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Pennington Nutrition Series
Healthier lives through education in nutrition and preventive medicine                                          Pub No 51




                                         PROBIOTICS
                                              PENNINGTON             BIOMEDICAL   RESEARCH    CENTER




                                              WHAT        ARE       PROBIOTICS?
         SPECIAL
         POINTS OF
         INTEREST:
                                              Probiotics are living micro-organisms or bacteria that we consume
            What are Probiotics?
                                              in foods or beverages. Probiotic bacteria are friendly bacteria that
            Types of Probiotic
            bacteria                          live in our bodies and offer many benefits. There are many different
            Intestinal microflora             varieties of friendly bacteria that exist naturally in foods or drinks, or
            Functions of                      can be added to foods or beverages to enhance health and well
            probiotics
                                              being. When friendly bacteria are added into foods or beverages
            Improved immunity
            through probiotics                they are known as functional foods.
            Probiotics and
                                              Probiotic bacteria are also available in
            intestinal health
                                              supplement form. Most supplements
            Other health
            conditions                        contain mixtures of several bacteria.
            Sources of probiotics             Supplements and foods high in probiotic
                                              bacteria may be useful after antibiotic
                                              therapy to re-colonize the intestinal
                                              track with healthy bacteria.
                                                                                                Yogurt has friendly
                                                                                                probiotic bacteria.




                                              TYPES         OF     PROBIOTIC      BACTERIA



                                              Some of the most common types of probiotic bacteria are the
                                              Lactic acid bacteria. These bacteria are found in yogurt.
                                              Lactobacillus acidophilus, Lactobacillus bulgaricus and
                                              Streptococcus thermophilus are some common bacteria in
                                              different varieties of yogurt. Other bacteria that are used as
                                              probiotics are non-lactic acid bacteria and non-pathogenic yeast.
PROBIOTICS                                                                       Page 2




                            INTESTINAL             MICROFLORA

                            The intestines are a         We have many                    where the conditions
                            unique and vital organ.      organisms that live             are very acidic, there
                            The intestines are           within our intestinal           are living bacteria. Nor-
                            metabolically very           track to assure a               mal microflora can be
                            active. During and after     normal health. The              enhanced by ingesting
                            a meal, digestion and        weight of all the bacte-        products that have
                            absorption break down        ria within our                  friendly bacteria, or
                            the food with a myriad       intestines is about 1.5         substances that sup-
                            of reactions happening       kg, or a little over 3          port bacterial growth.
                            simultaneously to take       pounds, with a total            Under normal condi-
                            care of our energy and       over 100 trillion. Each         tions, the bacteria
                            nutrient needs, as well      section of the intestinal       thrive, but they can be
                            as letting our brains        track has specific bac-         killed by antibiotic
                            know that we have            teria that live in it. Even     therapy.
                            eaten.                       within the stomach,


                            FUNCTIONS           OF      PROBIOTICS
  Probiotic bacteria        Probiotics have been         treatment for various           treatment for
  offer protection                                                                       rheumatoid arthritis.
                            used for various             intestinal conditions
  against harmful
                            conditions. They have        such as lactose                 Other conditions that
  bacteria and
                            been found to modulate       intolerance, Crohn's            have improved due to
  enhance our
                            immunity, particularly in    disease, ulcerative             probiotic treatment are
  immune system.
                            infants. The presence of     colitis, Irritable Bowel        atopic dermatitis,
                            the friendly bacteria in     Syndrome (IBS),                 candidiasis and urinary
                            the intestinal track         diarrhea, and                   tract infections.
                            activates the immune         constipation.                   Probiotics are also
                            system and boosts            Probiotics have been            thought to be helpful in
                            important immune             successful in lowering          preventing cancer, par-
                            components. They are         cholesterol. They have          ticularly intestinal
                            important as a               also been used as a             cancers.


                            IMPROVED          IMMUNITY           THROUGH               PROBIOTICS

                            About 80 percent of our      tion against invasive           either build tolerance
                            immune system func-          species. The GALT has           against antigens or
                            tion is within the           cells such as T and B           alter cell chemistry and
                            intestinal track. Within     lymphocytes that                its response to an
                            the intestinal track we      actively defend us              allergen. The friendly
                            have what is called gut      against pathogens. The          bacteria help reduce
Lymphocytes are important   associated lymphoid          beneficial bacteria             inflammation and
cells for helping our       tissue or GALT. GALT is      activate these                  stabilize the intestinal
immune system cope with     very important when it       lymphocytes and cause           track.
infection.                  comes to body                a release of several
                            immunity and protec-         cellular chemicals that
Page 3                                                              PUB    NO   51




PROBIOTICS              AND    INTESTINAL                HEALTH

Probiotics have been          probiotic bacteria as        with probiotic treatment
used to treat several         part of the treatment        are Crohn's disease,
intestinal conditions. It     can reduce the severity      ulcerative colitis, IBS
is thought that when          and length of the bouts      and constipation. The
the intestinal track is       and can help the infant      probiotic bacteria
colonized with healthy        recover faster. The          normalize the walls of
and friendly bacteria,        same is true for             the intestinal tract and
the gut is healthier and      traveler’s diarrhea.         help in the healing
therefore it functions        Studies show that there      process. Probiotics are      Probiotic bacteria
better. Pediatric             is a reduction in days       also responsible for
diarrhea is a very            affected by traveler’s       synthesizing nutrients in
common occurrence             diarrhea when probiotic      the intestinal tract such
and can have serious          treatment is                 as folic acid, niacin,
effects such as               administered. Other          riboflavin, vitamins B6
dehydration. Using            conditions improved          and B12.


OTHER        HEALTH          CONDITIONS

The probiotic bacteria        Probiotic bacteria help      is multifaceted and very    Probiotic bacteria
have many functions           in enhancing the             difficult to treat and          have varied
and they are very me-         immune system and for        there is no one solution.   functions and help
tabolically active. In        that reason is thought       One of the facets of the       against many
young infants they offer      to offer help in             disorder is intestinal          conditions.
help with intestinal tract    conditions such as           malfunction which can
maturation. They also         rheumatoid arthritis         be augmented by
contribute to enhanced        and atopic dermatitis.       treatment with probiotic
immunity in the young         Probiotics have also         bacteria.
infant. Probiotics can        been found to benefit
also help with skin           children that have
disorders such as             autism spectrum
atopic eczema.                disorders. The disorder


SOURCES          OF     PROBIOTICS

The most common               makes the product            bacteria. Other foods
sources of friendly           sour. Some cultured          that that are either
bacteria are yogurt,          cheeses use bacteria to      produced by bacterial
cultured buttermilk, and      finish the maturation of     fermentation, or
cheeses. Make sure            the cheese. Another          process are Japanese
that the yogurt               fermented dairy product      Miso, Tempeh,
packaging states ‘live        is kefir. Traditionally      sauerkraut, beer,
bacteria.’ Cultured           yogurt has only one or       sourdough bread,            Many aged cheeses
                                                                                       are fermented
buttermilk is made with       two bacteria whereas         chocolate, kimchi,
                                                                                       products and contain
bacteria that produces        kefir tends to have          olives, and pickles.        friendly bacteria .
lactic acid, which            several friendly
The Pennington Nutrition Series Fact sheets have the
                                            latest nutrition information on various health topics
                                            from dietary guidelines to functional foods.




                                             The Pennington Biomedical Research Center is a
                                                world renowned nutrition research center.
   PENNINGTON BIOMEDICAL
   RESEARCH CENTER
                                            The Pennington Biomedical Research Center is a world-
   6400 Perkins Road                        renowned nutrition research center.
   Baton Rouge, LA 70808

                                            Mission:
   Phone: 225-763-2500                      To promote healthier lives through research and education in
   www.pbrc.edu                             nutrition and preventive medicine.

                                            The Pennington Center has several research areas, including:

                                                Clinical Obesity Research
               Visit our Web Site               Experimental Obesity
                 www.pbrc.edu                   Functional Foods
                                                Health and Performance Enhancement
                                                Nutrition and Chronic Diseases
                                                Nutrition and the Brain
                References                      Dementia, Alzheimer’s and healthy aging
Symposium: Clinical Applications of             Diet, exercise, weight loss and weight loss maintenance
Probiotics in Human Health. September 14-
15, 2007, Las Vegas, Nevada.                The research fostered in these areas can have a profound im-
                                            pact on healthy living and on the prevention of common
                                            chronic diseases, such as heart disease, cancer, diabetes, hy-
Pennington Nutrition Series No 51, 2009     pertension and osteoporosis.
Authors
                                            The Division of Education provides education and informa-
                                            tion to the scientific community and the public about research
Heli J. Roy, PhD, RD                        findings, training programs and research areas, and coordi-
Beth Kalicki                                nates educational events for the public on various health is-
                                            sues.

Division of Education                       We invite people of all ages and backgrounds to participate in
                                            the exciting research studies being conducted at the Penning-
Phillip Brantley, PhD, Director
                                            ton Center in Baton Rouge, Louisiana. If you would like to
Pennington Biomedical Research Center       take part, visit the clinical trials web page at www.pbrc.edu or
Claude Bouchard, PhD, Executive Director    call (225) 763-3000.

Edited : October 2009

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Probiotics are good for you

  • 1. Pennington Nutrition Series Healthier lives through education in nutrition and preventive medicine Pub No 51 PROBIOTICS PENNINGTON BIOMEDICAL RESEARCH CENTER WHAT ARE PROBIOTICS? SPECIAL POINTS OF INTEREST: Probiotics are living micro-organisms or bacteria that we consume What are Probiotics? in foods or beverages. Probiotic bacteria are friendly bacteria that Types of Probiotic bacteria live in our bodies and offer many benefits. There are many different Intestinal microflora varieties of friendly bacteria that exist naturally in foods or drinks, or Functions of can be added to foods or beverages to enhance health and well probiotics being. When friendly bacteria are added into foods or beverages Improved immunity through probiotics they are known as functional foods. Probiotics and Probiotic bacteria are also available in intestinal health supplement form. Most supplements Other health conditions contain mixtures of several bacteria. Sources of probiotics Supplements and foods high in probiotic bacteria may be useful after antibiotic therapy to re-colonize the intestinal track with healthy bacteria. Yogurt has friendly probiotic bacteria. TYPES OF PROBIOTIC BACTERIA Some of the most common types of probiotic bacteria are the Lactic acid bacteria. These bacteria are found in yogurt. Lactobacillus acidophilus, Lactobacillus bulgaricus and Streptococcus thermophilus are some common bacteria in different varieties of yogurt. Other bacteria that are used as probiotics are non-lactic acid bacteria and non-pathogenic yeast.
  • 2. PROBIOTICS Page 2 INTESTINAL MICROFLORA The intestines are a We have many where the conditions unique and vital organ. organisms that live are very acidic, there The intestines are within our intestinal are living bacteria. Nor- metabolically very track to assure a mal microflora can be active. During and after normal health. The enhanced by ingesting a meal, digestion and weight of all the bacte- products that have absorption break down ria within our friendly bacteria, or the food with a myriad intestines is about 1.5 substances that sup- of reactions happening kg, or a little over 3 port bacterial growth. simultaneously to take pounds, with a total Under normal condi- care of our energy and over 100 trillion. Each tions, the bacteria nutrient needs, as well section of the intestinal thrive, but they can be as letting our brains track has specific bac- killed by antibiotic know that we have teria that live in it. Even therapy. eaten. within the stomach, FUNCTIONS OF PROBIOTICS Probiotic bacteria Probiotics have been treatment for various treatment for offer protection rheumatoid arthritis. used for various intestinal conditions against harmful conditions. They have such as lactose Other conditions that bacteria and been found to modulate intolerance, Crohn's have improved due to enhance our immunity, particularly in disease, ulcerative probiotic treatment are immune system. infants. The presence of colitis, Irritable Bowel atopic dermatitis, the friendly bacteria in Syndrome (IBS), candidiasis and urinary the intestinal track diarrhea, and tract infections. activates the immune constipation. Probiotics are also system and boosts Probiotics have been thought to be helpful in important immune successful in lowering preventing cancer, par- components. They are cholesterol. They have ticularly intestinal important as a also been used as a cancers. IMPROVED IMMUNITY THROUGH PROBIOTICS About 80 percent of our tion against invasive either build tolerance immune system func- species. The GALT has against antigens or tion is within the cells such as T and B alter cell chemistry and intestinal track. Within lymphocytes that its response to an the intestinal track we actively defend us allergen. The friendly have what is called gut against pathogens. The bacteria help reduce Lymphocytes are important associated lymphoid beneficial bacteria inflammation and cells for helping our tissue or GALT. GALT is activate these stabilize the intestinal immune system cope with very important when it lymphocytes and cause track. infection. comes to body a release of several immunity and protec- cellular chemicals that
  • 3. Page 3 PUB NO 51 PROBIOTICS AND INTESTINAL HEALTH Probiotics have been probiotic bacteria as with probiotic treatment used to treat several part of the treatment are Crohn's disease, intestinal conditions. It can reduce the severity ulcerative colitis, IBS is thought that when and length of the bouts and constipation. The the intestinal track is and can help the infant probiotic bacteria colonized with healthy recover faster. The normalize the walls of and friendly bacteria, same is true for the intestinal tract and the gut is healthier and traveler’s diarrhea. help in the healing therefore it functions Studies show that there process. Probiotics are Probiotic bacteria better. Pediatric is a reduction in days also responsible for diarrhea is a very affected by traveler’s synthesizing nutrients in common occurrence diarrhea when probiotic the intestinal tract such and can have serious treatment is as folic acid, niacin, effects such as administered. Other riboflavin, vitamins B6 dehydration. Using conditions improved and B12. OTHER HEALTH CONDITIONS The probiotic bacteria Probiotic bacteria help is multifaceted and very Probiotic bacteria have many functions in enhancing the difficult to treat and have varied and they are very me- immune system and for there is no one solution. functions and help tabolically active. In that reason is thought One of the facets of the against many young infants they offer to offer help in disorder is intestinal conditions. help with intestinal tract conditions such as malfunction which can maturation. They also rheumatoid arthritis be augmented by contribute to enhanced and atopic dermatitis. treatment with probiotic immunity in the young Probiotics have also bacteria. infant. Probiotics can been found to benefit also help with skin children that have disorders such as autism spectrum atopic eczema. disorders. The disorder SOURCES OF PROBIOTICS The most common makes the product bacteria. Other foods sources of friendly sour. Some cultured that that are either bacteria are yogurt, cheeses use bacteria to produced by bacterial cultured buttermilk, and finish the maturation of fermentation, or cheeses. Make sure the cheese. Another process are Japanese that the yogurt fermented dairy product Miso, Tempeh, packaging states ‘live is kefir. Traditionally sauerkraut, beer, bacteria.’ Cultured yogurt has only one or sourdough bread, Many aged cheeses are fermented buttermilk is made with two bacteria whereas chocolate, kimchi, products and contain bacteria that produces kefir tends to have olives, and pickles. friendly bacteria . lactic acid, which several friendly
  • 4. The Pennington Nutrition Series Fact sheets have the latest nutrition information on various health topics from dietary guidelines to functional foods. The Pennington Biomedical Research Center is a world renowned nutrition research center. PENNINGTON BIOMEDICAL RESEARCH CENTER The Pennington Biomedical Research Center is a world- 6400 Perkins Road renowned nutrition research center. Baton Rouge, LA 70808 Mission: Phone: 225-763-2500 To promote healthier lives through research and education in www.pbrc.edu nutrition and preventive medicine. The Pennington Center has several research areas, including: Clinical Obesity Research Visit our Web Site Experimental Obesity www.pbrc.edu Functional Foods Health and Performance Enhancement Nutrition and Chronic Diseases Nutrition and the Brain References Dementia, Alzheimer’s and healthy aging Symposium: Clinical Applications of Diet, exercise, weight loss and weight loss maintenance Probiotics in Human Health. September 14- 15, 2007, Las Vegas, Nevada. The research fostered in these areas can have a profound im- pact on healthy living and on the prevention of common chronic diseases, such as heart disease, cancer, diabetes, hy- Pennington Nutrition Series No 51, 2009 pertension and osteoporosis. Authors The Division of Education provides education and informa- tion to the scientific community and the public about research Heli J. Roy, PhD, RD findings, training programs and research areas, and coordi- Beth Kalicki nates educational events for the public on various health is- sues. Division of Education We invite people of all ages and backgrounds to participate in the exciting research studies being conducted at the Penning- Phillip Brantley, PhD, Director ton Center in Baton Rouge, Louisiana. If you would like to Pennington Biomedical Research Center take part, visit the clinical trials web page at www.pbrc.edu or Claude Bouchard, PhD, Executive Director call (225) 763-3000. Edited : October 2009