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PITUITARY GLAND


NAME: HINGIN BIN CHIAM TAH KONG
        LU SIEW LING

GROUP:9
   Lies in sella turcica and is connected to
    hypothalamus by pituitary stalk.
   Divisible 2 distinctive portions: ANTERIOR and
    POSTERIOR pituitary. (adenohypophysis and
    neurohypophysis)
   Between it : pars intermedia
   Anterior pituitary originates: Rathke’s
    Pouch(invagination of the pharangeal
    epithelium)
   Posterior pituitary originates: neural tissue
    outgrowth from the hypothalamus (glial-type
    cells)
    6 important peptide hormones secreted by
     anterior pituitary gland(plays major role in
     metabolism):
a)    Growth hormones
b)    Adrenocorticotrophin
c)    Thyroid stimulating hormones
d)    Prolactin
e)    Follicle stimulating hormones and luteinizing
      hormone
    Posterior pituitary gland secreted 2 other
     peptide hormones:
a)    Antidiuretic hormones (Vasopressin)
b)    Oxytoxin
   Pituitary secretion is controlled by either
    hormonal or nervous signals from hypothalamus
   Anterior: controlled by hormones (hypothalamic
    releasing, hypothalamic inhibitory hormones)
        - is secreted form the hypothalamus then
        conducted through minute blood vessels
        (hypothalamic-hypophysial porta vessels)
        which penetrates substance of median
        eminance  pituitary stalk supply blood
        for anterior pituitary sinuses.
   Posterior: from hypothalamus by nerve signals
   Thyrotropin-releasing hormones
   Corticotrophin-releasing hormones
   Growth hormones-releasing hormones and
    Somatostatin
   Gonadotropin-releasing hormones
   Prolactin inhibitory hormones
   Anterior: these hormones acts on glandular
    cells to controlled the secretion
   Many sources in nervous system
    hypothalamus( collecting center for
    information )
   Growth hormones(GH) does not function through
    target gland but exerts it’s effects directly on mainly
    all tissue of the body.
   Cause growth almost all tissue that can grow
   Increasing of the cells and mitosis
   Promoting protein deposition and increase protein
    synthesis rate in most cells of the body.
   Increase mobalizamobalization of fatty acids from
    adipose tissue, free fatty acids in blood, use fatty
    acids for energy
   Decreased glucose utilization rate through body
    - decreased glucose uptake(in skeletal muscles)
    - increased glucose production(liver)
    - increased insulin secretion
   GH secretion in a pulsatile pattern, increased and
    decreased. Factors related to person state of
    nutrition or stress(stimulate secretion):
    - starvation (kwashiorkor)
    - hypoglycemia, exercise, excitement, trauma
   Factor stimulate growth hormone:
    - decreased blood glucose and free fatty acids
    - starvation or fasting, protein deficiency
    - trauma, stress, excitement, exercise
   Inhibit GH secretion:
    - increased blood glucose, blood free fatty acids
    -aging , obesity, somatostatin, GH (exogenous)
    - somatomedins ( insulin-like growth factor)
Pituitary gland
Pituitary gland

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Pituitary gland

  • 1. PITUITARY GLAND NAME: HINGIN BIN CHIAM TAH KONG LU SIEW LING GROUP:9
  • 2. Lies in sella turcica and is connected to hypothalamus by pituitary stalk.  Divisible 2 distinctive portions: ANTERIOR and POSTERIOR pituitary. (adenohypophysis and neurohypophysis)  Between it : pars intermedia  Anterior pituitary originates: Rathke’s Pouch(invagination of the pharangeal epithelium)  Posterior pituitary originates: neural tissue outgrowth from the hypothalamus (glial-type cells)
  • 3. 6 important peptide hormones secreted by anterior pituitary gland(plays major role in metabolism): a) Growth hormones b) Adrenocorticotrophin c) Thyroid stimulating hormones d) Prolactin e) Follicle stimulating hormones and luteinizing hormone
  • 4. Posterior pituitary gland secreted 2 other peptide hormones: a) Antidiuretic hormones (Vasopressin) b) Oxytoxin
  • 5. Pituitary secretion is controlled by either hormonal or nervous signals from hypothalamus  Anterior: controlled by hormones (hypothalamic releasing, hypothalamic inhibitory hormones) - is secreted form the hypothalamus then conducted through minute blood vessels (hypothalamic-hypophysial porta vessels) which penetrates substance of median eminance  pituitary stalk supply blood for anterior pituitary sinuses.  Posterior: from hypothalamus by nerve signals
  • 6. Thyrotropin-releasing hormones  Corticotrophin-releasing hormones  Growth hormones-releasing hormones and Somatostatin  Gonadotropin-releasing hormones  Prolactin inhibitory hormones  Anterior: these hormones acts on glandular cells to controlled the secretion  Many sources in nervous system hypothalamus( collecting center for information )
  • 7. Growth hormones(GH) does not function through target gland but exerts it’s effects directly on mainly all tissue of the body.  Cause growth almost all tissue that can grow  Increasing of the cells and mitosis  Promoting protein deposition and increase protein synthesis rate in most cells of the body.  Increase mobalizamobalization of fatty acids from adipose tissue, free fatty acids in blood, use fatty acids for energy  Decreased glucose utilization rate through body - decreased glucose uptake(in skeletal muscles) - increased glucose production(liver) - increased insulin secretion
  • 8. GH secretion in a pulsatile pattern, increased and decreased. Factors related to person state of nutrition or stress(stimulate secretion): - starvation (kwashiorkor) - hypoglycemia, exercise, excitement, trauma  Factor stimulate growth hormone: - decreased blood glucose and free fatty acids - starvation or fasting, protein deficiency - trauma, stress, excitement, exercise  Inhibit GH secretion: - increased blood glucose, blood free fatty acids -aging , obesity, somatostatin, GH (exogenous) - somatomedins ( insulin-like growth factor)