2nd and 3rd September 2011,a General Lecture Theatre, Dr Chirantan Mandal, Dr Avik Basu, Dr Dipayan Sen Dr Ushnish Adhikari,Dr Srimanti Bhattacharya, Dr Shubham Presided by Dr Arnab Sengupta (Physiology Dept Medical College Kolkata)

1. EXERCISE AND SPORTS PHYSIOLOGY PERFORMANCE ENHANCERS IN SPORTS Presented by: AVIK BASU

2. WHAT IS ‘PERFORMANCE ENHANCEMENT’ IN SPORTS? 3… 2… 1…

3. Introduction In 1997, Sports Illustrated asked 198 aspiring US Olympians, “Would you take a banned performance enhancing substance if you were guaranteed to win and not get caught?” 98% said “YES”

4. Then, when asked, “Would you take the same undetectable substance if it would contribute to winning every competition for 5 years, then result in death?” Over 50% still said “YES!!!”

5. When your best just isn’t good enough…

6. DRUGS USED AS PERFORMANCE ENHANCERS Anabolic Agents Peptide Hormones and Analogues Creatine Stimulants Diuretics Cannabinoids

10. Adverse lipid profile

11. Premature epiphyseal closure

13. Insulin-like Growth factor

14. ErythropoietinProtein anabolic action Newly discovered Increases PCV

17. STIMULANTS Increased alertness Increased catecholamine Increased lipolysis CNS stimulation Improved respiratory function Allays fatigue

21. Adverse Effects:- (1) Lowered psychomotor performance (2) Altered perception

23. Gene Doping

25. THANK YOU!