland (Cushing ’ s disease),
producing excess adrenocorticotropic hormone
5. Medical therapy with exogenous corticosteroids
▪ The increased level of glucocorticoid results in a loss of bone mass from reduced
osteoblastic function and either directly or indirectly increased osteoclastic function.
29. Cushing’s Syndrome
▪ Obesity (which spares the extremities),
▪ Kyphosis of the thoracic spine ( “Buffalo hump” )
▪ Weakness, hypertension, striae, or concurrent diabetes.
▪ Females three to five times as frequently as males, 2nd decade.
▪ Radiographic Features
▪ Generalized osteoporosis, which may have a granular bone pattern.
▪ Pathologic fractures.
▪ The skull can show diffuse thinning accompanied by a mottled appearance.
▪ The teeth may erupt prematurely, and partial loss of the lamina dura may occur
30.
31. Osteoporosis
▪ A generalized decrease in bone mass in which the histologic appearance of bone is normal.
▪ An imbalance in bone resorption and formation.
▪ Decrease in bone formation results in changes in trabecular architecture, the volume of trabecular
bone, and the size and thickness of individual trabeculae.
▪ Primary Osteoporosis occurs with the aging process of bone and can be considered a variation of
normal.
▪ At 30 years of age there begins a gradual and progressive decline of about 8% per decade in
women and 3% per decade in men.
▪ Secondary Osteoporosis may result from nutritional deficiencies, hormonal imbalance, inactivity,
or corticosteroid or heparin therapy
32. Osteoporosis
▪ The most important clinical manifestation of osteoporosis is fracture.
▪ The most common locations are the distal radius, proximal femur, ribs, and vertebrae.
▪ The population most at risk is postmenopausal women.
▪ Radiographic Features; overall reduction in the density of bone.
▪ This reduction may be observed in the jaws by using the unaltered density of teeth as a
comparison.
▪ On occasion the lamina dura may appear thinner than normal.
▪ In other regions of the mandible a reduction in the number of trabeculae may be evident.
▪ Dual-energy photon absorption or quantitative computed tomography programs.
33. Osteoporosis
▪ Treatment
▪ The administration of estrogens and calcium and vitamin D supplements after
menopause helps to reduce the rate of cortical and trabecular bone loss.
▪ Weight-bearing exercise programs are also effective (not swimming, for instance).
34. Rickets and Osteomalacia
▪ Result from inadequate serum and extracellular levels of calcium and phosphate.
▪ Both abnormalities result from a defect in the normal activity of the metabolites of
vitamin D required for resorption of calcium in the intestine.
▪ Failure of normal mineralization is seen histologically as wide uncalcified osteoid (new
bone matrix) seams.
▪ Rickets; when the disease affects the growing skeleton in infants and children.
▪ Osteomalacia; when this disease affects the mature skeleton in adults.
35. Rickets and Osteomalacia
▪ Failure of normal activity of vitamin D may occur as a result of the following:
1. Lack of vitamin D in the diet
2. Lack of absorption of vitamin D resulting from various gastrointestinal malabsorption
problems
3. Lack of metabolism of the active metabolite 1,25(OH) 2 D, which is required for intestinal
absorption of calcium
▪ Rickets. In the first 6 months of life, tetany or convulsions are the most common clinical
problems resulting from the hypocalcemia of rickets. Later the skeletal effects may be more
clinically prominent.
▪ Craniotabes, a softening of the posterior of the parietal bones, may be the initial sign of the
disease.The wrists and
36. Rickets and Osteomalacia
▪ Osteomalacia.
▪ Most patients with osteomalacia have some degree of bone pain.
▪ The majority of patients with osteomalacia have muscle weakness of varying severity.
▪ Other clinical features include a peculiar waddling or “penguin” gait, tetany, and
greenstick bone fractures.
37. Rickets and Osteomalacia
▪ Radiographic Features
▪ General Radiographic Features;
▪ Rickets; the earliest and most prominent radiographic manifestation is a widening and
fraying of the epiphyses of the long bones.
▪ The soft weight-bearing bones such as the femur and tibia undergo a characteristic bowing.
▪ Osteomalacia; the cortex of bone may be thin.
▪ Pseudo-fractures, which are poorly calcified ribbon-like zones occur most commonly in the
ribs, pelvis, and weight-bearing bones and rarely in the mandible.
38. Rickets and Osteomalacia
▪ Radiographic Features of the Jaws.
▪ Rickets; jaw cortical structures such as the inferior mandibular border or the walls of the
mandibular canal may thin.
▪ Changes in the jaws generally occur after changes in the ribs and long bones.
▪ Within the cancellous portion of the jaws, the trabeculae become reduced in density, number,
and thickness.
▪ The jaws appear so radiolucent that the teeth appear to be bereft of bony support.
▪ Most cases of osteomalacia produce no radiographic manifestations in the jaws.
▪ Hypoplasia of Developing Dental Enamel
39.
40. Hypophosphatasia
▪ Rare inherited disorder that is caused by either a reduced production or a defective function of
alkaline phosphatase.
▪ Patients have a low level of serum alkaline phosphatase activity and elevated urinary excretion of
phosphor-ethanolamine.
▪ AD but AR patterns are not uncommon
▪ Homozygous involvement usually begins in utero, and affected patients often die within the first
year, bowed limb bones and a marked deficiency of skull ossification.
▪ Heterozygous involvement; biochemical defects but a milder disease clinically, poor growth,
fractures, and deformities similar to rickets.
▪ A history may exist of fractures, delayed walking, or rickets-like deformities that heal
spontaneously.
▪ About 85% of these children show premature loss of the primary teeth, particularly the incisors,
and delayed eruption of the permanent dentition.
41. Hypophosphatasia
▪ Radiographic Features; General Radiographic Features.
▪ In young children; the long bones show irregular defects in the epiphysis, and the skull is
poorly calcified.
▪ In older children with premature closure of the skull sutures, multiple lucent areas of the
calvarium may exist, called gyral or convolutional markings [hammered copper].
▪ The skull may assume a brachycephalic shape.
▪ A generalized reduction in bone density may occur in adults.
▪ Radiographic Features of the Jaws.
▪ A generalized radiolucency of the mandible and maxilla is evident.
▪ Thin Enamel, Large Pulp chambers and RootCanals, Hypoplastic and premature loss
42.
43. Renal Osteodystrophy - Rickets
▪ The clinical features of renal osteodystrophy are those of chronic renal failure.
▪ In children, growth retardation and frequent bone fractures may occur.
▪ Adults may have a gradual softening and bowing of the bones.
▪ Hypoplasia and hypo-calcification of the teeth are possible, sometimes resulting in
loss of any radiographic evidence of enamel.
44.
45. Hypophosphatemia
▪ Radiographic Features Associated with theTeeth.
▪ Thin enamel caps and large pulp chambers and root canals.
▪ In addition, periapical and periodontal abscesses occur frequently.
46. Osteopetrosis
▪ Albers-Schönberg and marble bone disease
▪ Disorder of bone that results from a defect in the differentiation and function of osteoclasts.
▪ Generalized increase in bone mass.
▪ The failure of normal bone remodeling results in dense, fragile bones that are susceptible to
fracture and infection.
▪ Obliteration of the marrow compromises hematopoiesis and compresses cranial nerves.
▪ Autosomal recessive type - Osteopetrosis congenita
▪ Autosomal dominant type - Osteopetrosis tarda
47. Osteopetrosis
▪ Clinical Features
▪ The more severe, recessive form of osteopetrosis is seen in infants and young children, and
the more benign, dominant form appears later.
▪ The severe form is invariably fatal early in life
▪ The narrowing of bony canals results in hydrocephalus, blindness, deafness, vestibular
nerve dysfunction, and facial nerve paralysis.
▪ Osteomyelitis may complicate this disease because of the relative lack of vascularity of the
dense bone.
▪ This problem is more common in the mandible, whereas osteomyelitis is usually a result of
dental or periodontal disease.
48. Osteopetrosis
▪ Radiographic Features of the Jaws.
▪ The increased Radiopacity of the jaws may be so great that the radiographic image may fail to
reveal any internal structure and even the roots of the teeth may not be apparent.
▪ Radiographic Features Associated with theTeeth.
▪ Effects on teeth may include delayed eruption, early tooth loss, missing teeth, malformed roots
and crowns, and teeth that are poorly calcified and prone to caries.
▪ Differential Diagnosis; Sclerosing bone dysplasia,Osteosclerosis and Secondary
Hyperparathyroidism
▪ Treatment; Bone MarrowTransplant
49.
50. Systemic Sclerosis
▪ Scleroderma
▪ Generalized connective tissue disease that causes excessive collagen deposition
resulting in hardening (sclerosis) of the skin and other tissues.
▪ The involvement of the gastrointestinal tract, heart, lungs, and kidneys usually results
in more serious complications.
▪ PSS is a disease of middle age,Women are affected about three times as often as men.
▪ Xerostomia; increased numbers of decayed, missing, or filled teeth; and carious
lesions.
51. Systemic Sclerosis
▪ Radiographic Features; Radiographic Features of theJaws.
▪ Unusual pattern of mandibular erosions at regions of muscle attachment such as the
angles, coronoid process, digastric region, or condyles.
▪ This type of resorption is typically bilateral and fairly symmetric.
▪ Most of these erosive borders are smooth and sharply defined.
▪ Radiographic Changes Associated with theTeeth; increase in width of the periodontal
ligament (PDL) spaces around the teeth
▪ Differential Diagnosis
▪ Management; Not required usually
52.
53. Sickle Cell Anemia
▪ Autosomal recessive, chronic hemolytic blood disorder.
▪ Abnormal hemoglobin which under low oxygen tension results in sickling of the red blood cells.
▪ The spleen traps and readily destroys these abnormal red blood cells.
▪ The hematopoietic system responds to the resultant anemia by increasing the production of
red blood cells, which requires compensatory hyperplasia of the bone marrow.
▪ Gene in heterozygous state in about 6% to 8% of African-Americans, those who manifest this
form of the sickle cell trait do not show related clinical findings.
▪ During the crisis state, patients often have severe abdominal, muscle, and joint pain and a high
temperature and may even undergo circulatory collapse.
54. Sickle Cell Anemia
▪ During milder periods the patient may complain of fatigability, weakness, shortness of
breath, and muscle and joint pain.
▪ As in the other chronic anemias, the heart is usually enlarged and a murmur may be
present.
▪ The disease occurs mostly in children and adolescents.
▪ It is compatible with a normal life span, although many patients die of complications of
the disease before the age of 40 years.
55. Sickle CellAnemia
▪ General Radiographic Features.
▪ The thinning of individual cancellous trabeculae and cortices is most common in the vertebral
bodies, long bones, skull, and jaws.The skull may have widening of the diploic space and
thinning of the inner and outer tables
▪ In extreme cases (5%) the outer table of the skull will not be apparent and a hair-on-end
appearance may occur.
▪ Small areas of infarction may be present within bones after blockage of the microvasculature;
these are seen radiographically as areas of localized bone sclerosis.
▪ Osteomyelitis may complicate sickle cell anemia
▪ Jaws; General Osteoporosis
58. Thalassemia
▪ Hereditary disorder that results in a defect in hemoglobin synthesis.
▪ The heterozygous form of the disease (thalassemia minor) is mild.
▪ The homozygous form (thalassemia major) may be severe.
▪ A less severe form, thalassemia intermedia, also occurs.
▪ The onset is in infancy and the survival time may be short.
▪ The face develops prominent cheekbones and a protrusive premaxilla, resulting in a “rodent-
like” face.
59. Thalassemia
▪ Radiographic Features
▪ General Radiographic Features; There is a generalized radiolucency of the long bones with
cortical thinning.
▪ In the skull the diploic space exhibits marked thickening, especially in the frontal region.
The
▪ skull shows a generalized granular appearance and occasionally a hair-on-end effect may
develop.
▪ Radiographic Appearance of the Jaws. Severe bone marrow hyperplasia prevents
pneumatization of the paranasal sinuses, especially the maxillary sinus
▪ The jaws appear radiolucent