THIS IS PDF FILE FOR MITOCHONDRIAL INHERITANCE IN YEAST

1. PRESENTATIONBY:-
AMBALI BISHNU PATRA
WITH GUIDANCE OF :-
DR. SANTOSH KUMAR ROUT
ON TOPIC:-
CYTOPLASMIC INHERITANCE WITH REFRENCE TO
MITOCHONDRIAL INHERITANCE IN YEAST.

2. CONTENT :
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3. Cytoplasmic inheritance
Cytoplasmic inheritance is the transmission of genes that
occurs outside of the nucleus.
In cytoplasmic inheritance characters of only one parent
transmitted to progeny (usually the female parent).
Genes governing the traits showing to cytoplasmic
inheritance .located in the cytoplasm called plasma genes.
It is found in most eukaryotes and is commonly known to
occur in cytoplasmic organelles. Such as mitochondria and
chloroplasts.

4. Mitochondrial inheritance
➢ Mitochondria is a double membrane bound cell
organel which is also know as the power house of
the cell. It produces energy for cell’s survival and
functioning of the cell.
➢It contains several respiratory enzymes.
➢It is semiautonomous or self-replicating organelle
As it contains its own circular DNA.

5. Plasma gens located on mitochondria are called as mt-
DNA.
Mitochondrial inheritance referred to the inheritance of
trait encoded in the mitochondrial genome.
Generally Mitochondria from female parents are
transmitted to the progeny.
So characters governed by the genes located on mt-DNA
shows cytoplasmic inheritance .
Some Examples are Saccharomyces cerevisiae (yeast),
Neurospora, Aspergillus.

6. Petite Mutations in Yeast
Petite Mutant first discovered in yeast.
Due to defect in respiratory chain, yeast are unable to
grow on media containing non-fermentable carbon
sources ( such as glycerol, ethanol ) , form small colonies
when grow in fermentable carbon sources (such as glucose).
Petite mutations can be induced using Verity of
mutagenes including DNA intercalating agents as well as
chemical can interfere with DNA synthesis in growing cell.

9. The peptite mutants of yeast are
of 3-types.
1)Segregational petite
2) Neutral petite
3)Suppressive petite

10. 1.SEGREGATIONAL PETITE.
Mutants are created by nuclear mutations and
exhibit mendelian segregation.

12. 2.NEUTRAL PETITE.
Neutral petite when crossed with wild type, then all
offsprings are wild type. It has inherited normal mt-
DNA from wild type parent which is replicated in the
offspring.

14. 3. SUPRESSIVE PETITES.
When petite and wild type are crossed, all the
offsprings are petite showing dominant behavior to
suppres wild type mitochondrial function .

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