The document discusses chromosomes and their link to cancer. It notes that aneuploidy, which is an abnormal number of chromosomes, is a common genetic change in cancer. Whole chromosomes can become exiled from the nucleus due to errors in cell division. These exiled chromosomes form their own membrane and micronucleus. Cancerous cells are then generated from cells containing these micronuclei. The presence of micronuclei introduces more genetic material and an incorrect number of chromosomes in the cell.

1. Pulverizad” chromosomes
linked to cancer?.
Sebastián Gómez Restrepo
Medicine student.
3RD Semester
Molecular biology

2. FOLDING.

3. FOLDING

4. Introduction.
The core plays a
paper very
important inside the
cell since it contains
all the genetic
information of the
human beings, the
above mentioned
information is
contained in
chromosomes which
genes determine
the function of the
biological systems.

5. “ Pulverized” chromosomes
linked to cancer?.
The presence of
an incorrect
number of
chromosomes
inside the cells
is the genetic
change more
common in the
cancer. The
above
mentioned
condition is
known like
aneuploidy.

6. “ Pulverized” chromosomes
linked to cancer?.
Entire
chromosomes
exiles end out of
the core, as result
of a fault in the
cellular division.
The above
mentioned
chromosomes are
located in other
places inside the cell,
creating his own
membrane and
forming this way a
microcore.

7. “ Pulverized” chromosomes
linked to cancer?.
 Cancerous
cells are
generated
from cells by
microcores.

8. “ Pulverized” chromosomes
linked to cancer?.
 Aneuploidy in cells occurs when there
is a micronucleus, the micronucleus
chromosome brings more to the
genetic load, and therefore gives a
wrong number of chromosomes in the
cell.

9. Personal coment:
 During the cellular division there
happen mistakes that can take
alterations as consequences in the
genome and likewise you are genomic
alterations to bring with it
manifestations of one without end of
diseases.

10. New clues to human deafness
found in mice.
 A gene known
as FGF20 is
associated
with
hereditary
deafness
family

11. New clues to human deafness
found in mice.
 inactivation of the
gene produces a
loss of outer hair
cells, a special
type of inner ear
sensory cells
responsible for
sound
amplification.

12. New clues to human deafness
found in mice.
 Mutations in the
FGF20 gene may
play a role in
human deafness. A
genetic region
known as DFNB71
has been
associated with
deafness in a
human family.

13. New clues to human deafness
found in mice.
 The FGF20 gene encodes a member
of a family of proteins known as
fibroblast growth factors. In general,
members of this family are known to
play an important role in embryonic
development, tissue maintenance and
wound healing.

14. Personal coment.
 The unactivation of the gene
does not have cerebral
implications, only it affects the
proliferation of the sound
receptor cells.

16. Medical utility.
Accelerating the
process of
mutation by drug
therapy may be
an alternative for
the treatment of
some tumors.

17. Medical utility.
Learn more
about the
erroneous
and
unbridled
cell division
opens up a
world of
possibilities
in the
treatment of
cancer.

18. Medical utility.
by devices that enable the
amplification of sound can replace the
outer hair cells and thus allow people
to hear.

19. Bibliography
 Pulverizad” chromosomes linked to
cancer?. Science daily. 2012 January
19
 New clues to human deafness found
in mice. Science daily. 2012 January
19.
 MARTINEZ S, LINA MARIA. Biología
molecular. 6 ed. Medellin; UPB. Fac.
de medicina 2011. p 31-36.

20. “Lo importante es saber, lo que los
demás no saben que sabes”: Umberto
Eco