The document provides detailed information on the anatomy of the liver based on CT imaging. It describes the liver's location, lobes and segments. It discusses the liver's vasculature including the hepatic artery, portal vein and hepatic veins. It also describes the bile ducts and variants. The document outlines the CT appearance of the liver in different phases following contrast administration and the technique for CT liver volumetry.

1. CT ANATOMY OF LIVER

2. • Liver is the largest abdominal
organ. Mean weight :1.5- 1.8Kg.
• Transverse diameter : 20-23cm.
Craniocaudal measurement at
midpoint of right lobe : 13- 16cm.
• Surrounded by Glisson’s capsule –
Dense fibrous sheath with
interspersed elastic fibres

3. • Liver has five surfaces: superior,
anterior, right, posterior and
inferior.
• The inferior surface is separated
by acute inferior margin of the
liver.

4. • The anterior surface include the
falciform ligament which runs on
a vertical plane slightly to the
right from the abdominal
midline.midline

5. • The inferior surface of the liver is
divided into four sectors by
structures which assume the shape
of a “H”.
• The left vertical arm of the H -
ligamentum teres anteriorly and the
ligamentum venosum posteriorly.
• The horizontal portion of the H- liver
hilum - porta hepatis.
• The vertical right arm of the H- the
inferior vena cava posteriorly and the
gallbladder fossa anteriorly.

6. • In the region between the two vertical arms of the H, the two
accessory lobes are recognisable, the caudate lobe posteriorly and the
quadrate lobe anteriorly
• The medial aspect of the inferior caudate lobe is known as papillary
process

8. • On the inferior liver surface, there are some impressions of adjacent
abdominal organs.
• Esophagus, right anterior part of stomach, duodenum, gall bladder,
right colic flexure, right kidney ,right suprarenal gland
• The left lobe portion cranial to lesser curvature of the stomach, does
not receive impression by adjacent organs - is known as tuber
omentale.

12. LIGAMENTS
• Falciform ligament
• Ligamentum teres
• Ligamentum venosum
• Lesser omentum
• Right and left triangular ligament
• Anterior and posterior coronary ligament

13. • FALCIFORM LIGAMENT:
-Sickle shaped
- Anteriorly connects with peritoneum behind the right rectus
abdominis
- Posteriorly, in contact with left lobe of liver.
- Free edge contain ligamentum teres
- Divides the subphrenic compartment into right and left

16. • Ligamentum teres or Round
ligament: Formed by obliterated
fetal umbilical vein
• Ligamentum venosum: Formed
by obliterated ductus venosus.
Spans from porta hepatis of the
liver to the inferior venacava.

18. BARE AREA OF LIVER
• Anterior boundary: Anterior
coronary ligament
• Posterior boundary: Posterior
coronary ligament
• Where the coronary ligaments
meet laterally, they form right
and left triangular ligaments

19. • Morphological division:
-Two main lobes - the right and
the left one
-Two accessory lobes - the
caudate and the quadrate lobes
- Divided into right and left lobes
by fossae of gall bladder and
inferior venacava.

20. SEGMENTAL ANATOMY OF LIVER
• The French surgeon and anatomist Claude Couinaud divided the liver
into eight functionally independent segments
• allows resection of segments without damaging other segments.
• Each segment has its own vascular inflow, outflow and biliary
drainage.
• In the centre of each segment there is a branch of the portal vein,
hepatic artery and bile duct.
• In the periphery of each segment there is vascular outflow through
the hepatic veins.

21. • Liver is divided into a functional
left and right liver by a main
scissurae containing the middle
hepatic vein.
• This is known as Cantlie's line.
• Cantlie's line runs from the
middle of the gallbladder fossa
anteriorly to the inferior vena
cava posteriorly.

22. • Right hepatic vein divides the
right lobe into anterior and
posterior segments.
• Left hepatic vein divides the left
lobe into left medial and left
lateral sections.
• The portal vein divides the liver
horizontally into upper and lower
segments.

23. • There are eight liver segments.
• Segment IV is divided into segment IVa and IVb according to Bismuth.
• The numbering of the segments is in a clockwise manner.
• Segment I (the caudate lobe) is located posteriorly.
• It is not visible on a frontal view.

24. Transverse anatomy
This figure is a transverse
image through the
superior liver segments,
that are divided by the
right and middle hepatic
veins and the falciform
ligament.

25. This is a transverse image at the level
of the left portal vein.
At this level the left portal vein divides
the left lobe into the superior
segments (II and IVa) and the inferior
segments (III and IVb).
The left portal vein is at a higher level
than the right portal vein.

26. This image is at the level of the
right portal vein.
At this level the right portal
vein divides the right lobe of
the liver into superior segments
(VII and VIII) and the inferior
segments (V and VI).
The level of the right portal
vein is inferior to the level of
the left portal vein.

27. At the level of the splenic
vein, which is below the
level of the right portal
vein, only the inferior
segments are visible.

28. CAUDATE LOBE
• The caudate lobe or segment I is anatomically different from other
lobes in that it has direct connections to the IVC.
• The caudate lobe may be supplied by both right and left branches of
the portal vein.
• bounded posterolaterally by the fossa for the inferior vena cava,
anteriorly by the ligamentum venosum, and inferiorly by the porta
hepatis
• its inferior portion is subdivided into a lateral caudate process and a
medial papillary process

30. Above portal vein

39. PORTA HEPATIS
• The porta hepatis/ hilum of the liver -
passes across the left posterior aspect
of visceral surface of the right lobe of
the liver.
• It separates the caudate lobe and
process from the quadrate lobe.
• The porta hepatis transmits the portal
triad—formed by the main portal
vein, proper hepatic artery, and
common hepatic duct—as well as
nerves and lymphatics.
• All of these structures are enveloped
in the free edge of the lesser
omentum or hepatoduodenal
ligament.

41. LIVER VASCULAR SYSTEM
• Around 25% of hepatic blood inflow is arterial and is supplied by the
common hepatic artery (CHA).
• Portal vein supplies ~75% of the liver's blood supply by volume.
• Most of the venous drainage from the liver passes into the three
hepatic veins which drain into the inferior vena cava.

43. HEPATIC ARTERY
• At the liver hilum, before entering the
parenchyma, the hepatic artery bifurcates
into the right and left hepatic branches.
• The right hepatic artery (RHA) is larger, gives
off a cystic branch for the gallbladder and
bifurcates into anterior and posterior
branches just before entering the
parenchyma.
• The left branch divides into three vessels for
the anterior, posterior and caudate parts of
the left lobe.
• Hepatic arteries then give off segmental and
subsegmental arteries that run and branch
in the portal spaces.

46. PORTAL VENOUS SYSTEM
• It originates by the confluence
between the superior mesenteric
vein and the splenic vein behind the
neck of the pancreas (L2).
• The PV is valveless , has a length of
around 70 mm.
• Diameter 13 mm is considered as the
upper limit.
• It runs in the hepatoduodenal
ligament along with the common bile
duct and the hepatic artery.

47. • Immediately before reaching the liver, the
portal vein divides in the porta hepatis
into left and right portal veins.
• The right portal vein divides into anterior
(supplying segments 5 and 8) and
posterior (supplying segments 6 and 7)
branches.
• The left portal vein may be divided into
transverse and umbilical portions.
• The main branches of the left portal vein
originate from the umbilical portion, and
supply liver segments 2, 3 and 4

50. HEPATIC VEINS
• Venous blood of the liver is mainly
collected by the hepatic veins, which
drain into the IVC.
• Has three main venous branches: the
left, the right and the middle one.
• Hepatic veins are not encompassed
by a surrounding connective tissue
sheath, as their tunica adventitia is in
direct contact with the liver
parenchyma

52. BILE DUCT
• Bile collected by the bile canaliculi converges towards the portal triad,
where bile ducts are seen.
• Smaller bile ducts converge with one another to form right and left
hepatic ducts.
• The left duct collects bile from the individual segments of the left liver
• The right has two tributaries, the right posterior hepatic duct (RPHD)
and the right anterior hepatic duct (RAHD)
• RHD and LHD converge to form the common hepatic duct (CHD) which
exits the liver at the hilum.
• The common hepatic duct receives the cystic duct, thus becoming the
common bile duct and opens into major duodenal papilla.
• Bile duct from S1 can drain into RHD or LHD

55. INTRAHEPATIC BILE DUCT VARIANTS
Huang’s classification
• A1 refers to the standard
configuration.
• A2- triple confluence between the
RPHD, RAHD and LHD.
• A3 -RPHD or RAHD joins the LHD
• A4 - RPHD joins the CHD
• A5 – RPHD joins the cystic duct.

56. • B1 is standard configuration- duct from S2 and S3 forming a common
duct which joins S4.
• B2- Duct from S4 drains into the RHD.
• B3 – Duct from S4 drains into RAHD.
• B4 – Duct from S4 drains into CHD.
• B5 - S2 and S3 have independent drainage
• B6 - S1 drains in the CHD.

57. MORPHOLOGY VARIANTS
• Riedel’s lobe is a morphological
variant of the right hepatic lobe,
which is tongue like extension in
the craniocaudal dimension,
extending inferiorly beyond the
limit of the costal cartilage.

58. • Beaver tail liver- Here left lobe is
developed in the latero-lateral
dimension, and thus spans
further in the left
hypochondrium, making
extensive contact with the
spleen.

59. • Diaphragmatic invagination in
the liver.
• As a result of invagination of the
diaphragmatic slips along the
superior aspect of the liver,
pseudoaccessory fissures are
formed.

61. • On unenhanced CT normal liver parenchyma has homogeneous
density, which can vary between 55 and 65 HU.
• Exceeds that of the spleen by about 10HU.
• Increased diffuse deposition of fat leads to reduction in attenuation
• Increased glycogen – increased attenuation

62. • Hepatic perfusion cycle can be differentiated into three phases.
1. Arterial phase
2. Redistribution or portal venous phase
3. Equilibrium or hepatic venous phase
Bolus tracking is done and when aortic enhancement reaches a
threshold of approximately 150HU, hepatic scanning is initiated.

63. • Early arterial phase – Approx 10 sec after contrast threshold based
scanning initiation.
Contrast enhancement of the abdominal aorta and hepatic artery
without admixture of enhanced portal venous blood

64. • Late arterial phase : Approx 20
sec after scanning initiation.
- Clear depiction of hepatic artery
and its branches.
- Minimal admixture of enhanced
portal venous blood

65. • Redistribution/ portal venous
inflow phase : About 30 sec after
scan initiation.
- Allows early visualisation of
portal vein and its intrahepatic
branches.
- Maximum contrast enhancement
after 40sec.

66. • Hepatic venous phase: 60 sec
after scan initiation.
- Simultaneous enhancement of
hepatic and portal veins will be
visualised.

67. • Delayed phase : 10-15min after initiation of contrast. Done in
suspected cholangiocarcinoma.

69. LIVER VOLUMETRY
• CT liver volumetry is an essential imaging study in preoperative
assessment for living donor liver transplantation.
• Hepatic venous phase is used for CT volumetry. 6 or 8 mm slice
thickness used.
• Liver boundary is traced to exclude the surrounding structures/organs as
well as vessels and hepatic fissures, then we summate the liver area on
every single cut
• Virtual hepatectomy plane is drawn on each cut on axial images, to the
right of the middle hepatic vein in right hemihepatectomy and along
falciform ligament in left lateral segmentectomy
• Volume of all cuts is summed to get the total and lobar volume of the
liver