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What is MITOSIS ?

THE PROCESS BY WHICH TWO NEW
NUCLEII ARE FORMED, PRECEDING
         CELL DIVISION.




  http://fairmanstudios.com/als.htm
PURPOSE OF MITOSIS:
TO PRODUCE TWO NEW NUCLEII WITH…

  - EXACTLY THE SAME KIND
            and
 - EXACTLY THE SAME NUMBER

    . . . OF CHROMOSOMES
     AS THE PARENT CELL.
http://www.dartmouth.edu/artsci/bio/cbbc/courses/bio4/bio4-lectures/theCell.html




    MITOSIS is
    about
    organizing and
    distributing
    CHROMOSOMES
INTERPHASE




http://iccbweb.med.harvard.edu/mitchisonlab/Pages/mt.html
interphase
 interphase
INTERPHASE is the
                                              normal lifetime of a
                                              cell, after being
                                              “born” by division,
                                              and before it divides
                                              itself.
                                              INTERPHASE is not
                                              a stage of mitosis !




Biological Science, a Molecular Approach.
BSCS Blue Version. Heath and Company, 1996.
INTERPHASE:

                                                            Gap 1




                                              Gap 2
                                                          S-phase

Biological Science, a Molecular Approach.
BSCS Blue Version. Heath and Company, 1996.
nucleolus (if any)
 still visible                                                                       INTERPHASE:

                                                                                    nuclear envelope
                                                                                    clearly visible

                                                                                            chromatin,
                                                                                            NO
                                                                                            chromosomes,
                                                                                            yet


http://www.fed.cuhk.edu.hk/~johnson/photomicrographs/mitosis/animal/animal_interphase.htm
INTERPHASE




Allium root tip

                   Coregonus blastula
PROPHASE


    http://www.itg.uiuc.edu/technology/atlas/structures/mitosis/prophase.htm
PROPHASE




                             J Nuclear membrane dissolves.
                             J Nucleolus disappears.
                             J Chromosomes form.
                             J Centrioles migrate & form spindle.
http://www.blc.arizona.edu/courses/181gh/Lectures_WJG.01/mitosis_F.01/mitosis.html
PROPHASE
                                                                  nuclear envelope
                                                                  disappears




  nucleolus
  disappears                                                       chromosomes
                                                                   become visible
http://www.ac-dijon.fr/pedago/svt/documents/mitose/prophase.gif
PROPHASE




Allium root tip    Coregonus blastula
METAPHASE




http://iccbweb.med.harvard.edu/mitchisonlab/Pages/mt.html
METAPHASE
                                                        chromatids

                                                                   spindle

                                                                        centriole




            http://www.chembio.uoguelph.ca/educmat/chm736/cycletx.htm




J chromatids line up on the equator.
METAPHASE
             TWO IDENTICAL COPIES OF ONE CHROMOSOME.




    THIS                                                             THIS
CHROMATID                                                        CHROMATID
 WILL SOON                                                        WILL SOON
  MOVE TO                                                          MOVE TO
NORTH POLE                                                       SOUTH POLE




                    http://genenlab.spoono.com/gnu/mandm.shtml
METAPHASE




Allium root tip   Coregonus blastula
ANAPHASE




http://www.univ-orleans.fr/SCIENCES/BIOCHIMIE/MMC/accueil.htm
ANAPHASE

                                                                                 J chromatids migrate
                                                                                    to each pole.




http://www.blc.arizona.edu/courses/181gh/Lectures_WJG.01/mitosis_F.01/mitosis.html
ANAPHASE

          early                                                        late




Conly Rieder http://www.wadsworth.org/BMS/SCBlinks/WEB_MIT2/HOME.HTM
ANAPHASE




Allium root tip   Coregonus blastula
TELOPHASE
TELOPHASE




J Chromosomes dissolve.
J Mitotic spindle dissolves.
J Nuclear membrane forms.
J New nucleoli form.
TELOPHASE



    ONE
 DAUGHTER                       ONE
  NUCLEUS                    DAUGHTER
 FORMS AT                     NUCLEUS
NORTH POLE                   FORMS AT
                 SPINDLE    SOUTH POLE
                APPARATUS
                DISSOLVES
TELOPHASE




early                                                              late

New nuclei form at
   the poles.                                                                 Cytokinesis
                                                                                begins.


          http://www.blc.arizona.edu/courses/181gh/Lectures_WJG.01/mitosis_F.01/mitosis.html
TELOPHASE




Allium root tip    Coregonus blastula
THE
  END
(can you determine which stages
              these
          cells are in?

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