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PROTEOME  HARIS & ARUN MSC BIOTECHNOLOGY MAC & AL-AZHAR ERNAKULAM
Introduction ,[object Object],[object Object],[object Object],[object Object]
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[object Object],[object Object]
PROTEOMICS ,[object Object],[object Object],[object Object]
[object Object],MS driven techniques •  MS identification of proteins after quantitative  analysis by 2DE –  Peptide mass fingerprinting (Maldi MS) –  Sequence based identification (MS/MS)
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Tryptic peptides co-crystallized with matrix compound on sample stage • Irradiation with UV-laser • Matrix compound vaporized and included peptide ions moved to gas phase • Protonated peptide ions
APPLICATIONS Application of Proteomics in the Study of Tumor Metastasis. ,[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
New drugs for treatment of disease ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
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Proteome

  • 1. PROTEOME HARIS & ARUN MSC BIOTECHNOLOGY MAC & AL-AZHAR ERNAKULAM
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  • 8. Tryptic peptides co-crystallized with matrix compound on sample stage • Irradiation with UV-laser • Matrix compound vaporized and included peptide ions moved to gas phase • Protonated peptide ions
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