Myeloma is a cancer of plasma cells that develops in the bone marrow. It causes abnormalities in plasma cells which invade and destroy bone tissue, causing pain, fractures, and other symptoms. Risk factors include genetic abnormalities and exposure to chemicals, radiation, or certain infections. Diagnosis involves blood and urine tests, bone marrow biopsy, and imaging to detect myeloma cells and bone damage. While rarely curable, myeloma is treatable through chemotherapy, stem cell transplantation, radiation, and surgery to strengthen weakened bones. Nursing care focuses on monitoring the patient, providing psychological support, preventing infections, and educating the patient and family.
Neurocysticercosis is a condition caused by the larva of the pork tapeworm (Taenia solium) becoming encysted in human brain tissue. It is most common in developing countries where sanitation is poor and pigs have access to human feces. Common symptoms include seizures, focal neurological deficits, increased intracranial pressure, and hydrocephalus. Diagnosis involves history, physical exam, CT/MRI imaging, and stool studies. Treatment consists of antiparasitic medications like praziquantel or albendazole as well as surgery for complications like hydrocephalus. Nursing care focuses on monitoring for increased intracranial pressure and seizures while providing patient education.
This document provides an overview of neurocysticercosis (NCC), a parasitic infection of the central nervous system caused by the larval stage of the pork tapeworm Taenia solium. It discusses the history, pathogenesis, classification, clinical presentations, investigations, diagnostic criteria, differential diagnosis and treatment of NCC. NCC is endemic in many developing regions and a common cause of adult-onset epilepsy. It can present in different forms depending on the location and stage of the cysts in the brain or spinal cord, with common symptoms including seizures, headache, stroke and hydrocephalus. Diagnosis involves immunological testing of serum and CSF as well as brain imaging.
Amoebic colitis is an infection of the colon caused by the Entamoeba histolytica parasite. It often causes flask-shaped ulcers in the ascending colon, sigmoid colon, or rectum. The ulcers form as small microulcerations that enlarge over time. Numerous trophozoites can be seen at the ulcer margins. Large ulcers show extensive necrosis with an inflamed, thickened intestinal wall. Complications can include liver abscess, effusions in the pleura or pericardium, or hepatobronchial fistulas. Patients experience abdominal pain, cramping, and bloody diarrhea. Diagnosis involves identifying E. histolytica trophozoites on a PAS stain of
This document provides information about cholelithiasis (gallstones). It defines cholelithiasis as the presence of stones in the gallbladder, which are usually composed of cholesterol, calcium salts, and bile pigments. Risk factors include a high-fat diet, obesity, rapid weight loss, older age, alcoholism, diabetes, lack of physical activity, and family history. Symptoms may include abdominal pain, nausea, and jaundice. Diagnosis involves ultrasound, CT scans, cholangiography, and ERCP. Treatment options include surgery (open or laparoscopic cholecystectomy), stone dissolution, diet modification, and pain medication. Complications can include cholangitis, pancreatitis,
Portal hypertension occurs when blood pressure increases in the portal venous system, which normally carries blood from the gastrointestinal tract to the liver. It is defined as a hepatic venous pressure gradient over 10mm Hg. There are three types - pre-hepatic, intra-hepatic, and post-hepatic - depending on the site of vascular obstruction. Common causes include cirrhosis, schistosomiasis, and portal vein thrombosis. Clinical manifestations involve complications from increased portosystemic shunting and include ascites, esophageal varices, hemorrhoids, and hepatic encephalopathy. Diagnostic evaluations involve blood tests, imaging, and endoscopy. Treatment options include medications, endoscopic therapy, TIPS procedure,
Mallory-Weiss syndrome and corrosive injury are caused by vomiting and corrosive ingestion respectively, leading to tears in the gastric mucosa or esophagus. GERD is caused by reflux of gastric acid into the esophagus due to incompetence of the lower esophageal sphincter, resulting in inflammation and ulcers. Hiatal hernia is a protrusion of the stomach through the esophageal hiatus that can cause reflux. Barret's esophagus is a complication of longstanding GERD where the esophageal mucosa is replaced by intestinal metaplasia, increasing the risk of esophageal adenocarcinoma.
Upper gastrointestinal bleeding is a common cause of hospitalization that can be life-threatening. It occurs at a rate of 100 cases per 100,000 people per year. Common causes are peptic ulcers, esophagitis, esophageal varices, and Mallory-Weiss tears. Management involves stabilizing the patient, monitoring for signs of bleeding and shock, transfusing blood products if needed, and locating the source of bleeding via endoscopy to stop it using methods like cauterization or banding.
Myeloma is a cancer of plasma cells that develops in the bone marrow. It causes abnormalities in plasma cells which invade and destroy bone tissue, causing pain, fractures, and other symptoms. Risk factors include genetic abnormalities and exposure to chemicals, radiation, or certain infections. Diagnosis involves blood and urine tests, bone marrow biopsy, and imaging to detect myeloma cells and bone damage. While rarely curable, myeloma is treatable through chemotherapy, stem cell transplantation, radiation, and surgery to strengthen weakened bones. Nursing care focuses on monitoring the patient, providing psychological support, preventing infections, and educating the patient and family.
Neurocysticercosis is a condition caused by the larva of the pork tapeworm (Taenia solium) becoming encysted in human brain tissue. It is most common in developing countries where sanitation is poor and pigs have access to human feces. Common symptoms include seizures, focal neurological deficits, increased intracranial pressure, and hydrocephalus. Diagnosis involves history, physical exam, CT/MRI imaging, and stool studies. Treatment consists of antiparasitic medications like praziquantel or albendazole as well as surgery for complications like hydrocephalus. Nursing care focuses on monitoring for increased intracranial pressure and seizures while providing patient education.
This document provides an overview of neurocysticercosis (NCC), a parasitic infection of the central nervous system caused by the larval stage of the pork tapeworm Taenia solium. It discusses the history, pathogenesis, classification, clinical presentations, investigations, diagnostic criteria, differential diagnosis and treatment of NCC. NCC is endemic in many developing regions and a common cause of adult-onset epilepsy. It can present in different forms depending on the location and stage of the cysts in the brain or spinal cord, with common symptoms including seizures, headache, stroke and hydrocephalus. Diagnosis involves immunological testing of serum and CSF as well as brain imaging.
Amoebic colitis is an infection of the colon caused by the Entamoeba histolytica parasite. It often causes flask-shaped ulcers in the ascending colon, sigmoid colon, or rectum. The ulcers form as small microulcerations that enlarge over time. Numerous trophozoites can be seen at the ulcer margins. Large ulcers show extensive necrosis with an inflamed, thickened intestinal wall. Complications can include liver abscess, effusions in the pleura or pericardium, or hepatobronchial fistulas. Patients experience abdominal pain, cramping, and bloody diarrhea. Diagnosis involves identifying E. histolytica trophozoites on a PAS stain of
This document provides information about cholelithiasis (gallstones). It defines cholelithiasis as the presence of stones in the gallbladder, which are usually composed of cholesterol, calcium salts, and bile pigments. Risk factors include a high-fat diet, obesity, rapid weight loss, older age, alcoholism, diabetes, lack of physical activity, and family history. Symptoms may include abdominal pain, nausea, and jaundice. Diagnosis involves ultrasound, CT scans, cholangiography, and ERCP. Treatment options include surgery (open or laparoscopic cholecystectomy), stone dissolution, diet modification, and pain medication. Complications can include cholangitis, pancreatitis,
Portal hypertension occurs when blood pressure increases in the portal venous system, which normally carries blood from the gastrointestinal tract to the liver. It is defined as a hepatic venous pressure gradient over 10mm Hg. There are three types - pre-hepatic, intra-hepatic, and post-hepatic - depending on the site of vascular obstruction. Common causes include cirrhosis, schistosomiasis, and portal vein thrombosis. Clinical manifestations involve complications from increased portosystemic shunting and include ascites, esophageal varices, hemorrhoids, and hepatic encephalopathy. Diagnostic evaluations involve blood tests, imaging, and endoscopy. Treatment options include medications, endoscopic therapy, TIPS procedure,
Mallory-Weiss syndrome and corrosive injury are caused by vomiting and corrosive ingestion respectively, leading to tears in the gastric mucosa or esophagus. GERD is caused by reflux of gastric acid into the esophagus due to incompetence of the lower esophageal sphincter, resulting in inflammation and ulcers. Hiatal hernia is a protrusion of the stomach through the esophageal hiatus that can cause reflux. Barret's esophagus is a complication of longstanding GERD where the esophageal mucosa is replaced by intestinal metaplasia, increasing the risk of esophageal adenocarcinoma.
Upper gastrointestinal bleeding is a common cause of hospitalization that can be life-threatening. It occurs at a rate of 100 cases per 100,000 people per year. Common causes are peptic ulcers, esophagitis, esophageal varices, and Mallory-Weiss tears. Management involves stabilizing the patient, monitoring for signs of bleeding and shock, transfusing blood products if needed, and locating the source of bleeding via endoscopy to stop it using methods like cauterization or banding.
Pleural effusion is an excess collection of fluid in the pleural space between the lungs and chest wall. It can be caused by conditions like heart failure, tuberculosis, pneumonia, and cancer. Fluid buildup is due to increased production or decreased drainage and can be classified as a transudate or exudate based on its composition. Symptoms include chest pain, cough, and shortness of breath. Diagnosis involves chest x-rays, CT scans, and thoracentesis to analyze pleural fluid. Treatment focuses on the underlying cause as well as draining fluid and using chemicals or surgery to prevent reaccumulation.
Esophagitis is inflammation of the esophagus that is usually caused by acid reflux. Risk factors include obesity, hiatal hernia, smoking, and consuming large amounts of acidic, spicy, or fatty foods. Symptoms include difficulty swallowing, chest pain, and heartburn. Esophagitis is diagnosed through endoscopy, biopsy, or upper GI series X-ray. Dietary management focuses on avoiding irritants like citrus fruits, tomatoes, coffee, and alcohol. Recommended foods include whole grains, lean proteins, bananas, apples, yogurt, and herbal teas. The goals are to prevent pain and reflux while decreasing gastric acidity.
This document discusses liver cirrhosis, including its types, causes, pathophysiology, clinical manifestations, complications, nursing diagnoses, and interventions. Liver cirrhosis is a chronic, degenerative disease characterized by replacement of normal liver tissue with fibrosis that disrupts liver structure and function. Common types are alcoholic cirrhosis and postnecrotic cirrhosis resulting from viral hepatitis. Complications include ascites, hepatic encephalopathy, and esophageal varices, which can lead to life-threatening bleeding if ruptured. Nursing care focuses on reducing metabolic demands, providing adequate nutrition and hydration, preventing infection, and protecting patients from injury and further complications.
A brain abscess is a collection of pus within the brain tissue caused by a bacterial or fungal infection. It most commonly occurs in individuals with compromised immune systems. Common symptoms include fever, headache, nausea and signs of increased intracranial pressure. Diagnosis involves neurological examination, imaging tests and stereotactic biopsy. Treatment consists of long-term intravenous antibiotics along with surgery to drain the abscess if needed. Nursing care focuses on neurological monitoring and supporting the medical and surgical treatment.
This document discusses liver abscesses, including types (pyogenic, amoebic, fungal), causes, risk factors, symptoms, diagnostic tests, and treatment. Pyogenic liver abscess is most common, often caused by bacteria spreading from infections in other organs. Amoebic liver abscess is caused by a parasite and presents with thick pus. Imaging tests can identify abscesses, which are usually treated with antibiotics; drainage may be needed for large abscesses. With treatment, prognosis is generally good especially for amoebic liver abscess.
Encephalitis is an acute inflammation of the brain, usually caused by a viral infection or the immune system attacking brain tissue. It affects 7.4 cases per 100,000 people annually in Western countries. Common causes include herpes simplex virus, rabies virus, and childhood infections. Symptoms include fever, headaches, drowsiness, personality changes, and seizures. Diagnosis involves medical history, physical exam, imaging tests, and spinal tap. Treatment focuses on antiviral drugs, rest, hydration, and rehabilitation to address complications like weakness and memory problems.
Hepatic encephalopathy is one of the deadly complication of liver diseases, occurs due to profound liver failure and from accumulation of ammonia and other toxic metabolites in blood.
Hepatic coma is advanced stage of hepatic encephalopathy.
This document provides information about the diagnosis and management of gastrointestinal bleeding. It discusses:
1) The aim is to understand GI bleeding and provide proper care to patients. Objectives include defining GI bleeding, identifying upper and lower GI bleeding, understanding causes and symptoms, and recognizing diagnostic tests and treatments.
2) GI bleeding can occur anywhere along the gastrointestinal tract from mouth to anus. Upper GI bleeding makes up 70% of cases and lower GI bleeding 30%. Etiologies, signs, symptoms, diagnostic evaluations, and management are discussed for both upper and lower GI bleeding.
3) Workup may include history, physical exam, blood tests, endoscopy, angiography, and imaging. Management focuses on res
This document provides an overview of nephritic and nephrotic syndrome, describing their pathophysiology and clinical features. Nephritic syndrome is characterized by inflammation of the glomeruli, resulting in hematuria, hypertension, and mild proteinuria. Glomerulonephritis causes include post-streptococcal and rapidly progressive crescentic glomerulonephritis. Nephrotic syndrome is caused by increased glomerular permeability, leading to massive proteinuria, hypoalbuminemia, edema, and hyperlipidemia. Specific causes discussed include minimal change disease, membranous nephropathy, focal segmental glomerulosclerosis, and membranoproliferative glomerulone
Glomerulonephritis is an inflammation of the glomerular capillaries in the kidney. It can be caused by an immunological reaction that results in proliferative and inflammatory changes to the glomerular structure. Antigen-antibody complexes form in the blood and become trapped in the glomerular capillaries, inducing an inflammatory response. Glomerulonephritis can present as either a nephrotic syndrome with heavy proteinuria and edema, or a nephritic syndrome with hematuria and decreased kidney function. Treatment involves managing symptoms, preserving kidney function, and treating complications early.
This document provides information about pyelonephritis (kidney infection) including:
1. It defines pyelonephritis as an infection of the kidney and ureters that can be life-threatening.
2. Causes include urinary tract infections ascending from the bladder or entering via the bloodstream.
3. Symptoms vary depending on age but usually include fever, flank pain, nausea, and urinary symptoms.
4. Diagnosis involves urinalysis, urine culture, blood tests and imaging. Treatment is usually antibiotics selected based on likely causative organisms.
Hydronephrosis is a condition where one or both kidneys become swollen due to a blockage in the urinary system. It can be caused by a blockage in the ureters or bladder backing up urine into the kidneys. Symptoms may include flank pain, hematuria, urinary infections, or the condition may be asymptomatic. Diagnosis involves history, physical exam, ultrasound to visualize the kidneys and ureters, IVU to assess the location of blockage, and CT scan to detect stones. Treatment focuses on removing the obstruction, draining excess urine, and antibiotics to prevent infection.
Renal cell carcinoma is a type of kidney cancer that occurs in the lining of the kidney's tubules. Risk factors include older age, smoking, obesity, and high blood pressure. Staging involves determining if the cancer is confined to the kidney or has spread elsewhere. Surgery is often the primary treatment and can involve removing part or all of the affected kidney. Other options include ablation, embolization, radiation, and chemotherapy. Nurses monitor for side effects and provide support to patients undergoing treatment.
definition of hydronephrosis,
causes and types of hydronephrosis
pathophysiology of hydronephrosis
clinical manifestation and diagnostic test for hydronephrosis
management
A 73-year-old male presented with hematuria and irritative voiding symptoms. Further testing revealed high-grade urothelial carcinoma of the bladder that had invaded the bladder muscle. The patient received neoadjuvant chemotherapy followed by robotic cystoprostatectomy and urinary diversion surgery. Bladder cancer is usually transitional cell carcinoma and risk factors include smoking, occupational exposures, and prior radiation. Treatment depends on stage and grade but may include surgery, chemotherapy, and radiation.
Hematemesis- vomiting of blood , a brief studymartinshaji
There can be many causes of hematemesis, such as: bleeding ulcers. prolonged and vigorous retching that causes tears in the esophageal mucosa (known as Mallory-Weiss Syndrome) gastric or intestinal varices.Haematemesis is simply defined as “vomiting blood”. It is caused by bleeding from part of the upper portion of the gastrointestinal tract. It has a wide range of possible causes, depending on the site of blood loss and the tissue that is actively bleeding. Hence it is necessary to analyse and treat the condition perfectly , this is brief study about all the aspects hematemesis ,vomiting of blood including etiology, definition,management ,treatment by drugs etc
please comment
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There are three major forms of liver abscess classified by etiology: pyogenic liver abscess which accounts for 80% of cases, amoebic liver abscess due to E. histolytica accounting for 10% of cases, and fungal abscess accounting for less than 10% of cases. Risk factors include traveling to infection-common areas, older age, medical conditions, medications, alcohol, and poor nutrition. Symptoms include abdominal pain, cough, fatigue, fever, nausea and vomiting, loss of appetite, and jaundice. Diagnosis involves blood tests, imaging, and procedures to drain fluid from the liver. Treatment depends on the cause but may include medications, needle aspiration, catheter drainage, or
This document provides information on cirrhosis of the liver. It defines cirrhosis as a chronic, progressive disease characterized by widespread scarring and nodule formation in the liver. The main causes of cirrhosis include chronic viral hepatitis infections, fatty liver disease, and long-term alcohol abuse. Cirrhosis results in the destruction of liver cells and their replacement with fibrotic scar tissue, impairing blood flow and liver function. Common complications are ascites, bleeding esophageal varices, and hepatic encephalopathy. Diagnosis involves liver enzyme tests, imaging, and biopsy. Treatment focuses on managing complications, restricting alcohol, improving nutrition, and liver transplantation in severe cases.
Portal-systemic encephalopathy is a brain disorder caused by liver dysfunction that allows toxins to reach the brain. It is characterized by alterations in mental status, neurological abnormalities, and distinctive EEG changes. The main underlying mechanism involves increased levels of ammonia in the bloodstream from the gut that are normally processed by the liver. Treatment focuses on reducing ammonia production in the colon through medications like lactulose and restricting protein intake. Prognosis depends on the underlying liver disease and can range from fully treatable acute episodes to chronic and potentially fatal cases.
This document discusses leukopenia, which is a low white blood cell count. It defines leukopenia and outlines its various causes such as cancer, infections, medications, and nutritional deficiencies. Symptoms are related to an increased risk of infection. Diagnosis involves a complete blood count showing low white blood cell levels. Treatment focuses on addressing the underlying cause, using medications to stimulate white blood cell production, following an immunocompromised diet, and preventing infections.
Clostridium perfringens is a Gram-positive, anaerobic bacterium that can cause gas gangrene and food poisoning in humans. It is a normal inhabitant of the intestines that enters the body through wounds or contaminated food. C. perfringens produces several potent toxins that contribute to disease pathogenesis. It is classified into types A-E based on toxin production. Type A causes the majority of food poisoning cases. Gas gangrene results from the proliferation of C. perfringens and other bacteria in wounds producing toxins that damage muscle tissue. Prompt diagnosis and surgical debridement combined with antibiotics are important for treatment.
This document discusses cellulitis, necrotizing fasciitis, and gas gangrene. Cellulitis is a spreading skin infection below the skin surface caused commonly by Streptococcus bacteria. Necrotizing fasciitis is a serious soft tissue infection that spreads rapidly along fascial planes, and risk factors include diabetes and immunosuppression. Gas gangrene is a necrotizing soft tissue infection of muscle caused by Clostridium bacteria, often following trauma. It is characterized by pain, swelling, and crepitus or gas in tissues. Treatment for these conditions involves antibiotics, surgical debridement of infected tissues, and management of the underlying risk factors or injuries.
Pleural effusion is an excess collection of fluid in the pleural space between the lungs and chest wall. It can be caused by conditions like heart failure, tuberculosis, pneumonia, and cancer. Fluid buildup is due to increased production or decreased drainage and can be classified as a transudate or exudate based on its composition. Symptoms include chest pain, cough, and shortness of breath. Diagnosis involves chest x-rays, CT scans, and thoracentesis to analyze pleural fluid. Treatment focuses on the underlying cause as well as draining fluid and using chemicals or surgery to prevent reaccumulation.
Esophagitis is inflammation of the esophagus that is usually caused by acid reflux. Risk factors include obesity, hiatal hernia, smoking, and consuming large amounts of acidic, spicy, or fatty foods. Symptoms include difficulty swallowing, chest pain, and heartburn. Esophagitis is diagnosed through endoscopy, biopsy, or upper GI series X-ray. Dietary management focuses on avoiding irritants like citrus fruits, tomatoes, coffee, and alcohol. Recommended foods include whole grains, lean proteins, bananas, apples, yogurt, and herbal teas. The goals are to prevent pain and reflux while decreasing gastric acidity.
This document discusses liver cirrhosis, including its types, causes, pathophysiology, clinical manifestations, complications, nursing diagnoses, and interventions. Liver cirrhosis is a chronic, degenerative disease characterized by replacement of normal liver tissue with fibrosis that disrupts liver structure and function. Common types are alcoholic cirrhosis and postnecrotic cirrhosis resulting from viral hepatitis. Complications include ascites, hepatic encephalopathy, and esophageal varices, which can lead to life-threatening bleeding if ruptured. Nursing care focuses on reducing metabolic demands, providing adequate nutrition and hydration, preventing infection, and protecting patients from injury and further complications.
A brain abscess is a collection of pus within the brain tissue caused by a bacterial or fungal infection. It most commonly occurs in individuals with compromised immune systems. Common symptoms include fever, headache, nausea and signs of increased intracranial pressure. Diagnosis involves neurological examination, imaging tests and stereotactic biopsy. Treatment consists of long-term intravenous antibiotics along with surgery to drain the abscess if needed. Nursing care focuses on neurological monitoring and supporting the medical and surgical treatment.
This document discusses liver abscesses, including types (pyogenic, amoebic, fungal), causes, risk factors, symptoms, diagnostic tests, and treatment. Pyogenic liver abscess is most common, often caused by bacteria spreading from infections in other organs. Amoebic liver abscess is caused by a parasite and presents with thick pus. Imaging tests can identify abscesses, which are usually treated with antibiotics; drainage may be needed for large abscesses. With treatment, prognosis is generally good especially for amoebic liver abscess.
Encephalitis is an acute inflammation of the brain, usually caused by a viral infection or the immune system attacking brain tissue. It affects 7.4 cases per 100,000 people annually in Western countries. Common causes include herpes simplex virus, rabies virus, and childhood infections. Symptoms include fever, headaches, drowsiness, personality changes, and seizures. Diagnosis involves medical history, physical exam, imaging tests, and spinal tap. Treatment focuses on antiviral drugs, rest, hydration, and rehabilitation to address complications like weakness and memory problems.
Hepatic encephalopathy is one of the deadly complication of liver diseases, occurs due to profound liver failure and from accumulation of ammonia and other toxic metabolites in blood.
Hepatic coma is advanced stage of hepatic encephalopathy.
This document provides information about the diagnosis and management of gastrointestinal bleeding. It discusses:
1) The aim is to understand GI bleeding and provide proper care to patients. Objectives include defining GI bleeding, identifying upper and lower GI bleeding, understanding causes and symptoms, and recognizing diagnostic tests and treatments.
2) GI bleeding can occur anywhere along the gastrointestinal tract from mouth to anus. Upper GI bleeding makes up 70% of cases and lower GI bleeding 30%. Etiologies, signs, symptoms, diagnostic evaluations, and management are discussed for both upper and lower GI bleeding.
3) Workup may include history, physical exam, blood tests, endoscopy, angiography, and imaging. Management focuses on res
This document provides an overview of nephritic and nephrotic syndrome, describing their pathophysiology and clinical features. Nephritic syndrome is characterized by inflammation of the glomeruli, resulting in hematuria, hypertension, and mild proteinuria. Glomerulonephritis causes include post-streptococcal and rapidly progressive crescentic glomerulonephritis. Nephrotic syndrome is caused by increased glomerular permeability, leading to massive proteinuria, hypoalbuminemia, edema, and hyperlipidemia. Specific causes discussed include minimal change disease, membranous nephropathy, focal segmental glomerulosclerosis, and membranoproliferative glomerulone
Glomerulonephritis is an inflammation of the glomerular capillaries in the kidney. It can be caused by an immunological reaction that results in proliferative and inflammatory changes to the glomerular structure. Antigen-antibody complexes form in the blood and become trapped in the glomerular capillaries, inducing an inflammatory response. Glomerulonephritis can present as either a nephrotic syndrome with heavy proteinuria and edema, or a nephritic syndrome with hematuria and decreased kidney function. Treatment involves managing symptoms, preserving kidney function, and treating complications early.
This document provides information about pyelonephritis (kidney infection) including:
1. It defines pyelonephritis as an infection of the kidney and ureters that can be life-threatening.
2. Causes include urinary tract infections ascending from the bladder or entering via the bloodstream.
3. Symptoms vary depending on age but usually include fever, flank pain, nausea, and urinary symptoms.
4. Diagnosis involves urinalysis, urine culture, blood tests and imaging. Treatment is usually antibiotics selected based on likely causative organisms.
Hydronephrosis is a condition where one or both kidneys become swollen due to a blockage in the urinary system. It can be caused by a blockage in the ureters or bladder backing up urine into the kidneys. Symptoms may include flank pain, hematuria, urinary infections, or the condition may be asymptomatic. Diagnosis involves history, physical exam, ultrasound to visualize the kidneys and ureters, IVU to assess the location of blockage, and CT scan to detect stones. Treatment focuses on removing the obstruction, draining excess urine, and antibiotics to prevent infection.
Renal cell carcinoma is a type of kidney cancer that occurs in the lining of the kidney's tubules. Risk factors include older age, smoking, obesity, and high blood pressure. Staging involves determining if the cancer is confined to the kidney or has spread elsewhere. Surgery is often the primary treatment and can involve removing part or all of the affected kidney. Other options include ablation, embolization, radiation, and chemotherapy. Nurses monitor for side effects and provide support to patients undergoing treatment.
definition of hydronephrosis,
causes and types of hydronephrosis
pathophysiology of hydronephrosis
clinical manifestation and diagnostic test for hydronephrosis
management
A 73-year-old male presented with hematuria and irritative voiding symptoms. Further testing revealed high-grade urothelial carcinoma of the bladder that had invaded the bladder muscle. The patient received neoadjuvant chemotherapy followed by robotic cystoprostatectomy and urinary diversion surgery. Bladder cancer is usually transitional cell carcinoma and risk factors include smoking, occupational exposures, and prior radiation. Treatment depends on stage and grade but may include surgery, chemotherapy, and radiation.
Hematemesis- vomiting of blood , a brief studymartinshaji
There can be many causes of hematemesis, such as: bleeding ulcers. prolonged and vigorous retching that causes tears in the esophageal mucosa (known as Mallory-Weiss Syndrome) gastric or intestinal varices.Haematemesis is simply defined as “vomiting blood”. It is caused by bleeding from part of the upper portion of the gastrointestinal tract. It has a wide range of possible causes, depending on the site of blood loss and the tissue that is actively bleeding. Hence it is necessary to analyse and treat the condition perfectly , this is brief study about all the aspects hematemesis ,vomiting of blood including etiology, definition,management ,treatment by drugs etc
please comment
thank u
There are three major forms of liver abscess classified by etiology: pyogenic liver abscess which accounts for 80% of cases, amoebic liver abscess due to E. histolytica accounting for 10% of cases, and fungal abscess accounting for less than 10% of cases. Risk factors include traveling to infection-common areas, older age, medical conditions, medications, alcohol, and poor nutrition. Symptoms include abdominal pain, cough, fatigue, fever, nausea and vomiting, loss of appetite, and jaundice. Diagnosis involves blood tests, imaging, and procedures to drain fluid from the liver. Treatment depends on the cause but may include medications, needle aspiration, catheter drainage, or
This document provides information on cirrhosis of the liver. It defines cirrhosis as a chronic, progressive disease characterized by widespread scarring and nodule formation in the liver. The main causes of cirrhosis include chronic viral hepatitis infections, fatty liver disease, and long-term alcohol abuse. Cirrhosis results in the destruction of liver cells and their replacement with fibrotic scar tissue, impairing blood flow and liver function. Common complications are ascites, bleeding esophageal varices, and hepatic encephalopathy. Diagnosis involves liver enzyme tests, imaging, and biopsy. Treatment focuses on managing complications, restricting alcohol, improving nutrition, and liver transplantation in severe cases.
Portal-systemic encephalopathy is a brain disorder caused by liver dysfunction that allows toxins to reach the brain. It is characterized by alterations in mental status, neurological abnormalities, and distinctive EEG changes. The main underlying mechanism involves increased levels of ammonia in the bloodstream from the gut that are normally processed by the liver. Treatment focuses on reducing ammonia production in the colon through medications like lactulose and restricting protein intake. Prognosis depends on the underlying liver disease and can range from fully treatable acute episodes to chronic and potentially fatal cases.
This document discusses leukopenia, which is a low white blood cell count. It defines leukopenia and outlines its various causes such as cancer, infections, medications, and nutritional deficiencies. Symptoms are related to an increased risk of infection. Diagnosis involves a complete blood count showing low white blood cell levels. Treatment focuses on addressing the underlying cause, using medications to stimulate white blood cell production, following an immunocompromised diet, and preventing infections.
Clostridium perfringens is a Gram-positive, anaerobic bacterium that can cause gas gangrene and food poisoning in humans. It is a normal inhabitant of the intestines that enters the body through wounds or contaminated food. C. perfringens produces several potent toxins that contribute to disease pathogenesis. It is classified into types A-E based on toxin production. Type A causes the majority of food poisoning cases. Gas gangrene results from the proliferation of C. perfringens and other bacteria in wounds producing toxins that damage muscle tissue. Prompt diagnosis and surgical debridement combined with antibiotics are important for treatment.
This document discusses cellulitis, necrotizing fasciitis, and gas gangrene. Cellulitis is a spreading skin infection below the skin surface caused commonly by Streptococcus bacteria. Necrotizing fasciitis is a serious soft tissue infection that spreads rapidly along fascial planes, and risk factors include diabetes and immunosuppression. Gas gangrene is a necrotizing soft tissue infection of muscle caused by Clostridium bacteria, often following trauma. It is characterized by pain, swelling, and crepitus or gas in tissues. Treatment for these conditions involves antibiotics, surgical debridement of infected tissues, and management of the underlying risk factors or injuries.
1) Gangrene is defined as macroscopic necrosis of tissues, and can be dry, wet, or gas gangrene. Dry gangrene is caused by reduced blood flow and progresses slowly, while wet gangrene develops rapidly due to blocked blood flow and favors bacterial growth. Gas gangrene is caused by Clostridium bacteria.
2) Amputation involves surgically removing a body extremity and is indicated for conditions like gangrene, trauma, tumors, and vascular insufficiency. The goals are to remove all infected tissue, achieve wound healing, and provide a stump that can accommodate a prosthesis.
3) Factors in determining the amputation level include the zone of injury, adequate tissue margins, circulation
Cellulitis is a spreading infection of subcutaneous &Fascial planes
Oedema gives rise to soft pitting, while if pus is present ,induration can always be felt
This document discusses necrosis, which refers to cell death and the subsequent morphological changes in tissues. There are several types of necrosis including coagulative, liquefactive, caseous, fat, and fibrinoid necrosis. Coagulative necrosis preserves the basic cell outline while liquefactive necrosis results in tissue liquefaction. Caseous necrosis is seen in tuberculosis and appears cheesy white. Fat necrosis results in calcium deposits in dead fat cells. Fibrinoid necrosis occurs when immune complexes are deposited in blood vessels. Microscopic examination reveals features of cytoplasmic and nuclear changes during necrosis.
NECROTIZING FASCIITIS, GAS GANGRENE AND SEPTIC ARTHRITIS (1).pptxMarilynMonica
Necrotizing fasciitis is a life-threatening soft tissue infection that spreads rapidly along fascial planes. Risk factors include poor wound healing and immunosuppression. It is usually caused by bacteria like Streptococcus and Staphylococcus entering through breaks in the skin. Symptoms include severe pain, fever, and skin changes like blistering. Diagnosis involves imaging tests and the finger test, while treatment requires emergency surgery to remove dead tissue along with broad-spectrum antibiotics. Gas gangrene is caused by Clostridium bacteria contaminating wounds. It causes excruciating muscle pain and swelling along with skin discoloration and gas in tissues. Septic arthritis is a medical emergency where bacteria infect the joints
Necrosis, infarct, gangrene, oedema and congestion involve the death of cells and tissues. Necrosis is the focal death of cells due to various causes like hypoxia, chemicals, microbes or immune injury. It can be coagulative, liquefactive, caseous or fatty. Gangrene occurs when necrosis is accompanied by putrefaction, and can be dry or wet. Infarcts occur when blood supply is cut off to an organ or tissue causing cell death. Oedema and congestion involve excess fluid accumulation in tissues.
1. The document discusses various types of liver and gallbladder pathology including cholangitis, pyogenic cholangitis, primary sclerosing cholangitis, pyogenic liver abscess, amoebic liver abscess, and hydatid disease.
2. Pyogenic liver abscess most commonly results from ascending cholangitis due to obstruction of the biliary tract by gallstones. Amoebic liver abscess is caused by Entamoeba histolytica spreading from the intestines. Hydatid disease involves infection by the larval cyst stage of the tapeworm Echinococcus granulosus.
3. Drug and chemical injury to the liver can occur through direct toxicity, hepatic
Actinomycetes and Nocardia, Bacteria but similar to fungi usually because of its morphological feature of forming a branching filament network, causing Actinomycosis, Actinomycetoma, Farmer's Lung, etc. Demonstrated under microscope by Gram's stain and ZN staining. Cultured on BHI and Thioglycolate broth. Characteristically produce Supher granules. Penicillin is the drug of choice in allergic to penicillin can be replaced by Erythromycin or Tetracycline. In worst cases surgical removal of affected tissue required.
This document summarizes various surgical infections of the skin and subcutaneous tissues. It describes cellulitis as spreading inflammation of subcutaneous tissues, often caused by Streptococcus pyogenes or gram-negative bacteria. Erysipelas is a similar condition caused by S. pyogenes that presents with a rose pink rash and lymphangitis. Abscesses form when infections become localized and contain pus within a cavity lined by granulation tissue. Management of these conditions involves antibiotics, drainage of pus, and dressing wounds. More severe infections like gas gangrene are caused by Clostridium bacteria and cause necrosis of muscle tissue and production of gas within tissues.
An abscess is a collection of pus caused by bacterial infection. It contains dead bacteria, inflammatory cells, and tissue debris surrounded by granulation tissue. Abscesses can be superficial or deep. Common causes are Staphylococcus aureus or Streptococcus pyogenes. Risk factors include impaired immunity, foreign bodies, and tissue injury or ischemia. Abscesses form via bacterial spread or hematogenous/lymphatic dissemination. Signs include swelling, warmth, and tenderness. Diagnosis involves aspiration or imaging. Management is drainage either open or closed along with antibiotics in some cases. Complications can include recurrence, sepsis, or organ impairment.
The document discusses different types of gangrene: wet gangrene, dry gangrene, and gas gangrene. Wet gangrene occurs when both arterial and venous blood flow are blocked, causing tissue to become infected and rotten. Dry gangrene typically affects the toes and feet of older patients due to atherosclerosis, resulting in black, mummified tissue. Gas gangrene is caused by Clostridium bacteria that enter through wounds, producing toxins and gas bubbles within tissues causing swelling and a foul odor.
Necrotizing fasciitis is a rare but serious bacterial infection that rapidly destroys skin, fat, and muscle tissue. It begins as pain, swelling, and redness in the area of infection. The bacteria release toxins that kill tissue and the infection spreads quickly. Treatment requires intravenous antibiotics, extensive surgery to remove dead tissue, and sometimes amputation of limbs. Prompt diagnosis and treatment are important to prevent death from shock or organ failure.
This document discusses necrotizing fasciitis and gas gangrene. It defines necrotizing fasciitis as a necrotizing soft tissue infection along fascial planes that can present with disproportionate pain and swelling. Risk factors include diabetes and immunosuppression. Treatment involves broad-spectrum antibiotics and urgent debridement. Gas gangrene is caused by Clostridium bacteria, often after trauma. It presents with pain, swelling and crepitus, and is treated with antibiotics and radical debridement to remove necrotic muscle. Imaging may show gas in tissues. Both conditions require prompt recognition and aggressive treatment to prevent mortality.
Dr. Monika Negi discusses different types of gangrene including dry gangrene, wet gangrene, and gas gangrene. Dry gangrene results from ischemia and causes tissue to become dry and black. Wet gangrene occurs in moist tissues and is caused by blockages leading to bacterial overgrowth and tissue putrefaction. Gas gangrene develops from clostridial bacteria infecting wounds and causing muscle necrosis and gas formation. Treatment for gas gangrene requires urgent surgery, antibiotics like penicillin, and sometimes hyperbaric oxygen or amputation.
This document discusses Streptococcus bacteria, including Streptococcus pyogenes (Group A Strep). Key points:
- S. pyogenes is a Gram-positive coccus that forms chains and produces beta hemolysis on blood agar. It requires enriched media and is a facultative anaerobe.
- Virulence factors include M protein, streptokinase, hyaluronidase, and pyrogenic exotoxins. M protein determines serotype and virulence. Exotoxins cause scarlet fever rash and toxic shock syndrome.
- Diseases include pharyngitis, impetigo, necrotizing fasciitis, rheumatic fever, glomerul
The document provides an overview of diabetic foot, including definitions, classifications, pathogenesis, clinical features, diagnosis, management, and prevention guidelines. Key points include: diabetic foot is a complication of diabetes that can lead to foot ulcers and amputation due to nerve damage and poor circulation; it is classified based on etiology as neuropathic, ischemic, or neuro-ischemic and staged based on clinical condition; management involves metabolic control, mechanical offloading, vascular management, infection treatment, and patient education.
This document provides information about mucormycosis (black fungus infection) including:
- It is caused by mold called mucormycetes that lives in soil and decaying organic matter.
- It can infect the sinuses and brain (rhinocerebral), lungs (pulmonary), gastrointestinal tract, skin (cutaneous), and become disseminated.
- Risk factors include diabetes, steroid use, organ transplant, cancer, and injuries. Symptoms depend on infected area but may include facial swelling, headache, cough, fever, and black lesions. Diagnosis involves tissue biopsy and cultures. Treatment involves antifungal medicines and sometimes surgery.
1. Oral candidiasis is the most common fungal infection of the oral cavity, caused by Candida albicans. It presents as pseudomembranous, erythematous, or chronic hyperplastic lesions.
2. Histoplasmosis, caused by the dimorphic fungus Histoplasma capsulatum, can cause oral ulcers but is usually asymptomatic. It is endemic in certain regions of India.
3. Mucormycosis is a rare infection caused by fungi in the order Mucorales. It mainly affects immunocompromised individuals and can cause rhino-orbital or pulmonary forms. Rhino-orbital mucormycosis commonly involves the
Streptococcus pyogenes was discussed as a cause of serious infections like pharyngitis, scarlet fever, and rheumatic fever. Scarlet fever presents with a sandpaper-like rash and can develop from untreated strep infections. Rheumatic fever is an inflammatory disease that can cause long-term heart damage if strep throat is left untreated. Fournier's gangrene is a serious genital infection that develops rapidly, often starting from a urinary tract infection or injury. It requires prompt treatment with surgery and antibiotics to prevent life-threatening complications like sepsis. Actinomyces are bacteria normally found in the mouth that can cause infections, especially with intrauterine devices.
Similar to Gas gangrene by Dr.AmrithaAnilkumar (20)
STRICTURE URETHRA
CLASSIICATION -I
I: Aetiologically.
2. Congenital.
3. Inflammatory:
Post-gonococcal
is most common
Gonococcal stricture occurs one year after infection.
Retention develops only 10–15 years later.
Rupture of the anterior urethra is usually caused by a fall astride a projecting object. Clinical features include blood in the urethra, a perineal hematoma, and retention of urine. Treatment involves gentle catheterization in the operating room. If catheterization is not possible, open surgical repair of the tear is performed through a perineal incision. Complications can include infection and stricture formation.
RENAL CALCULUS AETIOLOGY
Males- radio-opaque gall stones
Females - Radiolucent gall stones
Diet:Vitamin A deficiency
it causes desquamation of epithelium
which acts as a nidus for stone formation.
Climate:
In hot climate urinary solutes will increase with decrease in colloids,
PARAPHIMOSIS
DEFINITION
Inability to place back (cover) the retracted prepucial skin over the glans is called as paraphimosis.
It causes ring like constriction proximal to the corona and prepuceal skin.
HYPOSPADIAS
DEFINITION
It is the most common congenital malformation of urethra wherein external meatus is situated proximal than normal, over the ventral (under) aspect of the penis.
HYDRONEPHROSIS (HN)
DEFINITION
It is an aseptic dilatation of pelvicalyceal system due to partial or intermittent obstruction to the outflow of urine.
AETIOLOGY
unilateral
bilateral.
EPISPADIAS
Here the urethra opens on the dorsum of the penis, proximal to the glans.
COMMON SITES
abdominopenile junction.
It is associated with a dorsal chordee, ectopia vesicae, urinary incontinence, separated pubic bones.
It is uncommon in females.
This document discusses benign prostate hyperplasia (BPH), including its etiology, pathology, clinical features, diagnosis, and treatment. BPH is a non-cancerous enlargement of the prostate that occurs in older men due to an imbalance of hormones. It causes obstruction of the urethra and symptoms like frequent urination, weak urine stream, and retention. Diagnosis involves exams, urine and blood tests, and imaging of the prostate, kidneys, and bladder. Treatment depends on symptoms and complications but may include catheterization, surgery to remove part of the prostate like TURP, or other procedures to relieve blockage.
Varicocele is dilatation and tortuosity of the veins within the scrotum that drain blood from the testicles. It is more common on the left side where the left testicular vein drains directly into the left renal vein. Varicocele can cause increased temperature in the scrotum and impair sperm production. Treatment involves surgical ligation of the affected veins to repair blood flow and potentially improve fertility.
TESTICULAR TUMOURS
PREVALANCE
99% of testicular tumours are malignant.
Life time prevalence of getting testicular tumour is 0.2%.
Very common in Scandinavia; least common inAfrica andAsia.
4 times common in whites than blacks.
ORCHITIS
AETIOLOGY
It is an inflammation of the testis.
It is commonly associated with inflammation ofthe epididymis. Hence, called as epididymo-orchitis.
Orchitis is due to infection through blood, lymphatics or epididymis.
EPIDIDYMITIS,
CAUSES
Inflammation of epididymis is commonly associated with orchitis— epididymo-orchitis.
Nonspecific
viral like mumps.
Bacterial.
Filarial.
Tuberculosis
PERFORATED PEPTIC ULCER
PERFORATION
DEFINITION
It is the terminology used for perforation of duodenal ulcer or gastric ulcer or stomal ulcer.
Otherwise all clinical features and management are similar.
Perforation is common in duodenal ulcer
Mortality is more in gastric ulcer perforation and perforation in elderly
GASTRIC ULCER
AETIOLOGY
It occurs due to imbalance between protective and damaging factors of gastric mucosa.
Atrophic gastritis
duodenogastric bile reflux
gastric stasis
abnormalities in acid and pepsin secretion.
Acid becomes ulcerogenic even to normal gastric mucosa.
CURLING ULCER
DEFINITION
They are acute ulcers which develop after major burns, presenting as pain in epigastric region, vomiting or haematemesis.
Curling’s ulcer occurs when burn injury is more than 35%.
It is observed in the body and fundus not in antrum and duodenum
Congenital (infantile) hypertrophic pyloric stenosis by Dr.K.AmrithaAnilkumarDr. Amritha Anilkumar
CONGENITAL (INFANTILE) HYPERTROPHIC PYLORIC STENOSIS
DEFINITION
It is hypertrophy of musculature of pyloric antrum, especially the circular muscle fibres, causing primary failure of pylorus to relax.
Duodenum is normal.
CARCINOMA STOMACH
INCIDENCE
‘It is the captain of men of death’.
It is more common in Japan—70 per 1,00,000 population.
It is more common in males 2:1.
Decrease incidence in western world
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
Integrating Ayurveda into Parkinson’s Management: A Holistic ApproachAyurveda ForAll
Explore the benefits of combining Ayurveda with conventional Parkinson's treatments. Learn how a holistic approach can manage symptoms, enhance well-being, and balance body energies. Discover the steps to safely integrate Ayurvedic practices into your Parkinson’s care plan, including expert guidance on diet, herbal remedies, and lifestyle modifications.
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
share - Lions, tigers, AI and health misinformation, oh my!.pptxTina Purnat
• Pitfalls and pivots needed to use AI effectively in public health
• Evidence-based strategies to address health misinformation effectively
• Building trust with communities online and offline
• Equipping health professionals to address questions, concerns and health misinformation
• Assessing risk and mitigating harm from adverse health narratives in communities, health workforce and health system
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Does Over-Masturbation Contribute to Chronic Prostatitis.pptxwalterHu5
In some case, your chronic prostatitis may be related to over-masturbation. Generally, natural medicine Diuretic and Anti-inflammatory Pill can help mee get a cure.
Hiranandani Hospital in Powai, Mumbai, is a premier healthcare institution that has been serving the community with exceptional medical care since its establishment. As a part of the renowned Hiranandani Group, the hospital is committed to delivering world-class healthcare services across a wide range of specialties, including kidney transplantation. With its state-of-the-art facilities, advanced medical technology, and a team of highly skilled healthcare professionals, Hiranandani Hospital has earned a reputation as a trusted name in the healthcare industry. The hospital's patient-centric approach, coupled with its focus on innovation and excellence, ensures that patients receive the highest standard of care in a compassionate and supportive environment.
6. EFFECTSOF TOXINS
• Extensive necrosis
brown or black
anaerobic
• myositis/myonecrosis.
• affects the liver—
foaming liver
• Limbs are commonly
involved
INCUBATIONPERIOD
• Incubationperiod is 1–2
days.
CLINICALFEATURES
• Toxaemia,
• Fever
• Tachycardia
• Pallor
• Foul smelling discharge
(sicklysweaty/decaying
apple odour).
• Khaki brown coloured skin
• Crepitus
• Jaundice
7. CLINICALTYPES
Fulminanttype- causes
• toxaemia,
• renal failure
• Liver failure
• MODS
• ARDS.
Massive type
• fully dark
coloured gas filled
areas.
Group type
• Infectionof one group
of muscles
Single muscle type
• affecting one single
muscle.
Subcutaneous type
• involves only
subcutaneous tissue
COMPLICATION™
• Septicaemia
• Toxaemia
• Renal failure
• Liver failure.
• Circulatoryfailure
• DIC
8. INVESTIGATIONS
• X-ray
• Liver function tests
• Blood urea
• Serumcreatinine
• Total count, PO2, PCO2.
• Robertson’s cooked meat
media is used whichcauses
meat to turn pinkwithsour
smell and acidreaction
• ClostridiumWelchii is
grownin culturemedia &
In the other half part of the
platewhere there is
antitoxinthere is no
opacity—Nagler reaction.
9. TREATMENT
• Antibiotic&
Hyperbaricoxygen is
very useful.
• Amputationlife-saving
procedure—stump
should never be closed
REFERENCE
1. SRB's Manual of Surgery
by SriramBhatM
2. A Manual on Clinical
Surgeryby Das
3. A Concise textbookof
Surgeryby Das