Chapter 7 focuses on estimating parameters and determining sample sizes, detailing how to calculate confidence intervals for population proportions and means, both with known and unknown standard deviations. It includes methods for estimating population means, the concept of margin of error, and the interpretation of results, using examples such as the effectiveness of garlic on cholesterol levels and the average depth of a river. The chapter emphasizes the importance of sample size determination for accurate estimates and includes discussions on the t-distribution and z-distribution based on sample data characteristics.