1) Burns are injuries caused by heat or chemicals and can be classified based on depth and surface area affected.
2) First degree burns involve only the epidermis, second degree extend deeper to the dermis, and third degree destroy the entire skin.
3) Complications can include shock, infection, organ failure and death in severe cases.
4) Treatment depends on severity but generally involves cooling the burn, pain relief, wound care, fluid resuscitation and antibiotics to prevent infection.
FORENSIC MEDICINE BOOKS OF
REDDY
GOUTAM BISWAS
MAGENDRAN
OTHERS
TOPICS :-
COLD INJURY
HEAT INJURY
BURN INJURY
SCALDS
ELECTROCUTION
LIGHTENING INJURY
THIS IS ONE OF MY BEST AND FAVORITE PRESENTATIONS. IT WILL SURELY HELP YOU A LOT DURING YOUR EXAMS (PROF/OTHERS). IF YOU FIND IT HELPFUL THEN LIKE IT. MY EMAIL ID IS GIVEN ON THE 2ND PAGE OF THIS PRESENTATION, IF YOU WANT PRESENTATIONS ON OTHER TOPICS (ANY MEDICAL SUBJECTS) THEN MAIL ME. I WILL WORK ON IT LOT AND WILL BE TRYING TO SHARE WITH YOU GUYS...
THANK YOU
An account of strangulation, its types, mechanism, causes of death, post-mortom signs of death due to strangulation, fracture of thyroid cartilage and hyoid bone, medico-legal aspects of strangulation
FORENSIC MEDICINE BOOKS OF
REDDY
GOUTAM BISWAS
MAGENDRAN
OTHERS
TOPICS :-
COLD INJURY
HEAT INJURY
BURN INJURY
SCALDS
ELECTROCUTION
LIGHTENING INJURY
THIS IS ONE OF MY BEST AND FAVORITE PRESENTATIONS. IT WILL SURELY HELP YOU A LOT DURING YOUR EXAMS (PROF/OTHERS). IF YOU FIND IT HELPFUL THEN LIKE IT. MY EMAIL ID IS GIVEN ON THE 2ND PAGE OF THIS PRESENTATION, IF YOU WANT PRESENTATIONS ON OTHER TOPICS (ANY MEDICAL SUBJECTS) THEN MAIL ME. I WILL WORK ON IT LOT AND WILL BE TRYING TO SHARE WITH YOU GUYS...
THANK YOU
An account of strangulation, its types, mechanism, causes of death, post-mortom signs of death due to strangulation, fracture of thyroid cartilage and hyoid bone, medico-legal aspects of strangulation
Forensic science PowerPoint presentation on Injury and it's medico-legal importance.
The slide is made for medical students. Mainly for BAMS students. It covers maximum points.
The slide is full of example with pictures which make it easy to understand the concept. It contains post-mortem findings as well as medico-legal importance of the each type of injury.
Drowning is an inhalation of liquid in respiratory tract leading to suffocation and death. it can be wet or dry drowning depending upon the water entering in trachea. some times water touching the larynx leading to spasm and complete closure leading to dry drowning.
Asphyxia which means "Pulselessness" and is cause due to absence of oxygen amount in a body. The death cause by asphyxia is known as asphyxial deaths. They are Hanging, Strangulation, Suffocation and Drowning.
infanticide are quite common in India because of illiteracy as well as the female child unwanted . Now a days female sexual assault and murder is getting common in north Indian society
Forensic science PowerPoint presentation on Injury and it's medico-legal importance.
The slide is made for medical students. Mainly for BAMS students. It covers maximum points.
The slide is full of example with pictures which make it easy to understand the concept. It contains post-mortem findings as well as medico-legal importance of the each type of injury.
Drowning is an inhalation of liquid in respiratory tract leading to suffocation and death. it can be wet or dry drowning depending upon the water entering in trachea. some times water touching the larynx leading to spasm and complete closure leading to dry drowning.
Asphyxia which means "Pulselessness" and is cause due to absence of oxygen amount in a body. The death cause by asphyxia is known as asphyxial deaths. They are Hanging, Strangulation, Suffocation and Drowning.
infanticide are quite common in India because of illiteracy as well as the female child unwanted . Now a days female sexual assault and murder is getting common in north Indian society
A burn is a type of injury to skin, or other tissues, caused by heat, cold, electricity, chemicals, friction, or radiation. Most burns are due to heat from hot liquids, solids, or fire. While rates are similar for males and females the underlying causes often differ.
This presentation will help you to find answers for all the questions related to definition, types, causes, treatment, management and nursing care to burns patient.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
2. INTRODUCTION:-
• Heat is form of energy which when transferred to body produces
thermal injury in the form scalds &burns.
• Scalds :-
produced due to application of moist heat to body. The Boiling
liquids that can scald include water ,milk, oil etc.
• Burns:- produced due to application of dry heat.
min. temp for producing burn is 440 c for exposure of about 5 to
6 hours while 65 0 c for 2 seconds is sufficient to cause burns.
3. DEFINITION:-
•A burn is an injury which is
caused by application of heat /
chemical substance to external
or internal surface of body
7. DUPUYTREN’S CLASSIFICATION
• Classified depending on severity of burns.
• First degree- erythema then desquamation of superficial layer of
epidermis.
• Second degree- blister formation
• Third degree- destruction of epidermis
• Fourth degree- destruction of whole thickness of skin
• Fifth degree- destruction of muscles
• Sixth degree- destruction of bone,nerve trunks etc.
8. In practical situations Dupuytren’s
classification is limited to three degrees.
First degree : Epidermal burns
In this the lesion is
confined to the epidermis. There may be
Blistering without lose of epidermis . If the
blister bursts reddened base is seen.
9. • Second degree : Dermoepidermal burns
• There is a destruction of full thickness of the
skin.
• The epidermis is coagulated or charred.
• There is a central zone of necrotic tissue
surrounded by first degree
• Scarring is in evitable & is due to formation
contractures, there is disfiguration.
10. Third degree burns : Deep burns
• There is a destruction of deeper tissues
below the skin surface.
• The skin is totally destroyed, though in
some deep burns, islands of intact
dermis may be found.
• Damage to subcutaneous fat & loss of
muscle, bone etc., is seen.
11. CLASSIFICATION BASED ON
SURFACE AREA:-
• The rule of nines
• Body part effected % of burns
• Head & neck 9
• Rt upper limb 9
• Lt upper limb 9
• Rt lower limb 18
• Lt lower limb 18
• Front of trunk 18
• Back of trunk 18
• Genitals 1
12. • Burn injury is more severe if heat applied is of great intensity
& exposure to heat is for long time.
• It also depends on area involved. Burns to face, genital,
lower part of abdomen is more dangerous.
• Infants & elderly people are more susceptible to
complications of burns.
13. COMPLICATIONS OF BURNS:-
Heat haematoma:-
Haematoma may form in extra dural
space between skull & dura mater when
cranium is exposed to severe heat.
Heat rupture:-
Heated skin contracts & splits .It is usually
seen on elbows, knees & head
14. Heat rigor:-
It is observed mainly in muscles. There is
generalized flexion of trunk , arms &legs
.upper limbs held out with fingers curled
inwards assembling attitude of boxer
{pugilist} .This is refers as pugilistic attitude.
Heat fracture:-
Due to intense heat bones get fractured
especially cranial vaults & limb bones.
15. MANAGEMENT OF BURNS
• Mild or moderately severe-
First aid-
• Cool area with running water for 20 min.
• For chemical and eye burns, irrigate with copious volumes of water.
Pain relief-
• Paracetamol,codeine,morphine
• Airway and breathing should be ensured
• Circulation- signs for circulatory obstruction should be checked.
16. • Severe
Airway and breathing-
• In case of airway burn and lung injury,arrange intubation before
airway swelling occurs.
Circulation-
• If > 10% body surface involved,commence fluid resuscitation.
• If > 10% deep partial thickness or full thickness burns,start feeding
within 6-18 hrs.
• Analgesia should be adequate.
• Closed dressing recommended for partial thickness burns.
17. CAUSES OF DEATH IN BURNS
• Primary shock or neurogenic shock
• Secondary shock due to fluid loss
• Smoke inhalation
• Toxaemia
• Septicaemia
• biochemical disturbances
• Acute renal failure
• oedema of glottis & pulmonary oedema
• Malignant transformation of burns scar {marjolin’s ulcer} after years
of recovery
18.
19. AUTOPSY FINDINGS:-
External :-
The body may demonstrate the
attitude.
Antemortem burns appear reddened &
blistered. Hair is signed or burnt.
Blisters may be seen , but they also in
postmortem burns, even in a
body.
20.
21. • Often there may be Signs of gross
infection of burns on a dead body with
discoloration & pus formation.
• Burning of clothes, singeing of hair,
charring of the body etc., are also seen ,
which are not seen in scalds.
• Heat ruptures may be evident , which
must not be confused with the
antemortem incised wounds.
22. Internal :-
• Blood may be cherry red in colour, due to the presence of
carboxyhaemoglobin.
• Extra dural heat haematoma may be seen
• Soot particles or carbonaceous material may be seen in the
respiratory passages due to smoke inhalation.
• Curling’s ulcers may be seen on stomach are duodenum.
• Serous pleural are common. Lungs are congested & appear
“cooked”
• Spleen & adrenal gland may be enlarged, congested & softened.
23. REFERENCES:-
• V.v.pillay
Text book of Forensic science & Toxicology.
• Dr. Ks. Narayan Reddy
The synopsis of Forensic Science & Toxicology.