Radiation dose modulation and dose
reduction techniques
Introduction to presentation
CT Dose Index
CTDI100
CTDIvol
DLP
Effective dose
CT dose reduction techniques
AEC
Filter
Reconstruction
CT Dose Index
CT dose index (CTDI) is the standardized
measure of the radiation output of a CT system,
Currently used measures are the CTDI100 and
CTDIw, modified to CTDIvol for modern helical
scanners. 
CTDI phantoms(PMMA)
Measurement of CTDI
• Ionisation pencil chamber
– Air-filled chamber
– X-rays cause ionisations in
chamber, causing current to
flow, proportional to exposure
– Instant readings, good
accuracy, easy to use
100 mm
Measurement of CTDI
• Single slice measurement
(z-axis)
Dose
T
Nominal
beam width
( )dzzD
T
1
CTDI
-
∫
+∞
∞
=
( )dzzD
T
1
CTDI
50
50-
100
∫
+
=
-50 +50
∫
+
−
=
50
50
D(z)dz
n.T
1
CTDI100
n = no. slices imaged simultaneously
T = nominal imaged width
Davge
T
100Davge
CTDI100
×
=
CTDI100
• CTDI100 is a measure of radiation dose on a 100mm
long pencil ionization chamber.
• Centre
• Periphery - 1 cm depth
(mean of 4 positions)
C
P1
P2
P3
P4
320 mm
‘Body’
‘Head’
160 mm
140
mm
Measurement of MSAD(Multiple Scan
Average Dose)
CTDI ≈ ‘Series’ dose
Multi-scan
‘Series’ dose
CTDI×
×
=
I
TN
MSAD
T
T is the nominal scan width (mm)
I is the distance between scans (mm)
I
N is the number of scans
N × T is the total nominal scan width
CTDI100
• Typical CTDI100 values (mGy)
40
Head
Body
40
4040
40
20
2020
20
10
Periphery : centre ≅ 1:1 Periphery : centre ≅ 2:1
Derivatives of CTDI100
• CTDIW
• Weighted average CTDI: represents the average
dose for contiguous irradiation
• CTDIw = 1/3 CTDI100,C + 2/3 CTDI100,P
CTDIC CTDIP
Derivatives of CTDI100
• CTDI100 & CTDIw refer to a pitch of 1
• Average absorbed dose dependent on pitch
Contiguous Extended Overlapping
CTDIvol
• Volume CTDI: Considers contiguous scanning
• CTDIvol = CTDIw
Pitch
Pitch = 1
CTDIvol = CTDIw
Pitch = 2
CTDIvol = CTDIw
2
Pitch = 0.5
CTDIvol = 2 x CTDIw
Radiation risk: DLP
• CTDIvol is a measure of absorbed dose, energy
absorbed per unit mass
• To measure radiation risk from stochastic effects
the total energy absorbed must be considered
• In CT this can be estimated using the Dose Length
Product, DLP
DLP = CTDIvol . L (mGy.cm)
DLP1 ≅ DLP2
where L = scan length
Dose length product
L1
T
Pitch 1
8 rotations
Pitch 2
8 rotations
L2
T
as CTDIvol2 = CTDIvol1
2
Estimates of effective dose (E)
• Can be obtained from DLP
• Effective dose = DLP. CF (mSv)
•
•
•
•
•
•
Conversion factors not scanner specific or location
specific
Region of body Conversion factor,EDLP
(mSv mGy-1
cm-1
)
Head & neck 0.0031
Head 0.0021
Neck 0.0059
Chest 0.014
Abdomen& pelvis 0.015
Trunk 0.015
CT dose reduction techniques
AEC systems have a number of
potential advantages, including better
control of patient radiation dose,
avoidance of photon starvation
artifacts, reduced load on the x-ray
tube, and the maintenance of image
quality in spite of different attenuation
values on CT scans
Types of AEC
Patient-Size AEC
Z-axis AEC
Rotational or Angular AEC
Operation of AEC Systems on
Different Multidetector CT Scanners
Exposure 3D
CARE Dose 4D
Patient-Size AECPatient size AEC: the tube current is adjusted
based on the overall size of the patient to reduce the
variation in image quality between small patients and
large patients. For a given patient size, the
appropriate milliamperage is selected and is used for
the entire examination or scan series
Hi-mA
Lo-mA
Z-axis AEC: tube current is modulated
according to patient attenuation along the z-
axis.The goal is to reduce the variation in image
quality of images from the same series.
attenuation
Patient-Size AECRotational AEC: The tube current is decreased
and increased rapidly (modulated) during the course
of each rotation to compensate for differences in
attenuation between lateral (left-right) and A-P
(anterior-posterior) projections .
highattenuationlow attenuation
Combination of AEC functions
• Tube current is adjusted during scanning to compensate for
attenuation differences – dose applied to patient only where
needed, avoiding dose where it isn’t
mA
position
On line’ modulation–uses attenuation data from previous rotation–
adapts tube current to patient attenuation ‘on the fly’
Scan projection radiographs (SPRs, known as scout,
scanogram or topogram views) are the main way that
AEC systems assess the attenuation of the patient in
order to set the tube current
To obtain correct attenuation data from SPR
always centre the patient carefully
Patient is positioned in the
isocenter –
optimal dose and image quality
Patient is positioned too high -
increased mAsPatient is positioned too low -
reduced mAs and increased noise
Toshiba:defining image quality
requirements
Specify s.d. level (or ‘image quality level)–patient
mAcalculated to achieve this noise level at any
scan parameter settings
Set min & max mA
Benefits of CT scanner
AEC
Consistent image quality
Potential for dose reduction
through
exposure optimisation
Reduced tube loading
Extended scan runs(OLP)
Reduction in photon starvation
artifact
30
• Images along length of phantom (no AEC)
•
•
•
•
•
•
•
•
Constant mA
Testing the AEC
31
Testing the AEC
• Measure noise with AEC off and on
• Monitor mA, CTDIvol
0
4
8
12
16
20
24
28
-150 -100 -50 0 50 100 150
Z-position (mm)
Noise(%)
automA off
Noise Index 12
Increased
mA
Decreased
mA
Constant mA
Same
mA
Increased
mA
Decreased
mA
32
Coronal view Sagittal view
z-axis
AEC off
z-axis
AEC on
Noise
increases
Constant
noise
Testing the AEC – Viewing with MPR
photon starvation artifact
without angular mA modulation with angular mA modulation
Bowtie Filter
Longer bowtie path lines up with shorter
patient path
Reduce x-ray scatter (noise and artifact)
Maintain uniform x-ray at detector
Reduce surface dose by 50%
• Retrospectively gated CCTA(dose modulation )
~15 mSv100%
20% ~30% reduction
Image obtained in middiastole
(75% of R-R interval)
reconstructed using 1.5-mm slice
thickness at high tube current
shows low-noise
Image obtained in midsystole
(30% of R-R interval)
reconstructed using 1.5-mm slice
thickness shows higher-noise
image obtained at low radiation
dose
• Prospectively gated CCTA
~ 1 mSv
Prospective Gating of CTA(snapshot plus)
40mm
5mm overlap
Scan range
Conventional technology
without Dose Shield
SOMATOM Definition AS+ with
Adaptive Dose Shield
Scan range
Dynamic Collimation
• In helical scanning extra rotations are needed at end of imaged
volume
– Significant extra dose: wide beam widths and short scans
• Dynamic collimation - collimator blades open and close
asymetrically at start and end of scan
(a) conventional and (b) adaptive section collimation CT scanning protocols. For
adaptive section collimation, shape of x-ray cone beam at beginning and end of spiral
acquisition is controlled by two collimators made of absorbent material.
Image reconstruction(FBP)
attenuation
detectorposition
90°2 projections4 projections8 projections16 projections
attenuation detector position
0°
0(3) 0(9)
0(7) 0(5)
6 6
6 6
10 14
12
12
12 12
5 7
5 7
3 9
7 5
3
5
9
7
816
12 12
+1-1
-2+2
Iterative reconstruction
Iterative reconstruction
120 kVp and 300 mA FBP
120 kVp and 300 mA ASiR 100%
120 kVp and 300 mA ASiR 50%
Dose reduction
Dose reduction

Dose reduction

  • 1.
    Radiation dose modulationand dose reduction techniques
  • 2.
    Introduction to presentation CTDose Index CTDI100 CTDIvol DLP Effective dose CT dose reduction techniques AEC Filter Reconstruction
  • 3.
    CT Dose Index CTdose index (CTDI) is the standardized measure of the radiation output of a CT system, Currently used measures are the CTDI100 and CTDIw, modified to CTDIvol for modern helical scanners. 
  • 4.
  • 6.
    Measurement of CTDI •Ionisation pencil chamber – Air-filled chamber – X-rays cause ionisations in chamber, causing current to flow, proportional to exposure – Instant readings, good accuracy, easy to use 100 mm
  • 7.
    Measurement of CTDI •Single slice measurement (z-axis) Dose T Nominal beam width ( )dzzD T 1 CTDI - ∫ +∞ ∞ = ( )dzzD T 1 CTDI 50 50- 100 ∫ + = -50 +50 ∫ + − = 50 50 D(z)dz n.T 1 CTDI100 n = no. slices imaged simultaneously T = nominal imaged width Davge T 100Davge CTDI100 × =
  • 8.
    CTDI100 • CTDI100 isa measure of radiation dose on a 100mm long pencil ionization chamber. • Centre • Periphery - 1 cm depth (mean of 4 positions) C P1 P2 P3 P4 320 mm ‘Body’ ‘Head’ 160 mm 140 mm
  • 9.
    Measurement of MSAD(MultipleScan Average Dose) CTDI ≈ ‘Series’ dose Multi-scan ‘Series’ dose CTDI× × = I TN MSAD T T is the nominal scan width (mm) I is the distance between scans (mm) I N is the number of scans N × T is the total nominal scan width
  • 10.
    CTDI100 • Typical CTDI100values (mGy) 40 Head Body 40 4040 40 20 2020 20 10 Periphery : centre ≅ 1:1 Periphery : centre ≅ 2:1
  • 11.
    Derivatives of CTDI100 •CTDIW • Weighted average CTDI: represents the average dose for contiguous irradiation • CTDIw = 1/3 CTDI100,C + 2/3 CTDI100,P CTDIC CTDIP
  • 12.
    Derivatives of CTDI100 •CTDI100 & CTDIw refer to a pitch of 1 • Average absorbed dose dependent on pitch Contiguous Extended Overlapping
  • 13.
    CTDIvol • Volume CTDI:Considers contiguous scanning • CTDIvol = CTDIw Pitch Pitch = 1 CTDIvol = CTDIw Pitch = 2 CTDIvol = CTDIw 2 Pitch = 0.5 CTDIvol = 2 x CTDIw
  • 14.
    Radiation risk: DLP •CTDIvol is a measure of absorbed dose, energy absorbed per unit mass • To measure radiation risk from stochastic effects the total energy absorbed must be considered • In CT this can be estimated using the Dose Length Product, DLP
  • 15.
    DLP = CTDIvol. L (mGy.cm) DLP1 ≅ DLP2 where L = scan length Dose length product L1 T Pitch 1 8 rotations Pitch 2 8 rotations L2 T as CTDIvol2 = CTDIvol1 2
  • 16.
    Estimates of effectivedose (E) • Can be obtained from DLP • Effective dose = DLP. CF (mSv) • • • • • • Conversion factors not scanner specific or location specific Region of body Conversion factor,EDLP (mSv mGy-1 cm-1 ) Head & neck 0.0031 Head 0.0021 Neck 0.0059 Chest 0.014 Abdomen& pelvis 0.015 Trunk 0.015
  • 17.
    CT dose reductiontechniques AEC systems have a number of potential advantages, including better control of patient radiation dose, avoidance of photon starvation artifacts, reduced load on the x-ray tube, and the maintenance of image quality in spite of different attenuation values on CT scans
  • 18.
    Types of AEC Patient-SizeAEC Z-axis AEC Rotational or Angular AEC Operation of AEC Systems on Different Multidetector CT Scanners Exposure 3D CARE Dose 4D
  • 19.
    Patient-Size AECPatient sizeAEC: the tube current is adjusted based on the overall size of the patient to reduce the variation in image quality between small patients and large patients. For a given patient size, the appropriate milliamperage is selected and is used for the entire examination or scan series Hi-mA Lo-mA
  • 20.
    Z-axis AEC: tubecurrent is modulated according to patient attenuation along the z- axis.The goal is to reduce the variation in image quality of images from the same series. attenuation
  • 21.
    Patient-Size AECRotational AEC:The tube current is decreased and increased rapidly (modulated) during the course of each rotation to compensate for differences in attenuation between lateral (left-right) and A-P (anterior-posterior) projections . highattenuationlow attenuation
  • 22.
    Combination of AECfunctions • Tube current is adjusted during scanning to compensate for attenuation differences – dose applied to patient only where needed, avoiding dose where it isn’t mA position
  • 23.
    On line’ modulation–usesattenuation data from previous rotation– adapts tube current to patient attenuation ‘on the fly’
  • 25.
    Scan projection radiographs(SPRs, known as scout, scanogram or topogram views) are the main way that AEC systems assess the attenuation of the patient in order to set the tube current
  • 26.
    To obtain correctattenuation data from SPR always centre the patient carefully Patient is positioned in the isocenter – optimal dose and image quality Patient is positioned too high - increased mAsPatient is positioned too low - reduced mAs and increased noise
  • 27.
    Toshiba:defining image quality requirements Specifys.d. level (or ‘image quality level)–patient mAcalculated to achieve this noise level at any scan parameter settings Set min & max mA
  • 28.
    Benefits of CTscanner AEC Consistent image quality Potential for dose reduction through exposure optimisation Reduced tube loading Extended scan runs(OLP) Reduction in photon starvation artifact
  • 30.
    30 • Images alonglength of phantom (no AEC) • • • • • • • • Constant mA Testing the AEC
  • 31.
    31 Testing the AEC •Measure noise with AEC off and on • Monitor mA, CTDIvol 0 4 8 12 16 20 24 28 -150 -100 -50 0 50 100 150 Z-position (mm) Noise(%) automA off Noise Index 12 Increased mA Decreased mA Constant mA Same mA Increased mA Decreased mA
  • 32.
    32 Coronal view Sagittalview z-axis AEC off z-axis AEC on Noise increases Constant noise Testing the AEC – Viewing with MPR
  • 34.
  • 35.
    without angular mAmodulation with angular mA modulation
  • 36.
    Bowtie Filter Longer bowtiepath lines up with shorter patient path
  • 37.
    Reduce x-ray scatter(noise and artifact) Maintain uniform x-ray at detector Reduce surface dose by 50%
  • 38.
    • Retrospectively gatedCCTA(dose modulation ) ~15 mSv100% 20% ~30% reduction
  • 39.
    Image obtained inmiddiastole (75% of R-R interval) reconstructed using 1.5-mm slice thickness at high tube current shows low-noise Image obtained in midsystole (30% of R-R interval) reconstructed using 1.5-mm slice thickness shows higher-noise image obtained at low radiation dose
  • 40.
    • Prospectively gatedCCTA ~ 1 mSv Prospective Gating of CTA(snapshot plus) 40mm 5mm overlap
  • 41.
    Scan range Conventional technology withoutDose Shield SOMATOM Definition AS+ with Adaptive Dose Shield Scan range Dynamic Collimation • In helical scanning extra rotations are needed at end of imaged volume – Significant extra dose: wide beam widths and short scans • Dynamic collimation - collimator blades open and close asymetrically at start and end of scan
  • 42.
    (a) conventional and(b) adaptive section collimation CT scanning protocols. For adaptive section collimation, shape of x-ray cone beam at beginning and end of spiral acquisition is controlled by two collimators made of absorbent material.
  • 43.
    Image reconstruction(FBP) attenuation detectorposition 90°2 projections4projections8 projections16 projections attenuation detector position 0°
  • 44.
    0(3) 0(9) 0(7) 0(5) 66 6 6 10 14 12 12 12 12 5 7 5 7 3 9 7 5 3 5 9 7 816 12 12 +1-1 -2+2 Iterative reconstruction
  • 46.
  • 47.
    120 kVp and300 mA FBP 120 kVp and 300 mA ASiR 100% 120 kVp and 300 mA ASiR 50%