Methods of Capsule Preparation
•
30 likes•13,424 views
This document discusses hard and soft gelatin capsules. Gelatin capsules enclose drug substances within soluble shells, usually made from gelatin derived from animal bones and hides. Hard gelatin capsules are prepared through dipping, spinning, drying, stripping and trimming processes. Soft gelatin capsules are manufactured using one of four methods: plate, rotary die, reciprocating die or Accogel machine. The document describes the soft gelatin capsule production process and lists common evaluation tests for capsules including weight variation, content uniformity, dissolution and disintegration.
Report
Share
Report
Share
Recommended
Capsule's
Capsules are solid dosage forms that contain a drug enclosed within a hard or soft soluble shell, usually made of gelatin. There are two main types: hard gelatin capsules, which consist of two pieces that are joined, and soft gelatin capsules, which have a soft, one-piece shell. Capsules offer benefits like being tasteless, odorless, and easy to administer, and allow for flexible dosing. However, some drugs are not suitable for capsules due to stability issues. Capsules are manufactured through various processes depending on the type, including dipping, spinning, drying, filling, and sealing. They must pass quality tests like weight variation and content uniformity testing.
Equipments for Pellets
This document discusses different techniques for pelletization, including extrusion-spheronization, fluid bed granulation, spray drying, and spray congealing. Extrusion-spheronization involves extruding the material through a screen to form rods, which are then rounded into spheres using a spheronization machine. Fluid bed granulation coats particles in a fluidized bed with sprayed binding liquid. Spray drying and spray congealing involve spraying melted or dissolved formulations into cooled air to form solid spheres.
capsules
Hard and soft gelatin capsules are two types of capsules used for drug delivery. Hard capsules contain dry ingredients and disintegrate quickly once swallowed. They are made by dipping pins in gelatin solutions to form two-piece shells. Soft capsules contain liquids or semi-solids and have plasticized gelatin shells that are manufactured using plate, rotary die, or reciprocating processes. Both types of capsules are evaluated for stability, content uniformity, and disintegration time.
Tablets formulation
This document provides information about tablets, including their formulation, design, manufacturing, types, advantages, and excipients. Tablets are solid oral dosage forms made by compressing powder mixtures into various shapes. They have advantages like precise dosing and ease of production. The document discusses different granulation and compression methods used in tablet manufacturing. It also describes common excipients like diluents, binders, disintegrants, lubricants and their functions in tablets.
Soft gelatin capsules
The presentation deals with a detailed study of soft gelatin capsules. this involves the production of soft gelatin capsule based on the importance of base adsorption factor and minim/gram factor. also quality control studies was also elaborated.
Soft Gelatin Capsules
This document defines soft gelatin capsules and describes their anatomy, manufacturing process, quality considerations, and types. Soft gelatin capsules have a soft gelatin shell containing liquids, suspensions, or semisolids. The shell is made of gelatin, plasticizer, and water. The content can be liquids, solutions, or suspensions. The manufacturing process involves making the gel and content mixtures, encapsulating using machinery, drying, inspecting, and packaging. Quality is ensured through ingredient and in-process testing and finished product testing. Vegicaps are an alternative animal-free soft capsule with a seaweed and starch shell.
capsule manufacturing defects.pptx
These defects can cause serious injury and harm. When this occurs, you should speak with our product liability attorneys in Denver. You may have a viable claim to file a product liability lawsuit against the negligent manufacturer.Capsules are solid dosage forms in which the drug substance is enclosed within either a hard or soft soluble shell. Generally the shells are formed from gelatin. The capsule may be regarded as “container” drug delivery system, which provides a tasteless/odorless dosage form without the need of a secondary coating step, as may be required for tablets.Capsules are one of the essential components of the pharmaceutical sector. They are mainly used to hold dry powder or little pellets of medication and are made using specific machinery and techniques. The capsule's production method entails pharmaceutically active ingredients, additives, and a cover. Every pharmaceutical business understands capsule manufacturing takes time, and the reason is the critical measures.
Capsules
Capsules are solid dosage forms that enclose the drug substance within a soluble shell or envelope, primarily for oral delivery. There are two main types: hard gelatin capsules that contain solid medicines, and soft gelatin capsules that contain liquid or semi-solid medicines. Hard gelatin capsules are manufactured through a dipping, spinning, drying, and joining process to form two-piece capsules. Soft gelatin capsules are produced through plate or rotary die processes that fill and seal liquid-filled shells simultaneously. Both types require drying and may be polished before storage.
Recommended
Capsule's
Capsules are solid dosage forms that contain a drug enclosed within a hard or soft soluble shell, usually made of gelatin. There are two main types: hard gelatin capsules, which consist of two pieces that are joined, and soft gelatin capsules, which have a soft, one-piece shell. Capsules offer benefits like being tasteless, odorless, and easy to administer, and allow for flexible dosing. However, some drugs are not suitable for capsules due to stability issues. Capsules are manufactured through various processes depending on the type, including dipping, spinning, drying, filling, and sealing. They must pass quality tests like weight variation and content uniformity testing.
Equipments for Pellets
This document discusses different techniques for pelletization, including extrusion-spheronization, fluid bed granulation, spray drying, and spray congealing. Extrusion-spheronization involves extruding the material through a screen to form rods, which are then rounded into spheres using a spheronization machine. Fluid bed granulation coats particles in a fluidized bed with sprayed binding liquid. Spray drying and spray congealing involve spraying melted or dissolved formulations into cooled air to form solid spheres.
capsules
Hard and soft gelatin capsules are two types of capsules used for drug delivery. Hard capsules contain dry ingredients and disintegrate quickly once swallowed. They are made by dipping pins in gelatin solutions to form two-piece shells. Soft capsules contain liquids or semi-solids and have plasticized gelatin shells that are manufactured using plate, rotary die, or reciprocating processes. Both types of capsules are evaluated for stability, content uniformity, and disintegration time.
Tablets formulation
This document provides information about tablets, including their formulation, design, manufacturing, types, advantages, and excipients. Tablets are solid oral dosage forms made by compressing powder mixtures into various shapes. They have advantages like precise dosing and ease of production. The document discusses different granulation and compression methods used in tablet manufacturing. It also describes common excipients like diluents, binders, disintegrants, lubricants and their functions in tablets.
Soft gelatin capsules
The presentation deals with a detailed study of soft gelatin capsules. this involves the production of soft gelatin capsule based on the importance of base adsorption factor and minim/gram factor. also quality control studies was also elaborated.
Soft Gelatin Capsules
This document defines soft gelatin capsules and describes their anatomy, manufacturing process, quality considerations, and types. Soft gelatin capsules have a soft gelatin shell containing liquids, suspensions, or semisolids. The shell is made of gelatin, plasticizer, and water. The content can be liquids, solutions, or suspensions. The manufacturing process involves making the gel and content mixtures, encapsulating using machinery, drying, inspecting, and packaging. Quality is ensured through ingredient and in-process testing and finished product testing. Vegicaps are an alternative animal-free soft capsule with a seaweed and starch shell.
capsule manufacturing defects.pptx
These defects can cause serious injury and harm. When this occurs, you should speak with our product liability attorneys in Denver. You may have a viable claim to file a product liability lawsuit against the negligent manufacturer.Capsules are solid dosage forms in which the drug substance is enclosed within either a hard or soft soluble shell. Generally the shells are formed from gelatin. The capsule may be regarded as “container” drug delivery system, which provides a tasteless/odorless dosage form without the need of a secondary coating step, as may be required for tablets.Capsules are one of the essential components of the pharmaceutical sector. They are mainly used to hold dry powder or little pellets of medication and are made using specific machinery and techniques. The capsule's production method entails pharmaceutically active ingredients, additives, and a cover. Every pharmaceutical business understands capsule manufacturing takes time, and the reason is the critical measures.
Capsules
Capsules are solid dosage forms that enclose the drug substance within a soluble shell or envelope, primarily for oral delivery. There are two main types: hard gelatin capsules that contain solid medicines, and soft gelatin capsules that contain liquid or semi-solid medicines. Hard gelatin capsules are manufactured through a dipping, spinning, drying, and joining process to form two-piece capsules. Soft gelatin capsules are produced through plate or rotary die processes that fill and seal liquid-filled shells simultaneously. Both types require drying and may be polished before storage.
Capsules
Capsules are solid dosage forms that enclose one or more active ingredients within a soluble shell, typically made of gelatin. There are two main types: hard-shelled capsules containing dry powders, and soft-shelled capsules used for oils. Capsules are manufactured through a process involving dipping pins in gelatin solutions to form the shells, drying, stripping from the pins, trimming, joining the cap and body portions, and polishing. Various sizes of empty capsules are commercially available. Capsules offer benefits like ease of swallowing and unit dosing but require specialized filling equipment for industrial production.
Solid dosage forms (capsules)
This document discusses solid dosage forms known as capsules. It defines capsules as solid dosage forms where the drug is enclosed in a soluble shell, most commonly made of gelatin. There are two main types of capsules: hard gelatin capsules for solids and soft gelatin capsules for liquids. The document outlines the advantages and disadvantages of capsules, as well as methods for filling and evaluating different capsule types.
Pellets
A comprehensive interpretation of pellets based on their definitions, advantages, disadvantages, mechanism of pellet formation and growth, pelletization techniques, formulation requirements, and the equipment system for manufacture of pellets.
Hard gelatin capsules ppt B
Hard gelatin capsules are two-piece capsules consisting of a cap and body. They are manufactured through a dipping, spinning, drying, stripping, trimming and polishing process. The shell contains gelatin, dyes, opacifiers, plasticizers and preservatives. Capsules are filled using machines that separate the caps from bodies, fill the bodies with powders or granules, replace the caps and seal the capsule. Quality control tests include size, shape, content uniformity and dissolution. Capsules provide advantages like easy swallowing, taste masking and compatibility of multiple active ingredients.
Capsules
This document provides a summary of capsules, including their history, types, manufacturing process, evaluation, and key details. It discusses how gelatin capsules were first developed in the 18th century and how production methods have advanced. The main types - hard gelatin capsules, soft gelatin capsules, and their composition, sizes, and manufacturing processes - are outlined. Methods for evaluating capsules like uniformity of weight, drug content testing, disintegration testing, and dissolution testing are also summarized.
Parenterals
The document discusses parenterals, which are sterile preparations intended for administration through layers of skin or mucous membranes. It defines parenterals and outlines their advantages like 100% bioavailability and ability to administer to unconscious patients. The document also discusses the various routes of parenteral administration, types of parenterals like powders, solutions, and emulsions. It describes the formulation, layout, and quality control testing of parenterals. Specifically, it provides details on the areas involved in parenteral production, types of small and large volume parenterals, and common quality tests like leaker, clarity, pyrogenic, sterility, and content uniformity testing.
LIQUID ORALS INDUSTRIAL PHARMACY
Liquid oral topic in Industrial Pharmacy contains many topics like solution, elixirs, syrups, emulsion, and suspension. This topic includes general introduction, types, formulation, components, uses, and Quality control tests. These are also beneficial in other subjects like Pharmaceutics.
Tablets
A detailed study on tablets, its classification, excipients, tablet granulation, methods of granulation, compression machines, equipment tooling and the problems that occur during the tablet manufacturing process. This presentation is based on the PCI syllabus for bpharm students of fifth semester.
Pharmaceutical aerosols
Pharmaceutical aerosols are therapeutic active ingredients packaged in a pressurized system. They have advantages like direct delivery to affected areas without contamination. Aerosols consist of a propellant, container, valve, and product concentrate. Common propellants include hydrocarbons and gases. Containers must withstand high pressure and are often metal or glass. Valves meter doses and come in types like spray or foam. Formulations contain an active ingredient and propellant to achieve desired properties. Quality is ensured through testing of components, dosage, leakage and other parameters.
parenteral dosage form
The document discusses parenteral dosage forms. Parenterals are sterile solutions or suspensions of drugs administered directly into veins, muscles, or under the skin. They do not utilize the alimentary canal and must meet general requirements including stability, sterility, isotonicity, and being free of pyrogens, toxins, and foreign particles. Evaluation tests for parenterals include sterility, pyrogen, clarity, and leakage tests.
Hard Gelatin Capsule & Soft Gelatin Capsule
This document discusses hard and soft gelatin capsules. It defines capsules as solid dosage forms where the drug substance is enclosed within soluble gelatin shells. Hard gelatin capsules consist of two pieces (cap and body) while soft gelatin capsules have a single flexible shell. The document describes the production process for hard capsules including dipping, drying, and filling steps. It also discusses advantages like taste masking and disadvantages like incompatibility with hygroscopic drugs. Quality control tests for capsules include disintegration, weight variation, and dissolution testing.
Parenteral Products
The document discusses parenteral products and their administration. It defines parenteral as referring to administration by injection rather than orally, bypassing the gastrointestinal tract. It then discusses the advantages and disadvantages of the parenteral route, including faster systemic delivery but also risks of infection. The document outlines various routes of parenteral injection and provides details on procedures like subcutaneous, intramuscular, and intravenous injection. It also discusses formulation, processing, and quality testing of parenteral products.
Tablet Granulation Process by Gaurav Kumar Sharma
Granulation process may be defined as a process wherein small particles adhere together by forming bonds between them , resulting in the formation of large aggregates called granules.
Capsules classification and manufacture
DEFINITION
Capsules are solid preparations with hard and soft shells of various shapes and capacities, usually containing a single dose of active ingredients.
Manufacture of soft gelatin capsule
Soft gelatin capsules (SGCs) are hermetically sealed capsules containing liquids or semisolids without air. They are made of flexible gelatin and have gained popularity due to increased bioavailability of drugs and stability. Common manufacturing methods are rotary die and reciprocating die processes, which use gelatin ribbons to encapsulate fills. The rotary die process is most common, using rollers to converge ribbons around fills to seal and cut capsules continuously.
Capsule
Capsules can be hard or soft gelatin shells containing medications. Hard capsules have 13-16% moisture and are easier to swallow than soft capsules with over 16% moisture. Capsules offer benefits like precise dosing and packaging but may be difficult for some to swallow. They are manufactured by dipping plates in gelatin solutions to form shells, filling powder or liquid into the shells, and sealing. Quality is ensured through testing size, dissolution, and content uniformity during production.
Preformulation Studies
Preformulation studies characterize the physical and chemical properties of drug molecules to develop safe, effective, and stable dosage forms. The goals are to develop formulations that are stable, safe, and effective. Major areas of study include physical characterization of properties like crystallinity and polymorphism, hygroscopicity, particle size, and powder flow. Solubility is analyzed through measurements of ionization, partition coefficient, aqueous solubility, and pH-solubility profiles. Stability is analyzed through studies of photolytic stability, stability to oxidation, and drug-excipient compatibility.
Tablet Evaluation
The document discusses the evaluation and testing of tablets. It describes non-official tests like general appearance, organoleptic properties, size and shape, hardness, and friability. It also describes official tests like weight variation, content uniformity, dissolution, and disintegration. It discusses different types of tablets like compressed and molded tablets. It provides details on evaluating the appearance, hardness, friability and other properties of tablets and describes tests like weight variation, content uniformity, and dissolution used to ensure tablets meet specifications.
Tablet
This document provides an overview of tablet formulation and manufacturing. It discusses the definition and advantages of tablets as a popular dosage form. It describes different types of tablets including compressed, enteric coated, and chewable tablets. The document outlines the manufacturing process for compressed tablets including preparation of granules through wet and dry granulation. It also discusses common excipients used in tablet formulations such as diluents, binders, and lubricants. Finally, it provides information on tablet coating techniques and quality evaluation tests for tablets.
Preformulation Studies
The document discusses preformulation studies, which involve characterizing the physical and chemical properties of a drug substance before developing a dosage form. The goals are to generate stability-indicating parameters and select an appropriate dosage form. Key topics covered include the physical properties tested (such as solubility, polymorphism, particle size), chemical degradation pathways (such as hydrolysis, oxidation), and how these properties influence dosage form design and drug performance. Understanding a drug's preformulation behavior is critical for developing a safe, effective, and stable drug product.
Capsule
Capsules can be either hard gelatin or soft gelatin shells enclosing solid or liquid drugs. Hard gelatin capsules consist of two pieces - a body and cap - and contain powders, while soft gelatin capsules are one-piece and hermetically sealed, containing liquids. Capsules offer benefits like being tasteless, odorless, easy to administer and swallow, and allow flexible dosing. They also protect unstable drugs and allow combination therapies. However, hygroscopic and concentrated solutions may not be suitable for capsules. Capsules are manufactured through various processes including dipping, spinning, drying, filling, and sealing. Quality tests evaluate weight variation, content uniformity, dissolution, and disintegration
Illustration of the manufacturing process of hard gelatin capsule shell form ...
Illustration of the manufacturing process of hard gelatin capsule shell form ...MD. Mehedi Hasan Shawon
In this document i tried to give information about manufacturing process and shell form of hard gelatin capsule. i hope it will help you a lot.More Related Content
What's hot
Capsules
Capsules are solid dosage forms that enclose one or more active ingredients within a soluble shell, typically made of gelatin. There are two main types: hard-shelled capsules containing dry powders, and soft-shelled capsules used for oils. Capsules are manufactured through a process involving dipping pins in gelatin solutions to form the shells, drying, stripping from the pins, trimming, joining the cap and body portions, and polishing. Various sizes of empty capsules are commercially available. Capsules offer benefits like ease of swallowing and unit dosing but require specialized filling equipment for industrial production.
Solid dosage forms (capsules)
This document discusses solid dosage forms known as capsules. It defines capsules as solid dosage forms where the drug is enclosed in a soluble shell, most commonly made of gelatin. There are two main types of capsules: hard gelatin capsules for solids and soft gelatin capsules for liquids. The document outlines the advantages and disadvantages of capsules, as well as methods for filling and evaluating different capsule types.
Pellets
A comprehensive interpretation of pellets based on their definitions, advantages, disadvantages, mechanism of pellet formation and growth, pelletization techniques, formulation requirements, and the equipment system for manufacture of pellets.
Hard gelatin capsules ppt B
Hard gelatin capsules are two-piece capsules consisting of a cap and body. They are manufactured through a dipping, spinning, drying, stripping, trimming and polishing process. The shell contains gelatin, dyes, opacifiers, plasticizers and preservatives. Capsules are filled using machines that separate the caps from bodies, fill the bodies with powders or granules, replace the caps and seal the capsule. Quality control tests include size, shape, content uniformity and dissolution. Capsules provide advantages like easy swallowing, taste masking and compatibility of multiple active ingredients.
Capsules
This document provides a summary of capsules, including their history, types, manufacturing process, evaluation, and key details. It discusses how gelatin capsules were first developed in the 18th century and how production methods have advanced. The main types - hard gelatin capsules, soft gelatin capsules, and their composition, sizes, and manufacturing processes - are outlined. Methods for evaluating capsules like uniformity of weight, drug content testing, disintegration testing, and dissolution testing are also summarized.
Parenterals
The document discusses parenterals, which are sterile preparations intended for administration through layers of skin or mucous membranes. It defines parenterals and outlines their advantages like 100% bioavailability and ability to administer to unconscious patients. The document also discusses the various routes of parenteral administration, types of parenterals like powders, solutions, and emulsions. It describes the formulation, layout, and quality control testing of parenterals. Specifically, it provides details on the areas involved in parenteral production, types of small and large volume parenterals, and common quality tests like leaker, clarity, pyrogenic, sterility, and content uniformity testing.
LIQUID ORALS INDUSTRIAL PHARMACY
Liquid oral topic in Industrial Pharmacy contains many topics like solution, elixirs, syrups, emulsion, and suspension. This topic includes general introduction, types, formulation, components, uses, and Quality control tests. These are also beneficial in other subjects like Pharmaceutics.
Tablets
A detailed study on tablets, its classification, excipients, tablet granulation, methods of granulation, compression machines, equipment tooling and the problems that occur during the tablet manufacturing process. This presentation is based on the PCI syllabus for bpharm students of fifth semester.
Pharmaceutical aerosols
Pharmaceutical aerosols are therapeutic active ingredients packaged in a pressurized system. They have advantages like direct delivery to affected areas without contamination. Aerosols consist of a propellant, container, valve, and product concentrate. Common propellants include hydrocarbons and gases. Containers must withstand high pressure and are often metal or glass. Valves meter doses and come in types like spray or foam. Formulations contain an active ingredient and propellant to achieve desired properties. Quality is ensured through testing of components, dosage, leakage and other parameters.
parenteral dosage form
The document discusses parenteral dosage forms. Parenterals are sterile solutions or suspensions of drugs administered directly into veins, muscles, or under the skin. They do not utilize the alimentary canal and must meet general requirements including stability, sterility, isotonicity, and being free of pyrogens, toxins, and foreign particles. Evaluation tests for parenterals include sterility, pyrogen, clarity, and leakage tests.
Hard Gelatin Capsule & Soft Gelatin Capsule
This document discusses hard and soft gelatin capsules. It defines capsules as solid dosage forms where the drug substance is enclosed within soluble gelatin shells. Hard gelatin capsules consist of two pieces (cap and body) while soft gelatin capsules have a single flexible shell. The document describes the production process for hard capsules including dipping, drying, and filling steps. It also discusses advantages like taste masking and disadvantages like incompatibility with hygroscopic drugs. Quality control tests for capsules include disintegration, weight variation, and dissolution testing.
Parenteral Products
The document discusses parenteral products and their administration. It defines parenteral as referring to administration by injection rather than orally, bypassing the gastrointestinal tract. It then discusses the advantages and disadvantages of the parenteral route, including faster systemic delivery but also risks of infection. The document outlines various routes of parenteral injection and provides details on procedures like subcutaneous, intramuscular, and intravenous injection. It also discusses formulation, processing, and quality testing of parenteral products.
Tablet Granulation Process by Gaurav Kumar Sharma
Granulation process may be defined as a process wherein small particles adhere together by forming bonds between them , resulting in the formation of large aggregates called granules.
Capsules classification and manufacture
DEFINITION
Capsules are solid preparations with hard and soft shells of various shapes and capacities, usually containing a single dose of active ingredients.
Manufacture of soft gelatin capsule
Soft gelatin capsules (SGCs) are hermetically sealed capsules containing liquids or semisolids without air. They are made of flexible gelatin and have gained popularity due to increased bioavailability of drugs and stability. Common manufacturing methods are rotary die and reciprocating die processes, which use gelatin ribbons to encapsulate fills. The rotary die process is most common, using rollers to converge ribbons around fills to seal and cut capsules continuously.
Capsule
Capsules can be hard or soft gelatin shells containing medications. Hard capsules have 13-16% moisture and are easier to swallow than soft capsules with over 16% moisture. Capsules offer benefits like precise dosing and packaging but may be difficult for some to swallow. They are manufactured by dipping plates in gelatin solutions to form shells, filling powder or liquid into the shells, and sealing. Quality is ensured through testing size, dissolution, and content uniformity during production.
Preformulation Studies
Preformulation studies characterize the physical and chemical properties of drug molecules to develop safe, effective, and stable dosage forms. The goals are to develop formulations that are stable, safe, and effective. Major areas of study include physical characterization of properties like crystallinity and polymorphism, hygroscopicity, particle size, and powder flow. Solubility is analyzed through measurements of ionization, partition coefficient, aqueous solubility, and pH-solubility profiles. Stability is analyzed through studies of photolytic stability, stability to oxidation, and drug-excipient compatibility.
Tablet Evaluation
The document discusses the evaluation and testing of tablets. It describes non-official tests like general appearance, organoleptic properties, size and shape, hardness, and friability. It also describes official tests like weight variation, content uniformity, dissolution, and disintegration. It discusses different types of tablets like compressed and molded tablets. It provides details on evaluating the appearance, hardness, friability and other properties of tablets and describes tests like weight variation, content uniformity, and dissolution used to ensure tablets meet specifications.
Tablet
This document provides an overview of tablet formulation and manufacturing. It discusses the definition and advantages of tablets as a popular dosage form. It describes different types of tablets including compressed, enteric coated, and chewable tablets. The document outlines the manufacturing process for compressed tablets including preparation of granules through wet and dry granulation. It also discusses common excipients used in tablet formulations such as diluents, binders, and lubricants. Finally, it provides information on tablet coating techniques and quality evaluation tests for tablets.
Preformulation Studies
The document discusses preformulation studies, which involve characterizing the physical and chemical properties of a drug substance before developing a dosage form. The goals are to generate stability-indicating parameters and select an appropriate dosage form. Key topics covered include the physical properties tested (such as solubility, polymorphism, particle size), chemical degradation pathways (such as hydrolysis, oxidation), and how these properties influence dosage form design and drug performance. Understanding a drug's preformulation behavior is critical for developing a safe, effective, and stable drug product.
What's hot (20)
Similar to Methods of Capsule Preparation
Capsule
Capsules can be either hard gelatin or soft gelatin shells enclosing solid or liquid drugs. Hard gelatin capsules consist of two pieces - a body and cap - and contain powders, while soft gelatin capsules are one-piece and hermetically sealed, containing liquids. Capsules offer benefits like being tasteless, odorless, easy to administer and swallow, and allow flexible dosing. They also protect unstable drugs and allow combination therapies. However, hygroscopic and concentrated solutions may not be suitable for capsules. Capsules are manufactured through various processes including dipping, spinning, drying, filling, and sealing. Quality tests evaluate weight variation, content uniformity, dissolution, and disintegration
Illustration of the manufacturing process of hard gelatin capsule shell form ...
Illustration of the manufacturing process of hard gelatin capsule shell form ...MD. Mehedi Hasan Shawon
In this document i tried to give information about manufacturing process and shell form of hard gelatin capsule. i hope it will help you a lot.softgelatincapsule-150816041330-lva1-app6892.pdf
Capsules are solid dosage forms that contain medication and are intended for oral administration. They have hard or soft shells made of gelatin or other substances. Soft gelatin capsules (softgels) are one-piece, hermetically sealed capsules containing liquids, suspensions, or semisolids. They are produced using either a droplet method, where drops of gelatin and medication are cooled and solidified, or a pressing method, where a gelatin ribbon is shaped and filled in a mold. Softgels offer benefits like improved drug stability and bioavailability compared to other capsule types and can be colored, shaped, coated, and flavored.
Soft gelatin capsule
This document discusses soft gelatin capsules. Soft gelatin capsules have soft, gelatin shells that contain liquid or semisolid fill materials. They are formed, filled, and sealed in a single operation using either a droplet or pressing method. Soft gelatin capsules offer advantages over hard capsules like improved bioavailability and enhanced stability. The shells are made of gelatin, plasticizers, preservatives, colors and flavors. Soft gelatin capsules can be used orally or for other routes of administration.
Capsule
Its All About Capsule...
i tried to explain in short...
hope you liked it..
please like and share to all students,
which are want to more study in minimum time..
Thank You..
also join on whatsapp to bring newthings
contact no. 9765763626
capsules.pptx
This document discusses capsules as a dosage form for drug delivery. It defines capsules as solid dosage forms where the drug is enclosed in a soluble shell or envelope. There are two main types: hard gelatin capsules and soft gelatin capsules. Hard gelatin capsules contain powders, granules or beads and consist of two pieces that are filled and joined. Soft gelatin capsules contain liquids or suspensions and form a single shell that is filled during manufacturing. Capsules offer advantages like masking taste and odor, ease of swallowing and portability, but also have limitations like being unsuitable for hygroscopic or concentrated drugs. The document outlines the production process, properties of fill materials, applications and differences between the
Soft and hard gelatin capsules
Capsules are tasteless, odorless and can easily be
administered.
Combination of powders we can use
There are attractive in appearance.
The drugs having un-pleasant odor and taste are
enclosed in a tasteless shell.
They can be filled quickly and conveniently.
Physician can change the dose and combination of drug
according to patient requirement.
They are economical.
They are easy to handle and carry.
Manufacturing of capsule
Capsules are solid dosage forms that enclose medicinal agents or inert substances within a shell made of gelatin. There are two main types of capsules: hard gelatin capsules and soft gelatin capsules. Hard gelatin capsules have two pieces (body and cap) that are manufactured using molds, while soft gelatin capsules are produced using one of two processes - a plate process or rotary die process - that form the capsule as a single unit. The manufacturing of capsules involves precise control of parameters like gelatin viscosity, drying time and temperature to produce uniform capsules of the desired size, shape and quality.
Capsules
Capsules: Hard and Soft ccapsules, Raw materials, Production of ccapsules, Filling, Evaluation of capsules
Capsules
Capsules are solid dosage forms that enclose drug substances within hard or soft soluble shells, usually made of gelatin. There are two main types - hard gelatin capsules, which have two pieces, and soft gelatin capsules, which are one-piece and hermetically sealed. Capsules offer advantages like being tasteless, odorless, and easy to administer, and allow for flexible dosing. Key steps in production include dipping, spinning, drying, stripping, trimming, joining, and filling. Capsules are evaluated for weight variation, content uniformity, and dissolution.
Pdf seminar final
Hard and soft gelatin capsules are commonly used solid oral dosage forms. Recent advancements include non-gelatin capsules made from HPMC or starch which provide alternatives for people with gelatin allergies. The manufacturing process for hard gelatin capsules involves dipping pins in gelatin solution to form shells, drying the shells, stripping them from the pins, trimming, joining, and polishing. Soft gelatin capsules are manufactured using various processes like plate, rotary die, or reciprocating die methods. Quality control checks are performed during manufacturing and evaluation includes testing for stability, content uniformity, disintegration, and dissolution.
Solid dosages forms ( capsules)
This document discusses capsules as a pharmaceutical dosage form. It defines capsules as solid dosage forms where the drug is enclosed in a soluble shell, usually made of gelatin. There are two main types of capsules: hard gelatin capsules which contain powders, and soft gelatin capsules which contain liquids. The document describes the components, manufacturing process, filling, and evaluation of both hard and soft gelatin capsules. It also discusses the advantages and disadvantages of capsules as a dosage form.
Processing of capsule
Capsules are a solid dosage form with a drug substance enclosed in a water soluble shell made of gelatin. They come in both hard and soft forms. Capsules have advantages like masking unpleasant tastes and smells, allowing sustained release, and being economical and easy to handle. However, hygroscopic drugs cannot be filled in capsules as they may absorb water and break. Capsules come in various standard sizes depending on their capacity. Soft gelatin capsules can have different shapes and their contents include liquids or solids dissolved in excipients to form a paste. They are sealed during the combined filling and sealing operation on machines.
Capsule
Capsules are solid dosage forms that enclose the drug substance within a soluble shell, usually made of gelatin. There are two main types: hard gelatin capsules and soft gelatin capsules. Hard capsules have a two-piece shell and are made through a dipping and drying process to form the capsule halves, which are then trimmed, joined, and polished. They can encapsulate various solid and semisolid drugs. Soft capsules have an outer shell surrounding a liquid or semisolid inner fill and provide various advantages over traditional capsules like easy swallowing and improved bioavailability.
Capsules
This document discusses different types of gelatin capsules used in pharmaceutical formulations. It describes hard gelatin capsules which are made of two pieces that are joined together, and soft gelatin capsules which contain more moisture and are used to encapsulate liquid drugs. The key types are discussed, including their composition, manufacturing process, advantages, and packaging. Hard gelatin capsules can be filled with solids or semisolids while soft gelatin capsules are used for liquid fill formulations.
Capsules
Solid unit dosage forms the drug is enclosed within the water-soluble shell or an envelope either a hard or soft shell. Shell is typically made of gelatin primarily intended for oral delivery and provides a rapid release of contents.
Generally, the shells are formed from gelatin.
Capsule
This document provides information about hard gelatin capsules, including their introduction, advantages, disadvantages, raw materials, manufacturing process, sizes, properties of filled materials, filling equipment, and evaluation standards. It discusses that hard capsules consist of two pieces (cap and body) made of gelatin, and are filled with powders. The key steps in manufacturing include dipping molds in hot gelatin solution, drying, stripping, trimming, and joining. Capsules range in size from 000 to 5 and are evaluated based on parameters like weight variation, content uniformity, and dissolution testing. Common filling equipment includes Rotosort, Rotofill, and Accogel.
Capsule
define capsules, types, processing , special types,offical test of capsules, storage & labelling of capsules
Capsules2
The document provides information about capsules, including definitions, history, types (hard capsules, soft gelatin capsules, microencapsulation), and methods of preparation. It discusses the key components of capsules (gelatin, colorants, preservatives), as well as the processes involved in manufacturing hard and soft gelatin capsules. The summary highlights the document's focus on capsules as a solid dosage form where active ingredients are enclosed in gelatin shells for oral administration, and methods for filling capsules with various materials like powders, semisolids, and liquids.
Capsule
Capsules are solid dosage forms that contain medicaments enclosed in a gelatin shell. They have several advantages over tablets such as easier swallowing, masking of unpleasant tastes, and faster onset of action. There are two main types - hard gelatin capsules which contain powders and soft gelatin capsules which contain liquids. Hard gelatin capsules consist of a body and cap section and can be filled by hand or machine. Soft gelatin capsules are manufactured using various processes and contain liquid medications within a plasticized gelatin shell. Capsules are commonly evaluated based on weight variation, content uniformity, and disintegration or dissolution testing.
Similar to Methods of Capsule Preparation (20)
Illustration of the manufacturing process of hard gelatin capsule shell form ...
Illustration of the manufacturing process of hard gelatin capsule shell form ...
More from Abdullah Al Mubin
Parturition process in mare and buffalo
This document discusses the parturition (birthing) process in mares and buffalo, dividing it into three stages. For mares, stage one involves restlessness, stage two begins with rupture of fetal membranes and ends with fetal expulsion over 15-30 minutes, and stage three expels the fetal membranes over 3 hours. For buffalo, stage one lasts 1-12 hours with behavioral changes, stage two lasts 45-90 minutes and ends with fetal expulsion, and stage three expels fetal membranes over 7-12 hours. Understanding parturition helps livestock breeders identify and address problems.
Breeding Soundness Evaluation in Female Animal by Rectal Palpation and Ultras...
This document summarizes a presentation on breeding soundness evaluation of female animals through rectal palpation and ultrasonography. The presentation covers the importance of breeding soundness evaluation to identify healthy animals for breeding programs. It describes evaluating the cervix, uterus, ovaries, and other structures by rectal palpation and using ultrasonography. Ultrasonography allows viewing images of the corpus luteum, endometrium, follicular cysts, luteal cysts, pyometra, and endometritis. The conclusion states that breeding soundness evaluation is important for farm economy by allowing selection of healthy dams that can produce healthy offspring.
Technique of Taking Biopsy from Endometrium and Interpretation
This document discusses the technique of taking a biopsy from the endometrium and interpreting the results. It begins by outlining the objectives and requirements for taking an endometrial biopsy. The technique is then described in 7 steps and involves using a uterine biopsy catheter to collect a small piece of tissue from the lining of the uterus. Finally, the document discusses how to interpret the biopsy results by examining the tissue sample for conditions like periglandular fibrosis, cystic glandular changes, and cellular infiltration of the endometrium.
Benzimidazoles
Benzimidazoles are heterocyclic organic compounds used to treat infections from roundworms, tapeworms, lungworms, and liver flukes. They act by uncoupling oxidative phosphorylation in flukes, inhibiting the fumarate reductase enzyme and impairing glucose uptake, decreasing ATP synthesis and killing the parasite. Common drugs include albendazole, fenbendazole, and triclabendazole, which are dosed based on species and weight. Side effects can include headaches, nausea, and vomiting, while rare but serious effects include acute renal failure and hepatotoxicity. Benzimidazoles are contraindicated during pregnancy, lactation, or for hypersensitive or younger animals.
Antibiotic Resistance
This document discusses antibiotic resistance, its causes, mechanisms, and prevention. It defines antibiotic resistance as the ability of bacteria and other microorganisms to withstand antibiotics to which they were once sensitive. The main causes listed are misuse and overuse of antibiotics, incomplete treatment courses, and unnecessary antibiotic use in veterinary medicine. Mechanisms of resistance include blocking entry, drug inactivation, altering target sites, and efflux of antibiotics. Prevention efforts should focus on controlling misuse, restricting self-medication, and ensuring full treatment courses.
Solid Form of Drug
This presentation discusses solid forms of drugs for administration. It describes tablets, capsules, sugar coated capsules, powder and granules as the main solid drug forms. Tablets are solid dosages made by compressing or molding drugs and come in various types depending on how they are administered or released. Capsules contain drugs in a gelatin shell. Powder and granules are important for formulating other solid drugs. The advantages of solid drug forms are convenience, accurate dosing, stability and mass production.
Aminoglycosides Used in Veterinary Practice
Aminoglycosides are a class of traditional antibiotics that inhibit protein synthesis in gram-negative bacteria. Examples include streptomycin, gentamicin, neomycin, and tobramycin. They act by binding to the bacterial ribosome and inhibiting protein synthesis. They can be administered intravenously, intramuscularly, orally, or topically. They are used to treat infections caused by gram-negative bacteria, including complicated urinary tract infections, skin infections, abdominal infections, and tuberculosis. However, they are contraindicated in patients with mitochondrial disorders due to the risk of hearing loss, tinnitus, cardiac toxicity, and renal toxicity. Common adverse effects include inner ear toxicity, vestibular damage
Theileriosis(Drug Choice)
This document discusses drug choice for treating theileriosis, a protozoan disease of cattle. Buparvaquone is identified as the specific drug against theileriosis, as it is effective against both schizont and piroplasm stages of the disease-causing parasites Theileria. Buparvaquone works by inhibiting the mitochondrial electron transport system of the protozoa, affecting their energy generation and causing death. It has a bioavailability of approximately 3% when given by intramuscular injection, a half-life of 26.44 hours, and is usually excreted through urine. The recommended dose is 2.5 mg/kg body weight administered intramuscularly, with
Semen Evaluation
This document discusses semen evaluation in animals. It defines semen as the liquid containing sperm and seminal plasma ejected from the male reproductive tract. Regular examination of semen is important for assessing breeding soundness, infertility, artificial insemination, and parasitic diseases. The document outlines the microscopic and macroscopic parameters examined during semen evaluation, including volume, color, motility, sperm concentration, and the presence of abnormalities. Normal semen values are provided for various species.
Prostate hyperplasia in Dog
Prostate hyperplasia in dogs is a natural consequence of aging that occurs in most dogs over six years old, as both estrogen and androgen must be present for marked enlargement. The prostate gland is located near the bladder, and an enlarged prostate can be detected during rectal examination, ultrasound, or cytological examination. The most effective treatments are castration to cause involution of the enlarged gland or low dose estrogen treatment to depress hormone secretion.
Paraphimosis in Cattle
Paraphimosis in bulls occurs when the penis becomes trapped outside the prepuce and cannot be retracted. It is usually caused by erection after semen collection or mating due to swelling. Clinical signs include an edematous, desiccated, and painful unexposed penis. Treatment involves gentle cleansing and lubrication followed by slowly replacing the penis inside the prepuce to restore circulation. If swelling does not resolve, amputation of the penis may be necessary.
Granular Vulvovaginitis in Cattle
Granular vulvovaginitis is an infectious disease of the vulva and vagina characterized by the development of small elevated pustules or granules, which are more commonly found on the vulva than in the vagina. It can be caused by bacteria like Streptococcus and Gardnerella, yeast like Candida albicans, viruses like BHV-1, parasites, trichomoniasis, environmental factors, allergens, or chemical irritants. Treatment involves flushing the area with antiseptics, using antibiotics or antifungals, and giving oral antihistamines if allergies are suspected.
Cronic Endometritis in Cow
This document defines and discusses endometritis, a condition where the endometrium (lining of the uterus) becomes inflamed. It outlines predisposing factors like retained placenta or difficult birth. The principal microorganisms involved are Actinomyces pyogenes and Fusobacterium necrophorum. Clinical signs include a white vaginal discharge and failure to conceive. Diagnosis involves history, examination, culture and biopsy. Treatment consists of intrauterine and parenteral antibiotics, hormonal therapy with estradiol and oxytocin, and supportive care like cleaning and balanced diet. Management focuses on keeping the animal in a hygienic environment.
Posthitis in bull
Posthitis is inflammation of the prepuce in bulls. It is caused by viruses, bacteria, molds, protozoa, or trauma. Clinical signs include swelling, pain, unwillingness to mate, preputial stenosis, and adhesion between the penis and prepuce. Diagnosis involves history, clinical signs, inspection and palpation of the prepuce, and bacteriological tests of swabs from the glans penis and prepuce. Treatment consists of irrigation with acriflavin, antibiotics, surgery if the prepuce is obstructed, pain killers, and antihistamines.
Orchitis in bull
Orchitis in a bull is an inflammation of the testes that causes painful swelling. It can be caused by trauma, infections from bacteria like Brucella abortus, or testicular torsion. Clinical signs include severe pain and swelling of the testes. Treatment includes cold water application, anti-inflammatory drugs, and antibiotics, but often the affected testes loses function and surgical removal is needed. The affected bull should be culled or given sexual rest to prevent spreading any infection.
Techniques of Artificial Insemination in Cow, Doe, Ewe and Chicken
This document discusses techniques for artificial insemination in various animal species. It begins by defining artificial insemination as the introduction of semen into the female reproductive tract by means other than sexual intercourse. Advantages include genetic improvement and disease control, while limitations include needing skilled personnel and lower conception rates than natural breeding. The techniques described include recto-vaginal insemination in cows, intravaginal or transcervical insemination in does, and various methods like intravaginal, transcervical, or laparoscopic intrauterine insemination in ewes. For chickens, semen is deposited into the vagina with the bird restrained and its abdomen pressed.
Egg and Cyst of Parasites Commonly found in Veterinary Teaching Hospital of BAU
This document provides instructions for microscopic examination of feces to identify common parasites. It lists the eggs or cysts of six parasites that can be seen under a microscope: Fasciola, Paramphistomum, Schistosoma, Balantidium coli, hookworm, and stomach worm. Identification of these parasites in feces can help diagnose infections.
More from Abdullah Al Mubin (17)
Breeding Soundness Evaluation in Female Animal by Rectal Palpation and Ultras...
Breeding Soundness Evaluation in Female Animal by Rectal Palpation and Ultras...
Technique of Taking Biopsy from Endometrium and Interpretation
Technique of Taking Biopsy from Endometrium and Interpretation
Techniques of Artificial Insemination in Cow, Doe, Ewe and Chicken
Techniques of Artificial Insemination in Cow, Doe, Ewe and Chicken
Egg and Cyst of Parasites Commonly found in Veterinary Teaching Hospital of BAU
Egg and Cyst of Parasites Commonly found in Veterinary Teaching Hospital of BAU
Recently uploaded
The Nervous and Chemical Regulation of Respiration
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
LOOPS in orthodontics t loop bull loop vertical loop mushroom loop stop loop
vertical loop
horizontal loop
The Electrocardiogram - Physiologic Principles
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
In some case, your chronic prostatitis may be related to over-masturbation. Generally, natural medicine Diuretic and Anti-inflammatory Pill can help mee get a cure.
vonoprazan A novel drug for GERD presentation
Vonoprazan, a new potassium acid channel blocker used in the conditions of GERD and gastric ulcer, duodenal ulcer ....
Part II - Body Grief: Losing parts of ourselves and our identity before, duri...
Learn about body grief and ways to cope with it. We will also explore methods to heal from this challenging experience.
Top Effective Soaps for Fungal Skin Infections in India
Swisschem Dermacare has mentioned the List of The Best Antifungal Soap In India 2022. All of these soaps are trusted by various Dermatology Experts.
Histopathology of Rheumatoid Arthritis: Visual treat
Histopathology of Rheumatoid Arthritis: Visual treat
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
Explore the benefits of combining Ayurveda with conventional Parkinson's treatments. Learn how a holistic approach can manage symptoms, enhance well-being, and balance body energies. Discover the steps to safely integrate Ayurvedic practices into your Parkinson’s care plan, including expert guidance on diet, herbal remedies, and lifestyle modifications.
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.Osteoporosis - Definition , Evaluation and Management .pdf
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
Histololgy of Female Reproductive System.pptx
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
Recently uploaded (20)
The Nervous and Chemical Regulation of Respiration
The Nervous and Chemical Regulation of Respiration
LOOPS in orthodontics t loop bull loop vertical loop mushroom loop stop loop
LOOPS in orthodontics t loop bull loop vertical loop mushroom loop stop loop
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
CHEMOTHERAPY_RDP_CHAPTER 6_Anti Malarial Drugs.pdf
CHEMOTHERAPY_RDP_CHAPTER 6_Anti Malarial Drugs.pdf
Part II - Body Grief: Losing parts of ourselves and our identity before, duri...
Part II - Body Grief: Losing parts of ourselves and our identity before, duri...
Top Effective Soaps for Fungal Skin Infections in India
Top Effective Soaps for Fungal Skin Infections in India
Histopathology of Rheumatoid Arthritis: Visual treat
Histopathology of Rheumatoid Arthritis: Visual treat
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
Tests for analysis of different pharmaceutical.pptx
Tests for analysis of different pharmaceutical.pptx
Osteoporosis - Definition , Evaluation and Management .pdf
Osteoporosis - Definition , Evaluation and Management .pdf
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
Methods of Capsule Preparation
- 1. NASRIN AKTER MUKTA Faculty of Veterinary Science Bangladesh Agricultural University
- 2. Introduction Hard gelatin capsule Soft gelatin capsule Evaluation of capsule
- 3. Capsules are solid dosage forms in which drug substance is enclosed within hard or soft soluble shell . The shells are generally formed from gelatin. Capsules are of two types 1.Hard gelatin capsules 2.Soft gelatin capsules
- 4. Gelatin is a heterogeneous product derived by hydrolytic extraction of animal’s collagen. The source of gelatin including animal bones , hide portions and frozen pork skin
- 5. Methods of preparation of hard gelatin capsule shells Dipping Spinning Drying Stripping Trimming Joining
- 6. Methods of preparation of capsule shell .
- 7. Developing and preparing formulation Filling the capsule shell Capsule sealing Cleaning and polishing the filled capsules
- 9. .
- 10. Is manufactured by four methods 1.Plate process 2.Rotary die process 3.Reciprocating die 4.Accogel machine
- 11. Liquid mixture is placed in one hopper and the liquid medicament in other hopper The two rotating dies rotate in opposite directions when the fluid gelatin mixture enters the machine from the hopper it produces two continuous ribbons
- 12. These half shell of the capsule is formed At this stage medicament is filled into it with the stroke of a pump with subsequent movement of the dies the other half capsule is formed The two halves of the capsules are sealed together by the heat and pressure of the rotating dies As the die rolls rotate , the matching die pocket seals and cuts out the filled capsules.
- 13. .
- 15. Weight variation test Content uniformity test Dissolution test Disintegration test