This document summarizes the structure and function of the three main types of muscle tissues - skeletal, smooth, and cardiac muscle. It describes the sarcomere as the basic contractile unit of myofibrils composed of thin actin filaments and thick myosin filaments. Contraction occurs via the sliding filament mechanism when myosin cross-bridges attach to and pull on actin filaments, shortening the sarcomere. Key regulatory proteins troponin and tropomyosin prevent contraction in low-calcium conditions by blocking the actin-myosin interaction.
Describes the action potential occuring in the muscle. It includes the cellular and molecular organization of the muscle particularly on the myosin and actin myofilaments. Describes likewise the steps of muscle contraction.
Describes the overview of the skeletal muscles, its description, functons, and properties. It also inccludes the gross organization of the skeletal system.
Describes the action potential occuring in the muscle. It includes the cellular and molecular organization of the muscle particularly on the myosin and actin myofilaments. Describes likewise the steps of muscle contraction.
Describes the overview of the skeletal muscles, its description, functons, and properties. It also inccludes the gross organization of the skeletal system.
i've used this note before this for my first year medicine in egypt. Fot those who taking this course(medicine) , I hope it'll give some ideas to you to study about this subject.
Goodluck :) !
Functions of Muscle Tissue
• Producing body movements
• Stabilizing body positions
• Regulating organ volumes
– bands of smooth muscle called sphincters
• Movement of substances within the body
– blood, lymph, urine, air, food and fluids, sperm
• Producing heat
– involuntary contractions of skeletal muscle (shivering
i've used this note before this for my first year medicine in egypt. Fot those who taking this course(medicine) , I hope it'll give some ideas to you to study about this subject.
Goodluck :) !
Functions of Muscle Tissue
• Producing body movements
• Stabilizing body positions
• Regulating organ volumes
– bands of smooth muscle called sphincters
• Movement of substances within the body
– blood, lymph, urine, air, food and fluids, sperm
• Producing heat
– involuntary contractions of skeletal muscle (shivering
Chemical and molecular basis of muscle contractionChirag Dhankhar
here in this ppt I have told about the different types of muscles their biological cycle of muscle contraction, needs of contraction, neural network working for muscle contraction, atp and cp energy use in muscles , how energy is used and made by muscles in middle of the exercise, anatomy of muscles, working of muscles, different types of bands and proteins needed for muscle contraction
Isometric. If I hold the weight still, the muscle is engaged but doesn't change length. ...
Concentric. When I bring that weight towards my shoulder, the biceps muscle shortens
Dr. K. Rama Rao
Govt. Degree College
TEKKALI; Srikakulam Dt. A. P
Phone: 9010705687
Key Trends Shaping the Future of Infrastructure.pdfCheryl Hung
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Cheryl Hung, ochery.com
Sr Director, Infrastructure Ecosystem, Arm.
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Paper presented at SYNERGY workshop at AVI 2024, Genoa, Italy. 3rd June 2024
https://alandix.com/academic/papers/synergy2024-epistemic/
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Let's dive deeper into the world of ODC! Ricardo Alves (OutSystems) will join us to tell all about the new Data Fabric. After that, Sezen de Bruijn (OutSystems) will get into the details on how to best design a sturdy architecture within ODC.
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Watch this recorded webinar about real-time monitoring of application performance. See how to integrate Apache JMeter, the open-source leader in performance testing, with InfluxDB, the open-source time-series database, and Grafana, the open-source analytics and visualization application.
In this webinar, we will review the benefits of leveraging InfluxDB and Grafana when executing load tests and demonstrate how these tools are used to visualize performance metrics.
Length: 30 minutes
Session Overview
-------------------------------------------
During this webinar, we will cover the following topics while demonstrating the integrations of JMeter, InfluxDB and Grafana:
- What out-of-the-box solutions are available for real-time monitoring JMeter tests?
- What are the benefits of integrating InfluxDB and Grafana into the load testing stack?
- Which features are provided by Grafana?
- Demonstration of InfluxDB and Grafana using a practice web application
To view the webinar recording, go to:
https://www.rttsweb.com/jmeter-integration-webinar
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UI automation Introduction,
UI automation Sample
Desktop automation flow
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Deepak Rai, Automation Practice Lead, Boundaryless Group and UiPath MVP
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In this presentation, we examine the challenges and limitations of relying too heavily on PHP frameworks in web development. We discuss the history of PHP and its frameworks to understand how this dependence has evolved. The focus will be on providing concrete tips and strategies to reduce reliance on these frameworks, based on real-world examples and practical considerations. The goal is to equip developers with the skills and knowledge to create more flexible and future-proof web applications. We'll explore the importance of maintaining autonomy in a rapidly changing tech landscape and how to make informed decisions in PHP development.
This talk is aimed at encouraging a more independent approach to using PHP frameworks, moving towards a more flexible and future-proof approach to PHP development.
DevOps and Testing slides at DASA ConnectKari Kakkonen
My and Rik Marselis slides at 30.5.2024 DASA Connect conference. We discuss about what is testing, then what is agile testing and finally what is Testing in DevOps. Finally we had lovely workshop with the participants trying to find out different ways to think about quality and testing in different parts of the DevOps infinity loop.
Slack (or Teams) Automation for Bonterra Impact Management (fka Social Soluti...Jeffrey Haguewood
Sidekick Solutions uses Bonterra Impact Management (fka Social Solutions Apricot) and automation solutions to integrate data for business workflows.
We believe integration and automation are essential to user experience and the promise of efficient work through technology. Automation is the critical ingredient to realizing that full vision. We develop integration products and services for Bonterra Case Management software to support the deployment of automations for a variety of use cases.
This video focuses on the notifications, alerts, and approval requests using Slack for Bonterra Impact Management. The solutions covered in this webinar can also be deployed for Microsoft Teams.
Interested in deploying notification automations for Bonterra Impact Management? Contact us at sales@sidekicksolutionsllc.com to discuss next steps.
Smart TV Buyer Insights Survey 2024 by 91mobiles.pdf91mobiles
91mobiles recently conducted a Smart TV Buyer Insights Survey in which we asked over 3,000 respondents about the TV they own, aspects they look at on a new TV, and their TV buying preferences.
GraphRAG is All You need? LLM & Knowledge GraphGuy Korland
Guy Korland, CEO and Co-founder of FalkorDB, will review two articles on the integration of language models with knowledge graphs.
1. Unifying Large Language Models and Knowledge Graphs: A Roadmap.
https://arxiv.org/abs/2306.08302
2. Microsoft Research's GraphRAG paper and a review paper on various uses of knowledge graphs:
https://www.microsoft.com/en-us/research/blog/graphrag-unlocking-llm-discovery-on-narrative-private-data/
LF Energy Webinar: Electrical Grid Modelling and Simulation Through PowSyBl -...DanBrown980551
Do you want to learn how to model and simulate an electrical network from scratch in under an hour?
Then welcome to this PowSyBl workshop, hosted by Rte, the French Transmission System Operator (TSO)!
During the webinar, you will discover the PowSyBl ecosystem as well as handle and study an electrical network through an interactive Python notebook.
PowSyBl is an open source project hosted by LF Energy, which offers a comprehensive set of features for electrical grid modelling and simulation. Among other advanced features, PowSyBl provides:
- A fully editable and extendable library for grid component modelling;
- Visualization tools to display your network;
- Grid simulation tools, such as power flows, security analyses (with or without remedial actions) and sensitivity analyses;
The framework is mostly written in Java, with a Python binding so that Python developers can access PowSyBl functionalities as well.
What you will learn during the webinar:
- For beginners: discover PowSyBl's functionalities through a quick general presentation and the notebook, without needing any expert coding skills;
- For advanced developers: master the skills to efficiently apply PowSyBl functionalities to your real-world scenarios.
Search and Society: Reimagining Information Access for Radical FuturesBhaskar Mitra
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2. Structure Muscles cells generate force and movements used to regulate the internal environment, and they also produce movements in the external environment. Ex. skeletal muscle, smooth muscle, and cardiac muscle
3. Types of Muscle Tissues Skeletal muscles its contraction is responsible for supporting and moving the skeleton. contraction of skeletal muscle is initiated by impulses in the neurons to the muscle and is usually under voluntary control
4. Types of Muscle Tissues Smooth muscles Surround various hollow organs and tubes, Ex. stomach, intestines, urinary bladder, uterus, blood vessels, and airways in the lungs. The autonomic nervous system, hormones, autocrine/paracrine agents, and other local chemical signals control smooth muscle contraction. Some smooth muscles contract autonomously, however, even in the absence of such signals. Smooth muscle is not normally under voluntary control.
5. Types of Muscle Tissues Straited (Cardiac) Muscle Muscle of the heart Contraction propels blood through the circulatory system
6. Skeletal muscles Muscle fiber A single skeletal muscle cell Formed by fusion of undifferentiated, mononucleated cells, known as myoblasts into single cylindrical, multinucleated cell.
7. Structures Skeletal muscle differentiation is completed around the time of birth Continue to increase in size during growth from infancy to adult, but no new fibers are formed from myoblasts. If skeletal-muscle fibers are destroyed after birth as a result of injury, they cannot be replaced. New fibers can be formed, however, from undifferentiated cells known as satellite cells Does not restore a severely damaged muscle to full strength.
8. Structures Muscle refers to a number of musclefibers bound together by connective tissue. Tendons Collagen fibers that links the muscles and bones Located at each end of the muscles
9. Structures Striated muscles Under light microscope, is a series of light and dark bands perpendicular to the long axis of the fiber ex. Cardiac muscles Myofibrils cylindrical bundles with thick and thin filaments in the cytoplasm Cytoplasm of fiber is filled with myofibrils Skeletal-muscle fibers viewed through a light microscope. Each bracket at the left indicates one muscle fiber. Arrow indicates a blood vessel containing red blood cells.
10. Myofibrils Sarcomere One repeating unit of thick and thin filament in the myofibril Thick filaments Composed of contractile protein myosin Found in middle of sarcomere where their order parallel produces wide, dark A bands Thin filaments Composed of contractile protein actin As well as Troponin and Tropomyosin (regulation contraction)
11.
12. Structures Each sarcomere contains 2 sets of thin filaments One end of each thin filament is anchored to a network of interconnecting protein called Z line Other end overlaps a portion of the thick filament I bands Light bands that lies between the ends of the A bands of two adjacent sarcomeres and contains those portions of the thin filaments that do not overlap the thick filaments. H zone Narrow light band in the center of the A band Only thick filaments, specifically their central parts, are found in the H zone M line Narrow, dark band in the center of the H zone Corresponds to proteins that link together the central region of the thick filaments
14. Structures Titin A protein that functions as a molecular spring which is responsible for the passive elasticity of muscle Extends from Z line to M line linked to both the M-line proteins and the thick filaments
15. Structures Cross bridges Projections that bridges the space between overlapping thick and thin filaments portions of myosin molecules that extend from the surface of the thick filaments toward the thin filaments During contraction, the cross bridges make contact with the thin filaments and exert force on them
17. Contraction-turning on of the force-generating sites( cross bridges) in a muscle fiber. Relaxation- force generation is turned off and tension declines. the emotional state of low tension. Contraction and Relaxation
18. The sliding filament theory is the explanation for how muscles produce force (or, usually, shorten). It explains that the thick and thin filaments within the sarcomere slide past one another, shortening the entire length of the sarcomere. Sliding filament mechanism
19. Actin- globular proteins composed of a single polypeptide that polymerizes with other actins to form two intertwined helical chains. Actin-thin filament. Myosin-thick filament.
20. Is the sequence of events that occur between the time a cross bridge binds to a thin filament, moves, and then is set to repeat the process. Cross bridge cycle
21. 1. attachment of the cross bridge to the thin filament. 2. movement of cross bridge, producing tension on the thin filament. 3. detachment of the cross bridge from the thin filament. 4. energizing of the cross bridge for it to repeat the cycle. Cross bridge cycle
22. 1. (ATP hydrolysis) provides energy for cross-bridge movement 2. ATP binding tom myosin breaks the link formed between actin and myosin during cycle, allowing the cycle to be repeated. Roles of ATP
24. Tropomyosin and troponin are proteins that prevents cross bridges from interacting with actinin resting muscle fiber. Calcium triggers contraction by reaction with regulatory proteins that in the absence of calcium prevent interaction of actin and myosin. Introduction
25. Is a complex of three regulatory proteins that is essential to muscle contraction. Troponin is attached to the protein tropomyosin and lies within the groove between actin filaments in muscle tissue. Troponin
26. Troponin C-binds to calcium ions to produce a conformational change in TnI Troponin T-binds to tropomyosin, interlocking them to form a troponin-tropomyosin complex Troponin I-binds to actin in thin myofilaments to hold the troponin-tropomyosin complex in place Individual subunits serve different functions:
27.
28. Is an actin-binding protein that regulates actin mechanics. Chains of tropomyosin molecules are arranged end to end along the actin filament. It inhibits contraction by blocking the interaction of actin and myosin, except when influenced by troponin. Tropomyosin
29. Muscle contraction is regulated by calcium ions, which will change thin filament into an activated state by binding to troponin. Removal of calcium from troponin reverses the process, turning off contractions. Calcium