When walking, a series of neural processes occur to facilitate coordinated muscle contraction. Signals are sent from sensory neurons in the spinal cord to motor neurons, activating motor units and causing muscle fibers to contract. Both fast twitch and slow twitch fibers are used, with more reliance on slow twitch fibers for continuous walking. Muscle spindles and golgi tendon organs provide feedback on muscle length and force to ensure proper gait. Over time, motor unit plasticity results in neural adaptations that optimize walking performance.
This PPT covers the entire concepts in Muscular System. It includes details of 3 types of muscular tissue like Skeletal, cardiac and smooth muscle. Concepts of contraction cycle, sliding filament mechanism, neuromuscular junction, muscle metabolism, muscle tone and Different types of contraction.
1. Locomotion
2. Vasoconstriction and vasodilatation- constriction and
dilation of blood vessel Walls are the results of smooth muscle
contraction.
3. Peristalsis – wavelike motion along the digestive tract is
produced by the Smooth muscle.
4. Cardiac motion
5. Posture maintenance- contraction of skeletal muscles
maintains body posture and muscle tone.
6. Heat generation – about 75% of ATP energy used in
muscle contraction is released as heat. 1. Contracts for a longer time than skeletal muscle
because transverse tubules supply extra Ca+2 ions .
2. intercalated disc connects the ends of adjacent
muscles and hold cells together as a unit (syncytium) .
3. Fibers contracts as a unit .
4. Muscle fibers are self – exiting , rhythmic , and
remain refractory until a contraction is completed.
Describes the action potential occuring in the muscle. It includes the cellular and molecular organization of the muscle particularly on the myosin and actin myofilaments. Describes likewise the steps of muscle contraction.
i've used this note before this for my first year medicine in egypt. Fot those who taking this course(medicine) , I hope it'll give some ideas to you to study about this subject.
Goodluck :) !
This PPT covers the entire concepts in Muscular System. It includes details of 3 types of muscular tissue like Skeletal, cardiac and smooth muscle. Concepts of contraction cycle, sliding filament mechanism, neuromuscular junction, muscle metabolism, muscle tone and Different types of contraction.
1. Locomotion
2. Vasoconstriction and vasodilatation- constriction and
dilation of blood vessel Walls are the results of smooth muscle
contraction.
3. Peristalsis – wavelike motion along the digestive tract is
produced by the Smooth muscle.
4. Cardiac motion
5. Posture maintenance- contraction of skeletal muscles
maintains body posture and muscle tone.
6. Heat generation – about 75% of ATP energy used in
muscle contraction is released as heat. 1. Contracts for a longer time than skeletal muscle
because transverse tubules supply extra Ca+2 ions .
2. intercalated disc connects the ends of adjacent
muscles and hold cells together as a unit (syncytium) .
3. Fibers contracts as a unit .
4. Muscle fibers are self – exiting , rhythmic , and
remain refractory until a contraction is completed.
Describes the action potential occuring in the muscle. It includes the cellular and molecular organization of the muscle particularly on the myosin and actin myofilaments. Describes likewise the steps of muscle contraction.
i've used this note before this for my first year medicine in egypt. Fot those who taking this course(medicine) , I hope it'll give some ideas to you to study about this subject.
Goodluck :) !
How can you deal with Fuzzy Logic. Fuzzy logic is a form of many-valued logic; it deals with reasoning that is approximate rather than fixed and exact. In contrast with traditional logic theory, where binary sets have two-valued logic: true or false, fuzzy logic variables may have a truth value that ranges in degree
between 0 and 1
basic nervous system-CNS-PNS -cell bodie- axon-dendron-grye matter- white mat...shailesh sangle
The nervous system is a complex network of cells, tissues, and organs that coordinates and regulates the body's responses to internal and external stimuli. It is responsible for the control and coordination of all the body's functions, including movement, sensation, thought, and behavior.
The nervous system can be divided into two main parts: the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS consists of the brain and spinal cord, while the PNS consists of all the nerves that extend from the CNS to the rest of the body.
The nervous system is made up of different types of cells, including neurons and glial cells. Neurons are specialized cells that transmit signals through the body in the form of electrical impulses. Glial cells, on the other hand, support and protect the neurons and help maintain the proper functioning of the nervous system.
The nervous system is responsible for many vital functions, including:
Sensory processing: The nervous system receives sensory information from the environment and the body's internal organs, and processes and interprets this information to generate appropriate responses.
Motor control: The nervous system controls the muscles and other organs of the body to produce movement and other responses.
Cognitive functions: The nervous system is responsible for the processes of learning, memory, language, and other complex mental activities.
Autonomic functions: The nervous system regulates the body's automatic functions, such as breathing, heart rate, digestion, and other bodily processes that are not under conscious control.
Overall, the nervous system is a complex and intricate system that plays a critical role in maintaining the body's homeostasis and overall well-being.
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Muscle spindles are proprioceptors that consist of intrafusal muscle fibers enclosed in a sheath (spindle). They run parallel to the extrafusal muscle fibers and act as receptors that provide information on muscle length and the rate of change in muscle length. The spindles are stretched when the muscle lengthens. This stretch causes the sensory neuron in the spindle to transmit an impulse to the spinal cord, where it synapses with alpha motor neurons. This causes activation of motor neurons that innervate the muscle. The muscle spindles determine the amount of contraction necessary to overcome a given resistance. When the resistance increases, the muscle is stretched further, and this causes spindle fibers to activate a greater muscle contraction.
The following power point presentation talks about neural control and coordination in humans. In this, we study about neurons, the conduction of nerve impulse, about Central Nervous System and also about sense organs
In biology, the classical doctrine of the nervous system determines that it is a highly complex part of an animal that coordinates its actions and sensory information by transmitting signals to and from different parts of its body. nervous system is your body's command center. Originating from your brain, it controls your movements, thoughts and automatic responses to the world around you. It also controls other body systems and processes, such as digestion, breathing and sexual development (puberty).
The nervous system helps in controlling and coordinating various activities of the human body. The three types of nerves, cranial nerves, spinal nerves and visceral nerves run through the body and help in sending and receiving messages in the form of electrical impulses.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
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