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C.N.SC.N.S.. Brain AnatomyBrain Anatomy
Dr.Mohamed Ashraf Zaitoun, MD
Interventional Radiology Consultant, Zagazig University
Hospitals, Egypt
FINR-Switzerland
zaitoun82@gmail.com
www.zaitounclinic.com
DedicationDedication
To the memory of my late father, Prof Ashraf ZaitounTo the memory of my late father, Prof Ashraf Zaitoun
Interventional
Radiology Unit,
Zagazig University,
Egypt
Embryology of the brainEmbryology of the brain
Prosencephalon ( forebrainProsencephalon ( forebrain((
Mesencephalon ( midbrainMesencephalon ( midbrain((
Rhombencephalon ( hindbrainRhombencephalon ( hindbrain((
Prosencephalon = ForebrainProsencephalon = Forebrain::
Telencephalon + DiencephalonTelencephalon + Diencephalon
**TelencephalonTelencephalon::
Cerebral cortex + Basal GangliaCerebral cortex + Basal Ganglia
**DiencephalonDiencephalon::
--The diencephalon is connected above and inThe diencephalon is connected above and in
front with the cerebral hemispheres; behind withfront with the cerebral hemispheres; behind with
the midbrain. Its upper surface is concealed bythe midbrain. Its upper surface is concealed by
the corpus callosum, and is covered by a fold ofthe corpus callosum, and is covered by a fold of
pia mater, named the tela chorioidea of the thirdpia mater, named the tela chorioidea of the third
ventricle; inferiorly it reaches to the base of theventricle; inferiorly it reaches to the base of the
brainbrain..
--It comprisesIt comprises::
11--thalamencephalothalamencephalo::
A)A) ThalamusThalamus
B)B) EpithalamusEpithalamus,, consisting of the trigonumconsisting of the trigonum
habenulae, the pineal body, and the posteriorhabenulae, the pineal body, and the posterior
commissurecommissure
2- Hypothalamus2- Hypothalamus
3- Post. Part of the 33- Post. Part of the 3rdrd
ventricleventricle
Mesencephalon = MidbrainMesencephalon = Midbrain
**Tectum + Tegmentum + Cerebral pedunclesTectum + Tegmentum + Cerebral peduncles
**Tectum ( dorsal part of midbrain) consists of sup. Colliculi ( visualTectum ( dorsal part of midbrain) consists of sup. Colliculi ( visual
receptors ) & inf. Colliculireceptors ) & inf. Colliculi
))auditory receptors ) + tectal plateauditory receptors ) + tectal plate
**Tegmentum ( region ventral to ventricular systemTegmentum ( region ventral to ventricular system((
**Caudally joins the pons , rostrally joins the diencephalonCaudally joins the pons , rostrally joins the diencephalon
**Located below the cerebral cortex & above the hindrain , placing itLocated below the cerebral cortex & above the hindrain , placing it
near the center of the brainnear the center of the brain
Rhomencephalon = HindbrainRhomencephalon = Hindbrain
**Medulla + Pons + CerebellumMedulla + Pons + Cerebellum
Anatomy of the brainAnatomy of the brain
Cerebral hemispheresCerebral hemispheres
Cerebral cortexCerebral cortex
White matter of the hemispheresWhite matter of the hemispheres
Basal gangliaBasal ganglia
Thalamus , hypothalamus & pineal glandThalamus , hypothalamus & pineal gland
Pituitary glandPituitary gland
Limbic lobeLimbic lobe
BrainstemBrainstem
CerebellumCerebellum
MeningesMeninges
Cerebral hemispheresCerebral hemispheres
--Fills the cranial cavity above the tentoriumFills the cranial cavity above the tentorium
cerebellicerebelli
--RT & LT hemispheres are connected byRT & LT hemispheres are connected by<<<<
Corpus callosum , separated by medianCorpus callosum , separated by median
longitudinal fissurelongitudinal fissure
Cerebral cortexCerebral cortex
--Lateral sulcus ( sylvian fissureLateral sulcus ( sylvian fissure( <<( <<
Separates frontal & temporal lobesSeparates frontal & temporal lobes
--Central sulcus ( of ronaldo ) : passes upwards from theCentral sulcus ( of ronaldo ) : passes upwards from the
lateral sulcus to the superior border of the hemispherelateral sulcus to the superior border of the hemisphere
>> Separates frontal & parietal lobes>> Separates frontal & parietal lobes
--Parieto-occipital sulcusParieto-occipital sulcus<<<<
Separates parietal & occipital lobesSeparates parietal & occipital lobes
****N.BN.B..
--Cingulate gyrusCingulate gyrus<<<<
Extends posteriorly from the frontal lobe into theExtends posteriorly from the frontal lobe into the
parietal lobeparietal lobe
--Insula ( of ReilInsula ( of Reil( <<( <<
Is the cortex burried in the floor of the lateralIs the cortex burried in the floor of the lateral
sulcus & is crossed by branches of MCAsulcus & is crossed by branches of MCA
The parts of the frontal , parietal & temporal lobesThe parts of the frontal , parietal & temporal lobes
that overlie the insula >> operculumthat overlie the insula >> operculum
Cingulate Gyrus
Genu of corpus
callosum
Ethmoid
air cells
Oral cavity
Splenium of
Corpus
callosum
Fourth Ventricle
White matter of the hemispheresWhite matter of the hemispheres
--33types of fiberstypes of fibers::
**Commisural fibers >> connect correspondingCommisural fibers >> connect corresponding
areas of the 2 hemispheresareas of the 2 hemispheres
**Association ( arcuate ) fibers >> connectAssociation ( arcuate ) fibers >> connect
different parts of the cortex of the samedifferent parts of the cortex of the same
hemispherehemisphere
**Projection fibers >> connect the cortex to lowerProjection fibers >> connect the cortex to lower
centerscenters
Commissural fibersCommissural fibers::
11--Corpus callosumCorpus callosum
Rostrum >> 1Rostrum >> 1stst
part which extends anteriorly frompart which extends anteriorly from
the ant. Commisurethe ant. Commisure
Genu >> most ant. PartGenu >> most ant. Part
Trunk ( body ) >> from genu ant. To spleniumTrunk ( body ) >> from genu ant. To splenium
postpost..
Splenium >> thickened post. partSplenium >> thickened post. part
****N.BN.B..
--Fibers from the genu that arch forward to theFibers from the genu that arch forward to the
frontal cortex on each side >> forceps minorfrontal cortex on each side >> forceps minor
--Fibers from the splenium passing post. To eachFibers from the splenium passing post. To each
occipital cortex >> forceps majoroccipital cortex >> forceps major
--Fibers extending laterally from the body of theFibers extending laterally from the body of the
CC >> tapetum ( form part of the roof & lateralCC >> tapetum ( form part of the roof & lateral
wall of the lateral ventriclewall of the lateral ventricle((
Projection fibersProjection fibers
--These fibers join the cerebral cortex to lowerThese fibers join the cerebral cortex to lower
centers >> internal capsulecenters >> internal capsule
--Ant. Limb between caudate & lentifomAnt. Limb between caudate & lentifom
--Post. Limb between thalamus & lentiformPost. Limb between thalamus & lentiform
--Both limbs meet at right angle >> genuBoth limbs meet at right angle >> genu
Basal gangliaBasal ganglia
--Corpus striatum ( caudate & lentiformCorpus striatum ( caudate & lentiform((
--Amygdaloid bodyAmygdaloid body
--ClaustrumClaustrum
**Caudate nucleusCaudate nucleus::
--Head , body & tail , its long & thin tail ends in the amygdaloidHead , body & tail , its long & thin tail ends in the amygdaloid
nucleusnucleus
--Lies in the concavity of the lateral VLies in the concavity of the lateral V
--Its head projects in the floor of the ant. Horn & its body lies alongIts head projects in the floor of the ant. Horn & its body lies along
the body of the lat. V , its tail lies in the roof of the inferior hornthe body of the lat. V , its tail lies in the roof of the inferior horn
of this Vof this V
**LentiformLentiform::
--Made up of a larger lateral putamen & a smallerMade up of a larger lateral putamen & a smaller
medial globus pallidusmedial globus pallidus
--Separated from head of caudate ant. & from theSeparated from head of caudate ant. & from the
thalamus post. By the internal capsulethalamus post. By the internal capsule
--A thin layer of white matter on its lateral surfaceA thin layer of white matter on its lateral surface
>> external capsule>> external capsule
**ClaustrumClaustrum::
--Thin sheet of grey matter lies between theThin sheet of grey matter lies between the
putamen & the insulaputamen & the insula
--It is separated medially from the putamen by theIt is separated medially from the putamen by the
external capsule & bounded laterally by a thinexternal capsule & bounded laterally by a thin
sheet of white mattersheet of white matter
))the extreme capsule ) just deep to the insulathe extreme capsule ) just deep to the insula
Thalamus , hypothalamus & pineal glandThalamus , hypothalamus & pineal gland
--The structures around the 3The structures around the 3rdrd
ventricle include : thalamus , hypothalamus &ventricle include : thalamus , hypothalamus &
pineal gland , together with the habenula these form the diencephalonpineal gland , together with the habenula these form the diencephalon
**ThalamusThalamus::
--RelationsRelations<<<<……
--The superior part of the thalamus forms part of the floor of the lateral VThe superior part of the thalamus forms part of the floor of the lateral V
--The thalamus is attached in 60 % of cases to the thalamus of the other side byThe thalamus is attached in 60 % of cases to the thalamus of the other side by
the interthalamic adhesions or massa intermediathe interthalamic adhesions or massa intermedia
--Medial & lateral swellings on the postero-inferior aspect of the thalamus areMedial & lateral swellings on the postero-inferior aspect of the thalamus are
called the geniculate bodies , the medial geniculate body is attached to the inf.called the geniculate bodies , the medial geniculate body is attached to the inf.
Colliculus & the lateral geniculate body is attached to sup. ColliculusColliculus & the lateral geniculate body is attached to sup. Colliculus
--Blood supply >> thalamo-striate branches of PCABlood supply >> thalamo-striate branches of PCA
**HypothalamusHypothalamus::
--Forms the floor of the 3Forms the floor of the 3rdrd
VV
--It includesIt includes::
****Optic chiasmOptic chiasm
****Tuber cinereum >> a sheet of gray matter between the optic chiasm & theTuber cinereum >> a sheet of gray matter between the optic chiasm & the
mamillary bodiesmamillary bodies
****Infundibular stalk >> leading down to the post. Lobe of the pituitary glandInfundibular stalk >> leading down to the post. Lobe of the pituitary gland
****Mamillary bodies >> round masses in which the columns of the fornix ( vidaMamillary bodies >> round masses in which the columns of the fornix ( vida
infra ) endinfra ) end
****Post. Perforated substancePost. Perforated substance
--Blood supply >> branches of ACA , PCA & post. Communicating arteries ,Blood supply >> branches of ACA , PCA & post. Communicating arteries ,
drained by thalamo-striate veinsdrained by thalamo-striate veins
**Pineal glandPineal gland::
--Lies between the post. Ends of the thalami & betweenLies between the post. Ends of the thalami & between
the splenium above & the sup. Colliculi belowthe splenium above & the sup. Colliculi below
--It is separated from the splenium by the cerebral veins , itIt is separated from the splenium by the cerebral veins , it
lies within 3 mm of the midlinelies within 3 mm of the midline
--The pineal stalk has superior & inferior laminae , the sup.The pineal stalk has superior & inferior laminae , the sup.
Is formed by the habenular commisure & the inf.Is formed by the habenular commisure & the inf.
Contains the post. Commisure , between these lamina isContains the post. Commisure , between these lamina is
the post. Recess of the 3the post. Recess of the 3rdrd
ventricleventricle
A. Genu of the Corpus Callosum
B. Anterior Horn of the Lateral
Ventricle
C. Internal Capsule
D. Thalamus
E. Pineal Gland
F. Choroid Plexus
G. Straight Sinus
Pituitary gland ( hypophysis cerebriPituitary gland ( hypophysis cerebri((
--Site >> pituitary ( hypophyseal ) fossaSite >> pituitary ( hypophyseal ) fossa
--Measuring >> 12 mm in transverse diamMeasuring >> 12 mm in transverse diam..
88mm in AP diametermm in AP diameter
99mm in heightmm in height
--Formed ofFormed of::
**Infundibulum ( stalk ) >> the connection between the hypothalamus & post.Infundibulum ( stalk ) >> the connection between the hypothalamus & post.
pituitarypituitary
**Ant. LobeAnt. Lobe<<<<
--55times larger than the post. Lobetimes larger than the post. Lobe
--Developed from the rathkeDeveloped from the rathke’’s pouch in the roof of the primitve mouths pouch in the roof of the primitve mouth
--Craniopharyngioma is a tumor from the remnant of its epitheliumCraniopharyngioma is a tumor from the remnant of its epithelium
--Ant. Lobe is adherent to the post. Lobe by narrow zone called Pars intermedia ,Ant. Lobe is adherent to the post. Lobe by narrow zone called Pars intermedia ,
actually it is a part of the anterior lobeactually it is a part of the anterior lobe
**Post. LobePost. Lobe<<<<
--Much smaller than the ant. LobeMuch smaller than the ant. Lobe
--Developed from the nerve fibers whose cell bodies lie in the hypothalamusDeveloped from the nerve fibers whose cell bodies lie in the hypothalamus
--RelationsRelations::
**Above >> Diaphragma sella ( dura matterAbove >> Diaphragma sella ( dura matter((
&&above this the suprasellar cistern with optic chiasm anteriorly &above this the suprasellar cistern with optic chiasm anteriorly &
circle of williscircle of willis
**Below >> the body of sphenoid & sphenoid sinusBelow >> the body of sphenoid & sphenoid sinus
**Laterally >> Dura matterLaterally >> Dura matter
Cavernous sinus & its contentCavernous sinus & its content::
ICA ,, 3ICA ,, 3rdrd
, 4, 4thth
cranial nerves , ophthalmic division of 5cranial nerves , ophthalmic division of 5thth
cranialcranial
nerve & 6nerve & 6thth
cranial nervecranial nerve
----N.B. >> The cavernous sinuses are united by the intercavernousN.B. >> The cavernous sinuses are united by the intercavernous
sinuses which surround the pituitary gland ant. , post. & infsinuses which surround the pituitary gland ant. , post. & inf..
--Sella turicicaSella turicica::
**It is a superior saddle shaped formation on the intracranial aspect of the body ofIt is a superior saddle shaped formation on the intracranial aspect of the body of
sphenoid bone containing pituitary glandsphenoid bone containing pituitary gland
**Boundaries : ant. >> ant. Clinoid processBoundaries : ant. >> ant. Clinoid process
post. >> post. Clinoid processpost. >> post. Clinoid process
lat. >> cavernous sinuslat. >> cavernous sinus
**AnatomyAnatomy::
The seat of the saddle is known as the hypophyseal fossa, which holds theThe seat of the saddle is known as the hypophyseal fossa, which holds the
pituitary gland. The hypophyseal fossa is located in a depression in the bodypituitary gland. The hypophyseal fossa is located in a depression in the body
of the sphenoid bone. Located anteriorly to the hypophyseal fossa is theof the sphenoid bone. Located anteriorly to the hypophyseal fossa is the
tuberculum sellae ( optic foramen lies on either sides of ittuberculum sellae ( optic foramen lies on either sides of it((
Completing the formation of the saddle posteriorly is the dorsum sellae which isCompleting the formation of the saddle posteriorly is the dorsum sellae which is
continuous with the clivus, inferoposteriorly. The dorsum sellae is terminatedcontinuous with the clivus, inferoposteriorly. The dorsum sellae is terminated
laterally by the posterior clinoid processlaterally by the posterior clinoid process..
--Arterial supplyArterial supply::
ICAICA
**Sup. Hypophyseal arteriesSup. Hypophyseal arteries
**Inf. Hypophyseal arteriesInf. Hypophyseal arteries
--Venous drainageVenous drainage::
To cavernous & inter-cavernosal sinusesTo cavernous & inter-cavernosal sinuses
--Radiological featuresRadiological features::
11--Skull radiographySkull radiography<<<<
Lateral viewLateral view
22--CT & MRICT & MRI<<<<
**Best on sagittal & coronalBest on sagittal & coronal
**Post. Pituitary appears high signal intensity on unenhanced T1 WIsPost. Pituitary appears high signal intensity on unenhanced T1 WIs
**Dura above the sella must be horizontal not convexDura above the sella must be horizontal not convex
--Infundibulum diameter should be not bigger than the adjacent basilar arteryInfundibulum diameter should be not bigger than the adjacent basilar artery
**Sella itself is delineated bySella itself is delineated by::
Signal void of the bony cortexSignal void of the bony cortex
High intensity signal of marrow in the clivusHigh intensity signal of marrow in the clivus
**Optic nerves,chiasm & ICA vessels above & sphenoid sinus below seen clearlyOptic nerves,chiasm & ICA vessels above & sphenoid sinus below seen clearly
on coronal sectionson coronal sections
Limbic lobeLimbic lobe
--This is not an anatomical lobe as such but functionally relatedThis is not an anatomical lobe as such but functionally related
structures that surrounds the corpus callosum on the medialstructures that surrounds the corpus callosum on the medial
surface of the cerebral hemispheresurface of the cerebral hemisphere
--It includesIt includes::
Cingulate gyrusCingulate gyrus
Splenial gyrusSplenial gyrus
Parahippocampal gyrusParahippocampal gyrus
HippocampusHippocampus
Dentate gyrusDentate gyrus
fornixfornix
--The cingulate gyrus curves around the genu & body ofThe cingulate gyrus curves around the genu & body of
CC and continues around the splenium as splenial gyrusCC and continues around the splenium as splenial gyrus
>> this in turn is continuous with dentate gyrus &>> this in turn is continuous with dentate gyrus &
hippocampushippocampus
--Hippocampus >> is a curved elevation in the floor of theHippocampus >> is a curved elevation in the floor of the
inf. Horn of the lateral ventricleinf. Horn of the lateral ventricle
--Fornix >> is an efferent pathway from the hippocampusFornix >> is an efferent pathway from the hippocampus
to the mamillary bodiesto the mamillary bodies
BrainstemBrainstem
--Connects the cerebral hemispheres to the spinalConnects the cerebral hemispheres to the spinal
cord , extends from just above the tentorialcord , extends from just above the tentorial
hiatus to just below the foramen magnumhiatus to just below the foramen magnum
--It is bounded ant. By the clivus-basisphenoidIt is bounded ant. By the clivus-basisphenoid
above & the basiocciput belowabove & the basiocciput below
--has three parts : midbrain , pons & medullahas three parts : midbrain , pons & medulla
**MidbrainMidbrain::
--Anteriorly two cerebral peduncles are seen separated theAnteriorly two cerebral peduncles are seen separated the
interpeduncular fossainterpeduncular fossa
--The post. Surface of the midbrain presents four roundedThe post. Surface of the midbrain presents four rounded
prominences ( the corpora quadrigemina or the sup. &prominences ( the corpora quadrigemina or the sup. &
inf. Colliculiinf. Colliculi( ,( ,
each sup. Colliculus >> lateral geniculate body of theeach sup. Colliculus >> lateral geniculate body of the
optic tractoptic tract
Each inf. Colliculus >> medial geniculate body of theEach inf. Colliculus >> medial geniculate body of the
auditory systemauditory system
--Cerebral peduncles have a ventral part , the crusCerebral peduncles have a ventral part , the crus
cerebri and a dorsal part , the tegmentum , thesecerebri and a dorsal part , the tegmentum , these
are separated by the substantia nigraare separated by the substantia nigra
--The part of the midbrain posterior to theThe part of the midbrain posterior to the
aqueduct is called the tectum or quadrigeminalaqueduct is called the tectum or quadrigeminal
plateplate
--Cranial nerves >> 3Cranial nerves >> 3rdrd
& 4& 4thth
cranial nervescranial nerves
--Blood supply >> Sup. cerebellarBlood supply >> Sup. cerebellar
**PonsPons::
--A shallow groove is seen in the midline , the basilar arteryA shallow groove is seen in the midline , the basilar artery
may lie in this groove , but often lies lateral to itmay lie in this groove , but often lies lateral to it
--The post. Surface of the pons forms the upper part ofThe post. Surface of the pons forms the upper part of
the floor of the 4the floor of the 4thth
ventricleventricle
--Cranial nerves >> 5Cranial nerves >> 5thth
& 6& 6thth
cranial nervescranial nerves
77thth
& 8& 8thth
cranial nerves emerges at the junction with thecranial nerves emerges at the junction with the
medulla laterally >> CPA ( cerebello-pontine anglemedulla laterally >> CPA ( cerebello-pontine angle((
--Blood supply >> pontine branches of the basilar ABlood supply >> pontine branches of the basilar A
**Medulla oblongataMedulla oblongata::
--Ant. The ventral median fissure is deep in its superior part , a ridgeAnt. The ventral median fissure is deep in its superior part , a ridge
on each side of this fissure is formed by the pyramidal fibers andon each side of this fissure is formed by the pyramidal fibers and
is called the pyramid , lateral to the pyramid in the upper medullais called the pyramid , lateral to the pyramid in the upper medulla
is an oval bulge called the olive , lateral to the olive lies the inf.is an oval bulge called the olive , lateral to the olive lies the inf.
Cerebellar peduncle joining the medulla to the cerebellumCerebellar peduncle joining the medulla to the cerebellum
--Post. The upper part of the medulla is open in the floor of the 4Post. The upper part of the medulla is open in the floor of the 4thth
ventricleventricle
--Cranial nerves >> 9Cranial nerves >> 9thth
, 10, 10thth
, 11, 11thth
& 12& 12thth
cranial nervescranial nerves
--blood supply >> ant. Part : vertebral & basilarblood supply >> ant. Part : vertebral & basilar
post. Part : PICApost. Part : PICA
CerebellumCerebellum
--The cerebellum lies in the post. Fossa , it is separated from theThe cerebellum lies in the post. Fossa , it is separated from the
occipital lobe by the tentorium & from the the pons andoccipital lobe by the tentorium & from the the pons and
midbrain by the 4midbrain by the 4thth
VV
--It is connected to the brainstem by 3 pairs of cerebellar pedunclesIt is connected to the brainstem by 3 pairs of cerebellar peduncles::
Sup. Cerebellar peduncles to the midbrainSup. Cerebellar peduncles to the midbrain
Middle Cerebellar peduncles to the ponsMiddle Cerebellar peduncles to the pons
Inf. Cerebellar peduncles to the medullaInf. Cerebellar peduncles to the medulla
--There are 2 hemispheres with the midline vermis betweenThere are 2 hemispheres with the midline vermis between
--The hemispheres >> on each side below the middle cerebellarThe hemispheres >> on each side below the middle cerebellar
peduncle is the folliculus , the tonsils are the most ant. Inf. Partpeduncle is the folliculus , the tonsils are the most ant. Inf. Part
of the hemispheres and lie close to the midlineof the hemispheres and lie close to the midline
--The vermis >> is the narrow midline portion of the cerebllum ,The vermis >> is the narrow midline portion of the cerebllum ,
sup. There is a low median elevation not clearly separated fromsup. There is a low median elevation not clearly separated from
the hemispheres , however inf. The vermis is quite separate &the hemispheres , however inf. The vermis is quite separate &
lies in a deep cleft called the vallecula , the most ant. Part of thelies in a deep cleft called the vallecula , the most ant. Part of the
sup. Vermis is the lingula , which lies on the sup. Medullarysup. Vermis is the lingula , which lies on the sup. Medullary
vilumvilum
))a thin sheet of white matter between the sup. Cerebellar pedunclesa thin sheet of white matter between the sup. Cerebellar peduncles
) , the most ant. Part of the inf. Vermis is the nodule) , the most ant. Part of the inf. Vermis is the nodule
--SubdivisionsSubdivisions::
Ant. LobeAnt. Lobe
Post. LobePost. Lobe
Flocculonodular lobeFlocculonodular lobe
--Arterial supplyArterial supply::
PICA from the vertebralPICA from the vertebral
AICA from the basilarAICA from the basilar
Sup. Cerebellar arteries from basilar ASup. Cerebellar arteries from basilar A
--Venous drainageVenous drainage::
Precentral cerebellar vein & the sup. Vermian vein drain to the great cerebral veinPrecentral cerebellar vein & the sup. Vermian vein drain to the great cerebral vein
Remaining of the cerebellar vein >> nearby dural sinusesRemaining of the cerebellar vein >> nearby dural sinuses
))straight , transverse , inf. Petrosal , sigmoid & occipital sinusesstraight , transverse , inf. Petrosal , sigmoid & occipital sinuses((
N.B. >> the normal floculus enhances more than the rest of the cerebellum , shouldnotN.B. >> the normal floculus enhances more than the rest of the cerebellum , shouldnot
be mistaken for a more ant. Located acoustic neuromabe mistaken for a more ant. Located acoustic neuroma
A. Frontal Lobe
B. Frontal Bone )Superior
Surface of Orbital Part(
C. Dorsum Sellae
D. Basilar Artery
E. Temporal Lobe
F. Mastoid Air Cells
G. Cerebellar Hemisphere
A. Falx Cerebri
B. Frontal Lobe
C. Anterior Horn of
Lateral Ventricle
D. Third Ventricle
E. Quadrigeminal
Plate Cistern
F. Cerebellum
MeningesMeninges
--Three layers of meninges cover the brain & spinal cord >> dura ,Three layers of meninges cover the brain & spinal cord >> dura ,
arachnoid & piaarachnoid & pia
**Dura materDura mater::
--Two layers , outer layer which is the periosteum of the inner aspectTwo layers , outer layer which is the periosteum of the inner aspect
of the skull , the inner layer is the dura mater properof the skull , the inner layer is the dura mater proper
--Falx cerebri >> sickle-shaped dural septum in the median sagittalFalx cerebri >> sickle-shaped dural septum in the median sagittal
plane attached to the crista galli in the midline of the floor of theplane attached to the crista galli in the midline of the floor of the
ant. Cranial fossa & along the midline of the inner aspect of theant. Cranial fossa & along the midline of the inner aspect of the
vault of the skull to the margins of the SSSvault of the skull to the margins of the SSS
--Diaphragma sellae >> is a horizontal fold of dura thatDiaphragma sellae >> is a horizontal fold of dura that
almost completely covers the pituitary fossa , with aalmost completely covers the pituitary fossa , with a
small opening for the pituitary stalksmall opening for the pituitary stalk
--Tentorium cerebelli >> is a horizontal septum of duraTentorium cerebelli >> is a horizontal septum of dura
mater that separates the occipital lobes from themater that separates the occipital lobes from the
superior surface of the cerebellumsuperior surface of the cerebellum
--Falx cerebelli >> is a low elevation of dura that projectsFalx cerebelli >> is a low elevation of dura that projects
a small distance into the cerebellar interhemispherica small distance into the cerebellar interhemispheric
fissurefissure
**Arachnoid materArachnoid mater::
--Delicate membrane which is impermeable to CSF , itDelicate membrane which is impermeable to CSF , it
lines the dura matter separated from it only by a thinlines the dura matter separated from it only by a thin
layer of lymph in the subdural ( potential spacelayer of lymph in the subdural ( potential space((
--It is separated from the pia mater by the subarachnoidIt is separated from the pia mater by the subarachnoid
space , which contains the CSFspace , which contains the CSF
--Arachnoid mater herniates through holes in the dura intoArachnoid mater herniates through holes in the dura into
the venous sinuses & venous lakes as arachnoid villi >>the venous sinuses & venous lakes as arachnoid villi >>
CSF absorptionCSF absorption
**Pia materPia mater::
--Closely adherent to the brain surfaceClosely adherent to the brain surface
--It invaginates with with the choroid vessels intoIt invaginates with with the choroid vessels into
the ventricles , & the layer of pia mater &the ventricles , & the layer of pia mater &
ependyma together thus formed over theseependyma together thus formed over these
vessels is called >> tela choroidea of thevessels is called >> tela choroidea of the
ventriclesventricles
--Arterial supply of the meningesArterial supply of the meninges::
**MMA ( middle meningeal arteryMMA ( middle meningeal artery((
branch of the maxillary artery that enters the the cranium through foramenbranch of the maxillary artery that enters the the cranium through foramen
spinosum , it passes laterally in the floor of the middle cranial fossa , thenspinosum , it passes laterally in the floor of the middle cranial fossa , then
superiorly & anteriorly along the greater wing of sphenoid , where it dividessuperiorly & anteriorly along the greater wing of sphenoid , where it divides
into ant. & post. Branchesinto ant. & post. Branches
**Additional supplyAdditional supply<<<<
--Ant. Cranial fossa : meningeal branches of ophthalmic & ant. & post. EthmoidAnt. Cranial fossa : meningeal branches of ophthalmic & ant. & post. Ethmoid
arteriesarteries
--Cavernous sinus : meningeal branches of carotid artery & the accessoryCavernous sinus : meningeal branches of carotid artery & the accessory
meningeal arterymeningeal artery
--Post. Fossa : meningeal branches of vertebral arteryPost. Fossa : meningeal branches of vertebral artery
--Nerve supply : 5Nerve supply : 5thth
, 9, 9thth
& 10& 10thth
cranial nerves , with the dura around the foramencranial nerves , with the dura around the foramen
magnum being innervated by C1-3 nervesmagnum being innervated by C1-3 nerves
--Radiological featuresRadiological features::
**Extradural hematomaExtradural hematoma
--Occurs when a vessel in the extradural space between dura and bone is torn byOccurs when a vessel in the extradural space between dura and bone is torn by
trauma >> MMAtrauma >> MMA
**Subdural hematomaSubdural hematoma
--Also due to traumatic bleed in space between dura & arachnoid >> bridgingAlso due to traumatic bleed in space between dura & arachnoid >> bridging
veinsveins
--Subdural hematoma can extend into interhemispheric fissure & root of sylvianSubdural hematoma can extend into interhemispheric fissure & root of sylvian
fissure on the brain surfacefissure on the brain surface
**Subarachnoid hemorrhageSubarachnoid hemorrhage
--In the subarachnoid space between the arachnoid & pia mater fromIn the subarachnoid space between the arachnoid & pia mater from
spontaneous or traumatic rupture of an arteryspontaneous or traumatic rupture of an artery
--Subarachnoid blood can then be seen in the cisterns & extending into sulci &Subarachnoid blood can then be seen in the cisterns & extending into sulci &
fissures on the brain surface close to the site of bleedingfissures on the brain surface close to the site of bleeding
**Skull radiographSkull radiograph::
--Dural calcification is common in older subjectsDural calcification is common in older subjects
--Calcification of falx cerebri or of the tentorium can be seen in OF or FO viewsCalcification of falx cerebri or of the tentorium can be seen in OF or FO views
**CT & MRICT & MRI::
--Above the level of the petrous temporal bone the cerebral hemispheres areAbove the level of the petrous temporal bone the cerebral hemispheres are
separated from the cerebellum by the tentoriumseparated from the cerebellum by the tentorium
--Best seen on contrast enhanced scans as it contains blood vesselsBest seen on contrast enhanced scans as it contains blood vessels
--The tentorium is seen as high attenuation linear structure extending laterallyThe tentorium is seen as high attenuation linear structure extending laterally
from the midbrain to the inner table of the skullfrom the midbrain to the inner table of the skull
--The falx ccerebri is seen on higher cuts ant. & post. Extending into theThe falx ccerebri is seen on higher cuts ant. & post. Extending into the
interhemispheric fissure almost to the corpus callosuminterhemispheric fissure almost to the corpus callosum
Radiological anatomy of the brain

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Radiological anatomy of the brain

  • 2. Dr.Mohamed Ashraf Zaitoun, MD Interventional Radiology Consultant, Zagazig University Hospitals, Egypt FINR-Switzerland zaitoun82@gmail.com www.zaitounclinic.com
  • 3. DedicationDedication To the memory of my late father, Prof Ashraf ZaitounTo the memory of my late father, Prof Ashraf Zaitoun Interventional Radiology Unit, Zagazig University, Egypt
  • 4. Embryology of the brainEmbryology of the brain Prosencephalon ( forebrainProsencephalon ( forebrain(( Mesencephalon ( midbrainMesencephalon ( midbrain(( Rhombencephalon ( hindbrainRhombencephalon ( hindbrain((
  • 5.
  • 6. Prosencephalon = ForebrainProsencephalon = Forebrain:: Telencephalon + DiencephalonTelencephalon + Diencephalon **TelencephalonTelencephalon:: Cerebral cortex + Basal GangliaCerebral cortex + Basal Ganglia
  • 7. **DiencephalonDiencephalon:: --The diencephalon is connected above and inThe diencephalon is connected above and in front with the cerebral hemispheres; behind withfront with the cerebral hemispheres; behind with the midbrain. Its upper surface is concealed bythe midbrain. Its upper surface is concealed by the corpus callosum, and is covered by a fold ofthe corpus callosum, and is covered by a fold of pia mater, named the tela chorioidea of the thirdpia mater, named the tela chorioidea of the third ventricle; inferiorly it reaches to the base of theventricle; inferiorly it reaches to the base of the brainbrain..
  • 8. --It comprisesIt comprises:: 11--thalamencephalothalamencephalo:: A)A) ThalamusThalamus B)B) EpithalamusEpithalamus,, consisting of the trigonumconsisting of the trigonum habenulae, the pineal body, and the posteriorhabenulae, the pineal body, and the posterior commissurecommissure 2- Hypothalamus2- Hypothalamus 3- Post. Part of the 33- Post. Part of the 3rdrd ventricleventricle
  • 9.
  • 10.
  • 11. Mesencephalon = MidbrainMesencephalon = Midbrain **Tectum + Tegmentum + Cerebral pedunclesTectum + Tegmentum + Cerebral peduncles **Tectum ( dorsal part of midbrain) consists of sup. Colliculi ( visualTectum ( dorsal part of midbrain) consists of sup. Colliculi ( visual receptors ) & inf. Colliculireceptors ) & inf. Colliculi ))auditory receptors ) + tectal plateauditory receptors ) + tectal plate **Tegmentum ( region ventral to ventricular systemTegmentum ( region ventral to ventricular system(( **Caudally joins the pons , rostrally joins the diencephalonCaudally joins the pons , rostrally joins the diencephalon **Located below the cerebral cortex & above the hindrain , placing itLocated below the cerebral cortex & above the hindrain , placing it near the center of the brainnear the center of the brain
  • 12. Rhomencephalon = HindbrainRhomencephalon = Hindbrain **Medulla + Pons + CerebellumMedulla + Pons + Cerebellum
  • 13. Anatomy of the brainAnatomy of the brain Cerebral hemispheresCerebral hemispheres Cerebral cortexCerebral cortex White matter of the hemispheresWhite matter of the hemispheres Basal gangliaBasal ganglia Thalamus , hypothalamus & pineal glandThalamus , hypothalamus & pineal gland Pituitary glandPituitary gland Limbic lobeLimbic lobe BrainstemBrainstem CerebellumCerebellum MeningesMeninges
  • 14. Cerebral hemispheresCerebral hemispheres --Fills the cranial cavity above the tentoriumFills the cranial cavity above the tentorium cerebellicerebelli --RT & LT hemispheres are connected byRT & LT hemispheres are connected by<<<< Corpus callosum , separated by medianCorpus callosum , separated by median longitudinal fissurelongitudinal fissure
  • 15. Cerebral cortexCerebral cortex --Lateral sulcus ( sylvian fissureLateral sulcus ( sylvian fissure( <<( << Separates frontal & temporal lobesSeparates frontal & temporal lobes --Central sulcus ( of ronaldo ) : passes upwards from theCentral sulcus ( of ronaldo ) : passes upwards from the lateral sulcus to the superior border of the hemispherelateral sulcus to the superior border of the hemisphere >> Separates frontal & parietal lobes>> Separates frontal & parietal lobes --Parieto-occipital sulcusParieto-occipital sulcus<<<< Separates parietal & occipital lobesSeparates parietal & occipital lobes
  • 16.
  • 17.
  • 18.
  • 19. ****N.BN.B.. --Cingulate gyrusCingulate gyrus<<<< Extends posteriorly from the frontal lobe into theExtends posteriorly from the frontal lobe into the parietal lobeparietal lobe --Insula ( of ReilInsula ( of Reil( <<( << Is the cortex burried in the floor of the lateralIs the cortex burried in the floor of the lateral sulcus & is crossed by branches of MCAsulcus & is crossed by branches of MCA The parts of the frontal , parietal & temporal lobesThe parts of the frontal , parietal & temporal lobes that overlie the insula >> operculumthat overlie the insula >> operculum
  • 20. Cingulate Gyrus Genu of corpus callosum Ethmoid air cells Oral cavity Splenium of Corpus callosum Fourth Ventricle
  • 21.
  • 22. White matter of the hemispheresWhite matter of the hemispheres --33types of fiberstypes of fibers:: **Commisural fibers >> connect correspondingCommisural fibers >> connect corresponding areas of the 2 hemispheresareas of the 2 hemispheres **Association ( arcuate ) fibers >> connectAssociation ( arcuate ) fibers >> connect different parts of the cortex of the samedifferent parts of the cortex of the same hemispherehemisphere **Projection fibers >> connect the cortex to lowerProjection fibers >> connect the cortex to lower centerscenters
  • 23. Commissural fibersCommissural fibers:: 11--Corpus callosumCorpus callosum Rostrum >> 1Rostrum >> 1stst part which extends anteriorly frompart which extends anteriorly from the ant. Commisurethe ant. Commisure Genu >> most ant. PartGenu >> most ant. Part Trunk ( body ) >> from genu ant. To spleniumTrunk ( body ) >> from genu ant. To splenium postpost.. Splenium >> thickened post. partSplenium >> thickened post. part
  • 24. ****N.BN.B.. --Fibers from the genu that arch forward to theFibers from the genu that arch forward to the frontal cortex on each side >> forceps minorfrontal cortex on each side >> forceps minor --Fibers from the splenium passing post. To eachFibers from the splenium passing post. To each occipital cortex >> forceps majoroccipital cortex >> forceps major --Fibers extending laterally from the body of theFibers extending laterally from the body of the CC >> tapetum ( form part of the roof & lateralCC >> tapetum ( form part of the roof & lateral wall of the lateral ventriclewall of the lateral ventricle((
  • 25.
  • 26.
  • 27.
  • 28.
  • 29.
  • 30.
  • 31.
  • 32.
  • 33.
  • 34.
  • 35. Projection fibersProjection fibers --These fibers join the cerebral cortex to lowerThese fibers join the cerebral cortex to lower centers >> internal capsulecenters >> internal capsule --Ant. Limb between caudate & lentifomAnt. Limb between caudate & lentifom --Post. Limb between thalamus & lentiformPost. Limb between thalamus & lentiform --Both limbs meet at right angle >> genuBoth limbs meet at right angle >> genu
  • 36.
  • 37. Basal gangliaBasal ganglia --Corpus striatum ( caudate & lentiformCorpus striatum ( caudate & lentiform(( --Amygdaloid bodyAmygdaloid body --ClaustrumClaustrum **Caudate nucleusCaudate nucleus:: --Head , body & tail , its long & thin tail ends in the amygdaloidHead , body & tail , its long & thin tail ends in the amygdaloid nucleusnucleus --Lies in the concavity of the lateral VLies in the concavity of the lateral V --Its head projects in the floor of the ant. Horn & its body lies alongIts head projects in the floor of the ant. Horn & its body lies along the body of the lat. V , its tail lies in the roof of the inferior hornthe body of the lat. V , its tail lies in the roof of the inferior horn of this Vof this V
  • 38. **LentiformLentiform:: --Made up of a larger lateral putamen & a smallerMade up of a larger lateral putamen & a smaller medial globus pallidusmedial globus pallidus --Separated from head of caudate ant. & from theSeparated from head of caudate ant. & from the thalamus post. By the internal capsulethalamus post. By the internal capsule --A thin layer of white matter on its lateral surfaceA thin layer of white matter on its lateral surface >> external capsule>> external capsule
  • 39. **ClaustrumClaustrum:: --Thin sheet of grey matter lies between theThin sheet of grey matter lies between the putamen & the insulaputamen & the insula --It is separated medially from the putamen by theIt is separated medially from the putamen by the external capsule & bounded laterally by a thinexternal capsule & bounded laterally by a thin sheet of white mattersheet of white matter ))the extreme capsule ) just deep to the insulathe extreme capsule ) just deep to the insula
  • 40.
  • 41. Thalamus , hypothalamus & pineal glandThalamus , hypothalamus & pineal gland --The structures around the 3The structures around the 3rdrd ventricle include : thalamus , hypothalamus &ventricle include : thalamus , hypothalamus & pineal gland , together with the habenula these form the diencephalonpineal gland , together with the habenula these form the diencephalon **ThalamusThalamus:: --RelationsRelations<<<<…… --The superior part of the thalamus forms part of the floor of the lateral VThe superior part of the thalamus forms part of the floor of the lateral V --The thalamus is attached in 60 % of cases to the thalamus of the other side byThe thalamus is attached in 60 % of cases to the thalamus of the other side by the interthalamic adhesions or massa intermediathe interthalamic adhesions or massa intermedia --Medial & lateral swellings on the postero-inferior aspect of the thalamus areMedial & lateral swellings on the postero-inferior aspect of the thalamus are called the geniculate bodies , the medial geniculate body is attached to the inf.called the geniculate bodies , the medial geniculate body is attached to the inf. Colliculus & the lateral geniculate body is attached to sup. ColliculusColliculus & the lateral geniculate body is attached to sup. Colliculus --Blood supply >> thalamo-striate branches of PCABlood supply >> thalamo-striate branches of PCA
  • 42.
  • 43. **HypothalamusHypothalamus:: --Forms the floor of the 3Forms the floor of the 3rdrd VV --It includesIt includes:: ****Optic chiasmOptic chiasm ****Tuber cinereum >> a sheet of gray matter between the optic chiasm & theTuber cinereum >> a sheet of gray matter between the optic chiasm & the mamillary bodiesmamillary bodies ****Infundibular stalk >> leading down to the post. Lobe of the pituitary glandInfundibular stalk >> leading down to the post. Lobe of the pituitary gland ****Mamillary bodies >> round masses in which the columns of the fornix ( vidaMamillary bodies >> round masses in which the columns of the fornix ( vida infra ) endinfra ) end ****Post. Perforated substancePost. Perforated substance --Blood supply >> branches of ACA , PCA & post. Communicating arteries ,Blood supply >> branches of ACA , PCA & post. Communicating arteries , drained by thalamo-striate veinsdrained by thalamo-striate veins
  • 44.
  • 45.
  • 46.
  • 47. **Pineal glandPineal gland:: --Lies between the post. Ends of the thalami & betweenLies between the post. Ends of the thalami & between the splenium above & the sup. Colliculi belowthe splenium above & the sup. Colliculi below --It is separated from the splenium by the cerebral veins , itIt is separated from the splenium by the cerebral veins , it lies within 3 mm of the midlinelies within 3 mm of the midline --The pineal stalk has superior & inferior laminae , the sup.The pineal stalk has superior & inferior laminae , the sup. Is formed by the habenular commisure & the inf.Is formed by the habenular commisure & the inf. Contains the post. Commisure , between these lamina isContains the post. Commisure , between these lamina is the post. Recess of the 3the post. Recess of the 3rdrd ventricleventricle
  • 48.
  • 49. A. Genu of the Corpus Callosum B. Anterior Horn of the Lateral Ventricle C. Internal Capsule D. Thalamus E. Pineal Gland F. Choroid Plexus G. Straight Sinus
  • 50. Pituitary gland ( hypophysis cerebriPituitary gland ( hypophysis cerebri(( --Site >> pituitary ( hypophyseal ) fossaSite >> pituitary ( hypophyseal ) fossa --Measuring >> 12 mm in transverse diamMeasuring >> 12 mm in transverse diam.. 88mm in AP diametermm in AP diameter 99mm in heightmm in height
  • 51. --Formed ofFormed of:: **Infundibulum ( stalk ) >> the connection between the hypothalamus & post.Infundibulum ( stalk ) >> the connection between the hypothalamus & post. pituitarypituitary **Ant. LobeAnt. Lobe<<<< --55times larger than the post. Lobetimes larger than the post. Lobe --Developed from the rathkeDeveloped from the rathke’’s pouch in the roof of the primitve mouths pouch in the roof of the primitve mouth --Craniopharyngioma is a tumor from the remnant of its epitheliumCraniopharyngioma is a tumor from the remnant of its epithelium --Ant. Lobe is adherent to the post. Lobe by narrow zone called Pars intermedia ,Ant. Lobe is adherent to the post. Lobe by narrow zone called Pars intermedia , actually it is a part of the anterior lobeactually it is a part of the anterior lobe **Post. LobePost. Lobe<<<< --Much smaller than the ant. LobeMuch smaller than the ant. Lobe --Developed from the nerve fibers whose cell bodies lie in the hypothalamusDeveloped from the nerve fibers whose cell bodies lie in the hypothalamus
  • 52. --RelationsRelations:: **Above >> Diaphragma sella ( dura matterAbove >> Diaphragma sella ( dura matter(( &&above this the suprasellar cistern with optic chiasm anteriorly &above this the suprasellar cistern with optic chiasm anteriorly & circle of williscircle of willis **Below >> the body of sphenoid & sphenoid sinusBelow >> the body of sphenoid & sphenoid sinus **Laterally >> Dura matterLaterally >> Dura matter Cavernous sinus & its contentCavernous sinus & its content:: ICA ,, 3ICA ,, 3rdrd , 4, 4thth cranial nerves , ophthalmic division of 5cranial nerves , ophthalmic division of 5thth cranialcranial nerve & 6nerve & 6thth cranial nervecranial nerve ----N.B. >> The cavernous sinuses are united by the intercavernousN.B. >> The cavernous sinuses are united by the intercavernous sinuses which surround the pituitary gland ant. , post. & infsinuses which surround the pituitary gland ant. , post. & inf..
  • 53. --Sella turicicaSella turicica:: **It is a superior saddle shaped formation on the intracranial aspect of the body ofIt is a superior saddle shaped formation on the intracranial aspect of the body of sphenoid bone containing pituitary glandsphenoid bone containing pituitary gland **Boundaries : ant. >> ant. Clinoid processBoundaries : ant. >> ant. Clinoid process post. >> post. Clinoid processpost. >> post. Clinoid process lat. >> cavernous sinuslat. >> cavernous sinus **AnatomyAnatomy:: The seat of the saddle is known as the hypophyseal fossa, which holds theThe seat of the saddle is known as the hypophyseal fossa, which holds the pituitary gland. The hypophyseal fossa is located in a depression in the bodypituitary gland. The hypophyseal fossa is located in a depression in the body of the sphenoid bone. Located anteriorly to the hypophyseal fossa is theof the sphenoid bone. Located anteriorly to the hypophyseal fossa is the tuberculum sellae ( optic foramen lies on either sides of ittuberculum sellae ( optic foramen lies on either sides of it(( Completing the formation of the saddle posteriorly is the dorsum sellae which isCompleting the formation of the saddle posteriorly is the dorsum sellae which is continuous with the clivus, inferoposteriorly. The dorsum sellae is terminatedcontinuous with the clivus, inferoposteriorly. The dorsum sellae is terminated laterally by the posterior clinoid processlaterally by the posterior clinoid process..
  • 54.
  • 55.
  • 56.
  • 57.
  • 58. --Arterial supplyArterial supply:: ICAICA **Sup. Hypophyseal arteriesSup. Hypophyseal arteries **Inf. Hypophyseal arteriesInf. Hypophyseal arteries --Venous drainageVenous drainage:: To cavernous & inter-cavernosal sinusesTo cavernous & inter-cavernosal sinuses
  • 59. --Radiological featuresRadiological features:: 11--Skull radiographySkull radiography<<<< Lateral viewLateral view 22--CT & MRICT & MRI<<<< **Best on sagittal & coronalBest on sagittal & coronal **Post. Pituitary appears high signal intensity on unenhanced T1 WIsPost. Pituitary appears high signal intensity on unenhanced T1 WIs **Dura above the sella must be horizontal not convexDura above the sella must be horizontal not convex --Infundibulum diameter should be not bigger than the adjacent basilar arteryInfundibulum diameter should be not bigger than the adjacent basilar artery **Sella itself is delineated bySella itself is delineated by:: Signal void of the bony cortexSignal void of the bony cortex High intensity signal of marrow in the clivusHigh intensity signal of marrow in the clivus **Optic nerves,chiasm & ICA vessels above & sphenoid sinus below seen clearlyOptic nerves,chiasm & ICA vessels above & sphenoid sinus below seen clearly on coronal sectionson coronal sections
  • 60.
  • 61.
  • 62.
  • 63.
  • 64.
  • 65. Limbic lobeLimbic lobe --This is not an anatomical lobe as such but functionally relatedThis is not an anatomical lobe as such but functionally related structures that surrounds the corpus callosum on the medialstructures that surrounds the corpus callosum on the medial surface of the cerebral hemispheresurface of the cerebral hemisphere --It includesIt includes:: Cingulate gyrusCingulate gyrus Splenial gyrusSplenial gyrus Parahippocampal gyrusParahippocampal gyrus HippocampusHippocampus Dentate gyrusDentate gyrus fornixfornix
  • 66.
  • 67. --The cingulate gyrus curves around the genu & body ofThe cingulate gyrus curves around the genu & body of CC and continues around the splenium as splenial gyrusCC and continues around the splenium as splenial gyrus >> this in turn is continuous with dentate gyrus &>> this in turn is continuous with dentate gyrus & hippocampushippocampus --Hippocampus >> is a curved elevation in the floor of theHippocampus >> is a curved elevation in the floor of the inf. Horn of the lateral ventricleinf. Horn of the lateral ventricle --Fornix >> is an efferent pathway from the hippocampusFornix >> is an efferent pathway from the hippocampus to the mamillary bodiesto the mamillary bodies
  • 68.
  • 69. BrainstemBrainstem --Connects the cerebral hemispheres to the spinalConnects the cerebral hemispheres to the spinal cord , extends from just above the tentorialcord , extends from just above the tentorial hiatus to just below the foramen magnumhiatus to just below the foramen magnum --It is bounded ant. By the clivus-basisphenoidIt is bounded ant. By the clivus-basisphenoid above & the basiocciput belowabove & the basiocciput below --has three parts : midbrain , pons & medullahas three parts : midbrain , pons & medulla
  • 70.
  • 71. **MidbrainMidbrain:: --Anteriorly two cerebral peduncles are seen separated theAnteriorly two cerebral peduncles are seen separated the interpeduncular fossainterpeduncular fossa --The post. Surface of the midbrain presents four roundedThe post. Surface of the midbrain presents four rounded prominences ( the corpora quadrigemina or the sup. &prominences ( the corpora quadrigemina or the sup. & inf. Colliculiinf. Colliculi( ,( , each sup. Colliculus >> lateral geniculate body of theeach sup. Colliculus >> lateral geniculate body of the optic tractoptic tract Each inf. Colliculus >> medial geniculate body of theEach inf. Colliculus >> medial geniculate body of the auditory systemauditory system
  • 72. --Cerebral peduncles have a ventral part , the crusCerebral peduncles have a ventral part , the crus cerebri and a dorsal part , the tegmentum , thesecerebri and a dorsal part , the tegmentum , these are separated by the substantia nigraare separated by the substantia nigra --The part of the midbrain posterior to theThe part of the midbrain posterior to the aqueduct is called the tectum or quadrigeminalaqueduct is called the tectum or quadrigeminal plateplate --Cranial nerves >> 3Cranial nerves >> 3rdrd & 4& 4thth cranial nervescranial nerves --Blood supply >> Sup. cerebellarBlood supply >> Sup. cerebellar
  • 73.
  • 74. **PonsPons:: --A shallow groove is seen in the midline , the basilar arteryA shallow groove is seen in the midline , the basilar artery may lie in this groove , but often lies lateral to itmay lie in this groove , but often lies lateral to it --The post. Surface of the pons forms the upper part ofThe post. Surface of the pons forms the upper part of the floor of the 4the floor of the 4thth ventricleventricle --Cranial nerves >> 5Cranial nerves >> 5thth & 6& 6thth cranial nervescranial nerves 77thth & 8& 8thth cranial nerves emerges at the junction with thecranial nerves emerges at the junction with the medulla laterally >> CPA ( cerebello-pontine anglemedulla laterally >> CPA ( cerebello-pontine angle(( --Blood supply >> pontine branches of the basilar ABlood supply >> pontine branches of the basilar A
  • 75.
  • 76. **Medulla oblongataMedulla oblongata:: --Ant. The ventral median fissure is deep in its superior part , a ridgeAnt. The ventral median fissure is deep in its superior part , a ridge on each side of this fissure is formed by the pyramidal fibers andon each side of this fissure is formed by the pyramidal fibers and is called the pyramid , lateral to the pyramid in the upper medullais called the pyramid , lateral to the pyramid in the upper medulla is an oval bulge called the olive , lateral to the olive lies the inf.is an oval bulge called the olive , lateral to the olive lies the inf. Cerebellar peduncle joining the medulla to the cerebellumCerebellar peduncle joining the medulla to the cerebellum --Post. The upper part of the medulla is open in the floor of the 4Post. The upper part of the medulla is open in the floor of the 4thth ventricleventricle --Cranial nerves >> 9Cranial nerves >> 9thth , 10, 10thth , 11, 11thth & 12& 12thth cranial nervescranial nerves --blood supply >> ant. Part : vertebral & basilarblood supply >> ant. Part : vertebral & basilar post. Part : PICApost. Part : PICA
  • 77.
  • 78. CerebellumCerebellum --The cerebellum lies in the post. Fossa , it is separated from theThe cerebellum lies in the post. Fossa , it is separated from the occipital lobe by the tentorium & from the the pons andoccipital lobe by the tentorium & from the the pons and midbrain by the 4midbrain by the 4thth VV --It is connected to the brainstem by 3 pairs of cerebellar pedunclesIt is connected to the brainstem by 3 pairs of cerebellar peduncles:: Sup. Cerebellar peduncles to the midbrainSup. Cerebellar peduncles to the midbrain Middle Cerebellar peduncles to the ponsMiddle Cerebellar peduncles to the pons Inf. Cerebellar peduncles to the medullaInf. Cerebellar peduncles to the medulla --There are 2 hemispheres with the midline vermis betweenThere are 2 hemispheres with the midline vermis between
  • 79. --The hemispheres >> on each side below the middle cerebellarThe hemispheres >> on each side below the middle cerebellar peduncle is the folliculus , the tonsils are the most ant. Inf. Partpeduncle is the folliculus , the tonsils are the most ant. Inf. Part of the hemispheres and lie close to the midlineof the hemispheres and lie close to the midline --The vermis >> is the narrow midline portion of the cerebllum ,The vermis >> is the narrow midline portion of the cerebllum , sup. There is a low median elevation not clearly separated fromsup. There is a low median elevation not clearly separated from the hemispheres , however inf. The vermis is quite separate &the hemispheres , however inf. The vermis is quite separate & lies in a deep cleft called the vallecula , the most ant. Part of thelies in a deep cleft called the vallecula , the most ant. Part of the sup. Vermis is the lingula , which lies on the sup. Medullarysup. Vermis is the lingula , which lies on the sup. Medullary vilumvilum ))a thin sheet of white matter between the sup. Cerebellar pedunclesa thin sheet of white matter between the sup. Cerebellar peduncles ) , the most ant. Part of the inf. Vermis is the nodule) , the most ant. Part of the inf. Vermis is the nodule
  • 80. --SubdivisionsSubdivisions:: Ant. LobeAnt. Lobe Post. LobePost. Lobe Flocculonodular lobeFlocculonodular lobe --Arterial supplyArterial supply:: PICA from the vertebralPICA from the vertebral AICA from the basilarAICA from the basilar Sup. Cerebellar arteries from basilar ASup. Cerebellar arteries from basilar A --Venous drainageVenous drainage:: Precentral cerebellar vein & the sup. Vermian vein drain to the great cerebral veinPrecentral cerebellar vein & the sup. Vermian vein drain to the great cerebral vein Remaining of the cerebellar vein >> nearby dural sinusesRemaining of the cerebellar vein >> nearby dural sinuses ))straight , transverse , inf. Petrosal , sigmoid & occipital sinusesstraight , transverse , inf. Petrosal , sigmoid & occipital sinuses(( N.B. >> the normal floculus enhances more than the rest of the cerebellum , shouldnotN.B. >> the normal floculus enhances more than the rest of the cerebellum , shouldnot be mistaken for a more ant. Located acoustic neuromabe mistaken for a more ant. Located acoustic neuroma
  • 81. A. Frontal Lobe B. Frontal Bone )Superior Surface of Orbital Part( C. Dorsum Sellae D. Basilar Artery E. Temporal Lobe F. Mastoid Air Cells G. Cerebellar Hemisphere
  • 82. A. Falx Cerebri B. Frontal Lobe C. Anterior Horn of Lateral Ventricle D. Third Ventricle E. Quadrigeminal Plate Cistern F. Cerebellum
  • 83. MeningesMeninges --Three layers of meninges cover the brain & spinal cord >> dura ,Three layers of meninges cover the brain & spinal cord >> dura , arachnoid & piaarachnoid & pia **Dura materDura mater:: --Two layers , outer layer which is the periosteum of the inner aspectTwo layers , outer layer which is the periosteum of the inner aspect of the skull , the inner layer is the dura mater properof the skull , the inner layer is the dura mater proper --Falx cerebri >> sickle-shaped dural septum in the median sagittalFalx cerebri >> sickle-shaped dural septum in the median sagittal plane attached to the crista galli in the midline of the floor of theplane attached to the crista galli in the midline of the floor of the ant. Cranial fossa & along the midline of the inner aspect of theant. Cranial fossa & along the midline of the inner aspect of the vault of the skull to the margins of the SSSvault of the skull to the margins of the SSS
  • 84. --Diaphragma sellae >> is a horizontal fold of dura thatDiaphragma sellae >> is a horizontal fold of dura that almost completely covers the pituitary fossa , with aalmost completely covers the pituitary fossa , with a small opening for the pituitary stalksmall opening for the pituitary stalk --Tentorium cerebelli >> is a horizontal septum of duraTentorium cerebelli >> is a horizontal septum of dura mater that separates the occipital lobes from themater that separates the occipital lobes from the superior surface of the cerebellumsuperior surface of the cerebellum --Falx cerebelli >> is a low elevation of dura that projectsFalx cerebelli >> is a low elevation of dura that projects a small distance into the cerebellar interhemispherica small distance into the cerebellar interhemispheric fissurefissure
  • 85. **Arachnoid materArachnoid mater:: --Delicate membrane which is impermeable to CSF , itDelicate membrane which is impermeable to CSF , it lines the dura matter separated from it only by a thinlines the dura matter separated from it only by a thin layer of lymph in the subdural ( potential spacelayer of lymph in the subdural ( potential space(( --It is separated from the pia mater by the subarachnoidIt is separated from the pia mater by the subarachnoid space , which contains the CSFspace , which contains the CSF --Arachnoid mater herniates through holes in the dura intoArachnoid mater herniates through holes in the dura into the venous sinuses & venous lakes as arachnoid villi >>the venous sinuses & venous lakes as arachnoid villi >> CSF absorptionCSF absorption
  • 86. **Pia materPia mater:: --Closely adherent to the brain surfaceClosely adherent to the brain surface --It invaginates with with the choroid vessels intoIt invaginates with with the choroid vessels into the ventricles , & the layer of pia mater &the ventricles , & the layer of pia mater & ependyma together thus formed over theseependyma together thus formed over these vessels is called >> tela choroidea of thevessels is called >> tela choroidea of the ventriclesventricles
  • 87.
  • 88. --Arterial supply of the meningesArterial supply of the meninges:: **MMA ( middle meningeal arteryMMA ( middle meningeal artery(( branch of the maxillary artery that enters the the cranium through foramenbranch of the maxillary artery that enters the the cranium through foramen spinosum , it passes laterally in the floor of the middle cranial fossa , thenspinosum , it passes laterally in the floor of the middle cranial fossa , then superiorly & anteriorly along the greater wing of sphenoid , where it dividessuperiorly & anteriorly along the greater wing of sphenoid , where it divides into ant. & post. Branchesinto ant. & post. Branches **Additional supplyAdditional supply<<<< --Ant. Cranial fossa : meningeal branches of ophthalmic & ant. & post. EthmoidAnt. Cranial fossa : meningeal branches of ophthalmic & ant. & post. Ethmoid arteriesarteries --Cavernous sinus : meningeal branches of carotid artery & the accessoryCavernous sinus : meningeal branches of carotid artery & the accessory meningeal arterymeningeal artery --Post. Fossa : meningeal branches of vertebral arteryPost. Fossa : meningeal branches of vertebral artery --Nerve supply : 5Nerve supply : 5thth , 9, 9thth & 10& 10thth cranial nerves , with the dura around the foramencranial nerves , with the dura around the foramen magnum being innervated by C1-3 nervesmagnum being innervated by C1-3 nerves
  • 89.
  • 90. --Radiological featuresRadiological features:: **Extradural hematomaExtradural hematoma --Occurs when a vessel in the extradural space between dura and bone is torn byOccurs when a vessel in the extradural space between dura and bone is torn by trauma >> MMAtrauma >> MMA **Subdural hematomaSubdural hematoma --Also due to traumatic bleed in space between dura & arachnoid >> bridgingAlso due to traumatic bleed in space between dura & arachnoid >> bridging veinsveins --Subdural hematoma can extend into interhemispheric fissure & root of sylvianSubdural hematoma can extend into interhemispheric fissure & root of sylvian fissure on the brain surfacefissure on the brain surface **Subarachnoid hemorrhageSubarachnoid hemorrhage --In the subarachnoid space between the arachnoid & pia mater fromIn the subarachnoid space between the arachnoid & pia mater from spontaneous or traumatic rupture of an arteryspontaneous or traumatic rupture of an artery --Subarachnoid blood can then be seen in the cisterns & extending into sulci &Subarachnoid blood can then be seen in the cisterns & extending into sulci & fissures on the brain surface close to the site of bleedingfissures on the brain surface close to the site of bleeding
  • 91.
  • 92.
  • 93.
  • 94. **Skull radiographSkull radiograph:: --Dural calcification is common in older subjectsDural calcification is common in older subjects --Calcification of falx cerebri or of the tentorium can be seen in OF or FO viewsCalcification of falx cerebri or of the tentorium can be seen in OF or FO views **CT & MRICT & MRI:: --Above the level of the petrous temporal bone the cerebral hemispheres areAbove the level of the petrous temporal bone the cerebral hemispheres are separated from the cerebellum by the tentoriumseparated from the cerebellum by the tentorium --Best seen on contrast enhanced scans as it contains blood vesselsBest seen on contrast enhanced scans as it contains blood vessels --The tentorium is seen as high attenuation linear structure extending laterallyThe tentorium is seen as high attenuation linear structure extending laterally from the midbrain to the inner table of the skullfrom the midbrain to the inner table of the skull --The falx ccerebri is seen on higher cuts ant. & post. Extending into theThe falx ccerebri is seen on higher cuts ant. & post. Extending into the interhemispheric fissure almost to the corpus callosuminterhemispheric fissure almost to the corpus callosum