An autopsy (post-mortem examination, obduction, necropsy, or autopsia cadaverum) is a surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause, mode and manner of death or to evaluate any disease or injury that may be present for research or educational purposes.
in this topic of autopsy and embalming, various topics like definition of autopsy and embalming, purposes, steps, procedure, role of nurse is discussed.
Histopathology is examination of tissues for presence or absence of changes in their structure due to disease processes. We go through various steps in the process of converting gross sample to microscopic slides.
An autopsy (post-mortem examination, obduction, necropsy, or autopsia cadaverum) is a surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause, mode and manner of death or to evaluate any disease or injury that may be present for research or educational purposes.
in this topic of autopsy and embalming, various topics like definition of autopsy and embalming, purposes, steps, procedure, role of nurse is discussed.
Histopathology is examination of tissues for presence or absence of changes in their structure due to disease processes. We go through various steps in the process of converting gross sample to microscopic slides.
The second module out of four. Part of a research study for my thesis work called A Good Death. The work was is an ongoing project that begun as part of my MFA studies at Parsons the New School for Design.
Renal Replacement Therapy for Kidney diseasesachintutor
Renal replacement therapy is therapy that replaces the normal blood-filtering function of the kidneys. It is used when the kidneys are not working well, which is called kidney failure and includes acute kidney injury and chronic kidney disease.
It is the removal of solutes and water from body across a semipermeable membrane (dialyzer)
care during and after the dialysis is very important to prevent the entry of pathogens in to the body.
Psychiatry– it deals with study, diagnosis, treatment and prevention of mental illness.
Forensic psychiatry- application of knowledge of psychiatry
These are the person who are unable to cope with the ordinary social circumstance
Sexual assault related laws and examination of survivourDr. FAIZ AHMAD
Sexual offences
are criminal forms of human sexual behavior
A
sex offender is one who commits a sexual offence
CLASSIFICATION
Sexual offences may be classified as below
(I) Natural sexual offences
Offences involving natural penile
vaginal penetration
A)
Violent Done without consent e.g. rape
B)
Non violent done with consent e.g. incest , adultery
MEDICAL PRACTITIONER
means an individual who practices the art of
allopathic system of modern medicine .
REGISTERED
MEDICAL PRACTITIONER ( means Medical
Practitioner whose name appears i n the official register kept for the purpose
in accordance with the law of the land to which one belongs
Article 3 of Universal Declaration of Human Rights states “everyone has
the right to life, liberty and security of a person”
Article 21 of the Constitution of India guarantees no person shall be
deprived of his life or personal liberty except according to the procedure
established by law”
Thus right to life, liberty and security of a person are recognized as a
fundamental right by the Universal Declaration of Human Right (article
3 of 1948 and article 21 of the Indian Constitution
The transplantation of human organs and tissue act 1994(TOHOTA)Dr. FAIZ AHMAD
This Act was enacted for the
Regulation of removal , storage and transplantation of human organs
for therapeutic purposes only
F or the prevention of commercial dealings in human organs.
Justifiable abortion (therapeutic abortion)Dr. FAIZ AHMAD
It is also called as therapeutic abortion or legal abortion
In 1970 the World Medical Association WMA) adopted a resolution
on therapeutic abortion, known as Declaration of Oslo
It is performed either in accordance with the legal provisions under
the Medical Termination of Pregnancy (MTP Act 1971 (i e legal
abortion) or caused in good faith to save the life of the pregnant
woman
Sexual violence occurs throughout the world Available data suggest
that in some countries nearly one in four women may experience
sexual violence by an intimate partner and up to one third of
adolescent girls report their first sexual experience as being forced
Sexual violence has a profound impact on physical and mental health
As well as causing physical injury, it is associated with an increased
risk of a range of sexual and reproductive health problems, with both
immediate and long term consequences
Derived from GK word daktylose-finger ,graphein- to write
Method of identification based on unique epidermal ridge pattern on the tips of fingers.
Syn-Fingerprinting, Dermatoglyphics, Galton system of identification
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
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Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
2. Preservation of Dead Body
Artificially
Freezing
Embalming
Texidermy
Ancient egyptian
method(mummification)
Formalin preservation
Paraffin impregnation
Plastination
Naturally
• At very low temperature.
• At very high temperature.
• Shallow moist clay soiled
grave,or submerged in water.
• In water or soil containing
antiseptic substance
like,,arsenic,lime etc.
3. Definition: It is a process of preservation of
dead body by treating it with antiseptic and
preservatives to prevent putrifection.
By this process,
1. Protein are coagulated
2. Tissues are fixed
3. Organs are bleached and hardened
4. Blood is coagulated and transformed into a pinkish brown
mass
EMBALMING
4. • Embalming produce a chemical stiffening similar to rigor mortis
but normal rigor does not develop.
• Rigidity in case of embalming is permanent.
• To get desired effect- embalming to be done within 6 hrs of death.
• If done several hrs of death,the body will show mixture of bacterial
decomposition and mummification and will disintigrate in few
months.
5. Embalming is done in:
• Medical College to preserve dead body for the purpose of
education and dissection.
• When the dead body has to be taken from one country to
other or in same state for last rituals.
Embalming is done by injecting embalming fluid in the
body.
9. • Sodium borate and sodium citrate should be dissolve in hot
water and allow to cool.
• Add rest of the component and dilute with water to make up
ten liters.
• Allow to stand for few hours and filter.
• A dead body of 70 kg weight requires 10 liters of embalming
fluid of which 10% will be lost through various drain and
purging.
10. For cavity embalming the fluid having the
following composition
1. Formalin _ 60%
2. Methenol _25%
3. Phenol _ 10%
4. Sodium lauryl sulphate _ 1%
5. Mercuric chloride _1%
6. Eucalyptus oil _1%
11. Types of embalming
1. Arterial embalming
2. Cavity embalming
3. Hypodermic embalming
4. Surface embalming
5. Embalminf of autopsied body
6. Embalming of AIDS body
12. Arterial embalming
• Place body supine on table.
• Remove clothing and surgical dressing if any and the body
washed withan antiseptic soap and warm water.
• Rigor mortis,if present should be broken by
bending,massaging,rotating the head etc.
• The nostrils are cleaned and plugged with a wad of cotton
soaked in arterial solution.
13. Arterial Embalming Conti..
• The cheek may be filled out with cotton soaked in arterial
solution.
• The mouth and eyelid shoud be closed.
• If eyebal is sunken arterial solution should be injected into the
orbit and eyeball.
• The head should be elevated 8to10cm and placed on head rest
and feet raised to facilitate drainage.
• Anal orifice and vagina plugged similarly.
15. Choice of vessels
• The nearer the vessel to the heart ,the better the
result specially for drainage.
• Single point injection leave the patches of area
unfixed by embalming fluid.
• Multiple site injection used in,,traumatic
death,autopsised case and postmortem mutilation.
16. • Six point injection involve , R/L common
carotid A for head and neck, R/L axillary A for
upper limb ,and R/L femoral A for lower limb.
• On completion the vessel should be ligated to
prevent leakage of embalming fluid.
17. • Each side of face injected separately to prevent
distortion of face due to over injection
• After injection of one artery it should be
ligated before injecting to other artery,
• All drainage point should be ligated after
completion to prevent leak.
18. Instrument used for injecting the
embalming fluid
a) Hand/ foot pump
b) Stirrup pump
c) Bulb syringe:
• This is a manual pump similar to Higginson's syringe.
• Bulb type rubber syringe and rubber tubing at either end.
• Valves,allow suction on one side and ejection on other side
d. Gravity injector:
• It is the simplest,safest,slowest of the injection method.
• Gravity bottle or percolator should hold 10 lit of fluid and raised above body .
• A rise of 1 m gives a fluid pressure of 0.6kg/sq.cm and 2m about 1kg/sq.cm
• Take longer time and distribution of fluid is uneven.
21. e)Motorised injectors:
• Fluid from injection tank is forced into the vascular
system using air from a compression tank.
• Prassure and flow rate are controled by device
• 10 litres of arterial solution injected within 30 min.
• Injection prassure is about 2kg/sq.cm
23. Method of injection
1.Continuous injection and drainage
• The arterial injection is given continuously
• Vein tube kept open throughout injection
• Embalming time much shorter
• Venous drainage and tissue saturation is poor
• Least satisfactory
24. 2. Continuous injection with disrupted drainage
• The injection is continuous with vein tube closed.
• The blood in the vein build up a resistance for
arterial flow which help in better diffusion of fluid.
• Thick blood is discharged when drain tube is
opened.
• Bettrer than continuous discharge and drainage.
25. 3.Alternate injection and drainage
• The arterial fluid is injected for some time with drain tube
closed.
• The injection is stopped when superficial veins swell, and
drain is opened.
• When the flow of blood from the drain tube stop, it is
closed and injection started.
• This process repeated several time.
26. 4. Discontinuous injection and drainage:
• This consist of repeated arterial injection of small quantities at
two hrs interval.
• The total quantiti of injection fluid is in exces of ordinary
injection done at a time.
• Injection is continued for three or four time.
• The venous drain tube which is closed is opened a little before
and open a little after starting another dose of injection.
• This is the best method.
27. b)cavity embalming(closed cavity
treatment)
• Cavity treatment should be done after half to
one hrs,Which allow for the hardening of the
viscera and facilitate piercing of the gut.
• A motorised aspirator if available is better.
• A 30cm long trocar is inserted into the abdomen
throug small incision 5to6cm above umbilicus
in mid line.
29. • The trocar is first directed upward, backward and
to the left to pierce and aspirate the stomach.
• Then trocar is slightly withdrawn and pushed up
toward right to pierce right side of heart.
• Next the right and left pleural sacs are reached
by piercing diaphragm and aspirated.
30. • Next several puncture are made in small
intestine , caecum , colon to suck out content.
• The urinary bladder, sigmoid colon and rectum
should be aspirated.
• One liter of cavity fluid should be injected
distributing it evenly throughout the cavity.
31. c)Hypodermic embalming
• Suitable for embalming isolated limbs,body parts
followimg bomb blast,air crush,railway injuries
• Embalming fluid injected subcutaneously.
d) Surface embalming:
• Suitable for burn injury cases.
• Whole body is packed with cotton soaked in
embalming fluid.
32. e)Embalming of autopsied body:
• Before stitching up ,thoraco-abdominal and cranial
cavity is sponged with embalming fluid
• Then viscera properly treated with embalming
fluid,covering and packing with embalming fluid
soaked cotton
• Placed within the body cavity and stitched up.
• If body is already stitched up,removed and re -stitched.
33. f)Embalming of AIDS bodies:
• Concentration of arterial and cavity
embalming fluid is increased.
• Recomended precaution to be taken during
handling the body.
34. Legal aspects of practice of
embalming
• Proper identification of body by near relative is done
before procedure.
• Concent for the procedure should be obtained.
• No objection certificate from police should be obtained.
• Death certificate should be referred before embalming.
• In case of foreigner, Embassy clearance should be
obtained in addition.
35. • In medicolegal cases, it should be done after autopsy.
• Death certificate/P.M report should be accompanied
with the dead body.
• On completion of embalming,embalmer/competent
authority should issue certificate(for local transport
3copies ,and for international transport 5 copies.
• In case of embalming of dead body who suffered from
noticeable disease(cholera,rabis,plague,tetanus
,HepB,AIDS,TB etc)concern authority is informed.
36. MEDICOLEGAL ASPECTS OF
EMBALMING
1. Embalming should never be allowed before
autopsy, it may induce artifact and poses
difficultu in interpreting the finding.
2. Embalming provides chemical stiffening similar
to rigor mortis, so difficulty arise in estimating
time since death.
3. Embalming alter the appearence of body so
interpretation of injuries become difficult.
37. 4.Embalming destroys cyanide,alcohol,opiates, carbon
monoxide thus toxicological analysis become useless or
difficult.
5.Embalming kills bacteria so bacteriologic evaluation become
useless.
6. Due to embalming blood group cannot be made out.
7.Detection of thrombus or embolism are not possible.
8.The dimentions of wounds may be modified by the embalmer
or new wounds may be produced due to use of trocher.