The principles of vascular repair with sutures were established in the first decade of the 20th century by Alexis Carrel, who in 1912 was awarded the Nobel Prize for medicine for his work .Since then, technical refinements of suture materials have made possible surgical reconstruction of most arteries from the root of the aorta to microvascular anastomosis or repair of the smallest vessels, e.g., digital arteries or those on the surface of the brain.
Principles of angioplasty -Endovascular Management of Peripheral Vascular Dis...Saurabh Joshi
This presentation covers the principles of peripheral angioplasty with and explanation of the TASC stratification and selection of appropriate management according to current guidelines. Endovascular management of peripheral vascular disease.
Retrograde approach step-by-step
Kambis Mashayekhi, Bad Krozingen, Germany
11th Experts Live CTO
The annual Euro CTO meeting
September 13th –14th, 2019 - Berlin, Germany
The principles of vascular repair with sutures were established in the first decade of the 20th century by Alexis Carrel, who in 1912 was awarded the Nobel Prize for medicine for his work .Since then, technical refinements of suture materials have made possible surgical reconstruction of most arteries from the root of the aorta to microvascular anastomosis or repair of the smallest vessels, e.g., digital arteries or those on the surface of the brain.
Principles of angioplasty -Endovascular Management of Peripheral Vascular Dis...Saurabh Joshi
This presentation covers the principles of peripheral angioplasty with and explanation of the TASC stratification and selection of appropriate management according to current guidelines. Endovascular management of peripheral vascular disease.
Retrograde approach step-by-step
Kambis Mashayekhi, Bad Krozingen, Germany
11th Experts Live CTO
The annual Euro CTO meeting
September 13th –14th, 2019 - Berlin, Germany
my aortic surgery presentation in Solo as an introduction for general practitioner and cardiology resident
Cover the basic diagram of surgical procedures of aorta.
definitely not for surgeon.
in endo era. aortic is one of the industrial driven medical proedure & one of the most expensive. Its morbidity are quoet acceptable, but......... surgeon if the best deal behind this awsome techno
Peripheral Angioplasty / Endovascular Management of PVD - PrinciplesSaurabh Joshi
This presentation covers the principles of peripheral angioplasty with and explanation of the TASC stratification and selection of appropriate management according to current guidelines. Endovascular management of peripheral vascular disease.
thoracic aortic injuries are very rare, this presentation will give a brief idea regarding the presentation of Thoracic aortic injury and its management
my aortic surgery presentation in Solo as an introduction for general practitioner and cardiology resident
Cover the basic diagram of surgical procedures of aorta.
definitely not for surgeon.
in endo era. aortic is one of the industrial driven medical proedure & one of the most expensive. Its morbidity are quoet acceptable, but......... surgeon if the best deal behind this awsome techno
Peripheral Angioplasty / Endovascular Management of PVD - PrinciplesSaurabh Joshi
This presentation covers the principles of peripheral angioplasty with and explanation of the TASC stratification and selection of appropriate management according to current guidelines. Endovascular management of peripheral vascular disease.
thoracic aortic injuries are very rare, this presentation will give a brief idea regarding the presentation of Thoracic aortic injury and its management
Stroke thrombolysis Dr Sanjay Jaiswal,consultant nerologist,Jaiswal Hospital ...Sanjay Jaiswal
We are presenting our personal experience regarding thrombolytic therepy in ac ischaemic stroke patients at jaiswal hospital and neuro institute ,kota,Rajasthan,INDIA
Intracoronary Imaging – when to use, how to use and how to interpret the imagesEuro CTO Club
Intracoronary Imaging – when to use, how to use and how to
interpret the images
Javier Escaned, Spain
The Experts “Live” Workshop 2017
Saturday, September 16th, 2017
Fundación EPIC _ Sedación anestesia general y eco de guiadoFundacion EPIC
Presentación de la ponencia "Sedación anestesia general y eco de guiado" por el Doctor Moris de la Tasa en los Diálogos EPIC_Retos Clínicos en Válvulas Transcatéter/ Clinical Challenges in TAVR today, el 10 de Mayo de 2018 en Barcelona (España)
Complication on avf play significant number of hospitalization & morbidity. Despite fistula first campaign are still beneficial for most patient, gathering knowlege to prevent complication are important.
simple word for future doctor. writing & drawing in pure white paper is always fun & feels like nothing to loose even if we knew that it will last almost forever
bentall, and 'old' procedures that still valid until present. Bail out for valve sparring & the patology of indonesian most present were best in this procedures
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
The Gram stain is a fundamental technique in microbiology used to classify bacteria based on their cell wall structure. It provides a quick and simple method to distinguish between Gram-positive and Gram-negative bacteria, which have different susceptibilities to antibiotics
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Best Ayurvedic medicine for Gas and IndigestionSwastikAyurveda
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
2. WHY SO IMPORTANT?
• PAD is often present in patients with
established CAD
• PAD may be the first and/or only
manifestation of atherothrombosis in
several pts
• Peripheral complications during PCI
or other cardiac interventions are
not rare
4. Before the Battle
• Be prepared (for the worst)
• Be carefull (misleading journals &
articles)
• Be well trained surgeon
5. Before the Battle
• Endovascular setting is Surgical setting
• Blood – OR team – Fasting – Consent –
Surgical field preparation.
• Radiation knowledge
• Access problem = BIG problems
9. Garcia et al, Catheter Cardiovasc Interv 2009;74:27-36
COMMON ACCESS SITES FORCOMMON ACCESS SITES FOR
PERIPHERAL=FOR CORONARYPERIPHERAL=FOR CORONARY
10. Garcia et al, Catheter Cardiovasc Interv 2009;74:27-36
LESS COMMON ACCESS SITESLESS COMMON ACCESS SITES
FOR PERIPHERAL≠FORFOR PERIPHERAL≠FOR
CORONARYCORONARY
11. Vascular Access sites
Retrograde Common Femoral Artery Access
•Common access site used for
peripheral diagnostic angiography
and intervention
•Prevent injury to the less diseased
extremity
12. Vascular access sites
•Contralateral femoral retrograde
access :
•Internal iliac stenoses are best
treated from a contralateral approach
•SFA,PFA- lesions located within the
CFA/involve SFA/PFA ostium –
•Proximity to arterial puncture site,
Bifurcation anatomy of CFA
•Also allows treatment B/L disease
with a single arterial puncture
13.
14. Vascular Access site
Antegrade Common Femoral Artery Access:
•Required for infrainguinal proced
•Approx 3cm CFA lies betw
ligament & FA bifurcation
•Inorder to access CFA, skin entry-
prox to ing ligm
•Access too close to F bifurc –
inadeq working room to
selectively cath SFA
18. Modified TASC Morphological Classification of
Femoral-Popliteal Lesions
•A. Endovascular treatment of choice:
• Single <3-cm stenosis (unilateral/bilateral)
•B. Endovascular more often used:
• Single 3- to 5-cm stenosis
• Heavily calcified stenoses ≤3 cm
• Multiple lesions each ≤3 cm (stenoses or occlusions)
• Single or multiple lesions, in the absence of continuous tibial
runoff, to improve inflow for infrageniculate bypass
•C. Endovascular if possible:
• Single stenosis or occlusion 5 to 10 cm
• Multiple stenoses or occlusion, each 3 to 5 cm
•D. Surgery preferred, endovascular considered on case-by-case basis:
• Complete occlusion of CFA or SFA or popliteal and proximal
crural arteries
Norgren L, Hiatt WR, Dormandy JA, Nehler MR, Harris KA, Fowkes FG. Inter-Society Consensus for the
Management of Peripheral Arterial Disease (TASC II). J Vasc Surg. 2007; 45: S5–S67
SFA and Popliteal Artery Disease
24. TAKE HOME MESSAGES
• Peripheral intervention skills must be
mastered by all endovascular surgeon for
bail-out indications
• Motivated endovascular surgeons can
pursue further improvements by focusing
on district-specific indications, anatomy,
and devices
• Team work
emonstrated no difference at 1 year for angioplasty or surgery
There was no difference in limb salvage or patient survival at 5 years.. But patency etc
Darah daftar puasa konsul inform consent sio cukur… psiapa op lengkap dg graft
Akses.. Open or puncture
DM, renal failure, koagulopathy, tua(CV, kalsifikasi)
Complication.. To outcome
Medical therapy, intervention, and surgery have been compared in several trials in symptomatic patients with femoral-popliteal disease. A meta-analysis that compared PTA with exercise therapy in patients with intermittent claudication reported similar quality-of-life outcomes at 3 and 6 months but also found that functional capacity (ABI) improved more with endovascular therapy than with exercise.49 Cost-effectiveness and quality-of-life outcomes favor the performance of percutaneous therapy whenever feasible as a more effective treatment than exercise alone.50 A matched-cohort study of 526 patients with intermittent claudication found significant advantages for a revascularization strategy (surgery or PTA) compared with medical therapy.51 Revascularization was more effective than medical therapy for improvement in physical function, bodily pain, and walking distance. Patients with the greatest improvement in their ABI results had the best clinical improvement, which indicates that the degree of revascularization was related to a successful outcome. If the 5-year patency rate is estimated to be ≥30%, the authors concluded that percutaneous therapies would be superior to surgery.52
Clinical success in patients with SFA lesions depends on a durable, long-lasting procedure. Multiple clinical trials in small numbers of patients had previously failed to show any advantage for stents compared with PTA (Table 4).1 A meta-analysis did, however, demonstrate better patency at 3 years for stents than for PTA in the most severely affected patients, those with occlusions and CLI.53 A recent randomized controlled trial demonstrated a better outcome for primary SFA stent placement than a strategy of provisional stent placement. Not only was restenosis significantly lower in the stent group at 6 and 12 months, but there was also better functional improvement (ABI) and walking distance in the primary stent group (Figure 7).54 An interesting observation was that stent fractures, which have been associated with restenosis in SFA lesions,55 were only reported in 2% of the stents (Dynalink/Absolute, Abbott Vascular) used in this trial. There are differences regarding stent fracture among SFA stents that are presumably related to their composition and architecture. A recently published series found fracture rates of 28% for the SMART stent (Cordis), 19% for the Wallstent (Boston Scientific), and 2% for the Dynalink/Absolute stent (Abbott Vascular).56 The issue of stent fracture is a complex one, with attendant restenosis being greater in the fracture territory and the length of lesion/presence of multiple overlapping stents also being an apparent contributing factor