This document discusses the history and applications of geographic information systems (GIS) with a focus on its use in public health. It provides background on GIS, describing it as a set of tools for collecting, storing, manipulating, and displaying spatial data. The document outlines the history of GIS from early maps in the 1850s to the development of computer-based systems in the 1960s-1980s. It then discusses various uses of GIS in public health including disease mapping and surveillance, environmental health analysis, and health resource planning and accessibility analysis. Specific examples of GIS applications in Nepal are also mentioned.