This document discusses prescription auditing as a way to promote rational drug use and improve patient care. It defines rational drug use as using the right drug, at the right dosage and cost to meet a patient's clinical needs. Prescription auditing involves collecting data on current prescribing practices and comparing it to standards to identify areas for improvement. The audit cycle involves defining standards, collecting data, identifying issues, implementing changes, and defining new standards. Prescription audits can help ensure appropriate drug therapy, control costs, prevent medication problems, evaluate effectiveness, and identify needs for practitioner education.