- Complete an application to become a member physician and set up your practice profile - Attend online training for your staff on insurance billing, inventory management, and using the dispensing software - Begin offering FDA-approved pharmacogenetic test kits and pre-filled injection kits to patients using point-of-care billing - The company handles insurance credentialing and adjudication of claims, minimizing practice expenses and workload - With 10% patient penetration, the average practice could earn over $369,000 annually from kit dispensing and testing

1. May We Get to Know You?
 How many patients do you see a day on average?
 Are you currently utilizing pharmacogenomics testing?
 Are you or have you ever dispensed Rx in your practice?
 How familiar are you with NDC codes associated with
prescriptions?

2. Navigating Healthcare’s Changing Landscape
Physicians are looking for ways to practice precision medicine
that meet the following criteria:
 Improves Patient Outcomes
 Supports the Practice Income Objectives
 Custom Cutting Edge Science
 Risk Mitigation
 Turn-key Practice Solutions
 Includes Consulting & Support
 Leading Science
 Excellent Practice Support
 Proven Track Record
 Optimum Service
 Licensed & Insured
 Credentials & Regulation Compliant
We Evaluate Providers To Ensure:

3. Why Physicians Choose Biotech Medical Solutions
Dispensing for an Average Practice
There are many options available for your patients and your practice
In-Office Dispensing
 PBSO – Pharmacy Benefit
Services
 Phamacogenetics Kit
 Toxicology Kit
 Injectables
 Medicated Kits
 Medical Foods
Other Services
 Compounding Pharmacy Services
 HIPAA & ICD-10 Training
 Patient Education Materials
 Physician & Staff Telephone Support
Our unique offering includes our 1st to market NDC-coded
medicated kits.
1st To Market

4. Benefits of Dispensing to Patients
Patient Compliance and Care Monitoring
• Studies have estimated that 30-40% of prescribed medications go unfilled
• In-office dispensing respects patients’ time and will increase patient compliance
with medication regimens
Safety and Accuracy
• 6-8% percent of patients who receive medication from a pharmacy receive
incorrect dosages or drugs
• State regulatory boards have imposed harder restrictions for in-office dispensing
which has resulted in a reduction of error rates in comparison to filling medication
at a retail pharmacy
By implementing in-office dispensary you will be able to monitor a patient’s treatment
and prescription compliance, allowing for a higher level of safety and accuracy.
In the USA all 50 states have regulations governing physician dispensing, 46 states
allow physicians to participate in the profit from their practices that includes
dispensing pharmaceuticals.

5. Pharmacy Benefits Service Organization (PBSO)
Full Service Dispensing Partner - What Sets Us Apart
 Completion and Submission of all Credentialing
 Third-Party Payor Enrollments
 Real Time In-Office Eligibility Verification
 Pharmacy Billing Management
 Insurance, Cash, and Workers’ Comp Claim Adjudications
 Inventory Management
 Live Customer Service and On-Site Support Training
 24 Hour Access to Dispensing Reports
- Patient Fulfillment
- Accounting
- Inventory

6. The Case For Pharmacogenetic Testing
Adverse Drug Reactions are the
4TH LEADING
CAUSE OF DEATH
ahead of pulmonary disease, diabetes,
AIDS, and automobile deaths
Every year, more than 8.6 million adverse drug events
(ADRs) are reported in the US — 2.2 million of them are
severe.
In fact, ADRs are the fourth leading cause of death
nationwide, after heart disease, cancer and stroke, and
they place an enormous financial burden on the
healthcare system.

7. Pharmacogenetic testing provides insight into the four major “trial and error”
factors physicians have to battle with every prescription.
 Which drug will work best for the patient?
 How much does the patient need?
 How will it interact with other substances?
 Will it be likely to cause an adverse event or reaction?
Drug Metabolism, Interaction & Adverse Reactions

8. Preventing Adverse Drug Reactions
Even with proper prescribing, a
patient’s genetics can affect how they
metabolize and respond to drugs.
More than 85% of patients have
detectable variations in their DNA that
increase their risk for an ADR.
Pharmacogenetic testing determines a patient’s drug metabolizing capacity and physicians
are able to quickly find the safest, most effective drug and dose for each patient’s unique
genetics

9. How does pharmacogenetic testing alter the treatment course and patient response for
chronic-pain patients in comparison with the current "trial-and-error" standard of care?
J Am Assoc Nurse Pract. 2014 Oct;26(10):530-6. doi: 10.1002/2327-6924.12154. Epub 2014 Aug 7.
DeFeo K1, Sykora K, Eley S, Vincent D.
PURPOSE: To evaluate if pharmacogenetic testing (PT) holds value for pain-management
practitioners by identifying the potential applications of pharmacogenetic research as well as
applications in practice.
DATA SOURCES: A review of the literature was conducted utilizing the databases EBSCOhost,
Biomedical Reference Collection, CINAHL, Health Business: Full Text, Health Source:
Nursing/Academic Edition, and MEDLINE with the keywords, personalized medicine, cytochrome
P450, and phamacogenetics.
CONCLUSIONS: Chronic-pain patients present some of the most challenging patients to manage
medically. Often paired with persistent, life-altering pain, they might also have oncologic and
psychological comorbidities that can further complicate their management. One-step in-office PT
is now widely available to optimize management of complicated patients and affectively remove
the "trial-and-error" process of medication therapy.
IMPLICATIONS FOR PRACTICE: Practitioners must be familiar with the genetic determinants that
affect a patient's response to medications in order to decrease preventable morbidity and
mortality associated with drug-drug and patient-drug interactions, and to provide cost-effective
care through avoidance of inappropriate medications. Improved pain managements will improve
patient outcomes and satisfaction.
©2014 American Association of Nurse Practitioners.
Clinical Study

10. A Pharmacogenetic Test may be utilized to determine a
patient’s precision drug therapy, allowing physicians to:
 Identify patients carrying a genetic polymorphism that causes
increased or decreased CYP450 enzyme activity to metabolize
certain medications
 Identify individuals with higher risk of adverse drug reactions
 Choose more effective medications at safer dosages
 Minimize drug interactions
 Optimize pain management
 Avoid time-consuming sequential and ineffective drug trials
Minimizing Risk with Testing
Improving Patient Outcomes

11. Options for Integration Into Practice
Point of Care vs. Pharmacy Dispensing
• Pharmacogenomic tests can be administered with a topical
analgesic for pain. When a FDA approved kit with a NDC number
is utilized it is billed through a patient’s pharmaceutical benefits.
• Pharmacogenomic tests can also be administered without a
topical analgesic for pain and billed only through point of care
(POC).
• Depending upon insurance benefits, patients may have a co-pay
for the laboratory services and there is typically a co-pay for a
physician dispensed medicated kit.

12. Injectables in Practice
With the changing reimbursements, types of health care insurance, and new regulations
with regards to treatment, a medical practitioner and his or her team is under immense
time pressure to treat patients quickly, efficiently, and safely.
If a patient requires a singular or even multiple injections, the medical practitioner
must rely on his or her team to first:
 Locate the necessary and correct
injectable medications
 Ensure dating is current
 Ensure the top has not been
contaminated
 Ensure they are the correct strength and
percentage
 Ensure the liquid is not crystallized or
containing growth
 Ensure there is sufficient medication in
the vial
 Ensure that the injection has been stored
at the proper temperature and humidity
 As well as all other possible related
materials and safety precautions needed
to treat the patient.

13. CDC Safe Practices
 Whenever possible, use of single-dose vials is preferred over multiple-
dose vials, especially when medications will be administered to multiple
patients.
 Outbreaks related to unsafe injection practices indicate that some
healthcare personnel are unaware of, do not understand, or do not adhere
to basic principles of infection control and aseptic technique.
 A survey of US healthcare workers who provide medication through
injection found that 1% to 3% reused the same needle and/or syringe on
multiple patients.
 Among the deficiencies identified in recent outbreaks were a lack of
oversight of personnel and failure to follow-up on reported breaches in
infection control practices in ambulatory settings.
 Therefore, to ensure that all healthcare workers understand and adhere
to recommended practices, principles of infection control and aseptic
technique need to be reinforced in training programs and incorporated into
institutional polices that are monitored for adherence.

14. Utilizing Sterile NCD Coded Kits
The use of FDA approved single use NDC Coded Kits may be
an easy way to ensure that your practice is following CDC
guidelines.
 Storage for the material is in a single per use box
 No preparing injection trays
 Kits contain everything needed to provide a safe
procedure

15. Services Offered

16. Let’s Look at an
Average Practice

17. Pharmacogenetic Medicated Kit Dispensing
Number of Practices 1 Number of Patients per Month 320
Number of Doctors per Practice 1 Patient Capture Rate 10%
Number of Work Days per Week 4 Average Co-Pay 21%
Number of Patients per Day 20 Collect Co-Pays YES
Revenue ESTIMATED PHYSICIAN REVENUE PROJECTIONS
Advanced DNA Medicated Collection Kit™
Net Sales
Cost of Goods Sold
Gross Profit
Operation Expenses
Membership Fee *$499 for first six months. $299 after six months.
Clearinghouse Fee *Waived if member exceeds 100 transactions in the given month.
Transaction Fee per Adjudication$7.50
Total Operation Expenses
Net Income
PROJECTED MONTHLY NET REVENUE
PROJECTED ANNUAL NET REVENUE
$18,493
$789
$240
$50
$499
$231,389
$18,493
$221,921
PROJECTED ANNUAL GROSS REVENUE
Co-Pay
$19,282
PROJECTED MONTHLY GROSS REVENUE
$17,677
$19,282
$3,200
$22,482
$4,806

18. Joint, Tunnel, and Trigger Injection Kits
Number of Practices 1 Number of Patients per Month 320
Number of Doctors per Practice 1 Patient Capture Rate 10%
Number of Work Days per Week 4 Average Co-Pay 25%
Number of Patients per Day 20 Collect Co-Pays YES
Revenue ESTIMATED PHYSICIAN REVENUE PROJECTIONS
Physicians EZ Use Joint, Tunnel, and Trigger Injection Kit™
Net Sales
Cost of Goods Sold
Gross Profit
Operation Expenses
Membership Fee *$499 for first six months. $299 after six months.
Clearinghouse Fee *Waived if member exceeds 100 transactions in the given month.
Transaction Fee per Adjudication$7.50
Total Operation Expenses
Net Income
PROJECTED MONTHLY NET REVENUE
PROJECTED ANNUAL NET REVENUE
$6,703
$789
$240
$50
$499
$89,907
$6,703
$80,439
PROJECTED ANNUAL GROSS REVENUE
Co-Pay
$7,492
PROJECTED MONTHLY GROSS REVENUE
$8,066
$7,492
$3,296
$10,788
$2,722

19. B-12 Injection Kits
Number of Practices 1 Number of Patients per Month 320
Number of Doctors per Practice 1 Patient Capture Rate 10%
Number of Work Days per Week 4 Average Co-Pay 32%
Number of Patients per Day 20 Collect Co-Pays YES
Revenue ESTIMATED PHYSICIAN REVENUE PROJECTIONS
Physicians EZ Use B-12 Compliance Injection Kit™
Net Sales
Cost of Goods Sold
Gross Profit
Operation Expenses
Membership Fee *$499 for first six months. $299 after six months.
Clearinghouse Fee *Waived if member exceeds 100 transactions in the given month.
Transaction Fee per Adjudication$7.50
Total Operation Expenses
Net Income
PROJECTED MONTHLY NET REVENUE
PROJECTED ANNUAL NET REVENUE
$5,629
$789
$240
$50
$499
$77,019
$5,629
$67,551
PROJECTED ANNUAL GROSS REVENUE
Co-Pay
$6,418
PROJECTED MONTHLY GROSS REVENUE
$5,934
$6,418
$2,336
$8,754
$2,820

20. Practice Projection with 10% Penetration
Pharmacogenetic Medicated Kit Dispensing $18,493
Joint, Tunnel and Trigger Injection Kits $6,703
B-12 Compliance Injection $5,629
Total Monthly Net Revenue $30,825.00
Total Annual Net Revenue $369,900.00

21. Let’s Get Your Questions Answered
 How do I get started?
 What are the costs?
 What are the steps in the process?
 Who schedules my staff trainings?
What else do you need to know in order to get started?