Thank you for the feedback. I will incorporate your suggestions in any future presentations. The goal is to communicate information clearly and concisely while also properly citing sources.
- What it is.
- How & Why people use it.
- Effects: (Physiological; Psychological; Behavioural).
- Short-term risks.
- Long-term consequences.
- Risk Reduction: (Strategies; Behaviours).
- Working with intoxication.
- Why now? Again!
- Community responses.
- Supports & Resources.
sedative and hypnotic over view in brief, sleep cycle, benzodiazipines,barbiturates,sedation,hypnosis, why barbiturates has less therapeutic index than benzodiazipines,
- What it is.
- How & Why people use it.
- Effects: (Physiological; Psychological; Behavioural).
- Short-term risks.
- Long-term consequences.
- Risk Reduction: (Strategies; Behaviours).
- Working with intoxication.
- Why now? Again!
- Community responses.
- Supports & Resources.
sedative and hypnotic over view in brief, sleep cycle, benzodiazipines,barbiturates,sedation,hypnosis, why barbiturates has less therapeutic index than benzodiazipines,
Performance enhancers bad effects of doping avik basuWbuhs
2nd and 3rd September 2011,a General Lecture Theatre, Dr Chirantan Mandal, Dr Avik Basu, Dr Dipayan Sen Dr Ushnish Adhikari,Dr Srimanti Bhattacharya, Dr Shubham Presided by Dr Arnab Sengupta (Physiology Dept Medical College Kolkata)
2nd and 3rd September 2011,a General Lecture Theatre, Dr Chirantan Mandal, Dr Avik Basu, Dr Dipayan Sen Dr Ushnish Adhikari,Dr Srimanti Bhattacharya, Dr Shubham Presided by Dr Arnab Sengupta (Physiology Dept Medical College Kolkata)
In competitive sports, doping is the use of banned athletic performance-enhancing drugs by athletic competitors. The term doping is widely used by organizations that regulate sporting competitions. The use of drugs to enhance performance is considered unethical, and therefore prohibited, by most international sports organizations, including the International Olympic Committee. Furthermore, athletes (or athletic programs) taking explicit measures to evade detection exacerbate the ethical violation with overt deception and cheating.
Continuing Education for mental health and substance abuse counselors and therapists. Reviews types of steroids, side effects and effects on sports performance.
Impact of anabolic steroids & other appearance & performance enhancing drugs ...MD Hammad Choudhary
Anabolic steroids are synthetic, or human-made variations of the male sex hormone testosterone. The proper term of these compounds is anabolic-androgenic steroids (AAS). These are the most popularly used class of Appearance & Performance enhancing drugs (APEDs) hence called steroidal APEDs.
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
Contact us if you are interested:
Email / Skype : kefaya1771@gmail.com
Threema: PXHY5PDH
New BATCH Ku !!! MUCH IN DEMAND FAST SALE EVERY BATCH HAPPY GOOD EFFECT BIG BATCH !
Contact me on Threema or skype to start big business!!
Hot-sale products:
NEW HOT EUTYLONE WHITE CRYSTAL!!
5cl-adba precursor (semi finished )
5cl-adba raw materials
ADBB precursor (semi finished )
ADBB raw materials
APVP powder
5fadb/4f-adb
Jwh018 / Jwh210
Eutylone crystal
Protonitazene (hydrochloride) CAS: 119276-01-6
Flubrotizolam CAS: 57801-95-3
Metonitazene CAS: 14680-51-4
Payment terms: Western Union,MoneyGram,Bitcoin or USDT.
Deliver Time: Usually 7-15days
Shipping method: FedEx, TNT, DHL,UPS etc.Our deliveries are 100% safe, fast, reliable and discreet.
Samples will be sent for your evaluation!If you are interested in, please contact me, let's talk details.
We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
Follow us on: Pinterest
Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
3. DRUGS IN SPORTS
are various substances providing
advantage in athletic performance
enlarging muscles
increasing the blood's oxygen-carrying
capacity.
the use of such drugs is competitively
unethical and medically dangerous.
outlawed by organizations that govern
major amateur and professional sports."
Oct. 20, 2008 - MSN Encarta Online Encyclopedia
4.
5. Why do athletes use drugs?
• enhances performance
• ease of availability
• physical and psychological dependence
• to cope and manage stress
• culture of the sport
• lack of confidence
• pressure to win
• prestige and fame
• national pride and unrealistic expectations
6.
7. Stimulants (amphetamines, caffeine, cocaine,
other sympathomimetic drugs).
Steroids (synthetic derivatives of the male sex
hormone testosterone).
Human growth hormone (HGH)
Blood Doping and Erythropoietin.
8. 1. Stimulants
act directly on the central nervous
system
speed up parts of the brain and body.
Adrenaline is an example of a naturally
occurring stimulant in the body.
increase alertness and fierceness
even decrease the exhaustion of athletes.
Stimulants historically were used
can suppress appetite
to treat asthma and other
reduce fatigue respiratory problems, obesity,
increasing your heart rate, blood neurological disorders, and a
pressure, body temperature and variety of other ailments
metabolism.
The most common stimulants include caffeine and amphetamines (Dexedrine,
The most common stimulants include caffeine and amphetamines (Dexedrine,
Benzedrine).
Benzedrine).
Cold remedies often contain the stimulants ephedrine, pseudoephedrine
Cold remedies often contain the stimulants ephedrine, pseudoephedrine
hydrochloride (Sudafed) and phenylpropanolamine (Acutrim).
hydrochloride (Sudafed) and phenylpropanolamine (Acutrim).
Street drugs such as cocaine and methamphetamine also belong to this group.
Street drugs such as cocaine and methamphetamine also belong to this group.
9. Potential short-term side effects Stimulants can be taken orally in pill form,
Stimulants can be taken orally in pill form,
• headaches inhaled nasally, smoked, or injected
inhaled nasally, smoked, or injected
• increased blood pressure
• increased heart rate
• insomnia
• weight loss
• hallucinations
• convulsions
• heart rhythm abnormalities
• heart attack
Long-term use
• uncontrollable movements of the face
• paranoid delusions
• nerve damage
• irritability
• insomnia
• confusion
• tremors
• anxiety
• irregular heartbeat
• dizziness
• hypertension
10. 1. Anabolic steroids or Lean
mass builders
• increase growth of muscles, bone
growth, speed and appetite.
• help reduce body fat.
• leads to severe health problems,
including “steroid rage” (the
development of male features in
female athletes, heart attacks, and
seriously reduced life expectancy.)
•synthetic derivatives of testosterone, a
natural male hormone.
•chemically manufactured.
•can be administered by injection, or can be
taken orally.
• Injectable steroids are longer lasting in the
body and can be detected in the body for a
longer period of time.
These are commonly used by cancer and AIDS patients and body
These are commonly used by cancer and AIDS patients and body
builders
builders
11. From the 1930's to the 1960's scientists modified the structure of the testosterone molecule to
From the 1930's to the 1960's scientists modified the structure of the testosterone molecule to
produce anabolic steroids to increase muscle and body protein metabolism at dose levels which
produce anabolic steroids to increase muscle and body protein metabolism at dose levels which
tend not to increase other secondary sexual characteristics
tend not to increase other secondary sexual characteristics
12.
13. 3. Blood Doping and Erythropoietin
'blood doping' -increasing the
'blood doping
number of red blood cells
(RBCs) in one's circulatory
system
enhance the delivery of
oxygen to one's muscles.
Improved oxygen delivery, in
turn, might help the muscles
perform better.
17. Erythropoietin
(EPO) a glycoprotein hormone
that controls erythropoiesis or
red blood cell production
stimulates bone marrow to
produce more red blood cells and
therefore hemoglobin
18. Is Erythropoietin (EPO) Dangerous?
•EPO injections thicken the blood, which
increases the strain on the heart. This is
particularly dangerous when the heart rate slows
down, such as during sleep.
•increased thickness, or viscosity, of the blood
increases the risk of blood clots, heart attacks,
and strokes.
•EPO is on the banned substances list in
professional cycling, and riders.
19. Side effects of Erythropoietin
•Increased viscosity of the blood
•Fever
•Seizures
•Nausea
•Headache
•Anxiety
20. Detection of Blood Doping And
Erythropoietin
•Random and often-repeated search
of athletes’ homes and tem
facilities
•Blood and urine testing
•Detection of unnatural number
population of RBC’s
•Comparisson of the numbers of
mature and immature RBC’s
21. 4.Human growth hormone (HGH)
• Human growth hormone (HGH), or
somatotropin- glycoprotein hormone
synthesised and secreted by cells in
anterior pituitary gland.
• cellular metabolism and is also necessary
for skeletal growth in humans.
• The major role in body growth is to
stimulate the liver and other tissues to
secrete insulin.
• Injection form only
• is a prohibited substance both in and
out of competition under the World
Anti-Doping Code 2008 Prohibited List."
22. The side effects of HGH are serious.
•Diabetes
• swelling
•high blood pressure
•even heart failure.
•Inflammation can also occur, causing joint pain and carpel
tunnel syndrome.
•increased risk of cancer in children using HGH
supplementation and a possible increase risk of cancer in
adults (though no long-term studies have been done to
prove or disprove the cancer risk of HGH).
23. Drug Tests Used in Sports
Drug Tests in Use (as of Dec. 22, 2008) Test Type Test For
Multiple illegal
1.Liquid Chromatography Hair
substances
Multiple illegal
2.Gas Chromatography/Mass Spectrometry Urine
substances
3.Testosterone/Epitestosterone Ratio Urine Testosterone
4.Carbon Isotope Ratio Urine Testosterone
5.Human Growth Hormone (HGH/rHGH) Blood HGH/rHgH
6.Isoelectric Erythropoietin (EPO) Focusing Urine Erythropoietin (EPO)
7.
Blood CERA EPO
Continuous Erythropoiesis Receptor Activator (CERA)
8. Hydropyrolysis Urine Steroids
9. Nanotrap Urine HGH/rHgH
10. Testosterone masking
Blood
Selective Androgen Receptor Modulators (SARMs) agent
11. Myostatin InhibitorAA Blood Gene manipulation
12. Gene Doping Blood/Tissue/Urine Gener manipulation
26. The PROS and CONS statements below give a five minute introduction
to the debate over performance enhancing drugs in sports.
1.Health Risk 6.Legalizing Performance
2.Seeking an "Unfair" Advantage Enhancing Drugs
3.Drugs vs. Technology 7.Sportsmanship
4.Coercion 8.Athletes as Role Models
5.Effectiveness of Drug 9.Sports Fans
Testing 10.Hall of Fame Induction
29. Injectables
• it may be impossible for
certain patients to take
tablets. These include
patients who are vomiting,
unconscious or for one
reason or another are not
able to take anything by
mouth.
30. Additional comments
1. Use bullets in your slides, limiting these to 3-5 words each
2. Provide pictures for each drug if there are any; explain how are these taken
(i.e., pill, IV, cream, etc.)
3. Include the word format of your document when you submit this to me (soft
copy)
4. Please indicate your references
Prof. J. Inovero
AP3
8/12/2010