Retrograde tibiotalocalcaneal nailing provides a novel single-stage approach to addressing hindfoot arthritis associated with tibial malunion or nonunion. The technique involves correcting tibial alignment via osteotomy and fusing the ankle and subtalar joints using a retrograde nail. In a study of 25 patients, all malunions and nonunions healed without loss of correction. Hindfoot alignment and function were restored, with 94% of patients reporting being satisfied or extremely satisfied. The technique provides an alternative to external fixation or staged procedures for treating this complex problem.
Deformity: It’s the position of a limb/Joint, from which it cannot be brought back to its normal anatomical position.
Described as abnormalities of :
Length
Angulation
Rotation
Translation
Combination
Surgical Approaches to Acetabulum and PelvisBijay Mehta
Important surgical approaches to acetabulum and pelvis are described.
Ilioinguinal approach, Modified Stoppa Approach, Kocher lagenbeck Approach, Ilifemoral approach and extensile approaches are well illustrated and described.
High tibial osteotomy (HTO) is a common and widely accepted procedure in orthopaedic surgery. In the literature, we find descriptions of the technique dating back to the 50s, with Jackson (Jackson, 1958). However, it was not until the 70s, with the publications of Conventry (Coventry, 1969 and 1973) and Insall (Insall, 1975), that proximal tibial osteotomy became common practice as a treatment option for medial compartment osteoarthritis of the knee usually associated to varus deformity. At that time, closing wedge osteotomies were performed, despite the greater technical difficulty and risks involved, as there were no fixation materials available that could enable opening wedge osteotomy. Only after the development of medial wedge plate fixation that opening wedge osteotomy became applicable (Puddu, 2004).
The goals of HTO are:
1. To reduce knee pain by transferring weight-bearing loads to the relatively unaffected compartment;
2. To increase the life span of the knee joint, by slowing or stopping the destruction of the medial joint compartment. This could delay the need of a joint replacement.
Deformity: It’s the position of a limb/Joint, from which it cannot be brought back to its normal anatomical position.
Described as abnormalities of :
Length
Angulation
Rotation
Translation
Combination
Surgical Approaches to Acetabulum and PelvisBijay Mehta
Important surgical approaches to acetabulum and pelvis are described.
Ilioinguinal approach, Modified Stoppa Approach, Kocher lagenbeck Approach, Ilifemoral approach and extensile approaches are well illustrated and described.
High tibial osteotomy (HTO) is a common and widely accepted procedure in orthopaedic surgery. In the literature, we find descriptions of the technique dating back to the 50s, with Jackson (Jackson, 1958). However, it was not until the 70s, with the publications of Conventry (Coventry, 1969 and 1973) and Insall (Insall, 1975), that proximal tibial osteotomy became common practice as a treatment option for medial compartment osteoarthritis of the knee usually associated to varus deformity. At that time, closing wedge osteotomies were performed, despite the greater technical difficulty and risks involved, as there were no fixation materials available that could enable opening wedge osteotomy. Only after the development of medial wedge plate fixation that opening wedge osteotomy became applicable (Puddu, 2004).
The goals of HTO are:
1. To reduce knee pain by transferring weight-bearing loads to the relatively unaffected compartment;
2. To increase the life span of the knee joint, by slowing or stopping the destruction of the medial joint compartment. This could delay the need of a joint replacement.
Basics of patellofemoral instability for postgraduates. Gives brief introduction about patellofemoral joint anatomy, causes, examintaion and treatment for patellofemoral instability
An Introduction, History, Diagnosis, Current Guidelines on Treatment of trochanteric fractures of femur. Presentation also contain an introduction of Dynamic Hip Screw and Surgical Techniques.
Similar to Ortho Journal Club 11 by Dr Saumya Agarwal (20)
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
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Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
1. Addressing Hindfoot Arthritis with
Concomitant Tibial Malunion or Nonunion with
Retrograde TibioTaloCalcaneal Nailing: A Novel
Treatment Approach
Justin M. Kane et al
Rothman Institute at Thomas Jefferson University Hospital, Philadelphia,
Pennsylvania
Journal of Bone and Joint Surgery
| April 2014 | Vol. 96-A | Number 7
Level of evidence I
PRESENTER : Dr SAUMYAAGARWAL
Junior resident Dept of Orthopaedics J.N. Medical College and Dr.
Prabhakar Kore Hospital and MRC, Belgaum
2. INTRODUCTION
• Tibial shaft fractures are most common
long bone fractures with incidence upto
26 / lakh people
• Malunion and nonunion most common with
tibial shaft fractures
• Prearthrotic deformity - coined by rosemeyer and
described as effect of angular deformity of tibia on
distribution of weight across adjacent joints
3. REVIEW OF LITERATURE
• Sarmiento found deformity 0f >5⁰ ---> late onset
degenerative changes in adjacent joints
• Puno et al concluded - anatomic reduction could
reduce abnormal forces at adjacent joints and
possibly delay arthritis at ankle
• Tarr et al found - more distal the deformity,
greater the impact on incongrous tibiotalar
contact area
4. • Milner et al evaluated late onset arthritis post
tibial shaft fractures and found more
osteoarthritis in knee and ankle on injured
extremity.
5. Various Treatment Options
1. Tibial osteotomy with ankle arthrodesis/
arthroplasty
2. External fixation to correct malunion or
nonunion with ankle arthrodesis
3. Tibiocalcaneal nail fixation for correction of
malunion or nonunion and arthrodesis of
ankle
6. METHODS
• A retrospective study
• Patients who underwent single stage
reconstruction for tibia malunion or nonunion
with tibiotalar arthritis were assessed
• Visual Analog Scale and American Orthopaedic
Foot and Ankle Society – Ankle Hindfoot scores
were used to assess
7. Exclusion Criteria
• Active infection
• Leg length discrepancy of >5cm
• Malunion or nonunion at ankle joint
secondary to ankle fracture
• Treatment with a staged procedure or single
stage deformity correction with arthroplasty
8. • 25 patients underwent single stage correction of
tibial malunion or nonunion with
tibiotalocalcaneal nailing
• Average age – 58 yrs
• 13 men and 12 women
• 3 patients had severe rheumatoid arthritis
• 8 patients had peripheral neuropathy
9. • 16 had healed angular malunion
• 4 had combined malunion and nonunion
• 5 had tibial nonunion
13. • Overall average sagittal plane malalignment was
26⁰ and average coronal plane malalignment
was 21⁰
• Ankle joint arthritis was assessed for pain, ROM
and palpable crepitus
• AP, Mortise and lateral views were taken
• Weight bearing radiographs were taken to
assess joint space narrowing, subchondral
sclerosis and osteophyte formation
14. • Subtalar joint and transverse tarsal joints were
assessed independently
• An inflexible subtalar joint can decrease ability
to correct alignment and lead to undesirable
results
• Inclusion of subtalar joint in arthritis, aided in
correction of deformity and allowed use of
single device to treat arthritis and malunion
15. • Author hypothesized that whenever subtalar
involvement was suspected, that joint should be
included in fusion to improve the final
alignment and stability
• All patients underwent a single stage
reconstruction including deformity correction
via realignment osteotomy combined with
arthrodesis of ankle and subtalar joint
16. Surgical Technique
• Osteotomy requires preoperative radiographic
planning to establish centre of rotation axis of
deformity and to plan for triplanar cuts for
deformity correction
• Under C-arm, k-wires are drilled across tibia
• Author suggest multiple drill holes along plane of
planned cut using drill bit with continuous
irrigation
17. • Correction should be achieved in all planes i.e.,
coronal, sagittal and rotational
• Fine adjustments were made using
microsagittal saw until required alignment is
obtained, recreating mechanical axis of limb
• After correction of proximal alignment, ankle
and subtalar joints are prepared exposing
subchondral bone
18. • Definitive fixation is obtained with retrograde
intramedullary nail inserted through plantar
aspect of calcaneum into tibial shaft ending 5
cm proximal to level of deformity correction
• 15, 20 and 25cm length nail has been used
according to fracture site
• Distal part of fibula and iliac crest was used for
bone grafting
19.
20. • 19 patients underwent tibiotalolcalcaneal
fusion , 6 underwent pantalar (talonavicular
and calcaneocuboid) fusion
• Transverse tarsal joints are approached through
standard open incisions, articular cartilage and
subchondral bone is removed and joints
derotated to neutral
• Fixation is obtained with 2 parallel retrograde
screws across talonavicular joint and staples
across calcaneocuboid joint
21. • Non weight bearing was advised for 6 weeks
for traumatic patients and 12 weeks for
patients having neuropathy
• Healing was assessed clinically and
radiographically
• 1 patient developed infection because of
additional surgery and had poor result and
was unsatisfied
22. RESULTS
• All nonunions, osteotomy sites and fusion sites
healed clinically and radiographically at an average
of 19.5 weeks
• Radiographs at final follow up showed continued
stable healing of fusion and osteotomy sites without
loss of alignment
• All deformities were corrected to neutral alignment
and all patients had a plantigrade foot and ability to
wear off the shelf shoes without bracing
23.
24. • 21 patients were extremely satisfied
• 3 were satisfied
• 1 was not satisfied
25. DISCUSSION
• Retrograde intramedullary nailing for tibiotalo
calcaneal arthrodesis is described as a salvage
procedure for patients with
• a failed ankle fusion or
• total ankle arthroplasty with severe bone loss,
• charcot arthropathy,
26. • rheumatoid arthritis,
• posttraumatic arthritis,
• previous talectomy,
• bone loss after tumor resection,
• tuberculous arthropathy
27. • High rate of fusion and biomechanical strength
of construct successfully achieves a painless
biomechanically stable plantigrade foot
• Various studies showed high fusion rate around
90%
• Study recommends inclusion of subtalar joint
and utilization of intramedullary device to
ensure deformity correction and a stable ankle
hindfoot construct
29. CONCLUSION
• Single stage procedure of tibial osteotomy and
retrograde intramedullary nailing for correction
of angular deformity and fusion of arthritic
hindfoot :
provides a viable alternative to
multiplanar external fixation or a staged
procedure
• Accurate correction with meticulous joint
preparation is required to achieve good results.