This document defines and discusses endometritis, a condition where the endometrium (lining of the uterus) becomes inflamed. It outlines predisposing factors like retained placenta or difficult birth. The principal microorganisms involved are Actinomyces pyogenes and Fusobacterium necrophorum. Clinical signs include a white vaginal discharge and failure to conceive. Diagnosis involves history, examination, culture and biopsy. Treatment consists of intrauterine and parenteral antibiotics, hormonal therapy with estradiol and oxytocin, and supportive care like cleaning and balanced diet. Management focuses on keeping the animal in a hygienic environment.

1. Presented by
Md.Habib Ullah
ID No. 1401078
Sec. A Group. D

2. OUTLINE
 Defination
 Predisposing factors
 Etiology
 Clinical signs
 Diagnosis
 Treatment
 Management

3. DEFINITION
ENDOMETRITIS
Inflammation of endometrium is called
endometritis.
CHRONIC ENDOMETRITIS
Chronic inflammation of endometrium is called
chronic endometritis

4. PREDISPOSING FACTORS
 Retained fetal membranes
 Dystocia
 Multiple birth
 Abortion
 Induced calving
 Unsanitary calving condition

5. ETIOLOGY
The principal micro-organisms associated with endometritis
are:
• Actinomyces pyogenes
• Fusobacterium necrophorum

6. CLINICAL SIGNS
 White or whitish-yellow
mucopurulent vaginal
discharge comes out
when a diseased cow sit
down.
 Copious mucopurulent
discharge at the time of
oestrus.
 No signs of systemic
illness like septic
puerperal metritis.

7. CLINICAL SIGNS
 Repeat breeding and failure of conception are the most
common symptoms of endometritis.

8. DIAGNOSIS
 History of the patient.
 Clinical signs.
 Rectal palpation.
 Endometrial culture and biopsy.
 White side test.
 Microscopic examination of the vaginal discharge.

9. TREATMENT
(1)Antimicrobial therapy:
Intrauterine route
• Penicillin: Intrauterine infusion of 10 to 15 lakhs IU of
penicillin in the lumen and entire wall of the uterus.
• Oxytetracycline: 2 gm daily for 3 to 5 days.
Parenteral administration
• Penicillins: 8,000-10,000 IU per kg. body weight at 24
hours intervals for 3-5 days deep IM route
• Oxytetracycline: 22 mg/kg IM

10. TREATMENT( continue)
(2)Hormonal therapy
(a) Oestradiol valerate: 3-10 mg IM. This treatment can
be repeated at an interval of 7 days if required.
(b) Oxytocin: 10-20 IU within 4-6 hours of the oestrogen
injection.
(c) PGF2α analogues: Vetmate 2 ml I/M
(3)Supportive therapy
• Levamisole@ 2.5 mg/ body weight i.e. 10-15ml s/c
• Mineral mixture containing vit. A , D & E helps in
regeneration of endometrium and enhanches immunity .

11. MANAGEMENT
 Animal should be kept in hygienic environment.
 Animal should be cleaned regularlly.
 Bedding material should be dry and clean.
 Balanced diet should be provided.
 Anal region should be kept dry and clean.

12. THANKS
TO
ALL