The document discusses the erythrocyte sedimentation rate (ESR), a common medical test. It defines ESR as the rate at which erythrocytes settle in an hour. There are several methods to measure ESR, including the Westergren and Wintrobe methods. The Westergren method uses a specially designed tube to measure settlement in millimeters after one hour. ESR can be increased in infections, inflammation, and cancers or decreased in anemias and other blood abnormalities. Normal ranges are 0-10 mm for men and 0-20 mm for women and children.
Erythrocyte Sedimentation Rate (ESR), a lecture for medical lab technicians at Baquba Technical Institute, Middle Technical University. All theoretical and practical notes about the test.
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An immature red blood cell without a nucleus, having a granular or reticulated appearance when suitably stained.
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They are originally seen at the site of their formation i.e. bone marrow. They take 2-3 (lays for maturation only about 1-2% of circulating RBCs are Reticulocytes.
This presentation is focused on diagnostic utility of Red blood cell indices which will be very useful for undergraduate and postgraduate of medical field.
An immature red blood cell without a nucleus, having a granular or reticulated appearance when suitably stained.
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They are originally seen at the site of their formation i.e. bone marrow. They take 2-3 (lays for maturation only about 1-2% of circulating RBCs are Reticulocytes.
This presentation is focused on diagnostic utility of Red blood cell indices which will be very useful for undergraduate and postgraduate of medical field.
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
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2. • - Definition
• -Methods
• Principle
• Normal ranges
• Procedure
• Advantages
• Increased and decreased conditions
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3. Definition
• The rate at which erythrocytes settle down at
the bottom of the tube at 1st one hour is
regarded as erythrocyte sedimentation rate.
• ESR is a commonly used nonspecific test in
routine clinical practice
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5. DETERMINATION OF ESR BY
(WESTERGEN’S METHOD)
• Method : Westergren's Method
• It has been proved as the international
reference method.
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6. Westergren's tube Description
• It is a straight glass tube
30cm in length
• and 2.5mm in a diameter
with a capacity of 1ml.
• A scale graduated in mm
from (0-200mm).
• Specially made racks with
adjustable leveling screws
are available for holding the
sedimentation tube in
vertical position.
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7. Normal Range / Biological Reference Range :
– Male : 0 – 10 mm after 1hour
– Female : 0 – 20mm after 1 hour
– Children : 0- 10mm after 1 hour
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8. PRINCIPLE
• When a anticoagulated blood is placed in a
vertical tube and is allowed to stand, RBCs
settle towards the bottom of the tube. The
speed of sedimentation of red cells in plasma
over a period of 1 hour is measured by the
length of the sedimented RBC column and is
expressed in milimeters.
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9. • RBCs have net negative charge on their
surface and tend to repeal each other. The
repulsive forces are partially or totally
counteracted if there is an increase in the
positively charged plasma proteins
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10. Factors affecting ESR
• Plasma factors : Eg, Fibrinogen , Globulins.
• Red Cell factors :
• A. Number- Eg Anaemia Polycythemia
• B.Size
• C.Rouleaux formation
• D.abnormal or irregular shape
• Technical factors : ESR tube must be kept in
vertical, other wise it results inaccurate ESR
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14. Specimen Required
• 1.6 ml of blood + 0.4 ml of 3.8% sodium
citrate
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15. Specimen collection & Storage
• Test should be set up within 2 hrs after
collection
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16. procedure
• 1.Fill the Westergren's tube exactly up to Zero mark by
means of rubber bulb ( avoid air bubbles).
• 2. Place the tube upright in the stand. It should fit evenly
into the groove of the stand
• 3.Note the time. Allow the tube to stand for exactly one
hour
• 4.Exactly after one hour, note the level to which the red cell
column has fallen.
• 5.Report the result in terms of mm/after 1 hour.
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17. Phases of ESR
• Phase of rouleaux formation- 10 min
• Phase of sinking - 40 min
• Phase of packing - 10 min
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19. DETERMINATION OF ESR BY
WINTROBE METHOD
• Wintrobe’s Method: ESR is estimated on
anticoagulated blood in a Haematocrit tube
which is also used for PCV estimation.
• Advantage of this method is that same tube is
used for PCV and ESR.
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20. Normal range:
• 0-9 mm fall at 1hr in males
• 0-20 mm fall at 1 hr in females.
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21. Requirements
• Wintrobes tube
• Wintrobes tube stand
• Pasteur pipette or 2 ML syringe with needle
• Timer or watch
• Sodium citrate blood sample (3.8%)
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22. Procedure
• 1. Mix the blood carefully
• 2.Fill the Wintrobes tube zero mark by using a
Pasteur pipette or by using a syringe
• 3.place the tube in exact vertical position in the
stand . Set the timer for one hour
• 4.At the end of one hour note the level of
erythrocyte count in terms of mm after 1 hour
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