Echocardiography is the main tool for evaluating prosthetic heart valves. Transthoracic echocardiography (TTE) is generally used to assess normal valve function and identify dysfunction like stenosis or regurgitation. Transesophageal echocardiography (TEE) provides better imaging of valve structure and is helpful for evaluating regurgitation and complications like endocarditis. Echocardiograms establish a baseline after valve implantation and monitor for issues like pannus, thrombus, infection or degeneration over time. TTE and TEE are complementary, with TEE used when TTE is inadequate or clinical suspicion remains after a TTE.
Atrial septal defect (ASD) closure can be performed surgically or percutaneously. Percutaneous closure is preferred for secundum ASDs that meet criteria such as defect size less than 38mm and adequate rim tissue. Echocardiography guides device placement and confirms closure. Complications include device embolization, arrhythmias, and erosion. Most studies report high success rates with percutaneous closure and shorter hospital stays than surgery. Surgical closure is preferred for sinus venosus, primum, or coronary sinus defects.
This document summarizes the evaluation of aortic valve stenosis using echocardiography. It describes the normal aortic valve anatomy and various types of aortic valve stenosis including calcific, bicuspid, rheumatic, and supravalvular or subvalvular stenosis. Doppler echocardiography is used to evaluate aortic valve stenosis severity based on valve area, mean gradient, and peak jet velocity. Stress echocardiography with dobutamine can help distinguish true severe from pseudo-severe low-flow, low-gradient aortic stenosis.
This document summarizes various devices used to close atrial septal defects (ASDs), including their designs, sizes, advantages, and disadvantages. The most commonly used device is the Amplatzer Septal Occluder, which has a double disc design and is self-expanding. Other devices discussed include the Gore HELEX, Lifetech/Cera, Figulla, Cardioseal/Starflex, and newer bioabsorbable options like the Biotrek. Complication rates of ASD device closure are generally low, below 10%, with embolization and arrhythmias being the most common issues. Larger trials have shown the Amplatzer to be very effective and easy
This document discusses Eisenmenger syndrome, a condition where pulmonary hypertension develops due to increased blood flow through defects between the systemic and pulmonary circulations. It provides details on causes, clinical features, pathology findings, and treatments. Key points include:
- Eisenmenger syndrome is caused by defects like VSDs, ASDs, and PDA that allow high blood flow to the lungs and cause pulmonary hypertension over time.
- Common causes of death include hemoptysis from pulmonary artery ruptures, heart failure, and complications from attempted defect repair surgery.
- Pathological findings show thickened pulmonary arteries that resemble the fetal pattern and contribute to high pulmonary vascular resistance.
- Medical treatments are generally ineffective once int
Ventricular septal defects (VSDs) are openings in the wall separating the ventricles of the heart. There are four main types classified by location: membranous, muscular, supracristal, and inlet VSDs. Echocardiography is useful for diagnosing VSDs and assessing their characteristics like location, size, and impact on cardiac function. VSDs range from small and asymptomatic to large defects causing heart failure or pulmonary hypertension. Surgical or catheter-based closure may be required for large VSDs.
Percutaneous Balloon Mitral Valvuloplasty (PBMV) is a procedure to dilated the mitral valve in the setting of rheumatic mitral valve stenosis. A catheter is inserted into the femoral vein, advanced to the right atrium and across the interatrial septum. Then the mitral valve is crossed with a balloon and it is inflated to relieve the fusion of the mitral valve commissures effectively acting to increase the mitral valve area and reduce the degree of mitral stenosis. Mitral regurgitation is a potential complication and thus PBMV is contraindicated if moderate or severe regurgitation is present. The Wilkins score examines mitral valve morphology and is determined via echocardiography to assess the likelihood of using PBMV based on certain echocardiographic criteria.
This document provides an overview of echocardiographic evaluation of restrictive cardiomyopathy. Key points include:
- Restrictive cardiomyopathy is characterized by a nondilated left ventricle with abnormal diastolic function and typically normal systolic function.
- Causes include infiltrative diseases like amyloidosis and storage diseases. Echocardiography can help diagnose but it is more difficult than other cardiomyopathies.
- Findings include low diastolic volume, normal ejection fraction, diastolic dysfunction with rapid early mitral inflow. Echocardiography helps differentiate restrictive cardiomyopathy from constrictive pericarditis.
This document discusses hemodynamic principles and various cardiac pressures measured in the circulatory system. It begins by explaining how electrical activity leads to mechanical functions that generate pressure waves. It then discusses how to measure and interpret pressures in different parts of the heart including the aorta, pulmonary artery, right and left ventricles, and right atrium. Factors that influence pressures and common abnormalities are provided. Diagrams of normal pressure waveforms are displayed. The document concludes by defining pulmonary and systemic vascular resistances.
Atrial septal defect (ASD) closure can be performed surgically or percutaneously. Percutaneous closure is preferred for secundum ASDs that meet criteria such as defect size less than 38mm and adequate rim tissue. Echocardiography guides device placement and confirms closure. Complications include device embolization, arrhythmias, and erosion. Most studies report high success rates with percutaneous closure and shorter hospital stays than surgery. Surgical closure is preferred for sinus venosus, primum, or coronary sinus defects.
This document summarizes the evaluation of aortic valve stenosis using echocardiography. It describes the normal aortic valve anatomy and various types of aortic valve stenosis including calcific, bicuspid, rheumatic, and supravalvular or subvalvular stenosis. Doppler echocardiography is used to evaluate aortic valve stenosis severity based on valve area, mean gradient, and peak jet velocity. Stress echocardiography with dobutamine can help distinguish true severe from pseudo-severe low-flow, low-gradient aortic stenosis.
This document summarizes various devices used to close atrial septal defects (ASDs), including their designs, sizes, advantages, and disadvantages. The most commonly used device is the Amplatzer Septal Occluder, which has a double disc design and is self-expanding. Other devices discussed include the Gore HELEX, Lifetech/Cera, Figulla, Cardioseal/Starflex, and newer bioabsorbable options like the Biotrek. Complication rates of ASD device closure are generally low, below 10%, with embolization and arrhythmias being the most common issues. Larger trials have shown the Amplatzer to be very effective and easy
This document discusses Eisenmenger syndrome, a condition where pulmonary hypertension develops due to increased blood flow through defects between the systemic and pulmonary circulations. It provides details on causes, clinical features, pathology findings, and treatments. Key points include:
- Eisenmenger syndrome is caused by defects like VSDs, ASDs, and PDA that allow high blood flow to the lungs and cause pulmonary hypertension over time.
- Common causes of death include hemoptysis from pulmonary artery ruptures, heart failure, and complications from attempted defect repair surgery.
- Pathological findings show thickened pulmonary arteries that resemble the fetal pattern and contribute to high pulmonary vascular resistance.
- Medical treatments are generally ineffective once int
Ventricular septal defects (VSDs) are openings in the wall separating the ventricles of the heart. There are four main types classified by location: membranous, muscular, supracristal, and inlet VSDs. Echocardiography is useful for diagnosing VSDs and assessing their characteristics like location, size, and impact on cardiac function. VSDs range from small and asymptomatic to large defects causing heart failure or pulmonary hypertension. Surgical or catheter-based closure may be required for large VSDs.
Percutaneous Balloon Mitral Valvuloplasty (PBMV) is a procedure to dilated the mitral valve in the setting of rheumatic mitral valve stenosis. A catheter is inserted into the femoral vein, advanced to the right atrium and across the interatrial septum. Then the mitral valve is crossed with a balloon and it is inflated to relieve the fusion of the mitral valve commissures effectively acting to increase the mitral valve area and reduce the degree of mitral stenosis. Mitral regurgitation is a potential complication and thus PBMV is contraindicated if moderate or severe regurgitation is present. The Wilkins score examines mitral valve morphology and is determined via echocardiography to assess the likelihood of using PBMV based on certain echocardiographic criteria.
This document provides an overview of echocardiographic evaluation of restrictive cardiomyopathy. Key points include:
- Restrictive cardiomyopathy is characterized by a nondilated left ventricle with abnormal diastolic function and typically normal systolic function.
- Causes include infiltrative diseases like amyloidosis and storage diseases. Echocardiography can help diagnose but it is more difficult than other cardiomyopathies.
- Findings include low diastolic volume, normal ejection fraction, diastolic dysfunction with rapid early mitral inflow. Echocardiography helps differentiate restrictive cardiomyopathy from constrictive pericarditis.
This document discusses hemodynamic principles and various cardiac pressures measured in the circulatory system. It begins by explaining how electrical activity leads to mechanical functions that generate pressure waves. It then discusses how to measure and interpret pressures in different parts of the heart including the aorta, pulmonary artery, right and left ventricles, and right atrium. Factors that influence pressures and common abnormalities are provided. Diagrams of normal pressure waveforms are displayed. The document concludes by defining pulmonary and systemic vascular resistances.
This document discusses various types and assessment of left ventricular dyssynchrony. It defines electrical and mechanical dyssynchrony. It describes different types of dyssynchrony including atrioventricular, interventricular, and intraventricular dyssynchrony. It discusses various echocardiography techniques to demonstrate and quantify each type of dyssynchrony, including M-mode, tissue Doppler, speckle tracking, and 3D echocardiography. It also mentions the use of MRI to assess dyssynchrony. The key application of assessing dyssynchrony is to predict response to cardiac resynchronization therapy in patients with heart failure.
This document discusses percutaneous pulmonary valve interventions. It begins by providing background on the history of pulmonary valve interventions, starting with open surgical techniques and moving to percutaneous approaches developed in the 1950s. It then discusses the first successful percutaneous pulmonary valve implantation in 2000. The document provides details on the anatomy of the pulmonary valve, causes of pulmonary valve disease, techniques for percutaneous balloon pulmonary valvuloplasty, indications and contraindications for percutaneous pulmonary valve interventions, and the evolution and indications for transcatheter pulmonary valve implantation.
This document discusses the history and technique of atrial septostomy. It describes how William Rashkind first developed the procedure in 1966 as a way to create an atrial septal defect without surgery. The document outlines the common indications for atrial septostomy in various congenital heart conditions. It provides details on the technical aspects of the procedure, including types of catheters, approaches, positioning, and success criteria. Complications are also mentioned, such as cardiac perforation which occurred in one case and was managed with surgery.
This document discusses strain and strain rate imaging techniques used to quantify regional myocardial function. It describes various methods to measure strain, including tissue Doppler, 2D speckle tracking, and cardiac MRI. It outlines normal values and patterns of strain in healthy individuals and how strain is altered in various cardiac diseases, such as coronary artery disease, heart failure, cardiomyopathies, and congenital heart disease. Strain imaging can identify myocardial scar, viability, dysfunction, and response to treatments.
The document provides an overview of right ventricular assessment using echocardiography. It discusses normal RV anatomy, segmental nomenclature, and coronary supply. Key metrics for evaluating RV size, wall thickness, function, and pressures are outlined. Normal values and technical aspects of measuring RV dimensions, area/fractional area change, tricuspid annular plane systolic excursion, myocardial velocity, and diastolic function are summarized. Hemodynamic assessment of pulmonary pressures is also reviewed.
Three sentences:
The document provides details on the anatomy and evaluation of aortic stenosis using echocardiography. It describes the normal aortic valve anatomy and how various types of aortic stenosis like calcific, rheumatic, bicuspid and subvalvular present on echo. Quantitative assessment of aortic stenosis severity is done using Doppler ultrasound to measure the maximum jet velocity and calculate the pressure gradient across the stenotic valve.
The document summarizes key aspects of cardiac catheterization and hemodynamic data collection. It describes the normal cardiac cycle, pressure measurement systems, normal pressure waveforms, methods to measure cardiac output like thermodilution and Fick, how to evaluate valvular stenosis and regurgitation, determine vascular resistance and shunts. Specific details are provided on assessing aortic stenosis, mitral stenosis, right-sided valves and quantifying regurgitant fractions. Oxygen saturation analysis and Fick principles are outlined for shunt determinations.
This document discusses the echocardiographic assessment of atrial septal defects (ASDs). It describes the main types of ASDs and notes that 80% are secundum defects. Echocardiography is used to identify and characterize ASDs, detect associated anomalies, diagnose complications, and guide treatment. Transthoracic echocardiography is the initial study, while transesophageal echocardiography provides better views of the atrial septum. Key measurements include ASD size, location, rim dimensions, and quantifying shunt severity with Qp/Qs. Echocardiography guides decisions about ASD device closure or surgery.
The document discusses various coronary artery anomalies including anomalies of origination, course, and intrinsic anatomy. Some key points include:
- Coronary artery anomalies have a global incidence of 5.64% and incidence of sudden death is 0.6%
- Anomalous origination of the left main coronary artery from the pulmonary artery (ALCAPA) is a rare but serious anomaly if left untreated
- Certain anomalous coronary artery courses, such as between the aorta and pulmonary artery, are associated with higher risks of sudden cardiac death
- Other anomalies discussed include single coronary arteries, coronary hypoplasia, ectasia/aneurysms, and intramural coronary arteries
This document provides information on Ebstein's anomaly, including its anatomy, embryology, clinical presentation, diagnosis, and natural history. Some key points:
- Ebstein's anomaly is a congenital defect involving downward displacement of the tricuspid valve into the right ventricle. This can cause dilation of the right atrium and dysfunction of the right ventricle.
- Clinical presentation varies from neonatal congestive heart failure to later cyanosis, arrhythmias, and right heart failure in adults. Associated defects are common.
- Diagnosis is made through echocardiogram demonstrating displacement of the tricuspid valve leaflets. Other tests like ECG, chest x-ray, and
preop TEE assessment of atrial septal defect is very important for making decision for device closure, properly assessed adequate rims of ASD will reduce risk of device embolization to almost nil.
1) Transthoracic and transesophageal echocardiography are important modalities for assessing atrial septal defects (ASDs). TTE can identify RV volume overload and septal flattening, while TEE precisely measures defect size and evaluates rim morphology.
2) The four main types of ASDs - ostium secundum, ostium primum, sinus venosus, and coronary sinus defects - have distinguishing echo features. Doppler can demonstrate shunt direction and magnitude.
3) Echocardiography guides percutaneous ASD closure by assessing defect and rim anatomy, device sizing, and post-procedure result. Understanding echo features is key to ensuring procedure success.
This document summarizes different devices used for closing ventricular septal defects (VSDs). It describes the common complications of VSD devices which are mostly minor, including embolization, arrhythmias, and conduction defects. Three types of Amplatzer devices are outlined - the muscular VSD device, asymmetric VSD occluder, and perimembranous VSD devices. Sizes and designs of each are provided. Results of post-myocardial infarction VSD closure show high residual leak rates. Finally, it briefly mentions some VSD devices manufactured in China including by Yatai and Lifetech, and introduces the novel NitOcclud VSD coil.
This document discusses pulmonary valve stenosis and balloon dilatation techniques. It provides background on the history and development of percutaneous pulmonary valvuloplasty. Key details include indications for the procedure, preprocedural evaluation and imaging, sedation and vascular access considerations, hemodynamic assessment, angiography, balloon catheter selection and use, and post-procedure protocol. The document serves as a reference for performing safe and effective balloon dilatation to treat pulmonary valve stenosis.
Evaluation of prosthetic valve function and clinical utility.Ramachandra Barik
Many of the prosthesis-related complications can be prevented or their impact minimized through optimal prosthesis selection in the individual patient and careful medical management and follow-up after implantation.
M-mode echocardiography uses rapid sampling of a region to create sequential parallel data lines, producing continuous horizontal lines representing points of brightness. This allows visualization of motion patterns over distance and time. Measurements of structures like the mitral valve can assess morphology, movement, velocity, and timing of cardiac events. Findings include increased wall thickness, reduced valve excursion, and fluttering indicating conditions like hypertrophy, stenosis, and regurgitation.
Stent thrombosis is a rare but devastating complication occurring in less than 1% of patients within 30 days of stenting and 0.2-6% annually afterwards. It is associated with higher thrombus burden and less procedural success, resulting in higher rates of death, recurrent heart attack, and recurrent stent thrombosis. Risk factors include stent-related issues like early versus late thrombosis, procedure-related issues like incomplete apposition or expansion, vessel-related issues like long lesions or small vessel size, and patient-related issues like diabetes, impaired heart function, renal disease, or non-compliance with dual anti-platelet therapy. Management depends on thrombus burden grade, with direct angioplasty and stenting for small burdens and
The document discusses atrial septal defects (ASDs), including indications for closure, procedural details, and echocardiographic assessment. Key points include:
- ASD closure is recommended in the presence of right-sided heart volume overload or symptoms. It prevents further deterioration and helps normalize heart size.
- Indications for closure include hemodynamically significant ASD, paradoxical embolism risk, and transient cyanosis. Contraindications include irreversible pulmonary hypertension.
- Echocardiography is used to assess defect size, rims, and shunt severity. Deficient rims, especially aortic and superior vena cava, increase erosion risk post-closure.
This document discusses prosthetic valve thrombosis (PVT), including its definition, pathogenesis, incidence, diagnosis, and treatment. PVT occurs when a blood clot forms on an artificial heart valve, interfering with its function. It is more common with mechanical valves and in the mitral position. Diagnosis involves blood tests, imaging like echocardiography and fluoroscopy. For non-obstructive small clots on the left side, initial treatment is usually heparin. Larger or obstructive clots may require surgery or fibrinolysis.
Prosthetic heart valve thrombosis can be treated with thrombolytic therapy or surgery. Thrombolytic therapy involves infusing a drug like streptokinase to dissolve the thrombus. The success rate of thrombolytic therapy is around 80% based on studies, with complete hemodynamic improvement observed in most cases. However, embolic events can still occur in around 20% of patients. Current guidelines recommend considering thrombolytic therapy for all NYHA classes of heart failure if individual patient factors support it over surgery. The optimal approach is to individualize treatment based on symptoms, thrombus burden, and surgical risk.
This document discusses various types and assessment of left ventricular dyssynchrony. It defines electrical and mechanical dyssynchrony. It describes different types of dyssynchrony including atrioventricular, interventricular, and intraventricular dyssynchrony. It discusses various echocardiography techniques to demonstrate and quantify each type of dyssynchrony, including M-mode, tissue Doppler, speckle tracking, and 3D echocardiography. It also mentions the use of MRI to assess dyssynchrony. The key application of assessing dyssynchrony is to predict response to cardiac resynchronization therapy in patients with heart failure.
This document discusses percutaneous pulmonary valve interventions. It begins by providing background on the history of pulmonary valve interventions, starting with open surgical techniques and moving to percutaneous approaches developed in the 1950s. It then discusses the first successful percutaneous pulmonary valve implantation in 2000. The document provides details on the anatomy of the pulmonary valve, causes of pulmonary valve disease, techniques for percutaneous balloon pulmonary valvuloplasty, indications and contraindications for percutaneous pulmonary valve interventions, and the evolution and indications for transcatheter pulmonary valve implantation.
This document discusses the history and technique of atrial septostomy. It describes how William Rashkind first developed the procedure in 1966 as a way to create an atrial septal defect without surgery. The document outlines the common indications for atrial septostomy in various congenital heart conditions. It provides details on the technical aspects of the procedure, including types of catheters, approaches, positioning, and success criteria. Complications are also mentioned, such as cardiac perforation which occurred in one case and was managed with surgery.
This document discusses strain and strain rate imaging techniques used to quantify regional myocardial function. It describes various methods to measure strain, including tissue Doppler, 2D speckle tracking, and cardiac MRI. It outlines normal values and patterns of strain in healthy individuals and how strain is altered in various cardiac diseases, such as coronary artery disease, heart failure, cardiomyopathies, and congenital heart disease. Strain imaging can identify myocardial scar, viability, dysfunction, and response to treatments.
The document provides an overview of right ventricular assessment using echocardiography. It discusses normal RV anatomy, segmental nomenclature, and coronary supply. Key metrics for evaluating RV size, wall thickness, function, and pressures are outlined. Normal values and technical aspects of measuring RV dimensions, area/fractional area change, tricuspid annular plane systolic excursion, myocardial velocity, and diastolic function are summarized. Hemodynamic assessment of pulmonary pressures is also reviewed.
Three sentences:
The document provides details on the anatomy and evaluation of aortic stenosis using echocardiography. It describes the normal aortic valve anatomy and how various types of aortic stenosis like calcific, rheumatic, bicuspid and subvalvular present on echo. Quantitative assessment of aortic stenosis severity is done using Doppler ultrasound to measure the maximum jet velocity and calculate the pressure gradient across the stenotic valve.
The document summarizes key aspects of cardiac catheterization and hemodynamic data collection. It describes the normal cardiac cycle, pressure measurement systems, normal pressure waveforms, methods to measure cardiac output like thermodilution and Fick, how to evaluate valvular stenosis and regurgitation, determine vascular resistance and shunts. Specific details are provided on assessing aortic stenosis, mitral stenosis, right-sided valves and quantifying regurgitant fractions. Oxygen saturation analysis and Fick principles are outlined for shunt determinations.
This document discusses the echocardiographic assessment of atrial septal defects (ASDs). It describes the main types of ASDs and notes that 80% are secundum defects. Echocardiography is used to identify and characterize ASDs, detect associated anomalies, diagnose complications, and guide treatment. Transthoracic echocardiography is the initial study, while transesophageal echocardiography provides better views of the atrial septum. Key measurements include ASD size, location, rim dimensions, and quantifying shunt severity with Qp/Qs. Echocardiography guides decisions about ASD device closure or surgery.
The document discusses various coronary artery anomalies including anomalies of origination, course, and intrinsic anatomy. Some key points include:
- Coronary artery anomalies have a global incidence of 5.64% and incidence of sudden death is 0.6%
- Anomalous origination of the left main coronary artery from the pulmonary artery (ALCAPA) is a rare but serious anomaly if left untreated
- Certain anomalous coronary artery courses, such as between the aorta and pulmonary artery, are associated with higher risks of sudden cardiac death
- Other anomalies discussed include single coronary arteries, coronary hypoplasia, ectasia/aneurysms, and intramural coronary arteries
This document provides information on Ebstein's anomaly, including its anatomy, embryology, clinical presentation, diagnosis, and natural history. Some key points:
- Ebstein's anomaly is a congenital defect involving downward displacement of the tricuspid valve into the right ventricle. This can cause dilation of the right atrium and dysfunction of the right ventricle.
- Clinical presentation varies from neonatal congestive heart failure to later cyanosis, arrhythmias, and right heart failure in adults. Associated defects are common.
- Diagnosis is made through echocardiogram demonstrating displacement of the tricuspid valve leaflets. Other tests like ECG, chest x-ray, and
preop TEE assessment of atrial septal defect is very important for making decision for device closure, properly assessed adequate rims of ASD will reduce risk of device embolization to almost nil.
1) Transthoracic and transesophageal echocardiography are important modalities for assessing atrial septal defects (ASDs). TTE can identify RV volume overload and septal flattening, while TEE precisely measures defect size and evaluates rim morphology.
2) The four main types of ASDs - ostium secundum, ostium primum, sinus venosus, and coronary sinus defects - have distinguishing echo features. Doppler can demonstrate shunt direction and magnitude.
3) Echocardiography guides percutaneous ASD closure by assessing defect and rim anatomy, device sizing, and post-procedure result. Understanding echo features is key to ensuring procedure success.
This document summarizes different devices used for closing ventricular septal defects (VSDs). It describes the common complications of VSD devices which are mostly minor, including embolization, arrhythmias, and conduction defects. Three types of Amplatzer devices are outlined - the muscular VSD device, asymmetric VSD occluder, and perimembranous VSD devices. Sizes and designs of each are provided. Results of post-myocardial infarction VSD closure show high residual leak rates. Finally, it briefly mentions some VSD devices manufactured in China including by Yatai and Lifetech, and introduces the novel NitOcclud VSD coil.
This document discusses pulmonary valve stenosis and balloon dilatation techniques. It provides background on the history and development of percutaneous pulmonary valvuloplasty. Key details include indications for the procedure, preprocedural evaluation and imaging, sedation and vascular access considerations, hemodynamic assessment, angiography, balloon catheter selection and use, and post-procedure protocol. The document serves as a reference for performing safe and effective balloon dilatation to treat pulmonary valve stenosis.
Evaluation of prosthetic valve function and clinical utility.Ramachandra Barik
Many of the prosthesis-related complications can be prevented or their impact minimized through optimal prosthesis selection in the individual patient and careful medical management and follow-up after implantation.
M-mode echocardiography uses rapid sampling of a region to create sequential parallel data lines, producing continuous horizontal lines representing points of brightness. This allows visualization of motion patterns over distance and time. Measurements of structures like the mitral valve can assess morphology, movement, velocity, and timing of cardiac events. Findings include increased wall thickness, reduced valve excursion, and fluttering indicating conditions like hypertrophy, stenosis, and regurgitation.
Stent thrombosis is a rare but devastating complication occurring in less than 1% of patients within 30 days of stenting and 0.2-6% annually afterwards. It is associated with higher thrombus burden and less procedural success, resulting in higher rates of death, recurrent heart attack, and recurrent stent thrombosis. Risk factors include stent-related issues like early versus late thrombosis, procedure-related issues like incomplete apposition or expansion, vessel-related issues like long lesions or small vessel size, and patient-related issues like diabetes, impaired heart function, renal disease, or non-compliance with dual anti-platelet therapy. Management depends on thrombus burden grade, with direct angioplasty and stenting for small burdens and
The document discusses atrial septal defects (ASDs), including indications for closure, procedural details, and echocardiographic assessment. Key points include:
- ASD closure is recommended in the presence of right-sided heart volume overload or symptoms. It prevents further deterioration and helps normalize heart size.
- Indications for closure include hemodynamically significant ASD, paradoxical embolism risk, and transient cyanosis. Contraindications include irreversible pulmonary hypertension.
- Echocardiography is used to assess defect size, rims, and shunt severity. Deficient rims, especially aortic and superior vena cava, increase erosion risk post-closure.
This document discusses prosthetic valve thrombosis (PVT), including its definition, pathogenesis, incidence, diagnosis, and treatment. PVT occurs when a blood clot forms on an artificial heart valve, interfering with its function. It is more common with mechanical valves and in the mitral position. Diagnosis involves blood tests, imaging like echocardiography and fluoroscopy. For non-obstructive small clots on the left side, initial treatment is usually heparin. Larger or obstructive clots may require surgery or fibrinolysis.
Prosthetic heart valve thrombosis can be treated with thrombolytic therapy or surgery. Thrombolytic therapy involves infusing a drug like streptokinase to dissolve the thrombus. The success rate of thrombolytic therapy is around 80% based on studies, with complete hemodynamic improvement observed in most cases. However, embolic events can still occur in around 20% of patients. Current guidelines recommend considering thrombolytic therapy for all NYHA classes of heart failure if individual patient factors support it over surgery. The optimal approach is to individualize treatment based on symptoms, thrombus burden, and surgical risk.
10.8.21 ECHO Normal prosthetic valve - FLOREN.pptxSittie Ali
The document discusses the echocardiographic assessment of normal prosthetic heart valves. It describes the different types of prosthetic valves, including mechanical and bioprosthetic valves. It outlines the echocardiographic evaluation of normal prosthetic valve function, including determining hemodynamic parameters like effective orifice area. It also provides guidance on assessing specific prosthetic valves located in the aortic and mitral positions. The echocardiographer must understand the normal function and imaging appearance of different prosthetic valves in order to identify any abnormalities.
Assessment of prosthetic valve functionSwapnil Garde
This document discusses the assessment of prosthetic valve function through various imaging modalities. It begins with an introduction to prosthetic valves and outlines topics to be covered, including classification of valve types. Evaluation methods like chest x-ray, fluoroscopy, echocardiography, and CT are described. Parameters assessed on each modality and guidelines for evaluation are provided. Complications of prosthetic valves and 3D imaging advances are also mentioned.
The document discusses the evaluation of prosthetic heart valves. It outlines various techniques used to evaluate prosthetic valves including history and physical exam, imaging modalities like chest x-ray, echocardiogram, CT and MRI. Echocardiography plays a key role in assessing prosthetic valve function by examining valve structure and mobility, quantifying stenosis or regurgitation, and identifying complications like thrombosis. Diagnosis of prosthetic valve dysfunction is based on changes in Doppler measurements of velocities, gradients and effective orifice areas compared to baseline. Prosthetic valve-patient mismatch can also occur and is assessed using echocardiography.
Long-term durability of conduits and valves used in correcting cardiac defects depends on factors like patient age and type of tissue. Significant pulmonary regurgitation and dysfunction requiring reoperation is common within 10 years of using a valved homograft. Transcatheter pulmonary valve replacement (tPVR) offers an alternative to repeat open-heart surgery. While tPVR has a high success rate and improves symptoms, complications like stent fracture and valve migration can occur. Patient selection and technique, such as pre-stenting, aim to minimize complications and extend time before future interventions.
Bioprosthetic valve thrombosis is more common than previously thought and can occur on both surgically and transcatheter implanted valves. While its true incidence is difficult to determine, risk factors include atrial fibrillation, subtherapeutic anticoagulation, obesity, and diabetes. Clinically, it most often presents as worsening dyspnea but can also cause thromboembolism or cardiogenic shock. Echocardiography is key to diagnosis but features like increased gradients, thickened leaflets, and reduced mobility must be considered in the context of the patient's history and risk factors. Treatment involves resumption of effective anticoagulation.
This document provides an overview of echocardiography for evaluating prosthetic heart valves after mitral or aortic valve replacement. It discusses the different types of replacement valves and the principles of echocardiographic assessment. For post-mitral valve replacement, the document describes the echo views and Doppler findings that should be assessed to evaluate valve function and identify any obstruction. It similarly outlines the echo views and parameters to examine for prosthetic aortic valves. Finally, it reviews potential complications of prosthetic valves including dysfunction, dehiscence, thromboemboli, and endocarditis.
1) Prosthetic heart valve thrombosis can occur with both mechanical and biological valves and is influenced by surface factors, hemodynamic factors, and hypercoagulability.
2) Clinical presentation may include heart failure symptoms or embolic events, and imaging with TEE is the standard for evaluation.
3) Treatment depends on severity of symptoms and includes anticoagulation, fibrinolytic therapy, or emergency surgery for severe cases.
Late complications in tof and redo surgeriesbackstabber089
Risk factors for death after tetralogy of Fallot (TOF) repair include age at repair, severity of right ventricle hypoplasia, and transannular patches. Without repair, 95% of patients die by age 40 from heart failure or hypoxia. Palliative shunt procedures augment pulmonary blood flow but risk shunt closure, infection, and pulmonary issues. Late complications include pulmonary regurgitation, right heart failure, and arrhythmias. Reoperations are often needed for residual lesions or valve replacement to preserve right ventricle function. Catheter interventions can treat residual stenosis but pulmonary valve replacement may be needed for severe, symptomatic pulmonary regurgitation.
Prosthetic valve thrombosis (PVT) occurs when a blood clot forms on an artificial heart valve. It is more common with mechanical valves compared to bioprosthetic valves. Risk factors include being under-anticoagulated, poor cardiac output, pregnancy, and hypercoagulable states. Echocardiography can diagnose PVT by detecting increased transvalvular gradients, thickened valve cusps, limited cusp motion, or visible thrombus. For severe PVT with heart failure symptoms, emergency surgery is recommended. For less severe cases, fibrinolytic therapy can restore normal valve function in 64% of patients and is a reasonable first-line treatment alternative to surgery.
Valular heart disease is very common in most of Afro Asian counteries mainly due to Rheumatic heart disease..Definitive treatment is surgery.which may be valve replacement or reapir. In this ppp I have discussed this subject in a simple way
Echo for transcatheter valve therapies - Copy.pptxAbhinay Reddy
This document discusses the role of echocardiography in assessing patients for and guiding transcatheter aortic valve implantation (TAVI). Echocardiography is used to evaluate aortic valve anatomy and geometry, assess suitability for different valve sizes, guide device positioning during the procedure, and evaluate complications. Key measurements include aortic annulus diameter, distance from the coronary ostia, and relationships to mitral valve and left ventricular outflow tract. Echocardiography provides real-time imaging during critical steps like valve deployment and balloon dilation to optimize positioning and identify paravalvular regurgitation. Follow up echos are important to evaluate prosthetic function and complications.
This document provides guidelines for the treatment of tetralogy of Fallot, which is the most common cyanotic congenital heart disease. Key points include:
- Surgical correction involves enlarging the right ventricular outflow tract and closing the ventricular septal defect. Palliative procedures like shunts or stents may be used for severe cases.
- Long term follow up is important to monitor for complications like arrhythmias and pulmonary valve insufficiency.
- Untreated tetralogy of Fallot has high mortality. Prenatal diagnosis allows delivery at a center equipped for pediatric cardiology/surgery.
This document discusses methods for evaluating the function of prosthetic heart valves. It begins by introducing different types of prosthetic valves and the importance of assessing valve function. The key methods discussed include clinical examination, chest x-ray, 2D echocardiography, Doppler echocardiography, TEE, 3D echo, cinefluoroscopy, CT scanning, and cardiac catheterization. Echocardiography poses technical challenges due to shadowing from prosthetic valves but allows assessment of hemodynamics and detection of dysfunction.
Transposition of great arteries with lvoto managementIndia CTVS
Transposition of the great arteries (TGA) with left ventricular outflow tract obstruction (LVOTO) can be managed through various surgical options depending on the severity and type of LVOTO. The Rastelli procedure and Lecompte procedure are two common definitive corrective surgeries that involve tunneling the left ventricle to the aorta while connecting the right ventricle to the pulmonary artery with or without a conduit. The Nikaidoh procedure, or aortic translocation, is an alternative used when anatomy is unsuitable for Rastelli or Lecompte, involving translocating the aortic root posteriorly to relieve LVOTO. Long-term outcomes of these procedures can include reintervention needs but provide
The document discusses strategies for salvaging failing vascular access in hemodialysis patients through techniques like balloon angioplasty and stent placement. It outlines the complications associated with vascular access and guidelines for monitoring access. Examples are provided of endovascular interventions performed to treat stenoses in arteriovenous fistulas and grafts.
This document summarizes coarctation of the aorta, including types, presentations, diagnostic evaluations, and interventions. Coarctation can be localized, involve tubular hypoplasia, or be an interruption. It often presents with hypertension and reduced pulses. Diagnosis involves evaluating gradients on angiography or echocardiogram. Treatment is usually catheter-based balloon angioplasty or stenting, though surgery was used historically. Complications include aneurysms, dissection, or recoarctation so follow-up is important.
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Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
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Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
7. • Echocardiography is the key noninvasive modality for
evaluation of prosthetic valve structure and function
• Transthoracic echocardiography (TTE) is the mainstay for
monitoring prosthetic valves and can generally identify
normal function as well as evidence of valve dysfunction
(stenosis).
• Transesophageal echocardiography (TEE) is helpful
particularly for assessment of valve structure and
prosthetic valve regurgitation especially involving
mechanical mitral and tricuspid prostheses as well as
assessment of endocarditis for all valves
• This topic will review echocardiography of prosthetic heart
valves
8.
9.
10. Baseline transthoracic
echocardiogram
American Heart Association/American College of Cardiology
(AHA/ACC) guideline recommendation to perform a transthoracic
echocardiogram (TTE) six weeks to three months after valve
implantation (when the hemoglobin has normalized) to evaluate
valve hemodynamics and to establish a baseline for future
comparison
The TTE should include Doppler measurements of transvalvular
velocities as well as assessment of valvular and paravalvular
regurgitation.
Adequate Doppler velocity recordings can generally be obtained
despite acoustic shadowing from valve prostheses.
11. • Transvalvular gradients for normally functioning prosthetic valves
are dependent upon
• valve type
• location
• size (as compiled in the 2009 American Society of
Echocardiography guidelines as well as patient-specific factors
• A higher than expected initial gradient is often due to a high
output state (eg, due to anemia) or patient-prosthetic mismatch
• It is only rarely due to early dysfunction of the prosthesis (eg,
thrombus formation or hemodynamically significant valvular
regurgitation)
• We suggest obtaining the postoperative baseline study after the
patient’s hemoglobin has returned to baseline to avoid recording a
gradient that is transiently higher than expected due to anemia.
12. Change in clinical status
The echocardiographer should be alert to the
range of complications that can occur with
prosthetic devices, including the following
Prosthetic obstruction due to
thrombus,
pannus ingrowth,
leaflet thickening, or
calcification of biologic prostheses.
14. • Prosthetic regurgitation due to
paravalvular leak,
prosthetic leaflet interference by thrombus,
or vegetation or leaflet tear of a
bioprosthesis.
15. Prosthetic valve endocarditis
• findings including vegetations and abscess
formation
• ●Prosthetic valve dehiscence with valve ring
instability/"rocking."
• ●Mechanical structural failure (eg, strut
fracture and component escape), which is
rare with current valve types.
16. • A TTE is recommended as the initial test in patients with
prosthetic valves with a change in clinical status suggestive
of valve dysfunction and/or endocarditis
• Symptoms and signs of bioprosthetic valve degeneration,
• pannus formation, or
• endocarditis include new exertional dyspnea,
• a louder murmur, or a new murmur.
• Symptoms and signs of mechanical valve dysfunction due
to thrombosis, pannus formation, or endocarditis include a
new or louder murmur, new onset of dyspnea, and signs of
heart failure, thromboembolism, and hemolysis.
17. • For patients with a prosthetic valve, a TTE may also be useful since
it provides proper alignment for Doppler assessment of
transvalvular velocities, gradient, and valve area.
• In patients with aortic prostheses, valvular regurgitation can be
reliably detected on TTE.
• For all patients with a prosthetic valve, TTE may be useful for
assessment of biventricular cavity size and systolic function as
well as an estimate of pulmonary artery systolic pressure.
18. • Transesophageal echocardiography has much
higher sensitivity for detection of
• prosthetic valve thrombi
• vegetations
• extravalvular extension of infection as well as
prosthetic mitral regurgitation.
19. Surveillance of old bioprosthetic
valves
Since the incidence of bioprosthetic valve dysfunction
markedly increases 10 years after implantation, we agree
with the 2014 AHA/ACC valve guidelines, which state
that a TTE is reasonable in patients with a bioprosthetic
valve after the first 10 years, even in the absence of
change in clinical status
The guideline suggested annual TTE thereafter, but every
two to three years may be reasonable if valve function is
normal with annual echocardiograms when valvular
dysfunction presents.
20. • However, in individuals at increased risk of early
valvular degeneration such as those with chronic
renal failure and young age at implantation, it is
reasonable to repeat echocardiography at five
years post-implantation and yearly thereafter
• Routine annual echocardiographic evaluation is
not indicated in patients with mechanical valve
prostheses with normal postoperative baseline
examination and no signs or symptoms of valve
dysfunction
21. KEY COMPONENTS OF THE
ECHOCARDIOGRAM
Echocardiographic evaluation of patients with prosthetic
valves includes
imaging of the valve and its seating;
assessment of valve hemodynamics
transvalvular velocities
identification and quantification of valve regurgitation
(intravalvular and paravalvular);
measurement of cardiac chamber sizes
left ventricular wall thicknesses
assessment of left ventricular systolic and diastolic
function
22. • Prosthetic valves are generally inherently
stenotic, so Doppler velocity recordings across
normally functioning valves are similar to those
of mild native valve stenosis
• Normal function of the valve is confirmed by
• evaluation of the contour of the jet velocity
• acceleration time (the time from onset of flow to
maximal velocity),
• the effective orifice area (EOA)
• Doppler velocity index (DVI).
23. • An increase in the transprosthetic velocity could be due to
• valvular obstruction,
• regurgitation, or an
• increase in cardiac output,
• Decrease in either the EOA or the DVI is more specific for
prosthetic obstruction.
A Doppler velocity pattern demonstrating normal transprosthetic flow
gradient and flow duration is usually sufficient to exclude a stenotic
valve
However, the gradient may not be elevated in the setting of
obstruction with low stroke volume.
• The EOA is calculated using the continuity equation:
• EOA = stroke volume/VTIPrV
24. • where VTIPrV is the velocity time integral through the prosthesis
determined by continuous wave Doppler.
• The stroke volume is generally derived from an adjacent site as
cross-sectional area (estimated from the associated diameter and
assuming a circular area) multiplied by the VTI of flow measured by
pulsed wave Doppler at that site.
• For prosthetic aortic and pulmonic valves, site for calculation of
stroke volume is at the site of flow just proximal to the valve.
• For prosthetic mitral valves, stroke volume may be calculated at
the aortic or pulmonary annulus if no significant regurgitation is
present.
25. Doppler velocity index or dimension
less index
• The DVI is a simplified method for evaluating
aortic valve obstruction.
• The DVI is the ratio of the velocity proximal to the
valve by pulsed wave Doppler to the velocity
through the valve by continuous wave Doppler.
• Use of this index avoids the need to measure
stroke volume
• A DVI <0.25 suggests significant valve
obstruction.
26. • Prosthetic aortic regurgitation (intravalvular or
paravalvular) can generally be identified by
transthoracic echocardiography (TTE).
• Prosthetic mitral regurgitation and tricuspid
regurgitation are usually difficult to assess on
TTE due to acoustic shadowing and thus
transesophageal echocardiography (TEE) is
preferred.
27. Role of TTE and TEE
TTE and TEE are complementary in the evaluation of prosthetic valves.
As mentioned, acoustic shadowing caused by prosthetic material may limit
TTE visualization of
prosthetic discs/leaflets,
vegetations, abscesses
and thrombi.
In addition, while prosthetic aortic valve regurgitation is usually well
visualized on TTE color Doppler imaging, prosthetic mitral regurgitation is
frequently undetectable
As a result, TEE is the imaging method of choice when the TTE is technically
inadequate or when there are borderline findings on the TTE in a patient in
whom there is a strong clinical suspicion of prosthetic malfunction
28. Complications of prosthetic valve
• Paravalvular leak
• Endocarditis
• Extrinsic interference of function (pannus, thrombus,
vegetation) resulting in obstruction and/or
regurgitation
• Leaflet tears of bioprosthesis
• Leaflet calcification/stenosis of bioprosthesis
• Ball variance, now rare as ball in cage valves are no
longer implanted
• Strut fracture and component escape, also now rare
with newer-generation valves
29. • It is worth mentioning the finding of
microbubbles, which can be seen in an
otherwise normally functioning mechanical
prosthesis and are not associated with valve
pathology.
• They are usually seen with mitral prostheses
within the left ventricular inflow and are likely
due to degassing of carbon dioxide
30. FEATURES OF VALVE DYSFUNCTION
• Prosthetic valve obstruction —
• Prosthetic valve obstruction should be
suspected in a newly symptomatic patient
with a rise in transprosthetic gradient from a
baseline determination or from established
normal values for valves of that type and size.
• The expected range of Doppler gradients and
effective orifice area encountered in properly
functioning valves.
32. Thrombus formation in St judes
mechanical Prosthetic valve . After
successful thrombolysis mean gradient
hasd significantly reduced
33.
34. • Causes of obstruction include pannus ingrowth,
thrombus, and vegetation
• Clinical clues to this possibility include the age of
the valve and the adequacy of anticoagulation. In
a bioprosthesis or heterograft, the leaflets
themselves may become calcified and immobile.
• There has been an increasing recognition of
subclinical thrombus formation on bioprosthetic
valves, which appears to be more common in
percutaneous valves than in surgically placed
valves as discussed separately
35. • Once there is a high suspicion of obstruction, transesophageal
echocardiography (TEE) should be performed for etiologic definition
with both mechanical and bioprosthetic valves, especially for mitral
prostheses.
• Doppler transthoracic echocardiography (TTE) is the primary
means to diagnose prosthetic valve obstruction; hemodynamic
cardiac catheterization is not routinely needed
• 3D-TEE may be helpful in identifying pannus, although its utility has
not been well defined
• Computed tomography (CT) scan is an important adjunctive imaging
modality.
36. • In the case of suspected aortic pannus, the
distal end of the left ventricular outflow tract
should be examined both with imaging and
with color flow Doppler.
• Pannus tends to lie close to the valve ring and
can be easily overlooked.
37. • In the mitral position, the same procedure should be followed.
• Finding a high grade of spontaneous contrast in the left atrium,
with or without thrombi, or finding thrombus around the sewing
ring in the setting of adequate anticoagulation should heighten
suspicion of pannus formation.
• Thin fibrillar strands may also be encountered adjacent to the
mitral annulus and on the sewing ring of the valve.
• These structures are brightly reflective and highly mobile and may
or may not be associated with a pathologic process.
38. Distinction between thrombus and
pannus
• The most common etiology for prosthetic
valve obstruction is thrombus formation;
pannus formation due to fibrous tissue
ingrowth is far less common.
• Since treatment options for thrombus and
pannus differ, it is important to distinguish
between these two causes.
39. • Echocardiographic differentiation of pannus and
thrombus may be difficult. In general:
• ●Thrombus tends to be larger, mobile, be
somewhat less echo-dense, and more commonly
associated with spontaneous echo contrast.
• ●Pannus is highly echogenic, consistent with its
fibrous composition; is usually firmly fixed
(minimal mobility) to the valve apparatus; and
mostly involves the sewing ring, which may
make it difficult to distinguish from the ring
40. • In order to establish factors associated with the
presence of thrombus, one study evaluated the
findings on a preoperative TEE in 53 patients with an
intraoperative diagnosis of pannus or thrombus
• Predictors of thrombus or a mixed presentation
(pannus and thrombus) included:
Mobile mass
Attachment of mass to valve occluder
Elevated gradients
An international normalized ratio ≤2.5
41. Prosthetic valve regurgitation
• Physiologic regurgitation, the so-called "seating
puff" of angiography, is universally encountered
with mechanical valves and dependent in degree
on the type of prosthesis used.
• However, severe regurgitation may result from
bioprosthetic valve leaflet degeneration or
destruction from endocarditis, mechanical valve
pannus, thrombus, or vegetation that interferes
with mechanical leaflet function.
42. Physiologic regurgitation
All mechanical valves exhibit some degree of obligatory
regurgitation of up to 15 mL of blood
The physiologic regurgitation associated with prosthetic
valves appears only briefly and is due to retrograde
volume displacement as the valve leaflets close
. This type of regurgitation is detected by highly sensitive
color flow Doppler imaging on TEE.
In addition, a certain amount of more prolonged
"leakage backflow" regurgitation occurs after the valve
closes .
These are often referred to as "washing jets," believed
to inhibit the formation of thrombi.
43. • Normally functioning mechanical valves, such as the
bileaflet St. Jude prosthesis, usually have two to four
centrally directed regurgitant jets.
• Features associated with these jets include a low
intensity and only minimal penetration into the
atrium, generally less than 3 cm
• The monodisc Medtronic-Hall valve has two jets, one
of which is prominent and longer
• Normally functioning bioprosthetic and heterografts
are less likely to have these small regurgitant signals;
when mild regurgitation is present, there is usually one
central jet
44. Pathologic regurgitation
• Most pathologic regurgitation associated with
mechanical valves is perivalvular.
• However, occasionally, disc closure may be
impeded by a vegetation or thrombus leading to
combined stenosis and regurgitation.
• If TTE does not reveal the offending mass or
tissue, TEE should be performed.
• Bioprostheses with leaflet degeneration may
exhibit central pathologic regurgitation that is
broad-based when severe.
45. Paravalvular regurgitation
• — Trace or mild paravalvular regurgitation immediately following
valve replacement is common with both mechanical and
bioprosthetic prostheses and generally not progressive.
• Paravalvular regurgitation can develop late after valve replacement
due to suture dehiscence, from a poorly seated ring, or from
endocarditis leading to valve dehiscence.
• Hemolysis is a common complication of these leaks, especially
when they occur with a mitral valve prosthesis
• Paravalvular regurgitation should be suspected when a patient
with a prosthetic valve presents with hemolytic anemia.
46. • To recognize a paravalvular leak, TEE must be performed with a high
color frame rate in several views from several angles outside the
sewing ring
• There should be a careful search for periprosthetic leaks around as
much of the valve circumference as possible and an attempt made
to define the extent of the regurgitation once it is identified.
• The origin of a periprosthetic leak may appear deceptively narrow
when caused by disruption of a limited number of sutures.
• Three-dimensional echocardiography is helpful in mapping the
extent of the paravalvular leak and has proven efficacious for
guiding percutaneous device closure of these leaks.
47. Prosthetic valve dehiscence
• Prosthetic valve dehiscence is identified on echocardiography as a
separation of the prosthetic ring from the native valvular annulus and is
usually accompanied by paravalvular regurgitation.
• Valve dehiscence is most frequently caused by endocarditis.
• Rocking of a prosthetic valve is a sign of dehiscence, particularly in the
aortic position.
• Rocking of a prosthetic mitral valve can be caused by dehiscence or by
retained native posterior leaflet or posterior and anterior leaflets, with the
latter generally not accompanied by paravalvular regurgitation
• Prosthetic valve dehiscence may be identified by TTE but is frequently
better visualized with TEE
48. Thromboembolism
• In patients with a suspected cardiac cause for
embolism, the source may be a thrombus
from a nonobstructed or obstructed
prosthetic heart valve.
49. SPECIFIC PROSTHETIC VALVE
DISORDERS
• Prosthetic aortic stenosis — Aortic prosthetic
obstruction may be due to thrombus or
vegetation, pannus ingrowth, or progressive
leaflet degeneration in the case of a
bioprosthetic valve.
50.
51. • we agree with the American Society of
Echocardiography algorithm for diagnosis of
prosthetic aortic stenosis
• ●If the peak velocity across the aortic
prosthesis is greater than 3 m/sec or if there is
a significant increase over baseline, the
Doppler velocity index (DVI) should be
calculated.
54. • Further analysis should include measurement of
the acceleration time (AT), which is the time from
transvalvular flow onset to maximal velocity
• An AT <100 msec is consistent with normal
function, whereas an AT >100 msec is concerning
for obstruction and further evaluation is
warranted.
• A DVI <0.25 suggests prosthetic aortic valve
stenosis if accompanied by an AT >100 msec.
55. • Finally, the effective orifice area (EOA) indexed by
body surface area can provide evidence of
patient-prosthetic mismatch when the
transprosthetic velocity is high but the DVI is
>0.25 and the AT is <100 msec.
• Patient-prosthetic mismatch is suggested by an
EOA index of <0.8 cm2/m2 and is considered
severe when the EOA index is <0.65 cm2/m2
56. • When prosthetic aortic valve stenosis is
suspected, the transthoracic
echocardiography (TTE) is usually not
adequate for visualization of the leaflet
motion or presence of thrombus and thus
warrants further investigation with
fluoroscopy of a mechanical valve and/or
transesophageal echocardiography (TEE)
57. Prosthetic aortic regurgitation
Mechanical prosthetic valves displace blood
when the occluder disc closes and may also have
small holes in the occluders and at hinge points;
the pattern is characteristic for the valve type
• Biologic valves may have minor degrees of
central regurgitation, which are detectable
due to the high sensitivity of color flow
Doppler.
58.
59. • Grading the severity of pathological prosthetic aortic
regurgitation can be challenging and an integrative
approach is recommended
• When there is significant dehiscence of the valve (more
than 40 percent), a rocking motion is detected, which is
usually associated with severe regurgitation.
• The following features suggest severe regurgitation: jet
width >65 percent, pressure half-time <200 msec,
holodiastolic flow reversal in the descending aorta,
regurgitant volume >60 mL, and a regurgitant fraction >50
percent
• In addition, chronic severe aortic regurgitation is a cause of
left ventricular dilation.
60. • While TTE can detect and often grade
prosthetic aortic regurgitation, the cause is
often not apparent.
• TEE should be performed in order to diagnose
endocarditis with or without abscess,
thrombus interfering with disc closure, and
bioprosthetic leaflet tears.
61. Prosthetic mitral stenosis
• Prosthetic mitral valve obstruction can also
occur because of thrombus, pannus,
vegetation, and bioprosthetic leaflet
thickening or calcification.
• The peak transmitral velocity, the mean
gradient, and pressure half-time should all be
considered in the context of the heart rate
and compared with previous
echocardiographic studies.
62. Prosthetic mitral regurgitation
• Since the color Doppler jet is usually obscured because of
acoustic shadowing caused by the prosthesis, other clues to
regurgitation must be heeded
• There may be increased rocking of the prosthesis
associated with dehiscence of the sewing ring.
• The peak transmitral E wave velocity is increased as is the
mean gradient, although the pressure half-time remains
within normal range.
• The left ventricular volume may be increased and the
ejection fraction is usually preserved.
• However, in the presence of significant mitral regurgitation,
the forward stroke volume falls, which can be inferred by a
decrease in the left ventricular outflow tract VTI.
63.
64. Prosthetic tricuspid valve dysfunction
• The principles for evaluating the prosthetic
tricuspid valve are similar to that of the mitral
valve.
• Bioprostheses are more commonly used than
mechanical prostheses in the tricuspid
position due to issues of valve thrombosis.
• Because of the respirophasic variation in
transtricuspid velocities, at least five beats
should be measured.
65. summary
• Transthoracic echocardiography (TTE) is helpful in
evaluating prosthetic valve function, particularly valve
gradients, but views are frequently limited for assessment
of vegetations, thrombus, and regurgitation, especially for
mitral and tricuspid prostheses.
• ●Transesophageal echocardiography (TEE) is particularly
helpful in detecting paravalvular leak, prosthetic mitral and
tricuspid regurgitation, vegetation, abscess, valve
obstruction, ball variance, strut fracture and component
escape, bioprosthetic leaflet tears, and bioprosthetic
calcification/stenosis.
• As a result, initial TEE is often preferred. A TTE may be
more useful to assess chamber sizes and ventricular
function.
66. • ●A TTE with Doppler measurements of transvalvular velocities
obtained six weeks to three months after prosthetic valve
implantation (when the hemoglobin has normalized) is helpful to
establish a baseline for future comparison.
• ●Complications of prosthetic valves include prosthetic valve
obstruction, regurgitation, endocarditis, dehiscence, and
mechanical structural failure (rare with current valve types).
• ●We suggest monitoring by TTE starting 10 years after implantation
of a bioprosthetic valve due to the risk of valve degeneration.
• However, in patients with risk factors for early deterioration such
as those with renal failure and implantation at younger ages, it is
reasonable to start monitoring at five years.
67. • Trace or mild paravalvular regurgitation immediately following valve
replacement is common and generally not progressive. Paravalvular
regurgitation can develop late after valve replacement due to broken or
dehisced sutures, from a poorly seated ring, or from endocarditis
(dehiscence
• ●Prosthetic valve obstruction should be suspected when a patient
develops symptoms of heart failure and increased transprosthetic
gradient. TEE is the primary means to confirm prosthetic valve obstruction
and investigate its causes (pannus, thrombus, or vegetation).
• ●Pathologic, intense prosthetic valve regurgitation can result from
bioprosthetic valve degeneration, mechanical valve pannus, thrombus, or
vegetation
• ●Systemic emboli can arise from nonobstructive or obstructive valve
thrombosis.