The document discusses the process and objectives of a medico-legal autopsy. A medico-legal autopsy, also known as a post-mortem examination, is a scientific examination of a dead body that is carried out under state laws to determine the cause and manner of death and assist in legal investigations. It aims to establish the cause, manner, and estimated time of death, as well as identify the deceased individual and collect relevant tissues as evidence. The document outlines the typical process, examinations, and reporting of findings for a medico-legal autopsy.
An autopsy (post-mortem examination, obduction, necropsy, or autopsia cadaverum) is a surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause, mode and manner of death or to evaluate any disease or injury that may be present for research or educational purposes.
An autopsy (post-mortem examination, obduction, necropsy, or autopsia cadaverum) is a surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause, mode and manner of death or to evaluate any disease or injury that may be present for research or educational purposes.
Forensic science PowerPoint presentation on Injury and it's medico-legal importance.
The slide is made for medical students. Mainly for BAMS students. It covers maximum points.
The slide is full of example with pictures which make it easy to understand the concept. It contains post-mortem findings as well as medico-legal importance of the each type of injury.
Deals with the post-mortem examination (autopsy) particularly the internal examinations of the various organs based on Virchow's technique of organ removal.
Forensic science PowerPoint presentation on Injury and it's medico-legal importance.
The slide is made for medical students. Mainly for BAMS students. It covers maximum points.
The slide is full of example with pictures which make it easy to understand the concept. It contains post-mortem findings as well as medico-legal importance of the each type of injury.
Deals with the post-mortem examination (autopsy) particularly the internal examinations of the various organs based on Virchow's technique of organ removal.
in this topic of autopsy and embalming, various topics like definition of autopsy and embalming, purposes, steps, procedure, role of nurse is discussed.
this is a powerpoint presentation on external examination at autopsy, presented during pg program.. useful for both undergraduate and postgraduate students
In the presentation efforts have been made to guide the medical professionals how to deal with a MLC case in a step by step manner and certain issues relating to medical case records.
ANATOMY LAB DISSECTION, LUNGS AND HEART OF HUMAN CADAVER WITH DIFFERENT VIEWS AND LABELING OF EACH STRUCTURE IN EACH SLIDES
FOR MBBS 1ST YEAR, BDS, AND OTHER MEDICAL SCIENCES
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
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Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
1. AUTOPSYAUTOPSY
By Dr. Armaan SinghBy Dr. Armaan Singh
It means to see for oneself.It means to see for oneself.
(Auto(Auto== Self OpisSelf Opis==View)View)
-Clinical autopsy.-Clinical autopsy.
-Medico-legal autopsy.-Medico-legal autopsy.
2. Medico-legal autopsy or postMedico-legal autopsy or post
mortem examination is a specialmortem examination is a special
type of scientific examination oftype of scientific examination of
dead body carried out under thedead body carried out under the
laws of the state for thelaws of the state for the
protection of its citizens and toprotection of its citizens and to
assist the identification andassist the identification and
prosecution of the guilty.prosecution of the guilty.
3. OBJECTS AIMSOBJECTS AIMS
Cause of death.Cause of death.
Manner of death.Manner of death.
Time since death.Time since death.
To establish identity,To establish identity,
To retain relevant organs andTo retain relevant organs and
tissue as evidence.tissue as evidence.
Infants-Live birth and viability.Infants-Live birth and viability.
4. Rules for Medico-LegalRules for Medico-Legal
AutopsyAutopsy
Authorization.Authorization.
Identification.Identification.
Visit of scene of crime.Visit of scene of crime.
History of the case.History of the case.
Verification of the injuries noted byVerification of the injuries noted by
the police.the police.
Examination.Examination.
Notes.Notes.
Preservation of viscera and otherPreservation of viscera and other
tissue.tissue.
List of artifacts.List of artifacts.
5. Contents of the AutopsyContents of the Autopsy
reportreport
The preambleThe preamble
-Authority.-Authority.
-Time of arrival of body.-Time of arrival of body.
-Date and place of examination.-Date and place of examination.
-Name,Age and Sex.-Name,Age and Sex.
- Body identified by- Body identified by..
6. The body of the reportThe body of the report
-- External and internalExternal and internal
examination.examination.
- WoundsInjuries-- WoundsInjuries-
nature,direction,situationnature,direction,situation
and sizes.and sizes.
- Conclusions.- Conclusions.
7. ExternalExternal
examinationexamination
Condition of the bodyCondition of the body
Marks of identification.Marks of identification.
Eyes.Eyes.
State of naturalState of natural
orifices,ears,nostrils,mouth,anus,orifices,ears,nostrils,mouth,anus,
urethra and vagina.urethra and vagina.
Injuries-nature,position andInjuries-nature,position and
measurements.measurements.
State of limbs.State of limbs.
Genitals and breasts.Genitals and breasts.
8. ThoraxThorax
Walls, ribs and cartilages.Walls, ribs and cartilages.
Pleura and diaphragmPleura and diaphragm
Larynx,trachea and bronchi.Larynx,trachea and bronchi.
Lungs with weight.pericardium.Lungs with weight.pericardium.
Heart,cavities,valves andHeart,cavities,valves and
coronary vessels.coronary vessels.
Large vessels(Aorta)Large vessels(Aorta)
9. Poisoning casesPoisoning cases
Smell of the body and viscera.Smell of the body and viscera.
Postmortem staining and itsPostmortem staining and its
colour.colour.
If froth present,its nature.If froth present,its nature.
Colour of sclera, lips and nails.Colour of sclera, lips and nails.
Mouth and surroundings.Mouth and surroundings.
Injuries.Injuries.
Details of G.I tract examination.Details of G.I tract examination.
Description of stomach andDescription of stomach and
10. Viscera to be collected forViscera to be collected for
ChemicalChemical
ExaminationExamination
Stomach with contents.Stomach with contents.
Upper part of small intestine.Upper part of small intestine.
- 30cms with contents.- 30cms with contents.
500gms of liver and half of500gms of liver and half of
each kidney.each kidney.
5-10ml of blood.30ml of urine.5-10ml of blood.30ml of urine.
11. HangingLigatureHangingLigature
strangulation casesstrangulation cases
Description of ligature material.Description of ligature material.
Description of the ligatures mark.Description of the ligatures mark.
Marks of salivary dribble.Marks of salivary dribble.
Condition of eyes and pupils.Condition of eyes and pupils.
Colour of lips and nails.position ofColour of lips and nails.position of
tongue.tongue.
Distribution of postmortemDistribution of postmortem
staining.staining.
Presence of injuries on the body.Presence of injuries on the body.
12. Examination of neck sutures.Examination of neck sutures.
Injury to cervical spine and cord.Injury to cervical spine and cord.
Examination of internal organs.Examination of internal organs.
Preservation of viscera in cases ofPreservation of viscera in cases of
suspicion of poisoning.suspicion of poisoning.
13. Burns casesBurns cases
Smell from the body,keroseneSmell from the body,kerosene
other inflammable agents.other inflammable agents.
Nature of burns.Nature of burns.
- Antemortem- Antemortem
- Postmortem.- Postmortem.
Extent and degree of burns.Extent and degree of burns.
Age of burns.Age of burns.
Injuries other than burns.Injuries other than burns.
14. Colour of postmortem staining.Colour of postmortem staining.
Examination of air passages forExamination of air passages for
the presence of soot particles.the presence of soot particles.
Evidence ofEvidence of
-Poisoning.-Poisoning.
- Pregnancy,abortion,sexual- Pregnancy,abortion,sexual
assaults.assaults.
15. Negative AutopsyNegative Autopsy
When gross and microscopicWhen gross and microscopic
examination and otherexamination and other
investigations fail to reveal ainvestigations fail to reveal a
cause of death,the autopsy iscause of death,the autopsy is
considered to be negative.considered to be negative.
- Men.- Men.
- Material.- Material.
-Method.-Method.
16. MenMen
Lack of experience.Lack of experience.
Lack of training.Lack of training.
MaterialMaterial
Inadequate microscopicInadequate microscopic
examination.examination.
Insufficient laboratoryInsufficient laboratory
examination.examination.
Lack of toxicological analysis.Lack of toxicological analysis.
18. Obscure AutopsyObscure Autopsy
Which do not reveal the cause forWhich do not reveal the cause for
death in which there aredeath in which there are
trivial,equivocal or obscuretrivial,equivocal or obscure
findings or no positive findings.findings or no positive findings.
CausesCauses
Natural diseasesNatural diseases..
-Death by emotion or work stress.-Death by emotion or work stress.
-Death due to functional failure--Death due to functional failure-
20. PoisoningPoisoning
Narcotic poisoning.Narcotic poisoning.
Anesthetic over dosage.Anesthetic over dosage.
Neurotoxic or Cytotoxic poisons.Neurotoxic or Cytotoxic poisons.
Plant poisoning.Plant poisoning.
MiscellaneousMiscellaneous
Allergy.Allergy.
Drug idiosyncrasy.Drug idiosyncrasy.
21. ArtifactsArtifacts
May be defined as a change inMay be defined as a change in
the natural state of the body thatthe natural state of the body that
is likely to be misinterpreted atis likely to be misinterpreted at
autopsy.autopsy.
-Before death.-Before death.
-At the moment of death.-At the moment of death.
-After death.-After death.
-During autopsy.-During autopsy.
22. Before deathBefore death
Therapeutic artifacts.Therapeutic artifacts.
Surgical artifacts.Surgical artifacts.
At the moment ofAt the moment of
deathdeath
Agonal artifacts.Agonal artifacts.
Resuscitation artifactsResuscitation artifacts
23. After deathAfter death
Artifacts due to the handling ofArtifacts due to the handling of
the body.the body.
Artifacts related to rigor mortis.Artifacts related to rigor mortis.
Artifacts related to postmortemArtifacts related to postmortem
lividity.lividity.
Artifacts due to animal bite.Artifacts due to animal bite.
Artifacts due to chemicals.Artifacts due to chemicals.
Artifacts due to refrigeration.Artifacts due to refrigeration.
Embalming artifacts.Embalming artifacts.
24. Artifacts duringArtifacts during
autopsyautopsy
Air in blood vessels.Air in blood vessels.
Skull fractures.Skull fractures.
Visceral damage.Visceral damage.
Extravasation of blood.Extravasation of blood.
Fracture of hyoid bone.Fracture of hyoid bone.