MACROMLECULAR
STRUCTURE AND BIOLOGICAL
FUNCTION OF PRIMARY
PROTIENS
PRESENTED BY
ATHIRA P
2ND SEM BPS
CBPST,KOCHI
CONTENTS
• Definition
• Types of protien
• Primary protiens
• Properties
• Functions
• Applications
WHAT IS PROTIENS
Protiens are the complex nitrogeneous organic
compounds in animal and plants.Proteins are
polymers of amino acids covalently linked
through peptide bonds into a chain.
TYPES OF PROTIEN
GLOBULAR PROTIENS
• They are thread like
molecule,lying side by side
to form fibers in fibrous
protien
• They serve as a chief
structural material of
animal tissue
• They are insoluble in
water,chemically inactive
FIBROUS PROTIENS
• In globular protien the
peptide chains are
folded,looped and twisted
• So molecule is more or less
spherical
• They are soluble in
water,chemically active
CLASSIFICATION OF PROTIENS
• Primary protiens
• Secondary protiens
• Teritiary protiens
• Quartanery structure
Primary Protiens
Linear arrangement of aminoacid group in
protiens is the primary structure .It is
formed by condensation reaction with
elimination of water molecule
PHSYCOCHEMICAL PROPERTIES
• water solubility depends on the structure
• Protiens are poor soluble in polar solvent
Like ETHANOL, insoluble in nonpolar
solvent
• Proteins form colloidal solutions
colloidal-osmotic pressure = onkotic
pressure
• Proteins can be salting-out of the solution
• Protiens are ampholytes
-COOH -COO- + H+
-NH2 + H+ -NH3+
• proteins strongly absorb UV radiation
• •proteins can be denaturated
• heat, whipping, shaking, radiation
• strong pH changes, salt of heavy metals,
• organic solvents, detergents
FUNCTIONS
• ANTIBODIES
• ENZYMES
• HORMONS
• TRANSPORT
• STORAGE
• STRUCTURAL PROTIEN
• CONTRACTILE PROTIEN
APPLICATIONS
• COATINGS
• FILMS IN FOOD PACKAGING
• Biotechnology industry protein precipitation
is used to eliminate contaminants commonly
contained in blood.
• Used in many foods
• Protien microchip isused as biomarker to
identify the tumer cells
• Biomedical application :-
hydrogel,scaffold,nanofiber,nanoparticles
• Target drug delivery protien system
SOME APPLICATIONS
Macromolecular structure and biological function of primary protiens

Macromolecular structure and biological function of primary protiens

  • 1.
    MACROMLECULAR STRUCTURE AND BIOLOGICAL FUNCTIONOF PRIMARY PROTIENS PRESENTED BY ATHIRA P 2ND SEM BPS CBPST,KOCHI
  • 2.
    CONTENTS • Definition • Typesof protien • Primary protiens • Properties • Functions • Applications
  • 3.
    WHAT IS PROTIENS Protiensare the complex nitrogeneous organic compounds in animal and plants.Proteins are polymers of amino acids covalently linked through peptide bonds into a chain.
  • 4.
    TYPES OF PROTIEN GLOBULARPROTIENS • They are thread like molecule,lying side by side to form fibers in fibrous protien • They serve as a chief structural material of animal tissue • They are insoluble in water,chemically inactive FIBROUS PROTIENS • In globular protien the peptide chains are folded,looped and twisted • So molecule is more or less spherical • They are soluble in water,chemically active
  • 5.
    CLASSIFICATION OF PROTIENS •Primary protiens • Secondary protiens • Teritiary protiens • Quartanery structure
  • 6.
    Primary Protiens Linear arrangementof aminoacid group in protiens is the primary structure .It is formed by condensation reaction with elimination of water molecule
  • 9.
    PHSYCOCHEMICAL PROPERTIES • watersolubility depends on the structure • Protiens are poor soluble in polar solvent Like ETHANOL, insoluble in nonpolar solvent • Proteins form colloidal solutions colloidal-osmotic pressure = onkotic pressure • Proteins can be salting-out of the solution • Protiens are ampholytes -COOH -COO- + H+ -NH2 + H+ -NH3+
  • 10.
    • proteins stronglyabsorb UV radiation
  • 11.
    • •proteins canbe denaturated • heat, whipping, shaking, radiation • strong pH changes, salt of heavy metals, • organic solvents, detergents
  • 12.
    FUNCTIONS • ANTIBODIES • ENZYMES •HORMONS • TRANSPORT • STORAGE • STRUCTURAL PROTIEN • CONTRACTILE PROTIEN
  • 13.
    APPLICATIONS • COATINGS • FILMSIN FOOD PACKAGING • Biotechnology industry protein precipitation is used to eliminate contaminants commonly contained in blood. • Used in many foods • Protien microchip isused as biomarker to identify the tumer cells
  • 14.
    • Biomedical application:- hydrogel,scaffold,nanofiber,nanoparticles • Target drug delivery protien system
  • 15.