Erythropoietin is a hormone produced by the kidney that stimulates red bone marrow to produce red blood cells, which transport oxygen throughout the body. It prevents anemia and hypoxia. Epo drugs are used to treat chemotherapy-induced anemia and anemia associated with chronic kidney disease, cancer, and HIV. Common forms of Epo include epoetin alfa, beta, omega, and delta, and derbepoetin alfa. Dosing depends on the condition being treated, with doses adjusted based on hemoglobin levels. Epo must be stored properly and not exposed to light or freezing temperatures.

1. SHREE MEDICAL AND TECHNICAL COLLEGE
BHARATPUR -12, GONDRANG
Presentation on Erythropoietin
PRESENTED BY:
SANJAY KUMAR YADAV
ROLL NO.: 22 (5th sem.)1/18/2020 0sanjay k. yadav

2. INTRODUCTION
Erythropoietin is a Hormone.
Also called Epo.
Produced by kidney.
By which stimulation of red-bone marrow to
produce erythrocytes ( RBCs ).
RBCs transport oxygen throughout the body.
Finally , prevents from the anemia, hypoxia etc.
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3. REGULATION
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4. DRUGS
Epo drugs are used for treatment of
chemotherapy-induced anemia,
Anemia is common side effect occuring due to
chemotheraphy of ESRD, cancer and HIV.
Forms of Epo such as epoetin alfa, epoetin beta,
epoetin omega, epoetin delta, derbepoetin alfa.
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5. DOSES
 ANEMIA ASSOCIATED WITH CKD:
----Adult: Initial dose: 50 to 100 units/kg IV or subcutaneously 3
times a week
----Pediatric (1 Month to 16 Years): Initial dose: 50 units/kg IV or
subcutaneously 3 times a week
 Conditions:
----If hemoglobin increases by more than 1 g/dL in 2 weeks, reduce dose
by 25%
----If hemoglobin has not increased by more than 1 g/dL after 4 weeks
of therapy, increase dose by 25%.
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6. Storage conditions: -Protect from light.
-Store at 2 to 8C. - Do not freeze.
Other conditions:
-Do not dilute.
-Do not shake.
-Allow this drug to reach room temperature before
injecting.
- Do not use preservative-free vials.
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