Anatomical localisation of function is a fundamental principle in the neurosciences. This presentation highlights the basics neuroanatomy and correlate major brain structure with their functions.
Anatomical localisation of function is a fundamental principle in the neurosciences. This presentation highlights the basics neuroanatomy and correlate major brain structure with their functions.
Here is anatomy and physiology of brain stem. Where we will discuss all three parts of brain stem. Starting from medulla, second is pons and third is mid brain. In this video I am presenting anatomy and physiology of medulla. Anatomy of medulla: Medulla Oblongata or more simply medulla is part of brain stem which forms base of the brain stem. Location of medulla oblongata is superior to spinal cord and inferior to Pons. It contains pyramid, olive and above pyramidal structure, there is decussation of pyramids which explains why each part of brain controls opposite part of body. Adding to that medulla also has several nuclei which controls activity of cardiovascular system and respiratory system. Medulla also has nuclei for controlling reflexes of vomiting, swallowing, hiccuping, coughing and sneezing. It has also nuclei for test, hearing and balance. Medulla also contains nuclei of cranial nerve number VIII, IX, X, XI and XII. Functions of medulla or what dose medulla do? So medulla controls blood pressure, diameter of wall of arteries, heart rate, basal respiration rate and also vomiting, swallowing, hiccuping, coughing and sneezing.
In this video, we explain you about anatomy and physiology of Pons. The reference material used to make video is: Principles of Anatomy and Physiology Gerard J. Tortora, Bryan H. Derrickson. Pons is part of brain stem, present superior to medulla, inferior to mid brain and anterior to cerebellum. Pons means a bridge. As the name denotes, it connects other areas of brain. Neurons extending from cerebral cortex to pons makes corticopontine tract. Pons is connected to cerebellum by middle cerebral peduncle. Pons has vestibular nuclei, which is part of equilibrium pathways from inner ear to brain. Pons has also respiratory nuclei. Along with rhythmicity area of medulla, pons controls basal respiratory rhythm. Pons also contains nuclei for cranial nerve number V, VI,VII, and VIII.
Anatomy of Human Brain Presented by Dr Arman MD (Resident) Physical Medicine & Rehabilitation, Dhaka Medical College, Dhaka, Bangladesh. reference taken from latest book & journal.
Here is anatomy and physiology of brain stem. Where we will discuss all three parts of brain stem. Starting from medulla, second is pons and third is mid brain. In this video I am presenting anatomy and physiology of medulla. Anatomy of medulla: Medulla Oblongata or more simply medulla is part of brain stem which forms base of the brain stem. Location of medulla oblongata is superior to spinal cord and inferior to Pons. It contains pyramid, olive and above pyramidal structure, there is decussation of pyramids which explains why each part of brain controls opposite part of body. Adding to that medulla also has several nuclei which controls activity of cardiovascular system and respiratory system. Medulla also has nuclei for controlling reflexes of vomiting, swallowing, hiccuping, coughing and sneezing. It has also nuclei for test, hearing and balance. Medulla also contains nuclei of cranial nerve number VIII, IX, X, XI and XII. Functions of medulla or what dose medulla do? So medulla controls blood pressure, diameter of wall of arteries, heart rate, basal respiration rate and also vomiting, swallowing, hiccuping, coughing and sneezing.
In this video, we explain you about anatomy and physiology of Pons. The reference material used to make video is: Principles of Anatomy and Physiology Gerard J. Tortora, Bryan H. Derrickson. Pons is part of brain stem, present superior to medulla, inferior to mid brain and anterior to cerebellum. Pons means a bridge. As the name denotes, it connects other areas of brain. Neurons extending from cerebral cortex to pons makes corticopontine tract. Pons is connected to cerebellum by middle cerebral peduncle. Pons has vestibular nuclei, which is part of equilibrium pathways from inner ear to brain. Pons has also respiratory nuclei. Along with rhythmicity area of medulla, pons controls basal respiratory rhythm. Pons also contains nuclei for cranial nerve number V, VI,VII, and VIII.
Anatomy of Human Brain Presented by Dr Arman MD (Resident) Physical Medicine & Rehabilitation, Dhaka Medical College, Dhaka, Bangladesh. reference taken from latest book & journal.
I am a Neurosurgeon with advanced training in Interventional vascular Neurosurgery(FINR) from Zurich, Switzerland, and FMINS-Fellowship in minimally invasive and Endoscopic Neurosurgery from Germany.
I am presently working in Columbia asia hospitals, Bangalore.
My areas of interest are Vascular Neurosurgery, Stroke specialist, interventional neuroradiology, Endoscopic and minimally invasive Neurosurgery, Endoscopic spine surgery.
Unit-I, Chapter_1 Nervous System Final PPT.pptAudumbar Mali
B. Pharm. Sem:-II,
BP 201T. HUMAN ANATOMY AND PHYSIOLOGY-II (Theory),
Nervous System:
Organization of nervous system, neuron, neuroglia, classification and properties of nerve fibre, electrophysiology, action potential, nerve impulse, receptors, synapse, neurotransmitters. Central nervous system: Meninges, ventricles of brain and
cerebrospinal fluid.structure and functions of brain (cerebrum, brain stem, cerebellum), spinal cord (gross structure, functions of afferent and efferent nerve tracts,reflex activity).
The nervous system of vertebrates (including humans) is divided into the central nervous system (CNS) and the peripheral nervous system (PNS). The (CNS) is the major division, and consists of the brain and the spinal cord. The spinal canal contains the spinal cord, while the cranial cavity contains the brain.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
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2. Overview
The nervous system is coordinates and
controls body function. It receives sensory
input, makes decisions, and then orders body
responses. The nervous system can be
subdivided into the central nervous system
(CNS) and the peripheral nervous system
(PNS).
3. The Central Nervous System
The CNS consists of the brain and the spinal cord; it is able to
receive impulses from all over the body, process this information,
and then respond with an action.
Sensory information comes into the central nervous system, where
it is processed. Motor messages then exit the CNS carrying
commands to the muscles and glands.
Consist of gray and white matter
gray matter: comprised of unsheathed or uncovered cell bodies
and dendrites
white matter: myelinated nerve fibers
Encased and protected by 3 membranes known as meninges
4. Brain
One of the largest organs in the body and
coordinates most body activities.
Center for all thought, memory, judgement,
and emotion
Each part of the brain is responsible for
controlling different body functions, such as
temperature regulation, blood pressure, and
breathing
5. Brain (cont.)
4 sections:
cerebrum: largest section that processes thoughts,
judgement, memory problem solving, and language
Subdivided into left and right cerebral hemispheres and
each hemisphere has 4 lobes-- frontal, parietal,
occipital, and temporal lobes
cerebellum: 2nd largest portion located beneath the
posterior part of the cerebrum; aids in coordinating
voluntary body movements and maintaining balance and
equilibrium.
6. Brain (cont.)
diencephalon: located below the cerebrum and consist if the
thalamus and hypothalamus
thalamus: composed of gray matter and acts as center for
relaying impulses from eyes, ears, and skin to the
cerebrum; pain receptors
hypothalamus: controls body temperature, appetite, sleep,
sexual desire, and emotions; also controlling the autonomic
nervous system, digestive system, release of hormones from
pituitary gland.
brain stem: 3 components
midbrain: pathway for impulses to be conducted between
brain and spinal cord
pons: connects cerebellum to the rest of the brain
medulla oblongata: most inferior positioned of the brain
connects brain to the spinal cord; center that controls
heart rate, respiration, and blood pressure
7. Spinal Cord
The function of the spinal cord is to provide
a pathway for impulses traveling to and from
the brain.
Column of nervous tissue that extends from
the medulla oblongata to the brain down the
2nd lumbar vertebra within the vertebral
column
33 vertebrae of the backbone form a
continuous canal for the spinal cord called
the spinal cavity or vertebral canal
8. Spinal Cord (cont.)
Protected by cerebrospinal fluid
Inner core of spinal cord consists of cell
bodies and dendrites of peripheral nerves
and is gray matter
Out portion of spinal cord is myelinated
white matter
ascending tracts: carrying sensory
information to brain
descending tracts: carrying motor
commands down from the brain to the
peripheral nerve
9. Peripheral Nervous Sytem
The PNS includes both 12 cranial nerves and 31 pairs of spinal
nerves
Cranial nerves arise from the brain, mainly the medulla
oblongata
Spinal nerves split off from the spinal cord, and 1 pair (right
and left) exit between each pair of vertebrae
The nerves of the PNS are subdivided into 2 divisions
autonomic nervous system (ANS): Involved with the control of
involuntary or unconscious bodily functions
2 branches- sympathetic and parasympathetic branches
somatic nerves: The skin and skeletal muscles are mainly
involved with the conscious and voluntary activities of the
body. These nerves carry motor commands to skeletal muscles