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Pulmonary Hydatid Cyst
By :Darayus P.Gazder (DPG)
 Echinoccosis or hydatid disease is caused by
larval stage of the echinococcus tapeworm
 Four species
 E. granulosis
 E. multilocularis
 E. vogeli
 E. oligarthrus
 Vast majority of infestations in humans are
caused by echinococcus granulosis
 Worldwide distrubution are concentrated in sheep
raising areas
Map shows areas in which hydatid disease is endemic due to the transmission of E
granulosus by means of the dog-sheep cycle (solid red areas).
Red stripes indicate areas where transmission occurs by means of alternative life cycles in which carnivores such as
wolves and foxes serve as definitive hosts and goats, camels, and horses serve as intermediate hosts
CLINICAL FEATURES
 Lungs are the second most common site of haematogenous
spread in adults
 INCIDENCE
Rural > Urban
Male:Female ----- 5:1
Lower lobes R>L
AGE: 20-40 Years (MC)
Most common site in children (25%)
Pulmonary increase in size 1-5cm per year
Symptoms: Chest pain, cough, haemoptysis, dyspnoea,
fever, salty sputum, allergy, fragments of hydatid
membrane or scolices
Investigations:
 Chest X-ray:
1. Dense homogeneous opacity
2. Crescenteric cap of air
3. Water lily Appearance.
 Blood shows eosinophilia: 15-20%
 Positive Casoni’s test: +ve in 50% of cases.
 Serodiagnosis: Detection on antigen/ antibodies due to parasite by Elisa
 Indirect hemagglutination test: +ve in 60-100% cases
A fixed amount of anti-echinococcus antibodies is mixed with fixed amount of red blood
cells coated with antigens. A positive IHA test is indicated by formation of the a ‘mat’ or
‘carpet’ cells at the bottom of the well.
 CT scan diagnostic
Unruptured echinococcus cysts
Crescent sign-cap of air, when it communicates into bronchial tree.
Consider this as sign of impending rupture and indication for emergency
thoracotomy
Complications
 Pulmonary Embolism
 Rupture -- allergic symptoms and anaphylaxis
-severe hypotension and death
 Rupture - trans bronchial spread to other lobes/
pleural effusion/ Pneumothorax/ Anaphylaxis
 Hepatobronchial fistula formation (produces
bilious sputum)
 Infection -- abscess formation and septicemia
 Calcification - rare
D/D
 Lung cancer
 Lung abscess
 Epithelial cysts
 Aspergillosis
MANAGEMENT
 Small cyst< 2-3 cm-----Medical treatment –
Albendazole- 3-4 weeks
 Larger cysts>4-6 cm---- Surgical resection, preop
Albendazole atleast 4days prior to surgery and
continue for 3-6 months after surgery.
 IF THE HYDATID CYST OCCUPIES MORE THAN
50% OF A LOBE ----- LOBECTOMY
Surgery is considered the treatment of choice
Parasite can be completely removed and the patient cured.
Prevent spill of cyst contents to avoid intra-operative
dissemination and recurrence
 Delivery of intact cyst
 Cyst fluid aspiration ± use of scolicidal solution
 Hypertonic saline, povidine iodine, formalin, ethanol,
hydrogen peroxide, 1% formalderhyde
 Agent must remain in contact with cyst for at least 15
minutes
Prevention:
 Avoid close contact with dogs.
 Wash hands after handling of dogs.
 Avoid contact with dog feces.
 Vegetables, fruit should be thoroughly washed.
 Prevent dogs from roaming or having access to
raw sheep meat or viscera.
 All sheep carcasses should be disposed of
correctly and immediately.
Thank you!!
References
Baileys and Love’ Short Practice of Surgery
Manipal manual of Surgery
SRB Manual of Surgery
Bedside Clinics in Surgery
http://radiographics.rsna.org
www.emedicine.com
Hydatid cyst

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Hydatid cyst

  • 1. Pulmonary Hydatid Cyst By :Darayus P.Gazder (DPG)
  • 2.  Echinoccosis or hydatid disease is caused by larval stage of the echinococcus tapeworm  Four species  E. granulosis  E. multilocularis  E. vogeli  E. oligarthrus  Vast majority of infestations in humans are caused by echinococcus granulosis  Worldwide distrubution are concentrated in sheep raising areas
  • 3. Map shows areas in which hydatid disease is endemic due to the transmission of E granulosus by means of the dog-sheep cycle (solid red areas). Red stripes indicate areas where transmission occurs by means of alternative life cycles in which carnivores such as wolves and foxes serve as definitive hosts and goats, camels, and horses serve as intermediate hosts
  • 4.
  • 5. CLINICAL FEATURES  Lungs are the second most common site of haematogenous spread in adults  INCIDENCE Rural > Urban Male:Female ----- 5:1 Lower lobes R>L AGE: 20-40 Years (MC) Most common site in children (25%) Pulmonary increase in size 1-5cm per year Symptoms: Chest pain, cough, haemoptysis, dyspnoea, fever, salty sputum, allergy, fragments of hydatid membrane or scolices
  • 6. Investigations:  Chest X-ray: 1. Dense homogeneous opacity 2. Crescenteric cap of air 3. Water lily Appearance.  Blood shows eosinophilia: 15-20%  Positive Casoni’s test: +ve in 50% of cases.  Serodiagnosis: Detection on antigen/ antibodies due to parasite by Elisa  Indirect hemagglutination test: +ve in 60-100% cases A fixed amount of anti-echinococcus antibodies is mixed with fixed amount of red blood cells coated with antigens. A positive IHA test is indicated by formation of the a ‘mat’ or ‘carpet’ cells at the bottom of the well.  CT scan diagnostic
  • 8. Crescent sign-cap of air, when it communicates into bronchial tree. Consider this as sign of impending rupture and indication for emergency thoracotomy
  • 9.
  • 10. Complications  Pulmonary Embolism  Rupture -- allergic symptoms and anaphylaxis -severe hypotension and death  Rupture - trans bronchial spread to other lobes/ pleural effusion/ Pneumothorax/ Anaphylaxis  Hepatobronchial fistula formation (produces bilious sputum)  Infection -- abscess formation and septicemia  Calcification - rare
  • 11. D/D  Lung cancer  Lung abscess  Epithelial cysts  Aspergillosis
  • 12. MANAGEMENT  Small cyst< 2-3 cm-----Medical treatment – Albendazole- 3-4 weeks  Larger cysts>4-6 cm---- Surgical resection, preop Albendazole atleast 4days prior to surgery and continue for 3-6 months after surgery.  IF THE HYDATID CYST OCCUPIES MORE THAN 50% OF A LOBE ----- LOBECTOMY
  • 13. Surgery is considered the treatment of choice Parasite can be completely removed and the patient cured. Prevent spill of cyst contents to avoid intra-operative dissemination and recurrence  Delivery of intact cyst  Cyst fluid aspiration ± use of scolicidal solution  Hypertonic saline, povidine iodine, formalin, ethanol, hydrogen peroxide, 1% formalderhyde  Agent must remain in contact with cyst for at least 15 minutes
  • 14. Prevention:  Avoid close contact with dogs.  Wash hands after handling of dogs.  Avoid contact with dog feces.  Vegetables, fruit should be thoroughly washed.  Prevent dogs from roaming or having access to raw sheep meat or viscera.  All sheep carcasses should be disposed of correctly and immediately. Thank you!!
  • 15. References Baileys and Love’ Short Practice of Surgery Manipal manual of Surgery SRB Manual of Surgery Bedside Clinics in Surgery http://radiographics.rsna.org www.emedicine.com

Editor's Notes

  1. Australia, Africa and Wales.
  2. Proctoscolex, Scolex, Intestine:::DOG::::: EGG is Ingested Embryos are released….it enters the portal circulation….The parasite then grows to form a cyst filled with fluid. Pericyst Outer layer Composed of inflamed fibrous tissue derived from the host Form a dense and fibrous protective zone Ectocyst Middle layer Acellular, laminated membrane Endocyst Innermost layer Germinative layer Gives rise to secondary cysts / brood capsules / daughter cysts
  3. Multiple in 30% of cases Bilateral in 20% of cases Located in lower lobes 60% of cases Calcification rare 0.7%
  4. Uncomplicated cysts Well defined, homogenous, round to oval masses Surrounded by normal lung tissue May vary from 1-20cm in size Cyst shape may vary on inspiratory and expiratory films (or supine and erect)
  5. Cyst growth causes erosions in the bronchioles that are included in the pericyst Air is introduced between the pericyst and the laminated membrane Air collection appears as a thin radiolucent crescent in the upper part of the cyst Known as the crescent or meniscus sign Some authors consider this as sign of impending rupture and indication for emergency thoracotomy
  6. Collapsed laminated membrane produces an irregular projection in a fluid level due to rupture of the cyst-
  7. Albendazole: Gut absorption, Teratogenic….Allergic reaction…Prevent local recurrence, Cant be treated, multiple cysts Medical therapy starts &amp;gt; 4 days prior to surgery and continues for 3-6 months