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Ultrastructure of skeletal
muscle
NEETHU SIVAN S
The Muscular System
Muscles are responsible for all types of body movement – they
contract or
 shorten and are the machine of the body
 Three basic muscle types are found in the body
 Skeletal muscle
 Cardiac muscle
 Smooth muscle
Characteristics of Muscles
 Muscle cells are elongated
 (muscle cell = muscle fibber)
 Contraction of muscles is due to the movement of microfilaments
 All muscles share some terminology
 Prefix myo refers to muscle
 Prefix mys refers to muscle
 Prefix sarco refers to flesh
Skeletal Muscle Characteristics
 Most are attached by tendons to bones
 Cells are multinucleate
 Striated – have visible banding
 Voluntary – subject to conscious control
 Cells are surrounded and bundled by connective tissue = great force, but
tires easily
• Cells are multinucleate
• Nuclei are just beneath the
sarcolemma
Sarcolemma – specialized plasma membrane
Sarcoplasmic reticulum – specialized smooth endoplasmic reticulum
Myofibril
 Bundles of myofilaments
Myofibrils are aligned to give distinct bands
 •I band = light band
 •A band = dark band
Sarcomere
Contractile unit of a muscle fiber
Organization of the sarcomere
 •Thick filaments = myosin filaments
 •Composed of the protein myosin
 •Has ATPase enzymes
Properties of Skeletal Muscle Activity (single cells or fibers)
 Irritability – ability to receive and respond to a stimulus
 Contractility – ability to shorten when an adequate stimulus is received
Questions
 What is fascicle ?
 What is muscle cell?
 What is the function of myofibril?
 How do the skeletal muscle differ from smooth muscle?
 What are the characterisitcs of heart muscle?
 Explain briefly the structure of skeletal muscle?
Home work
 Prepare a note on the structure of the skeletal muscle in your diary
 Prepare a chart on the structure of skeletal muscle

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Ultrastructure of skeletal muscle

  • 2. The Muscular System Muscles are responsible for all types of body movement – they contract or  shorten and are the machine of the body  Three basic muscle types are found in the body  Skeletal muscle  Cardiac muscle  Smooth muscle
  • 3. Characteristics of Muscles  Muscle cells are elongated  (muscle cell = muscle fibber)  Contraction of muscles is due to the movement of microfilaments  All muscles share some terminology  Prefix myo refers to muscle  Prefix mys refers to muscle  Prefix sarco refers to flesh
  • 4. Skeletal Muscle Characteristics  Most are attached by tendons to bones  Cells are multinucleate  Striated – have visible banding  Voluntary – subject to conscious control  Cells are surrounded and bundled by connective tissue = great force, but tires easily
  • 5.
  • 6. • Cells are multinucleate • Nuclei are just beneath the sarcolemma
  • 7. Sarcolemma – specialized plasma membrane Sarcoplasmic reticulum – specialized smooth endoplasmic reticulum Myofibril  Bundles of myofilaments Myofibrils are aligned to give distinct bands  •I band = light band  •A band = dark band
  • 8. Sarcomere Contractile unit of a muscle fiber Organization of the sarcomere  •Thick filaments = myosin filaments  •Composed of the protein myosin  •Has ATPase enzymes
  • 9.
  • 10.
  • 11. Properties of Skeletal Muscle Activity (single cells or fibers)  Irritability – ability to receive and respond to a stimulus  Contractility – ability to shorten when an adequate stimulus is received
  • 12. Questions  What is fascicle ?  What is muscle cell?  What is the function of myofibril?  How do the skeletal muscle differ from smooth muscle?  What are the characterisitcs of heart muscle?  Explain briefly the structure of skeletal muscle?
  • 13. Home work  Prepare a note on the structure of the skeletal muscle in your diary  Prepare a chart on the structure of skeletal muscle