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International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 07 Issue: 03 | Mar 2020 www.irjet.net p-ISSN: 2395-0072
© 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 5278
AUTOMATED 3-D SEGMENTATION OF LUNG WITH LUNG CANCER IN CT
DATA USING A NOVEL ROBUST ACTIVE SHAPE MODEL APPROACH
Vaijayanthimala J, Lakkshaya JS, Kanimozhi M, Aswini S, Haridharani S
1 Assistant Professor, Department of Computer Science and Engineering, Dhirajlal Gandhi College of Technology,
Tamilnadu, India
2,3,4,5Final Year Student , Department of Computer Science and Engineering, Dhirajlal Gandhi College of
Technology, Tamilnadu, India
--------------------------------------------------------------------***-----------------------------------------------------------------------
Abstract - Segmentation of lungs with (large) lung cancer
regions could be a nontrivial problem. Our method consists
of two main processing steps. First, a novel robust active
shape model (RASM) matching method Applied to roughly
segment the outline of the lungs. The initial position of the
RASM is found by means of a skeletal structure detection
method. Second, an optimal surface finding approach is
employed to further adapt the initial segmentation result to
the lung. Experiments on the identical 30 data sets showed
that our methods delivered statistically significant better
segmentation results, compared to 2 commerciallyavailable
lung segmentation approaches. Additionally, our RASM
approach is mostly applicable and suitable for big shape
models.
KeyWords: lung cancer, lung segmentation, computed
tomography, active shape model, lung nodules.
1. INTRODUCTION
Lung cancer could be a major reason behind cancer-related
deaths; it can be detected early by detecting the lung
nodules. The main idea of this project is to detect lung
nodule and to classify nodules as cancerous and non-
cancerous using Genetic Programming-based Classifier
(GPC) technique. Thus the lung CT image is subjected to
varied processing steps and features are extracted for a
collection of images. The processing steps include
thresholding, morphological operationsandhaveextraction.
By using these stepsthenodulesaredetectedandsegmented
and a few features are extracted. The extracted features are
tabulated for future classification.
The x-ray computerized axial tomography (CT) provides a
2D transaxial sectional map of the linear attenuation
coefficient mirroring morphological details of the organs
under study. Because it is mostly recognized, X-ray CT could
be a high spatial resolution and wide dynamic rangeimaging
modality, where, even rather small meaningful density
abnormalities are often detected. Contour extraction often
occurs as a pre-processing step of a more global image
analysis task. It happens to be the case of computer aided
analysis of pulmonary X-ray tomograms 1 where many
analysis algorithms start by correctly identifying eachone of
the pulmonary regions. With modern spiral CT machines
lung imaging is usually performed athighresolutionsettings
both at the sectional and longitudinal levels. The overall
result's an ever-growing volume of data justifying the
development of more efficient and accurate segmentation
procedures.Fastsegmentationproceduresalsoaredefinitely
important for 3D visualization purposes where a batch of
slices may need to be prepared for surface or volume
rendering. During this work, we present a completely
automated and fast method, which is ready to perform
pulmonary contour extraction and region identification.
2. EXISTING SYSTEM
The robotic quantification of lung disease requires the
segmentation of lung parenchyma inanearlygivingoutstep.
Normal lungs imaged with CT, a large thickness difference
between air-filledlungparenchyma and surroundingtissues.
To enable computer-aided cancer treatment preparation
(e.g., surgery or radiation treatment) and to make easy the
quantitative review of lung cancer loads, robust lung
segmentation methods are required. The segmentation of
lungs with large cancer area atabilitylocations.Forexample,
a Bezier surface-based method was proposed in to deal with
injury adjacent to the chest wall and mediastinum. “Break-
and-Repair” strategy which was use to segment lungs with
juxtapleural lung nodules. A new approach for the fully
automated segmentation of lungs with lung cancer regions
which addresses the limitations of existing methods like
robustness or processing speed.we provide a performance
comparison withtwocommerciallyavailablemethodsonthe
same image data. Both methods are used routinely in the
context of lung radiation Treatment planning. Approach
addresses this issue the vigorous matching algorithm is
specifically designed to take advantage of general-purpose
computation ongraphicsprocessingunits,whichreduces the
execution time considerably.
2.1 Drawbacks
 Limitation robustness or processing speed.
 The lung shape is encountered cannot be explained
by using model.
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 07 Issue: 03 | Mar 2020 www.irjet.net p-ISSN: 2395-0072
© 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 5279
 Mostly target population is depending upon the
missing data.
 A more dense mesh vertex in combination with an
adaption of search profiles is required
3. PROPOSED SYSTEM
Our robust model matching method successfully deals with
outliers and other disturbances. The optimal surfacefinding
step after robust ASM segmentation reducesthe necessityto
feature new lung shapes to the learning set. Pneumothorax
or pleural effusion is difficult to segment automatically, and
our model-based approach might require some additional
processing steps. Performance may be further improved by
utilizing more complex cost functions for model matching
and optimal surface finding, which might be supported the
relative location of shape points moreover as density/gray-
value properties and shape features. The detected ribs are
only utilized for model initialization, but can provide
valuable information for cost function design. Theproposed
work targets larger cancer masses and is not optimized for
handling junta pleural nodules. Left and right lungs are
segmented separately, which might cause inconsistencies.
We have utilized a straightforward cost function supported
gradient magnitude and direction. The performance may be
further improved by utilizing more complex cost functions
for model matching and optimal surfacefindingwhichmight
be supported the relative location of shape points moreover
as density/gray-value properties and shape features.
3.1 Advantages
 Processing time get raise.
 Parallel processing.
 Only one model needs to be matched to
volumetric image data instead of several data
sets
 Reduces the execution time
4. IMPLEMENTATION
The implementation contains collection of CT images and
processing the images by novel robust active shape model
(RASM) approach. The implementation of project includes
RIB detection and ASM matching for optimal surfacefinding.
The noise and other highrecurrencesegmentsareevacuated
by filters and prepare the datasets for additional processing.
It is an optimal filters and has the ability of dealing with
noise. The following System is the procedure for process the
information.
Fig-4(a) Dataflow diagram
5. MODULE DESCRIPTION
5.1 Processing of an image
Processing an image is to enhance the image quality.
Preprocessing is the method ofincludesmoothing,sampling,
and filtering. In this method we are going to do reduce the
noises by using filters. Filtering is used to remove the
unwanted noises in an image. A common image processing
task is to apply an image processing algorithm to a series of
files. This procedure can be time consuming if the algorithm
is computationally intensive, if you are processing a large
number of files, or if the files are very large. This demo
shows how to batch process a set of image files in parallel.
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 07 Issue: 03 | Mar 2020 www.irjet.net p-ISSN: 2395-0072
© 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 5280
Fig-5(a) Input image Fig-5(b) preprocessing
Image
5.2 Model Intialization
The model initialization method which is based on a novel
rib detection approach that is suitablefornormal orcontrast
enhanced CT scans. Initial shapeandpose(size,rotation, and
location) parameters of theASMneedto bedetermined.Here
in this module we are going to segment the lung cancer
image by region segmentation process. Image segmentation
is typically used to locate objects and boundaries (lines,
curves, etc.) in images. More precisely, image segmentation
is the process of assigning a label to every pixel in an image
such that pixels with the same label share certain visual
characteristics. Threshold methodisusedtosegmentthe left
and right lungs.
Fig - 5(c) Model Initialization
5.3 optimal Surface Finding
The PDM (point distribution model) can be used for lung
segmentation by matching the model to the target structure.
It has a standard ASM matching framework. An instance of
the shape model is generated and placed in proximity to the
target structure. Thealgorithmtransformsthesegmentation
problem into a graph optimization problem, which is solved
by means of a maximum-flow algorithm. Hereinthismodule
we add the noise to the original image and we remove
through denoising process is made through approximation
algorithm. After the edge surfaces in the neighborhood are
approximated by a surface template, the neighborhood is
divided by the surface template into sub neighborhoods.
Fig-5(d) Optimal Surface Finding
6. CONCLUSIONS
The fully automated segmentation of lungs with Lung
cancer regions was presented. The robustness and
effectiveness of our advance was demonstrated on 30 lung
scans containing 20 normal lungs and 40 diseased. Lungs
where usual segmentation methods frequentlyfail todeliver
usable results. Low segmentation errors were achieved in
cases with and without high-density pathology,compared to
two clinically utilized methods. The presented approach to
lung segmentation exposesnewavenuesforcomputer-aided
lung image analysis. A core component of our method may
be a novel robust ASM matching method. The approach not
only allows addressing disturbances but it is also well
suitable for large shape modelsandparallel implementation,
allowing low computationtimes.OurrobustASMframework
is additionally applicable to other segmentation problems
furthermore as imaging modalities, requiring mainly an
adaption of the matching cost function.
REFERENCES
[1] S. G. Armato and W. F. Sensakovic, “Automated lung
segmentation for thoracic CT,” Acad. Radiol., vol. 11, no. 9,
pp. 1011–1021, 2004.
[2] J. K. Leader, B. Zheng, R. M. Rogers, F. C. Sciurba, A. Perez,
B. E. Chapman, S. Patel, C. R. Fuhrman, and D. Gur,
“Automated lung segmentation in X-ray computed
tomography,” Acad. Radiol., vol. 10, no. 11, pp. 1224–1236,
2003.
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 07 Issue: 03 | Mar 2020 www.irjet.net p-ISSN: 2395-0072
© 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 5281
[3] A. Silva, J. S. Silva, B. S. Santos, and C. Ferreira, “Fast
pulmonary contour extraction in X-ray CT images: A
methodology and quality assessment,” in Proc. SPIE Med.
Imag., 2001, vol. 4321, pp. 216–224.
[4] S. Hu, E. A. Hoffman, and J. M. Reinhardt, “Automatic lung
segmentation for accurate quantitation of volumetric X-ray
CT image,” IEEE Trans. Med. Imag., vol. 20, no. 6, pp. 490–
498, Jun. 2001.
[5] E. A. Hoffman and E. L. Ritman, “Effectofbodyorientation
on regional lung expansion in dogandsloth,” J.Appl.Physiol.,
vol. 59, no. 2, pp. 481–491, 1985.
[6] T. Kitasaka, K. Mori, J. Hasegawa, and J. Toriwaki, “Lung
area extraction from 3-D chest X-ray CT images using a
shape model generated by a variable Bézier surface,” Syst.
Comput. Jpn., vol. 34, no. 4, pp. 60–71, 2003.
[7] J. Pu, J. Roos, C. A.Yi, S. Napel, G. D. Rubin, and D. S. Paik,
“Adaptive border marching algorithm: Automatic lung
segmentation on chest CT images,” Computer. Med. Imag.
Graph., vol. 32, no. 6, pp. 452–462, 2008.
[8] J. Pu, D. S. Paik, X. Meng, J. E. Roos, and G. D. Rubin, “Shape
breakand- repair strategy and its application to automated
medical image segmentation,” IEEE Trans. Vis. Comput.
Graphics, vol. 17, no. 1, pp. 115–124, Jan. 2011.

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  • 1. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 07 Issue: 03 | Mar 2020 www.irjet.net p-ISSN: 2395-0072 © 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 5278 AUTOMATED 3-D SEGMENTATION OF LUNG WITH LUNG CANCER IN CT DATA USING A NOVEL ROBUST ACTIVE SHAPE MODEL APPROACH Vaijayanthimala J, Lakkshaya JS, Kanimozhi M, Aswini S, Haridharani S 1 Assistant Professor, Department of Computer Science and Engineering, Dhirajlal Gandhi College of Technology, Tamilnadu, India 2,3,4,5Final Year Student , Department of Computer Science and Engineering, Dhirajlal Gandhi College of Technology, Tamilnadu, India --------------------------------------------------------------------***----------------------------------------------------------------------- Abstract - Segmentation of lungs with (large) lung cancer regions could be a nontrivial problem. Our method consists of two main processing steps. First, a novel robust active shape model (RASM) matching method Applied to roughly segment the outline of the lungs. The initial position of the RASM is found by means of a skeletal structure detection method. Second, an optimal surface finding approach is employed to further adapt the initial segmentation result to the lung. Experiments on the identical 30 data sets showed that our methods delivered statistically significant better segmentation results, compared to 2 commerciallyavailable lung segmentation approaches. Additionally, our RASM approach is mostly applicable and suitable for big shape models. KeyWords: lung cancer, lung segmentation, computed tomography, active shape model, lung nodules. 1. INTRODUCTION Lung cancer could be a major reason behind cancer-related deaths; it can be detected early by detecting the lung nodules. The main idea of this project is to detect lung nodule and to classify nodules as cancerous and non- cancerous using Genetic Programming-based Classifier (GPC) technique. Thus the lung CT image is subjected to varied processing steps and features are extracted for a collection of images. The processing steps include thresholding, morphological operationsandhaveextraction. By using these stepsthenodulesaredetectedandsegmented and a few features are extracted. The extracted features are tabulated for future classification. The x-ray computerized axial tomography (CT) provides a 2D transaxial sectional map of the linear attenuation coefficient mirroring morphological details of the organs under study. Because it is mostly recognized, X-ray CT could be a high spatial resolution and wide dynamic rangeimaging modality, where, even rather small meaningful density abnormalities are often detected. Contour extraction often occurs as a pre-processing step of a more global image analysis task. It happens to be the case of computer aided analysis of pulmonary X-ray tomograms 1 where many analysis algorithms start by correctly identifying eachone of the pulmonary regions. With modern spiral CT machines lung imaging is usually performed athighresolutionsettings both at the sectional and longitudinal levels. The overall result's an ever-growing volume of data justifying the development of more efficient and accurate segmentation procedures.Fastsegmentationproceduresalsoaredefinitely important for 3D visualization purposes where a batch of slices may need to be prepared for surface or volume rendering. During this work, we present a completely automated and fast method, which is ready to perform pulmonary contour extraction and region identification. 2. EXISTING SYSTEM The robotic quantification of lung disease requires the segmentation of lung parenchyma inanearlygivingoutstep. Normal lungs imaged with CT, a large thickness difference between air-filledlungparenchyma and surroundingtissues. To enable computer-aided cancer treatment preparation (e.g., surgery or radiation treatment) and to make easy the quantitative review of lung cancer loads, robust lung segmentation methods are required. The segmentation of lungs with large cancer area atabilitylocations.Forexample, a Bezier surface-based method was proposed in to deal with injury adjacent to the chest wall and mediastinum. “Break- and-Repair” strategy which was use to segment lungs with juxtapleural lung nodules. A new approach for the fully automated segmentation of lungs with lung cancer regions which addresses the limitations of existing methods like robustness or processing speed.we provide a performance comparison withtwocommerciallyavailablemethodsonthe same image data. Both methods are used routinely in the context of lung radiation Treatment planning. Approach addresses this issue the vigorous matching algorithm is specifically designed to take advantage of general-purpose computation ongraphicsprocessingunits,whichreduces the execution time considerably. 2.1 Drawbacks  Limitation robustness or processing speed.  The lung shape is encountered cannot be explained by using model.
  • 2. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 07 Issue: 03 | Mar 2020 www.irjet.net p-ISSN: 2395-0072 © 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 5279  Mostly target population is depending upon the missing data.  A more dense mesh vertex in combination with an adaption of search profiles is required 3. PROPOSED SYSTEM Our robust model matching method successfully deals with outliers and other disturbances. The optimal surfacefinding step after robust ASM segmentation reducesthe necessityto feature new lung shapes to the learning set. Pneumothorax or pleural effusion is difficult to segment automatically, and our model-based approach might require some additional processing steps. Performance may be further improved by utilizing more complex cost functions for model matching and optimal surface finding, which might be supported the relative location of shape points moreover as density/gray- value properties and shape features. The detected ribs are only utilized for model initialization, but can provide valuable information for cost function design. Theproposed work targets larger cancer masses and is not optimized for handling junta pleural nodules. Left and right lungs are segmented separately, which might cause inconsistencies. We have utilized a straightforward cost function supported gradient magnitude and direction. The performance may be further improved by utilizing more complex cost functions for model matching and optimal surfacefindingwhichmight be supported the relative location of shape points moreover as density/gray-value properties and shape features. 3.1 Advantages  Processing time get raise.  Parallel processing.  Only one model needs to be matched to volumetric image data instead of several data sets  Reduces the execution time 4. IMPLEMENTATION The implementation contains collection of CT images and processing the images by novel robust active shape model (RASM) approach. The implementation of project includes RIB detection and ASM matching for optimal surfacefinding. The noise and other highrecurrencesegmentsareevacuated by filters and prepare the datasets for additional processing. It is an optimal filters and has the ability of dealing with noise. The following System is the procedure for process the information. Fig-4(a) Dataflow diagram 5. MODULE DESCRIPTION 5.1 Processing of an image Processing an image is to enhance the image quality. Preprocessing is the method ofincludesmoothing,sampling, and filtering. In this method we are going to do reduce the noises by using filters. Filtering is used to remove the unwanted noises in an image. A common image processing task is to apply an image processing algorithm to a series of files. This procedure can be time consuming if the algorithm is computationally intensive, if you are processing a large number of files, or if the files are very large. This demo shows how to batch process a set of image files in parallel.
  • 3. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 07 Issue: 03 | Mar 2020 www.irjet.net p-ISSN: 2395-0072 © 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 5280 Fig-5(a) Input image Fig-5(b) preprocessing Image 5.2 Model Intialization The model initialization method which is based on a novel rib detection approach that is suitablefornormal orcontrast enhanced CT scans. Initial shapeandpose(size,rotation, and location) parameters of theASMneedto bedetermined.Here in this module we are going to segment the lung cancer image by region segmentation process. Image segmentation is typically used to locate objects and boundaries (lines, curves, etc.) in images. More precisely, image segmentation is the process of assigning a label to every pixel in an image such that pixels with the same label share certain visual characteristics. Threshold methodisusedtosegmentthe left and right lungs. Fig - 5(c) Model Initialization 5.3 optimal Surface Finding The PDM (point distribution model) can be used for lung segmentation by matching the model to the target structure. It has a standard ASM matching framework. An instance of the shape model is generated and placed in proximity to the target structure. Thealgorithmtransformsthesegmentation problem into a graph optimization problem, which is solved by means of a maximum-flow algorithm. Hereinthismodule we add the noise to the original image and we remove through denoising process is made through approximation algorithm. After the edge surfaces in the neighborhood are approximated by a surface template, the neighborhood is divided by the surface template into sub neighborhoods. Fig-5(d) Optimal Surface Finding 6. CONCLUSIONS The fully automated segmentation of lungs with Lung cancer regions was presented. The robustness and effectiveness of our advance was demonstrated on 30 lung scans containing 20 normal lungs and 40 diseased. Lungs where usual segmentation methods frequentlyfail todeliver usable results. Low segmentation errors were achieved in cases with and without high-density pathology,compared to two clinically utilized methods. The presented approach to lung segmentation exposesnewavenuesforcomputer-aided lung image analysis. A core component of our method may be a novel robust ASM matching method. The approach not only allows addressing disturbances but it is also well suitable for large shape modelsandparallel implementation, allowing low computationtimes.OurrobustASMframework is additionally applicable to other segmentation problems furthermore as imaging modalities, requiring mainly an adaption of the matching cost function. REFERENCES [1] S. G. Armato and W. F. Sensakovic, “Automated lung segmentation for thoracic CT,” Acad. Radiol., vol. 11, no. 9, pp. 1011–1021, 2004. [2] J. K. Leader, B. Zheng, R. M. Rogers, F. C. Sciurba, A. Perez, B. E. Chapman, S. Patel, C. R. Fuhrman, and D. Gur, “Automated lung segmentation in X-ray computed tomography,” Acad. Radiol., vol. 10, no. 11, pp. 1224–1236, 2003.
  • 4. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 07 Issue: 03 | Mar 2020 www.irjet.net p-ISSN: 2395-0072 © 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 5281 [3] A. Silva, J. S. Silva, B. S. Santos, and C. Ferreira, “Fast pulmonary contour extraction in X-ray CT images: A methodology and quality assessment,” in Proc. SPIE Med. Imag., 2001, vol. 4321, pp. 216–224. [4] S. Hu, E. A. Hoffman, and J. M. Reinhardt, “Automatic lung segmentation for accurate quantitation of volumetric X-ray CT image,” IEEE Trans. Med. Imag., vol. 20, no. 6, pp. 490– 498, Jun. 2001. [5] E. A. Hoffman and E. L. Ritman, “Effectofbodyorientation on regional lung expansion in dogandsloth,” J.Appl.Physiol., vol. 59, no. 2, pp. 481–491, 1985. [6] T. Kitasaka, K. Mori, J. Hasegawa, and J. Toriwaki, “Lung area extraction from 3-D chest X-ray CT images using a shape model generated by a variable Bézier surface,” Syst. Comput. Jpn., vol. 34, no. 4, pp. 60–71, 2003. [7] J. Pu, J. Roos, C. A.Yi, S. Napel, G. D. Rubin, and D. S. Paik, “Adaptive border marching algorithm: Automatic lung segmentation on chest CT images,” Computer. Med. Imag. Graph., vol. 32, no. 6, pp. 452–462, 2008. [8] J. Pu, D. S. Paik, X. Meng, J. E. Roos, and G. D. Rubin, “Shape breakand- repair strategy and its application to automated medical image segmentation,” IEEE Trans. Vis. Comput. Graphics, vol. 17, no. 1, pp. 115–124, Jan. 2011.