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22/04/13	
  
1	
  
Protein, Carbs & GI
What’s the Latest?
Dr Helen O’Connor APD1
Senior Lecturer Nutrition
University of Sydney
Overview
Scientific Evidence for Higher Protein Diets
›  What is a higher protein diet?
›  How much protein do we need?
›  Weight management
-  Lighter and leaner
-  Metabolic health
-  Nutrient density
-  Appetite & eating behaviour
Carbs – The Good, The Bad & Secrets to Success
›  Evidence for low GI carbs
›  Secrets to Success
2
What is a Higher Protein Diet?
Nutrient Guidelines1 Paleo2 Hi-Protein3
Protein (%E) 15-25 34 25-35
Fat (%E) 20-35 21 10-30
Carb (%E) 45-65 45 35-65
3
1NHMRC; 2Eaton & Kroner 1985; 3Wycherley et al 2012
How Much Protein Do We Need?
›  Evidence of a ‘set point’ requirement for protein
›  Different requirement across species
›  Eating continues until protein requirement is reached
›  Known as ‘Protein Leverage Hypothesis’
Case Example
›  Energy Needs 10,700 kJ/day
›  Estimated protein requirement (1500 kJ/day)
›  Remainder from carbs and fat (9,200 kJ/day)
›  You keep eating until protein intake is satisfied
4
Excess CHO/Fat
consumed to meet
Protein target
Eaten quota of CHO + Fat but still
eating to get Protein requirement
Eaten quota of kJ but still short of protein
Protein Leverage Hypothesis
5
Range of possible diet rails to meet protein target
More energy consumed to
meet Protein target
Less energy
to meet protein
target
6
High Protein Diets & Weight Loss
Wycherley et al 2012
22/04/13	
  
2	
  
High Protein Diets & Fat Loss
7
Wycherley et al 2012
High Protein Diets & Lean Mass
8
Wycherley et al 2012
Case Study: Pete
9
›  52 yrs old, overweight
›  Metabolic syndrome
›  Office worker, gym 3/wk

Protein close to exercise is beneficial for hypertrophy in
young men
Cribb & Hayes Med Sci Sports Exerc 2006
Protein Window
Protein around
the time of
training
improves gains
in lean mass
Timing of Protein Intake
Cribb & Hayes Med Sci Sports Exerc 2006
Timing right also
translated into
improved
strength gains
Case Study: Samantha
12
›  21 y; few kg overweight
›  Feels fatter than she really is
›  Low iron & tired
›  Training every day
›  Frustrated with weight loss
Weight Gain in Young Women
› Moving away from home
› Busy with work and/or study
› Eating out and alcohol
› Limited shopping/cooking skills
› Budget constraints
› Decline in physical activity
› Cohabitation (friends or partner)
› Marriage & pregnancy
› Limited research on young women Ball et al 2002
22/04/13	
  
3	
  
Weight Gain Greatest in Young Women
13
http://www.alswh.org.au/
Young Women
(n=5770)
Mid-age Women
(n=8942)
Older Women
(n=6777)
649
(95% CI: 620-678)
492
(95% CI: 467-516)
162
(95% CI: 185-140)
Australian Longitudinal Study of Women’s Health
Weight Gain (g/year) 1996-2003
Popkin 2010 – review 1990-2000
Risks of Weight Gain in Young Women
› Weight Tracks Upward
- Negative physical & mental health
› Reproductive Health
- Infertility
- Obstetric complications
- Epigenetic effects for off spring
› Family & Future Health
- Women decide family meals
- Modelling health behaviour important
- Vicious cycle for future generations
14
Macronutrients Study Diets & Exercise
Nutrient HP Diet HC Diet
Energy (kJ) 5615 5602
Protein (g) 107 (32% of E) 67 (20% of E)
Carbohydrate (g) 138 (41% of E) 191 (58% of E)
Sugars (g) 73 83
GI/GL 46/61 52/93
Dietary fibre (g) 23 24
Total fat (g) 38 (25% of E) 32 (21% of E)
Saturated fat (g) 11 10
Cholesterol (mg) 298 87
30 min accumulated physical activity daily (activity diary)
Weight Loss
16
P=0.06
P=0.16
Iron Deficiency in Overweight/Obese
Young Women
17
1.  Ahmed et al 2008
2.  Fayet & Samman 2007
4. Manuscript under review
Possibly
higher
prevalence in
younger
women?
Micronutrients - Study Diets
Nutrient EAR/AI HP Diet HC Diet
Thiamin (mg) 0.9 1.6 1.8
Riboflavin (mg) 0.9 2.5 2.5
Niacin Equiv (mg) 11 47 32
Vitamin C (mg) 30 156 160
Total Folate (µg) 320 332 355
Vitamin A Equiv (µg) 500 1058 1307
Sodium (mg) 460-920 2186 1940
Potassium (mg) 2800 3554 3096
Magnesium (mg) 255 318 268
Calcium (mg) 840 908 877
Phosphorus (mg) 580 1725 1282
Iron (mg) 8.0 12.2 9.9
Zinc (mg) 6.5 11.7 7.6
Red meat
4 times a
week only
nutrient
still short
(70%) of
the RDI.
More
Haeme
iron than
HC
22/04/13	
  
4	
  
Nutrient Density of Higher Protein Diet
19
Bioavailability is
Important
Iron Stores Maintained Better on HP Diet
20
-­‐10	
  
-­‐5	
  
0	
  
5	
  
10	
  
15	
  
20	
  
0	
   6	
   12	
  
Ferri%n	
  (µgL-­‐1)	
  
Time	
  (months)	
  
Self esteem also increased more on HP diet
Too Tired to Lose Weight?
21
Food, Mood & Mind Study
Hunger & Desire to Eat
22
0
1
2
3
4
5
6
Baseline 3	
  months 6	
  months 12	
  months
Hunger	
  VAS	
  Score
Higher	
  Protein	
  Diet	
  (n=21) Higher	
  Carbohydrate	
  Diet	
  (n=15)
p =0.525 p =0.070
p =0.227p =0.974
0
1
2
3
4
5
6
Baseline 3	
  months 6	
  months 12	
  months
Desire	
  to	
  Eat	
  VAS	
  Score
Higher	
  Protein	
  Diet	
  (n=21) Higher	
  Carbohydrate	
  Diet	
  (n=15)
p =0.316 p =0.059p =0.184
p =0.939
Repeated Measures ANOVA:
Diet: 0.184; Diet*Time: 0.229; Time: 0.459
Repeated Measures ANOVA:
Diet: 0.138; Diet*Time: 0.337; Time: 0.203
VAS: Hunger extremely hungry not at all hungry
Desire extremely strong not at all strong
Hunger & Desire to Eat Lower on HP Diet
Diogenes Weight Maintenance
23
LP-HGI &
Control
Most Weight
Regain
HP or LGI
alone
moderate
benefit
0.93 kg less
gain in HP &
0.95 kg less
in low GI
HP-LGI
best
Larsen et al 2010
Case Study: Robyn
24
•  36 y; training for a marathon
•  Following paleo diet
•  Tired & not getting results
Romjin et al 1984
Robyn is Training LOW
LOW carbs = SLOW times
Delayed Recovery
Robyn needs carbs to get
some quality ‘train high’
22/04/13	
  
5	
  
Train Low in Well Trained
Yeo et al 2008; JAP 105 (5); 1462-1470
Low unable
to maintain
intensity
during HIIT
despite
financial
incentives
Marathon Des Sables -Toughest Footrace on Earth
26
Paleo Runner: http://www.youtube.com/watch?v=2eFQs7bu-P8&noredirect=1
Stage Tom Wyles
(Paleo)
Mr Inexperienced#
(Carbs)
1 235 302*
2 185 47
3 207 40
4 99 36
5 62 28
Finish 118 46
* Finished 96th but incurred 1 h penalty for not filling out form correctly
after medical treatment for sore feet
#Mr Inexperienced advised by Dr Greg Cox Sports Dietitian AIS
Secrets to Success
› Fresh produce
› Varied diet (healthyeatingquiz.com.au)
› Higher protein, moderate carb intake
› Low GI carbs for health & weight loss
› Nutritional balance
› Iron is limiting nutrient – leads to tiredness
› Tired clients train poorly and lower diet compliance
› Top gear training needs ‘right carbs’
27
‘When the training gets tough, the tough eat enough carbs’
Professor Louise Burke, AIS
Libby Trickett 2009
Olympian
Freestyle & Fly
Questions
28

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Helen O'Connor - Proteins, Carbs & GI. What's the latest?

  • 1. 22/04/13   1   Protein, Carbs & GI What’s the Latest? Dr Helen O’Connor APD1 Senior Lecturer Nutrition University of Sydney Overview Scientific Evidence for Higher Protein Diets ›  What is a higher protein diet? ›  How much protein do we need? ›  Weight management -  Lighter and leaner -  Metabolic health -  Nutrient density -  Appetite & eating behaviour Carbs – The Good, The Bad & Secrets to Success ›  Evidence for low GI carbs ›  Secrets to Success 2 What is a Higher Protein Diet? Nutrient Guidelines1 Paleo2 Hi-Protein3 Protein (%E) 15-25 34 25-35 Fat (%E) 20-35 21 10-30 Carb (%E) 45-65 45 35-65 3 1NHMRC; 2Eaton & Kroner 1985; 3Wycherley et al 2012 How Much Protein Do We Need? ›  Evidence of a ‘set point’ requirement for protein ›  Different requirement across species ›  Eating continues until protein requirement is reached ›  Known as ‘Protein Leverage Hypothesis’ Case Example ›  Energy Needs 10,700 kJ/day ›  Estimated protein requirement (1500 kJ/day) ›  Remainder from carbs and fat (9,200 kJ/day) ›  You keep eating until protein intake is satisfied 4 Excess CHO/Fat consumed to meet Protein target Eaten quota of CHO + Fat but still eating to get Protein requirement Eaten quota of kJ but still short of protein Protein Leverage Hypothesis 5 Range of possible diet rails to meet protein target More energy consumed to meet Protein target Less energy to meet protein target 6 High Protein Diets & Weight Loss Wycherley et al 2012
  • 2. 22/04/13   2   High Protein Diets & Fat Loss 7 Wycherley et al 2012 High Protein Diets & Lean Mass 8 Wycherley et al 2012 Case Study: Pete 9 ›  52 yrs old, overweight ›  Metabolic syndrome ›  Office worker, gym 3/wk  Protein close to exercise is beneficial for hypertrophy in young men Cribb & Hayes Med Sci Sports Exerc 2006 Protein Window Protein around the time of training improves gains in lean mass Timing of Protein Intake Cribb & Hayes Med Sci Sports Exerc 2006 Timing right also translated into improved strength gains Case Study: Samantha 12 ›  21 y; few kg overweight ›  Feels fatter than she really is ›  Low iron & tired ›  Training every day ›  Frustrated with weight loss Weight Gain in Young Women › Moving away from home › Busy with work and/or study › Eating out and alcohol › Limited shopping/cooking skills › Budget constraints › Decline in physical activity › Cohabitation (friends or partner) › Marriage & pregnancy › Limited research on young women Ball et al 2002
  • 3. 22/04/13   3   Weight Gain Greatest in Young Women 13 http://www.alswh.org.au/ Young Women (n=5770) Mid-age Women (n=8942) Older Women (n=6777) 649 (95% CI: 620-678) 492 (95% CI: 467-516) 162 (95% CI: 185-140) Australian Longitudinal Study of Women’s Health Weight Gain (g/year) 1996-2003 Popkin 2010 – review 1990-2000 Risks of Weight Gain in Young Women › Weight Tracks Upward - Negative physical & mental health › Reproductive Health - Infertility - Obstetric complications - Epigenetic effects for off spring › Family & Future Health - Women decide family meals - Modelling health behaviour important - Vicious cycle for future generations 14 Macronutrients Study Diets & Exercise Nutrient HP Diet HC Diet Energy (kJ) 5615 5602 Protein (g) 107 (32% of E) 67 (20% of E) Carbohydrate (g) 138 (41% of E) 191 (58% of E) Sugars (g) 73 83 GI/GL 46/61 52/93 Dietary fibre (g) 23 24 Total fat (g) 38 (25% of E) 32 (21% of E) Saturated fat (g) 11 10 Cholesterol (mg) 298 87 30 min accumulated physical activity daily (activity diary) Weight Loss 16 P=0.06 P=0.16 Iron Deficiency in Overweight/Obese Young Women 17 1.  Ahmed et al 2008 2.  Fayet & Samman 2007 4. Manuscript under review Possibly higher prevalence in younger women? Micronutrients - Study Diets Nutrient EAR/AI HP Diet HC Diet Thiamin (mg) 0.9 1.6 1.8 Riboflavin (mg) 0.9 2.5 2.5 Niacin Equiv (mg) 11 47 32 Vitamin C (mg) 30 156 160 Total Folate (µg) 320 332 355 Vitamin A Equiv (µg) 500 1058 1307 Sodium (mg) 460-920 2186 1940 Potassium (mg) 2800 3554 3096 Magnesium (mg) 255 318 268 Calcium (mg) 840 908 877 Phosphorus (mg) 580 1725 1282 Iron (mg) 8.0 12.2 9.9 Zinc (mg) 6.5 11.7 7.6 Red meat 4 times a week only nutrient still short (70%) of the RDI. More Haeme iron than HC
  • 4. 22/04/13   4   Nutrient Density of Higher Protein Diet 19 Bioavailability is Important Iron Stores Maintained Better on HP Diet 20 -­‐10   -­‐5   0   5   10   15   20   0   6   12   Ferri%n  (µgL-­‐1)   Time  (months)   Self esteem also increased more on HP diet Too Tired to Lose Weight? 21 Food, Mood & Mind Study Hunger & Desire to Eat 22 0 1 2 3 4 5 6 Baseline 3  months 6  months 12  months Hunger  VAS  Score Higher  Protein  Diet  (n=21) Higher  Carbohydrate  Diet  (n=15) p =0.525 p =0.070 p =0.227p =0.974 0 1 2 3 4 5 6 Baseline 3  months 6  months 12  months Desire  to  Eat  VAS  Score Higher  Protein  Diet  (n=21) Higher  Carbohydrate  Diet  (n=15) p =0.316 p =0.059p =0.184 p =0.939 Repeated Measures ANOVA: Diet: 0.184; Diet*Time: 0.229; Time: 0.459 Repeated Measures ANOVA: Diet: 0.138; Diet*Time: 0.337; Time: 0.203 VAS: Hunger extremely hungry not at all hungry Desire extremely strong not at all strong Hunger & Desire to Eat Lower on HP Diet Diogenes Weight Maintenance 23 LP-HGI & Control Most Weight Regain HP or LGI alone moderate benefit 0.93 kg less gain in HP & 0.95 kg less in low GI HP-LGI best Larsen et al 2010 Case Study: Robyn 24 •  36 y; training for a marathon •  Following paleo diet •  Tired & not getting results Romjin et al 1984 Robyn is Training LOW LOW carbs = SLOW times Delayed Recovery Robyn needs carbs to get some quality ‘train high’
  • 5. 22/04/13   5   Train Low in Well Trained Yeo et al 2008; JAP 105 (5); 1462-1470 Low unable to maintain intensity during HIIT despite financial incentives Marathon Des Sables -Toughest Footrace on Earth 26 Paleo Runner: http://www.youtube.com/watch?v=2eFQs7bu-P8&noredirect=1 Stage Tom Wyles (Paleo) Mr Inexperienced# (Carbs) 1 235 302* 2 185 47 3 207 40 4 99 36 5 62 28 Finish 118 46 * Finished 96th but incurred 1 h penalty for not filling out form correctly after medical treatment for sore feet #Mr Inexperienced advised by Dr Greg Cox Sports Dietitian AIS Secrets to Success › Fresh produce › Varied diet (healthyeatingquiz.com.au) › Higher protein, moderate carb intake › Low GI carbs for health & weight loss › Nutritional balance › Iron is limiting nutrient – leads to tiredness › Tired clients train poorly and lower diet compliance › Top gear training needs ‘right carbs’ 27 ‘When the training gets tough, the tough eat enough carbs’ Professor Louise Burke, AIS Libby Trickett 2009 Olympian Freestyle & Fly Questions 28