Healthcare associated infections (HAI) are infections acquired during medical care in hospitals or other healthcare facilities. Some key points:
- HAI affect around 10% of hospital patients and costs are doubled compared to patients without infections. Common sites of infection include urinary, surgical and pneumonia.
- Risk factors for HAI include crowded hospital conditions, patients with compromised immune systems, increasing antibiotic resistance in bacteria. Procedures like catheterization and ventilation also increase risk.
- HAI can be prevented through proper hand hygiene, sterilization of equipment, isolation of infected patients, and avoiding unnecessary medical procedures. Surveillance by infection control teams is also important to reduce infection rates.
Hospital acquired infections: The different common sources of infection, their routes of spread and the growing antimicrobial resistance. Also includes a discussion on hospital Infection prevention and control guidelines and the universal and standard precautions.
HAI are a significant cause of increased morbidity and mortality in hospitalized patients. In addition, HAI lead to prolonged hospital stay, are inconvenient for the patients, and constitute huge economic burden on health care system. Studies have shown that HAI prevalence varies from 3.8% to 19.6% depending on the population surveyed with a pooled global prevalence of 10.1%.
Hospital acquired infections: The different common sources of infection, their routes of spread and the growing antimicrobial resistance. Also includes a discussion on hospital Infection prevention and control guidelines and the universal and standard precautions.
HAI are a significant cause of increased morbidity and mortality in hospitalized patients. In addition, HAI lead to prolonged hospital stay, are inconvenient for the patients, and constitute huge economic burden on health care system. Studies have shown that HAI prevalence varies from 3.8% to 19.6% depending on the population surveyed with a pooled global prevalence of 10.1%.
A short brief on 'Hospital Acquired Infections' (HAI) or 'Nosocomial Infection' (NI) for M Phil, MPH and Advance Course in Hospital Management/ Administration
Central-Line-Associated Bloodstream Infections (CLABSI) pause a major health problem in hospitalized patients. This disease is associated with people with a central line/tube inserted through the skin into the large vein, which can be used to give medicines, fluids, nutrients, or blood products to patients in critical conditions. The disease occurs when microbes enter through the central line invading the bloodstream.
updated guidelines of hospital infection control, as mentioned in the ppt. its not all the guidelines but yes a brief overview and for further details refer to hospital infection control guidelines pdf.which is available in my uploads.
A short brief on 'Hospital Acquired Infections' (HAI) or 'Nosocomial Infection' (NI) for M Phil, MPH and Advance Course in Hospital Management/ Administration
Central-Line-Associated Bloodstream Infections (CLABSI) pause a major health problem in hospitalized patients. This disease is associated with people with a central line/tube inserted through the skin into the large vein, which can be used to give medicines, fluids, nutrients, or blood products to patients in critical conditions. The disease occurs when microbes enter through the central line invading the bloodstream.
updated guidelines of hospital infection control, as mentioned in the ppt. its not all the guidelines but yes a brief overview and for further details refer to hospital infection control guidelines pdf.which is available in my uploads.
NOSOCOMIAL INFECTION OR HOSPITAL ACQUIRED INFECTION
OR HEALTHCARE ASSOCIATED INTECTION CAN BE DEFINED AS THE INFECTION ACQUIRED IN THE HOSPITAL BY A PATIENT:
WHO WAS ADMITTED FOR A REASON OTHER THAT INFECTION
FACTORS AFFECTING HAIS
SOURCES OF INFECTION
MICRORGANISMS RESPONSIBLE FOR INFECTION
TYPES OF HAIS
MODE OF TRANSMISSION
PREVENTION OF HAIS
this presentation is help to the student for the getting information regarding the sorces, types, & mode of infection spread in the hospital sector, it help firstd year student student gain the information regarding through this ppt
Over 1.4 million people each year worldwide suffer from hospital acquired infections. We can follow simple steps and protocols to prevent many of these cases.
Infection prevention in healthcare construction and renovationMoustapha Ramadan
Infection prevention and control in healthcare setting during construction and renovation.
Is really there is a need? What is the role of infection preventionist?
Presentation was given to Labor workers and Engineers
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
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Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
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- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
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Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
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2. HEALTHCARE ASSOCIATED
INFECTION (HAI)
2
Also known as Nosocomial infection /
/Hospital acquired infection
/ Hospital associated infection
Also occupational infections among staff
For patients : Infections that first
appear 48hrs or more after hospital
admission or within 30 days after
discharge.
3. Some Statistics for HAI:
Affects ~ 10% of all in-patients
Delays discharge
Costs 2 x more than if there is
no infection
Show increasing
trend among patients
and staff
3
4. 4
Crowded hospital conditions
New microorganism
Increasing people with
compromised immune system
Increasing Bacterial resistance
(MRSA,resistant Gram negatives)
HAI reducible by 10-
30%
RISE IN HAI AS A RESULT OF 4 FACTORS
5. HAI - EPIDEMIOLOGY
5
Can be exogenous (external organism) and
endogenous (opportunist normal flora)
Host susceptibility : important factor in
development of HAI
MEDICAL EQUIPMENTS AND
PROCEDURES (surgery) are often responsible
for infections
6. HAI :Mode of Transmission
Contact/hand borne (most common)
Air borne
Oral route
Parenteral route
Vector borne
6
7. 1. Contact (most common)
Direct (physical contact)
◦ eg when a staff turns a
patient, gives patient a
bath , examination of
patient
7
8. 8
Indirect-contact Transmission
Involves contact of a host with a contaminated
intermediate object , eg:
Contaminated instruments / needles/dressings
Contaminated gloves that are not changed
between patient.
Contaminated surface by needles (Jarum diletak
atas permukaan selepas ambil darah ! )》》》
Dried blood can transmit HEPATITIS B/C
9. 9
RISIKO HAI
Hep B virus can live outside d body
at least 7 days
Hep C virus can live outside d body
for 16h - 4 days
13. Hospital Procedure Pose Many
Risks to HAI
Nebuliser mask
Catheterization
IV Procedure
Dressing
Bedpans
Urinals
Dirty couch etc.
13
14. Predisposing Factors fOR
HAI
Age ( Young children ,
Elderly )
Severity of Illness
Medical conditions
Immuno compromised
Malnutrition
Obesity
14
15. COMMON SITES OF HAI
Patients in Labour Room / ICU
Patients undergoing invasive
procedures /operation.
Areas of hospital with poor ventilation
15
20. SURGICAL SITE INFECTIONS
20
Frequent
Definition is mainly clinical
(purulent discharge around wounds
or at insertion site of drain, or
spreading cellulites from wounds)
The infections can be exogenously
or endogenously
21. NOSOCOMIAL PNEUMONIA
21
Most important are patients
on ventilators in ICU.
Recent and progressive
radiological opacities of
pulmonary parenchyma,
purulent sputum and recent onset
fever.
22. PREVENTION & CONTROL OF HAI
1. Observance of aseptic technique
2. FREQUENT HAND WASHING
esp. between patients
3. Cleaning, and disinfection of
linen and furniture etc)
22
23. 23
PPE:Wear Gloves
For two reasons:
Provide a protective barrier
and prevent contamination of
hands
Reduce likelihood that
microorganism present on
hands will be transmitted
to patients during procedure.
25. HAND HYGIENETO PREVENT HAI
25
You can get 100s to 1000s of bacteria on your
hands by doing simple tasks like:Assisting pt
up in bed /Touching pt’s gown or bed sheets
HandWashing is Important Because…
80% of disease is spread by your hands.
Hand Hygiene : single most effective
intervention to reduce the cross
transmission of HAI
26. PREVENTION & CONTROL OF HAI
4. Sterilization of instrument eg
nebulizer/oxygen mask/Use of
single-use disposable items
5. Patient isolation eg Pertussis/TB
etc
6. Avoidance of medical
procedures that can lead to HAI
( eg. urinary catheter)
26
27. HAI :What is most Important
Effective surveillance and
action by infection control
team to reduce infection
rates.
Important role of team :
monitor compliance and
practices to prevent HAI
29. HCW - TB Cases & Notification Rate, Malaysia 2003-
2014
Control & Prevention Measures of TB among HCWs
Risk for TB among HCWs is consistently higher than
general population worldwide (Joshi, 2006)
29
31. iii. PPE
• N95 (respirator) must be used in high risk TB
areas
TB ward, chest clinic
Isolation room
Procedure room
eg. sputum induction room
• HCW to use N95
• Patient to use Surgical Mask
Control & Prevention Measures of TB among HCWs
31
32. Control & Prevention Measures of TB among HCWs
Conclusion
In addition to having TB guidelines with
environmental / engineering;
administrative; and respiratory-
protection controls;
HCWs must change their behaviour
towards healthy and safer work culture
in order to prevent & control TB at the
workplace.
32