A nephrectomy is a surgical procedure to remove one or part of a kidney. The first successful nephrectomy was performed in 1869 in Germany. Laparoscopic nephrectomy, involving smaller incisions, was first performed in 1990. A nephrectomy removes the kidney through small incisions or one larger incision in the abdomen. It is used to treat severe kidney damage or diseases like cancer, infections, or cysts, and to donate a healthy kidney for transplantation. Risks include infection, bleeding, and kidney failure of the remaining kidney. Patients may experience pain and discomfort after surgery and should avoid strenuous activity during recovery.