What is MIS?
A minimally invasive medical procedure is defined as one that is carried out by entering the body through the skin or through a body cavity or anatomical opening, but with the smallest damage possible to these struct uresIncludes laparoscopic, endoscopic, and other approaches.
Why MIS?
Decreased patient pain
Decreased patient recovery period
Possible decrease in inflammatory response in the patient which may prove to have a better outcome in oncologic operations.
Distant future
In the distant future, there will be a para- digm shift with the development of non-inva- sive surgical techniques in combination with nanotechnologies and a new era in the devel- opment of surgery, and subsequently in surgi- cal techniques, will be opened.
Nanotechnology is an umbrella term for materials and devices that operate at the nanoskill (1 billionth of a meter). In terms of scale, a nanometer is approximately one 1/8000 of a human hair or 10 times the diam- eter of a hydrogen atom. The size of the device can vary but starts from a ten thou- sand-logic element system that will occupy a cube of no more than one hundred nanome- ters. This is a volume slightly larger than 0.001 cubic microns. This would be sufficient to hold a small computer. For example, if red blood cells are approximately eight microns in diameter, the 100 nanomicroprocessor will be 80 times smaller than a red blood cell. Devices this size could easily fit into the circulatory system and could even conceivably enter indi- vidual cells.
This presentation of introduction of laparoscopic surgery made by Dr. R.K. Mishra Director and chief surgeon World Laparoscopy Hospital. Dr. Mishra in this presentation has explained present pas and future of laparoscopic surgery. Laparoscopy is a surgical procedure which uses a special surgical instrument called a laparoscope to look inside the body, or to perform certain operations. World Laparoscopy Hospital is the center of excellence for laparoscopic and da vinci robotic surgery training and considered as one of the best institute in the world. For more detail about laparoscopic surgery please visit: http://www.laparoscopyhospital.com
It has not changed the nature of disease
The basic principles of good surgery still apply,including appropriate case selection, excellent exposure,adequate retraction and a high level technical expertise
If a procedure makes no sense with conventional access, it will make no sense with a minimal access approach
The cleaner and gentler the act of operation, the less the patient suffers, the smoother and quicker his convalescence,the more exquisite his healed wound.
We actually do not know what is there stored for us, but we believe that laparoscopy is trending towards advancement and nano and robotic technology is going to replace in future.
3D cameras have come into existence and various newer technologies are being invented.
LAPAROSCOPIC HAND INSTRUMENTS, ACCESSORIES AND ERGONOMICSsinghanubhav5
EXTENSIVE COVERAGE OF LAPAROSCOPIC INSTRUMENTS AND THEIR ERGONOMICS TO HELP SURGEONS TO KNOW HOW TO USE THEIR LAP INSTRUMENTS IN MOST APPROPRIATE WAY AND THEIR ERGONOMICS TO BE COMFERTABLE DURING SURGERY AND PATIENTS LIFE ALSO MORE SAFE.
This presentation of introduction of laparoscopic surgery made by Dr. R.K. Mishra Director and chief surgeon World Laparoscopy Hospital. Dr. Mishra in this presentation has explained present pas and future of laparoscopic surgery. Laparoscopy is a surgical procedure which uses a special surgical instrument called a laparoscope to look inside the body, or to perform certain operations. World Laparoscopy Hospital is the center of excellence for laparoscopic and da vinci robotic surgery training and considered as one of the best institute in the world. For more detail about laparoscopic surgery please visit: http://www.laparoscopyhospital.com
It has not changed the nature of disease
The basic principles of good surgery still apply,including appropriate case selection, excellent exposure,adequate retraction and a high level technical expertise
If a procedure makes no sense with conventional access, it will make no sense with a minimal access approach
The cleaner and gentler the act of operation, the less the patient suffers, the smoother and quicker his convalescence,the more exquisite his healed wound.
We actually do not know what is there stored for us, but we believe that laparoscopy is trending towards advancement and nano and robotic technology is going to replace in future.
3D cameras have come into existence and various newer technologies are being invented.
LAPAROSCOPIC HAND INSTRUMENTS, ACCESSORIES AND ERGONOMICSsinghanubhav5
EXTENSIVE COVERAGE OF LAPAROSCOPIC INSTRUMENTS AND THEIR ERGONOMICS TO HELP SURGEONS TO KNOW HOW TO USE THEIR LAP INSTRUMENTS IN MOST APPROPRIATE WAY AND THEIR ERGONOMICS TO BE COMFERTABLE DURING SURGERY AND PATIENTS LIFE ALSO MORE SAFE.
Slideshow of Laparoscopic Surgery by Prof. R.K. Mishra Prof. R.K. Mishra has the distinction of being first Asian who is honoured as Professor of Minimal Access Surgery by legislated University of Govt. of India. He is is currently the most experienced professor of minimal surgery in the world who has alone as a single faculty trained more than 3000 surgeon and gynaecologists from 108 countries. http://www.laparoscopyhospital.com/drrkmishra.htm
This presentation will help u know with the history,present and coming up trends in laparoscopy .Also it is an acquaintance presentation regarding laparoscopy.
Laparoscopic Surgery Training at World laparoscopy hospitalrkmishra14
Laparoscopic Surgery is now a days necessity and its training is essential. For laparoscopic training contact http://www.laparoscopyhospital.com/online_application_for_laparoscopy.htm
Slideshow of Laparoscopic Surgery by Prof. R.K. Mishra Prof. R.K. Mishra has the distinction of being first Asian who is honoured as Professor of Minimal Access Surgery by legislated University of Govt. of India. He is is currently the most experienced professor of minimal surgery in the world who has alone as a single faculty trained more than 3000 surgeon and gynaecologists from 108 countries. http://www.laparoscopyhospital.com/drrkmishra.htm
This presentation will help u know with the history,present and coming up trends in laparoscopy .Also it is an acquaintance presentation regarding laparoscopy.
Laparoscopic Surgery Training at World laparoscopy hospitalrkmishra14
Laparoscopic Surgery is now a days necessity and its training is essential. For laparoscopic training contact http://www.laparoscopyhospital.com/online_application_for_laparoscopy.htm
Model relacional i comprovació de la 1era , 2ona, 3era forma normal i la fòrmula normal Boyce-Codd. Transformació del model entitat relació al model relacional.
Il colangiocarcinoma: Presentazione Clinica, Diagnosi e Trattamento - Gastrol...Gastrolearning
Gastrolearning II modulo/8a lezione
Il colangiocarcinoma: Presentazione Clinica, Diagnosi e Trattamento
Prof. D. Alvaro - Università di Roma La Sapienza
Il trattamento chirurgico del colangiocarcinoma - Gastrolearning®Gastrolearning
Gastrolearning II modulo/8a lezione
Il trattamento chirurgico del colangiocarcinoma
Prof. Gian Luca Grazi - Hepato-Biliary-Pancreatic Surgery National Cancer Institute Regina Elena, Roma
Basics of laproscopic surgery..
by dr navdeep s kamboj presented at sgrdumsar amritsar.
topics covered--
1 basics of laparoscopy
2 lap cholecystectomy
3 lap appendixcectomy
pneumoperitonem
merits and demerits of laproscopy
ligasure
endoscopy,
laparoscopic instruments
Chronological Advances in Minimal Access Surgery..pdfAmzadHosen3
World Laparoscopy Hospital provides learning by doing. It provides real-world laparoscopic surgery experience by allowing the trainee to get hands-on directly with whatever surgeons are learning and developing a sense of empowerment. After taking this laparoscopic training course, surgeons and gynecologists can perform laparoscopic surgery them self on their patients with confidence.
https://www.laparoscopyhospital.com/SERV01.HTM
Hysteroscopy Newsletter is an opened forum to all professionals who want to contribute with their knowledge and even share their doubts with a word-wide gynecological
community
laparoscopy is recent advancing area in the field of general surgery. the identification and underlying mechanism of action of each laparoscopic instrument is necessary for their handling ans use.
Laparoscopy is an operation performed in the abdomen or pelvic area using small incisions, often less than 1.5 cm, with the assistance of a Laparoscopic camera, typically for gallbladder, colon, kidney, and other procedures. Before, if an operation had to be conducted in the belly, doctors had to cut open the area, hence the name laparotomy.
General x-ray machine and fluoroscopy
the presentation to medical workers
contain simple explanation about radiation protection in the radiology department
Laparoscopy is an innovative diagnostic and surgical tool in veterinary field. Laparoscopic surgeries revolutionizes the minimally invasive surgical approaches with less surgical trauma and faster recovery.
Similar to LAPAROSCOPIC SURGERY- PAST, PRESENT AND FUTURE (20)
Really putting such patients first means: 4 ensuring that such patients have continuity of care with a healthcare professional whom the patient knows and trusts; longer appointments as required;shared decision making and an agreed care plan; and easy access to care.
The presence of haematuria may be the sole symptom of an underlying disease, either benign or malignant. It is one of the most common presentations of patients with urinary tract diseases and of patients referred for urinary imaging. Painless visible haematuria (VH) is the commonest presentation of bladder cancer.
CBDSs are one of the medical conditions leading to surgical intervention. They may occur in 3%–14.7% of all patients for whom cholecystectomies are preformed. When patients present with CBD, the one important question that should be answered: what is the best modality of treatment under the giving conditions? There are competing technologies and approaches for diagnosing CBDS with regard to diagnostic performance characteristics, technical success, safety, and cost effectiveness. Management of CBDS usually requires two separate teams: the gastroenterologist and the surgical team. One of the main factors in the management is initially the detection of CBDS, before, during, or after cholecystectomy. The main options for treatment are pre- or postoperative ERCP with endoscopic biliary sphincterotomy (EST), laparoscopic or open surgical bile duct clearance. There are other options for the treat- ment of CBDS such as electrohydraulic lithotripsy (EHL), extracorporeal shockwave lithotripsy (ESWL), dissolving solutions, and laser lithotripsy. It is unlikely that one option
will be appropriate for all clinical circumstances in all centers. Variables such as disease status, patient demographics, availability of endoscopic, radiological and surgical expertise, and healthcare economics will all have significant influence on practice
The incidence of biliary injury after laparoscopic cholecystectomy (LC) has shown a declining trend though it may still be twice that as with open cholecystectomy. Major biliary or vasculobiliary injury is associated with significant morbidity. As prevention is the best strategy, the concept of a culture of safe cholecystectomy has been recently introduced to educate surgeons and apprise them of basic tenets of safe performance of LC. Various aspects of safe cholecystectomy include: (1) thorough knowledge of relevant anatomy, various anatomical landmarks, and anatomical variations; (2) an understanding of the mechanisms involved in biliary/vascular injury, the most important being the misidentification injury; (3) identification of various preoperative and intraoperative predictors of difficult cholecystectomy; (4) proper gallbladder retraction; (5) safe use of various energy devices; (6) understanding the critical view of safety, including its doublet view and documentation; (7) awareness of various error traps (e.g., fundus first technique); (8) use of various bailout strategies (e.g., subtotal cholecystectomy) in difficult gallbladder cases; (9) use of intraoperative imaging techniques (e.g., intraoperative cholangiogram) to ascertain correct anatomy; and (10) understanding the concept of time-out. Surgeons should be facile with these aspects of this culture of safety in cholecystectomy in an attempt to reduce the incidence of biliary/vascular injury during LC.
Ageing, also spelled aging, is the process of becoming older. The term refers especially to human beings, many animals, and fungi, whereas for example bacteria, perennial plants and some simple animals are potentially immortal. In the broader sense, ageing can refer to single cells within an organism which have ceased dividing (cellular senescence) or to the population of a species (population ageing).
In humans, ageing represents the accumulation of changes in a human being over time,[1] encompassing physical, psychological, and social change. Reaction time, for example, may slow with age, while knowledge of world events and wisdom may expand. Ageing is among the greatest known risk factors for most human diseases:[2] of the roughly 150,000 people who die each day across the globe, about two thirds die from age-related causes.
The causes of ageing are uncertain; current theories are assigned to the damage concept, whereby the accumulation of damage (such as DNA oxidation) may cause biological systems to fail, or to the programmed ageing concept, whereby internal processes (such as DNA methylation) may cause ageing. Programmed ageing should not be confused with programmed cell death (apoptosis).
As we enter in the Modern day, we are witnessing dawn of the new trend in which closed body operating procedures are more often being performed through minimal access. This development is the consequence of vision and work of many dedicated individuals. They include early pioneers of endoscopy who planted the seed and lastly the current pioneers who pushed and expanded these frontiers to give rise the birth of modern laparoscopy. Therapeutic laparoscopic surgery was introduced into the surgical practice recently and within a short span of time, it has become established as defacto standard for the treatment of chronic cholelithiasis and many advanced laparoscopic procedures can be performed safely. Laparoscopic surgery, what we should witness today, may be the culmination of over a hundred years of painstaking efforts from the number of pioneers within the fields of optics, instrumentation and video laparoscopic camera. Few advances in medicine occur in isolation. The innate human curiosity to peer within the body cavities can be traced back to ancient times. However, due to primitive technology and crude instruments, several ambitions were not realized. It is probably safe to say that first laparoscopy would not have been performed had it not been for the efforts of many physicians in 1800s to develop endoscope. The device developed by Theodore Stein in mid 1880 contains all the aspects of the current endoscopic documentation system. There was a crude endoscope and a high intensity light source. Illumination was made by continuously feeding a magnesium wire into an ignition chamber utilizing a clockwise mechanism. Light from this combustion was reflected to the tube utilizing a mirror. Finally the look was focused on to some photographic plate through coupling optics.
Constipation refers to bowel movements that are infrequent or hard to pass. Constipation is a common cause of painful defecation. Severe constipation includes obstipation (failure to pass stools or gas) and fecal impaction, which can progress to bowel obstruction and become life-threatening.
Constipation is a symptom with many causes. These causes are of two types: obstructed defecation and colonic slow transit (or hypo mobility). About 50 percent of people evaluated for constipation at tertiary referral hospitals have obstructed defecation. This type of constipation has mechanical and functional causes. Causes of colonic slow transit constipation include diet, hormonal disorders such as hypothyroidism, side effects of medications, and rarely heavy metal toxicity. Because constipation is a symptom, not a disease, effective treatment of constipation may require first determining the cause. Treatments include changes in dietary habits, laxatives, enemas, biofeedback, and in particular situations surgery may be required.
Constipation is common; in the general population rates of constipation varies from 2–30 percent. In elderly people living in care homes the rate of constipation is 50–75 percent.[4] In the United States expenditures on medications for constipation are greater than US$250 million per year.
The definition of constipation includes the following:
infrequent bowel movements (typically three times or fewer per week)
difficulty during defecation (straining during more than 25% of bowel movements or a subjective sensation of hard stools; straining in this context is a strong effort to push out stool often by holding one's breath and by pushing the respective muscles in the abdominal area hard), or
the sensation of incomplete bowel evacuation.
The Rome III criteria are widely used to diagnose chronic constipation, and are helpful in separating cases of chronic functional constipation from less-serious instances.
Another definition states that less than three bowel movements per week and straining on more than 75% of occasions represents constipation in clinical surveys.
The Ideal Suture Material
Can be used in any tissue
Easy to handle
Good knot security
Minimal tissue reaction
Unfriendly to bacteria
Strong yet small
Won’t tear through tissues
Cheap
USES:
To bring tissue edges together and speed wound healing (=tissue apposition)
Orthopedic surgery to help stabilize joints
Repair ligaments
Ligate vessels or tis
Robotic Surgery means computer/ Robotic assisted surgery.
It was developed to overcome the limitations of MAS and to enhance the capabilities of surgeons performing open Surgery History of Robotic surgery
The first robot to assist in surgery was the Arthrobot, which was developed and used for the first time in Vancouver in 1983.[43] Intimately involved were biomedical engineer, Dr. James McEwen, Geof Auchinleck, a UBC engineering physics grad, and Dr. Brian Day as well as a team of engineering students. The robot was used in an orthopaedic surgical procedure on 12 March 1984, at the UBC Hospital in Vancouver.
Over 60 arthroscopic surgical procedures were performed in the first 12 months, and a 1985 National Geographic video on industrial robots, The Robotics Revolution, featured the device. Other related robotic devices developed at the same time included a surgical scrub nurse robot, which handed operative instruments on voice command, and a medical laboratory robotic arm. A YouTube video entitled Arthrobot illustrates some of these in operation .
Pancreatitis is a dreaded condition associated with development of acute and sudden inflammation of the pancreas.
Pancreatic enzymes are released in the abdomen and cause inflammation by the damage from digestion of normal body structures, especially fat in the abdomen.
Mortality ranges from 3 percent in patients with interstitial edematous pancreatitis to 17 percent in patients who develop pancreatic necrosis.
Every upcoming surgeon practising minimal access surgery should know the basics of urology , so that he or she can put his or her,s capabilities as a surgeon
Common symptoms of depression:
Lost of interest in the things that were previously pleasurable
Depressed and Sadness
Hopelessness
Other may Include:
Anxiety
Increased feeling of guilt
Irritability
Impatience
Sleep disturbances
Tearfulness
Difficulty concentrating
Appetite changes (loss/gain)
Increased Isolation
Somatic Pain
Substance abuse
Laparoscopic Urologic surgery, is a part of the curriculum of Minimal Access Surgery, and requires lot of skills and patience. All new surgeons carrying out Basic Laparoscopic surgery should aim at also doing Lap. Urological surgeries, which has a steep learning curve, but with with excellent outcomes.
This presentation was delivered at Puri on 10th january 2015
on the occasion of annual Rotary District Conference along with IMA Puri. It highlights on metabolic syndrome and its surgical solution.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
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2. History of Laparoscopy
The first description dates to Hippocrates in
Greece, for use of a speculum to visualize
the rectum (460–375 BC).
A three bladed speculum was found in the ruins
of Pompeii*.
*A roman town buried by a volcano eruption
near modern Naples, Italy - 79 AD).
3. History of Laparoscopy
1806: Philip Bozzini developed an
instrument called a Lichtleiter
(light-guiding instrument)
1853: Antoine Jean Desormeaux
used Bozzini’s Lichtleiter
1867: Desormeaux used an open
tube to examine the genitourinary
tract
4. History of Laparoscopy
Maximilian Nitze (1848 – 1906)
invented the first cystoscope
(Nitze-Leiter cystoscope) using an
electrically heated platinum wire
for illumination.
In 1887, he modified Edison`s light
bulb and created the first electrical
light bulb for use during urological
procedures.
Original carbonfilament bulbThomas Edison
5. History of Laparoscopy
1901: George Kelling, Dresden,
Saxony (Germany) performed the
1st experimental laparoscopy,
calling it ‘Celioscopy’.
Kelling insufflated the abdomen of
a dog with filtered air and used a
Nitze cystoscope to look inside.
6. Hans Christian Jacobaeus
(1879 – 1937)
1910: Swedish internist; first
thoracoscopic diagnosis with a
cystoscope in a human subject.
Treatment of a patient with tubercular
intra-thoracic adhesions.
The Possibilities for Performing Cystoscopy in
Examinations of Serous Cavities. Münchner Medizinischen
Wochenschrift, 1911
7. Bertram Bernheim
1911 : First laparoscopy at Johns
Hopkins
12mm proctoscope into epigastric incision
on one of Halstead’s patients to stage
pancreatic cancer
Bernheim called his procedure
‘organoscopy’
Findings confirmed on laparotomy
8. History of Laparoscopy
1920: Zollikofer discovered the benefit of CO2 gas for insufflation
1938: Janos Veress developed a spring loaded needle for the
induction of pneumoperitoneum.
After World War II, the development of fiberoptics represented an
important step forward for endoscopy
1966: Hopkins rod lens scope & cold light
1974: Dr Harrith M Hasson, MD working in Chicago, proposed a blunt
mini-laparotomy which permitted direct visualization of the trocar
entrance into the peritoneal cavity. It is popularly known today as
Hasson‘s technique.
9. Kurt Semm (1927-2003)
Once, while making a slide
German Engineer and Gynecologist.
Introduced automatic insufflator,
thermocoagulation ,loop knots,
irrigation device in 1983, performed
endoscopic appendectomy as part of
A gynecologic procedure.
presentation on ovarian cysts;
suddenly the projector was
unplugged - with the
explanation that “such
unethical surgery should not
be presented”
In 1970, after becoming the
chairman of Ob/Gyn at the
University of Kiel, his co-workers
demanded that he undergo a
brain scan because, they said,
“only a person with brain damage
would perform laparoscopic
surgery”
10. History of Laparoscopy
1985: Dr. Muhe (Prof Dr Med - Böblingen, Germany) performed
the first successful laparoscopic cholecystectomy in a human.
However, this was not well publicized until years later. The
German Surgical Society rejected Mühe in 1986 after he reported
that he had performed the first laparoscopic cholecystectomy.
11. Laparoscopy Takes Off
1988: 1st Lap cholecystectomy in the USA, Surgiport 1st
available
1989: US TV picks up on “Key Hole” surgery EndoClip™
released
1990: Cuschieri (Aberdeen) warns on the explosion of
endoscopy
1991: ‘Lap Chole’ is accepted and routine procedure
1992: The National Institutes of Health Consensus
Conference concludes that laparoscopic cholecystectomy is
now the preferred alternative to open cholecystectomy
12. Definition
Minimal access surgery is a marriage of
modern technology and surgical
innovation that aims to accomplish
surgical therapeutic goals with minimal
somatic and psychological trauma
13. Extent of minimal access surgery
Laparoscopy
Thoracoscopy
Endoluminal endoscopy
Perivisiceral endoscopy
Arthroscopy and intra-articular joint surgery
Combined approach
14. What operations can we do
Laparoscopically
Diagnosis
Operation
Gallstone
Cholecystectomy
Appendicitis
Appendicectomy
Hernia
Hernia repair
Adhesions
Division of adhesions
Perforated ulcer
Closure of perforation
Hiatus Hernia
Hiatus hernia repair.
15. What operations can we do
Laparoscopically
Diagnosis
Operation
Colorectal carcinoma
Anterior resection/ APR
Caecal carcinoma
Right Hemicolectomy
Colonic carcinoma
Left/Sigmoid Colectomy
Gastric carcinoma
Gastrectomy
Oesophageal
carcinoma
Oesophagogastrectomy
The list is endless!!!
16. What operations can we do
laparoscopically?
Diagnosis
Operation
Crohn’s Disease
Bowel resection
Diverticulitis
Bowel resection
Rectal Prolapse
Repair of Prolapse
Benign renal disease
Nephrectomy
Gastric Obstruction
Bypass
Some Splenic disorders
Spleenectomy
17. Principle Differences between
Laparoscopic and Open Surgery
FOR THE PATIENT
Post operative pain related to size of incisionsmaller incisions =less pain.
Less Handling of intestines results in little or no
disturbance of normal function.
Avoidance of the trauma of abdominal wall injury
by the incision allows rapid return to normal
activity
No incision allows early return to more strenuous
activities: driving, lifting, sport etc.
18. Principle Differences between
laparoscopic and open surgery
FOR THE HOSPITAL
Initial capital costs to establish laparoscopic surgery in
the order of Rs 10 - 20 lacs
Reduced overall costs by shortening of hospital stay e.g.
cholecystectomy reduced from 5 to 1 day, hiatus hernia
repair reduced from 7 to 3 days.
19. Principle Differences between
laparoscopic and open surgery
For the Surgeon
Magnified view often better than obtained via an
incision allows precise dissection.
Altered (but not absent) tactile response
Two dimensional (flat screen) view.
Usually (but not always) longer operating time
Need to develop entirely different operating
technique
Adaptation of principles of open surgery to
laparoscopic surgery.
20. Instruments
Redesign of instruments for laparoscopic use.
Instruments for open surgery in general 6 – 10” in length
built around a box joint.
Laparoscopic instruments in general 15 – 18” in length
with an articulated connecting rod between handles and
scissor blades, jaws etc.
21. Equipment Necessary for MAS
Camera
Light Source
Insufflator
TV Monitor
Telescopes
Light Guide Cable
Apart from the
insufflator the system
will work better if all
the components are
from the same
company as one
piece talks to another
22. CAMERA
These can be single chip or 3 chip.
CHIP: thois is also called a charged coupled
device in short, CCD.
These are flat silicone wafers with a matrix, a
grid of minute image sensors called pixels.
White balance and sometimes black balance
Sleeve it don’t soak it!!!
23. Light Source
Halogen or Xenon, cold light but beware can still
burn holes in drapes esp. disposable and burn
patient’s skin if left on the abdomen.
Brightest to darkest measured in units of
decibels.
Automatic illumination, does it talk to the camera
and are the necessary leads plugged in.
Lamp life meter, look at it. Is it nearly out? EBME
keep the spares and they change it.
White balance by making sure white is correct
then all the colours through the spectrum are
correct.
24. Insufflator
CO2 because this has the same refractive
index as air, so doesn’t distort the image and
is non combustible.
Intraabdominal pressure run between 10 and
13 mmhg.
Use disposable filter and tubing for each
patient.
High flow insufflators (35 litres) output
determined by size of outlet.
Ensure you know how to change a cylinder
and were they are stored.
25. TV Monitors
Usually a 20” screen.
HD is better.
You can use a standard TV but it must be run
through an isolated transformer.
Horizontal resolution is the number of vertical
lines.
Vertical resolution is the number of horizontal
lines
More lines of resolution, better detail of picture.
26. Telescopes
Come in varying sizes, laparoscopes usually
5mm or 10mm.
Diagnostic 3mm scope available.
Made up of a rod and lens system.
Bundles of fibres, incoherent carry light and
coherent carry image.
Wide range of angles available 0, 30, 45 degree
are fairly standard.
All laparoscopes are autoclavable and can go
through sterilisation, no ultrasonic bath required.
Endo- chameleon- extra long for Bariatric
patients.
27. Light guide Cables
Different diameters
Fibre light cable
Buy auroclavable
Don’t bend to acutely as will break fibres.
Check when you plug them in are all the fibres are okay.
Condensers
28. Instrumentation
SINGLE USE: breaking the Law if you reuse it
on another patient.
Reusable take apart.
Need an ultrasonic washer to effectively clean
them, not for telescopes.
Don’t put 5mm cannulated instruments into a
bench top autoclave that does not have a
vacuum: vacuum is required to remove all air
form lumen of instrument.
Ports 5 and 10mm are the most common, make
sure the right trocar is in port and is it sharp.
29. Electrosurgery
You should be aware of the following
potential situations:
Insulation failure of the active electrode.
Direct coupling of current to other instrumentation
by direct contact.
Capacitance which may be created by two electrical
conductors separated by an insulator
30. Ultrascision or the Harmonic Scalpel
Electrical generator (the box)
This adjusts the amount of electrical energy
being delivered and monitors performance.
Transducer
This is where electrical energy is converted to
the ultrasonic waves. The frequency is fixed
however the amplitude alters with the power
input. the transducer is located in the hand
piece and is connected to the generator by an
electrical cable.
Dissection Instrument (peripheral hand piece)
A metallic rod is coupled to the transducer and
vibrates at the prescribed frequency (i.e.
55kHz). The tip of the rod contacts with the
surface tissue.
31. Principles of Piezo Electronics
The ultrasound waves are created by electrical
energy hitting a negatively charged crystal that
vibrates (expands and contracts) at a particular
frequency. These crystals are disc shaped and
made of ferroelectric ceramics. A pair of discs
“coupled” together produce a sinusoidal wave
form. This coupling results in a harmonic
waveform that is of high electroacoustic
efficiency.
32. VERESS NEEDLE
1938 - Janos Veress, of Hungary, developed the springloaded needle. to perform therapeutic pneumothorax
(TB).
Made of surgical stainless steel with a single trap valve.
2mm diameter x 80mm length
It consists of an outer cannula with a bevelled needle
point for cutting through tissues.
33. GAS INSUFFLATION
Controlled pressure insufflation of the peritoneal cavity
is used to achieve the necessary work space for
laparoscopic surgery.
Automatic insufflators allow the surgeon to preset the
insufflating pressure, and the device supplies gas until
the required intra-abdominal pressure is reached.
34. Trocar
The trocar has a blade with
a shaft and body.
The body includes a
pointed tip which makes
the initial incision in the
abdominal wall of the
patient.
(Trocar diameters range from
2mm-30 mm)
36. Telescope
There are three important
structural differences in
telescope available
1. 6 to 18 rod lens system
telescopes are available
2. 0 to 120 degree telescopes
are available
3. 1.5 mm to 15 mm of
telescopes are available
37. Optic cables
These cables are
made up of a bundle of
optical fibers glass
thread swaged at both
ends.
The fiber size used is
usually between 10 to
25 mm in diameter.
They have a very high
quality of optical
transmission, but are
fragile.
38. Dissecting & Grasping Forceps
Atraumatic
KELLY atraumatic
Atraumatic, with hollow jaws
MANGESHKAR Grasping
Forceps, serrated
39. General instruments
Reusable three-piece design
Available in 2 mm, 3 mm,
3.5mm, 5 mm and 10 mm
sizes, with lengths of 20 cm,
30 cm, 36 cm and 43 cm.
Choice of handle styles.
Fully rotating 360° sheath.
No hidden spaces that can
trap operative blood and
tissue debris.
40. Scissors
HOOK SCISSORS, single action
jaws
METZENBAUM SCISSORS,
curved, length of blades 12-17 mm,
widely used as an instrument for
mechanical dissection in
laparoscopic surgery.
STRAIGHT SCISSOR can give
controlled depth of cutting because
it has only one moving jaw.
43. Correct trocar placement should provide
direct access to the target organs,
an optimal view of the operative field
and minimize mental and muscular fatigue.
44. tro-car [Fr., troisis, three +carre, side] noun
a sharp-pointed surgical instrument
fitted with a cannula and used
especially to insert the cannula into
a body cavity
cannula - [L., dim of
canna,reed] noun
a tube that is inserted into a cavity
by means of a trocar filling it’s lumen
45. Avoid competing
for the same space:
“Dueling
swords”
phenomenon
(scissoring effect)
Working against the camera
and ‘blind spots’
47. Avoid the epigastric vessels
Saber et al. Safety zones for anterior abdominal wall entry during laparoscopy. Ann
Surg 2004; 239:182
48. Anatomic distribution of nerves across
anterior abdominal wall
Ilioinguinal nerve
Iliohypogastric nerve
(adapted from) Anatomy of ilioinguinal and iliohypogastric nerves in relation to trocar placement and low transverse
incisions James L. Whiteside, MD, Matthew D. Barber, MD, MHS, Mark D. Walters, MD, and Tommaso Falcone, MD
(Am J Obstet Gynecol 2003;189:1574-8.)
49. Incision line/trocar sites vs. nerve distribution
Epigastric a.
Iliohypogastric n.
Ilioinguinal n.
Trocar site
Pfannenstiel incision
(adapted from) Anatomy of ilioinguinal and iliohypogastric nerves in relation to trocar placement and
low transverse incisions James L. Whiteside, MD, Matthew D. Barber, MD, MHS, Mark D. Walters, MD, and
Tommaso Falcone, MD (Am J Obstet Gynecol 2003;189:1574-8.)
50. Be aware of bladder location
for suprapubic trocar
52. Additional
trocars can be
added along the
semicircular line.
Trocar distance from the
target organ depends upon
the size of the patient.
Individual trocars can be
moved closer to the target
along an axis line.
53. Gold Standard Laparoscopic Procedures
Today
Laparoscopic cholecystectomy
Laparoscopic RYGB for obesity
Laparoscopic adrenalectomy
Laparoscopic splenectomy
56. LAP-BAND
Trocars - placed high, close
to
the costal margin.
Trocar A - liver retraction.
Trocar D - can be enlarged to
allow for placement of a port.
Trocar C - placed left of the
midline for correct view of
Angle of His.
A
B
E
C
D
57. Laparoscopic RYGB
Multicenter, prospective, risk-adjusted
data show that laparoscopic gastric
bypass is safer than open gastric
bypass, with respect to 30-day
complication rate.
LRYGB has become the standard of
care
Hutter et al. Ann Surg. May 2006
Massachusetts General Hospital, Boston.
60. Laparoscopic adrenalectomy
Less blood loss
Less operative time!!
Less hospital stay
Less post operative pain
Tiberio et al.
Prospective RCT
Surg Endosc. Jun 2008
61. Indications for Adrenalectomy
Unilateral adrenalectomy
Bilateral adrenalectomy
Hyperfunctioning tumors
Aldosteronoma
Cortisol-producing adenoma
Virilizing tumors
Pheochromocytoma
Nonfunctioning cortical adenomaa
Failed treatment of ACTH-dependent
Cushing’s syndrome
Cushing’s syndrome from primary
adrenal hyperplasia
Malignant tumors
Adrenocortical carcinoma
Malignant pheochromocytoma
Adrenal metastasis (solitary without
other metastatic
disease)
symptomatic or enlarging adrenal
myelolipomas, ganglioneuroma
ACTH: adrenocorticotrophic hormone
Bilateral pheochromocytoma
67. Hernia - Historic Perspective
Galen of Pergamum (AC 129-179) who was a
surgeon to the gladiators practiced ligation of the sac
and cord with amputation of the testicle.
Guy de Chauliac (AC 1300-1368) in his book
Chirurgia Magna: laxatives, hang patient from his
legs, bed rest for 50 days.
71. What are indications for laparoscopic
inguinal hernia repair?
Recurrent hernia
• Avoids scar tissue
• Visualizes occult hernia
Bilateral hernia
• Decreased pain
• Earlier return to work
• No difference in recurrence or complication
Obese / Athletic patients
• Definitive diagnosis
• Reduced infection in susceptible population
• Gilmore’s groin
Patients with contralateral injury to vas deferens
• Less chance to injure other vas
72. Are there contraindications to
lap. inguinal hernia repair?
Contraindications
• Patients for whom general anesthesia and
pneumoperitoneum are risks (cardiac, pulmonary
disease)
Relative Contraindications
• Prior pre-peritoneal surgery (prostate, hernia, vascular,
kidney transplant)
• Prior laparotomy
• Ascites
• Strangulated hernia
• Giant scrotal hernia
• Anticipated bleeding (patients on anti-coagulation)
73. 2. Do we have an answer for
groin pain after hernia repair?
86. APPENDECTOMY
Alternatively, an appendectomy can be performed through a
trocar in the umbilicus and two trocars in the suprapubic area
medial to the epigastric vessels for a superb cosmetic result (if
an extended right hemicolectomy is to be performed, the
hepatic flexure positioning is preferred.)
87. Laparoscopic Appendectomy
Evidence-based Medicine
Clear advantage in children*
- Less wound infection, LOS, ileus
- More OR time, intra-abdominal abscess
Controversies in adults
- Cost, obese patients, severe appendicitis
- Prelude to NOTES
*Aziz et al. Ann Surg 2006
90. Anti-reflux surgery
1945 to present
Multiple methods and techniques:
Nissen fundoplication
Dor wrap
Hill gastropexy ….
Different approaches:
Laparotomy vs laparoscopy
Thoracotomy vs thoracoscopy
Rudolph Nissen, MD
INFLUENTIAL PEOPLE:
Lortat-Jacob, MD
AndreToupet, MD
Jacques Dor, MD
Ernst Heller, MD
Rudolph Nissen MD
Ivor Lewis, MD
J. Leigh Collis, MD
K. Alvin Merendino, MD
Lucius Hill, MD
Ronald Belsey, MD
Alan Thal, MD
96. • Do not use metal tacks
• Biologic mesh? dual mesh?
Esophagus
• No mesh at all?
(remember original Toupet repair)
Polypropylene mesh
Mesh
Circular mesh
Wrap
Fundoplication
99. NOTE:
If proximal divided end of colon can reach
through
the skin there has been sufficient dissection of
splenic flexure providing a tension-free
anastomosis.
100. HEPATIC FLEXURE
COLON
RESECTION
C
Tension-free anastomosis
B
A
Trocar C is used for GIA division
of distal ileum and midtransverse
colon (site is enlarged to retrieve
specimen and for extracorporeal
anastomosis).
The ileum is more mobile than the
transverse colon, which can still be
delivered adequately at this level.
103. Laparoscopic colorectal surgery
Cochrane Systematic review of short term outcomes in 25 RCTs showed that
laparoscopic colorectal surgery had:
Longer operative time
Less intraoperative blood loss
Less postoperative pain
less postoperative ileus
Better postoperative pulmonary function
Less total and local morbidity
Less postoperative hospital stay
Similar general morbidity and mortality
Better quality of life (within 30 days)
Schwenk et al. 2005 Jul 20;(3):Cochrane Database 003145
Cochrane Systematic review of long term outcomes showed:
Similar port-site metastases and wound recurrences
Similar cancer-related mortality at maximum follow-up
Similar tumor recurrence
Similar overall mortality
Kuhry et al. Cancer Treat Rev. Oct 2008
104. Laparoscopic hepatectomy
First performed 1994
by Huscher et al
A safe procedure in
experienced hands
Resection devices:
Staplers
Bipolar vessel sealing
(Ligasure)
Radiofrequency
U/S dissector
Nd-YAG laser
Laparoscopic left hemihepatectomy (resection of
segments 2, 3, and 4). (A) Intraoperative view
showing ischemic delineation of the left liver.
Note the vascular endoscopic stapler encircling
the left Glissonian pedicle. (B) Schematic view.
The stapler is closed, and ischemic delineation
of the left liver is obtained. (C) Intraoperative
view. The stapler is fired, and the left main
Glissonian pedicle is transected (arrows). (D)
Schematic view. The stapler is fired
105. Laparoscopic pancreatectomy
Pancreaticoduodenectomy
Total splenopancreatectomy
Spleen-preserving total
pancreatectomy
Distal splenopancreatectomy
Spleen-preserving distal
pancreatectomy
Central pancreatectomy
Enucleation
Procedures are technically
challenging
Long learning curve
High volume center improves
clinical outcome
107. Laparoscopic pancreatectomy Vs. open
Finan et al. Am Surg. Aug 2009
Laparoscopic and open distal
pancreatectomy: a comparison of
outcomes.
There was no significant difference in the
incidence of postoperative morbidity or
mortality
There was no significant difference in the rate
of all pancreatic fistula formation or clinically
significant leaks
Lparoscopic technique had decreased:
operative time
blood loss
length of stay in the lap group.
Conclusion
Lap and open distal pancreatectomy are
performed safely at high-volume
pancreatic surgery centers.
109. RT. KIDNEY RESECTION
• Subxiphoid port (D) - liver retraction
Trocar A - parallel to vena cava
(perpendicular approach to rt. renal
vessels and rt. adrenal vein –
additional trocar E may be placed
more laterally and posterior to
trocar A if needed.)
•
D
C
E
A
B
110. PROSTATECTOMY
Trocars – added as needed along semicircular
line. i.e., during a prostatectomy, another
trocar is added between A and B.
Another trocar may be added between B and
C allowing the surgeon and assistant surgeon
on the opposite side to each use both hands.
A
B
C
114. Conclusions
MIVAT and MIVAP yield equivalent endocrine results
as open procedure
Oncologic result is equivalent in selected patients
Equivalent safety profile as open procedures
Postop pain is decreased
Patient satisfaction with procedure and cosmetic
result is significantly increased
(Miccoli et al., RCT, Surgery. 2001)
Yet:
What about large masses?!
116. History of Robotics
Leonardo da Vinci
developed one of the
first robots in 1495 – an
armored knight for the
purposes of
entertaining royalty.
117. What Robotics Aimed to Improve in Laparoscopy
Surgeon operates from a 2D
image
Straight, rigid instruments
(limited range of motion)
Instrument tips controlled at a
distance
Reduced dexterity, precision &
control
Unsteady camera controlled by
assistant
118. Surgical Robots
AESOP (Automated Endoscopic System for Optimal
Positioning)
- Voice activated mechanical arm
- Steadier than human, never tires
da Vinci®
- FDA approval in 2002
- Laparoscopic instrumentation controlled by the
surgeon, positioned remotely at a console
119. Development of da Vinci®
Defense Advanced Research Projects Agency (DARPA)
for military research of remote battlefield surgery
Cholecystectomy performed remotely via telesurgery from 300 miles
away
Intuitive surgical created in 1999 after acquiring patent rights from
military
First robotic prostatectomy performed in 2001
120. What is the da Vinci® Surgical System?
State-of-the-art robotic
technology
Surgeon in control
Assistant has direct access
121. What is the da Vinci®
Surgical System?
Surgeon directs precise
movements of instruments in
the slave unit using console
controls.
123. Wrist and Finger Movement
Laparoscopic instruments
are rigid with no wrists
EndoWrist® Instrument tips
move like a human wrist
Allows surgeon to operate
with increased dexterity &
precision. No tremor
124. Disadvantages of da Vinci® Robot
Expensive
- $1.4 million cost for machine
- $120,000 annual maintenance contract
- Disposable instruments $2000/case
Steep surgical learning curve
Loss of tactile feedback
Increased staff training/competence
Increased OR set-up/turnover time!!
127. What does that stand for ?
SILS – Single Incision Laparoscopic Surgery
SSA – Single Site Access
SPA – Single Port Access
SAS – Single Access Site
SPL – Single Port Laparoscopy
LESS – Laparo Endoscopic Single Site Surgery
TUES – Trans Umbilical Endoscopic Surgery
135. A Recent History of
“New Minimal Access” Surgery
2000 Flexible endoscopic endoluminal therapy for GERD
2003 Kalloo et al transgastric peritoneoscopy with flexible
endoscope
2004 Rao and Reddy reported on transgastric
cholecystectomy and appendectomy in patients
2006 summit meeting: NOSCAR (Natural Orifice Surgery
Consortium for Assessment and Research) formed
136. Alleged NOTES Benefits
No surface incision
Reduced surgical site infection
Reduced visible scarring
Reduction in pain analgesics
Quicker recovery time
Reduction in hernias, adhesions
Advantages in the morbidly obese
144. Diabetes
Considered major public health problem – emerging as a world
wide pandemic. In 1995 ~ 135 million people worldwide
Currently 240 million, expected to rise to close to 380 million by
2025
Complications
Peripheral vascular disease (PVD) accounts for 20-30%
10% of cerebral vascular accident
Cardiovascular disease accounts for 50% of total mortality
1. Venkat et al Diabetes–a common, growing, serious, costly, and potentially preventable public health problem. Diabetes Res
Clin Pract. 2000; 5 (Suppl2): S77–S784.
2. H. King et Global burden of diabetes, 1995-2025: prevalence, numerical estimates and projections. Diabetes Care 21 (1998)
1414-1431.
3. Annals of Surgery. Volume 251, Number 3, March 2010
147. Long-term Weight Control Analysis
Studies
Type and Size
Effect on Weight
Effect on Comorbidities
Resolution of:
Buchwald et al.
Meta-analysis
n = 22,094 pts
Mean excess
weight loss: 61%
n
Swedish Obese
Subject trial (SOS)
Prospective matched
cohort
n = 4,047 pts
At 10 years:
Med: 1.6% gain
Surg: 16% loss
Diabetes: 70%
HTN: 62%
Sleep apnea: 86%
Improved by surgery:
Diabetes
Lipid profile
HTN
Hyperuricemia
1. Buchwald H, Avidor Y, Braunwald E, Jensen MD, Pories W, Fahrbach K, et al. Bariatric surgery: a systematic review
and meta-analysis. JAMA 2004; 292: 1724-37.
2. Sjostrom L, Lindros AK, Peltonem M, Torgerson J, Bouchard C, Carlsson B, et al. Lifestyle, diabetes, and
cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med 2004; 351: 2683-93.
148. Schauer et al.
Effect of laparoscopic Roux-en Y gastric bypass on
type 2 diabetes mellitus.
Ann Surg. 2003 Oct; 238 (4): 467-84
1160 patients underwent LRYGBP 5-year
period
LRYGBP resulted in significant weight loss
(60% percent of excess body weight loss) and
resolution (83%) of T2DM
Fasting plasma glucose and HBA1C normalized
(83%) or markedly improved (17%) in all patients
Patients with the shortest duration and mildest
form of T2DM had a higher rate of T2DM
resolution after surgery
suggesting that early surgical intervention
is warranted to increase the likelihood of
rendering patients euglycemic
149. Rates of Remission of Diabetes
Adjustable
Gastric Banding
Roux-en-Y
Gastric Bypass
Biliopancreatic
Diversion
48%
84%
>95%
(Slow)
(Immediate)
(Immediate)
150. 2002: Antidiabetic Effect of
Bariatric Surgery: Direct or Indirect?
“Gastric bypass and biliopancreatic diversion
seem to achieve control of diabetes as a primary and
independent effect, not secondary
to the treatment of overweight.”
Potential of Surgery for Curing Type 2 Diabetes Mellitus. Rubino, Francesco, MD; Gagner,
Michel MD, FACS, FRCSC Annals of Surgery; 236 (5): 554-559, November 2002
151. 2004:
“Results of our study support the hypothesis
that the bypass of duodenum and jejunum can
directly control type 2 diabetes and
not secondarily to weight loss or treatment of obesity.”
Effect of Duodenal-Jejunal Exclusion in a Non-obese Animal Model of Type 2 Diabetes: A
New Perspective for an Old Disease. Rubino, Francesco, MD; Marescaux, Jacques MD,
FRCS Annals of Surgery; 239 (1): 1-11, January 2004
153. THE FUTURE
It has not changed the nature of disease
The basic principles of good surgery still
apply,including appropriate case selection, excellent
exposure,adequate retraction and a high level
technical expertise
If a procedure makes no sense with conventional
access, it will make no sense with a minimal access
approach
154. THE FUTURE
The cleaner and gentler the act of
operation, the less the patient
suffers, the smoother and quicker
his convalescence,the more
exquisite his healed wound.
Berkeley George Andrew Moynihan
Despite these advantages, there are still many drawbacks to a conventional laparoscopy.
The surgeon operates looking at a monitor that only shows a two dimensional image.
The rigid instruments the surgeon works with are controlled from a distance; they have no wrists, which decreases precision, dexterity and control.
As a result, the surgeon will also tire more quickly.
Due to the small incision, the participation of the assistant is limited. This makes complex gynecologic operations very difficult, resulting in a higher likelihood that you will receive larger incision.
The da Vinci System was designed to overcome the limitations of the traditional open and conventional laparoscopic (minimally invasive) approaches.
da Vinci is a state-of-the-art surgical robotic system that provides the extended capabilities necessary to complete your procedure using only a few small incisions.
With da Vinci Surgery, the surgeon is seated at a nearby console and always in full control of the robotic instruments.
Since the assistant is next to the patient and has direct access to the surgical site, he or she can assist during complex steps of the procedure.
Using master controls the System directly translates the surgeon’s hand movements into precise micro-movements of the instrument tips.
Specialized instruments increase dexterity, and help the surgeon to perform a more precise surgery.
The da Vinci System cannot be programmed to act on its own, and therefore requires the continuous, direct input of your surgeon.
If you remember from before, conventional minimally invasive instruments are rigid and have no wrists.
The EndoWrist instruments of the da Vinci System move like a human wrist.
This allows the surgeon to control the instruments with the precision necessary to perform complex procedures like lymph node dissection using only a few tiny incisions.