1. Computed Tomography / Spiral Computed Tomography
2. Clinical and Principle Operation of Computed Tomography
3. Law and Regulation in Malaysia
4. Radiation Dose
This slide best explains the introduction of CT, basis and types of CT image reconstructions with detailed explanation about Interpolation, convolution, Fourier slice theorem, Fourier transformation and brief explanation about the image domain i.e digital image processing.
This slide best explains the introduction of CT, basis and types of CT image reconstructions with detailed explanation about Interpolation, convolution, Fourier slice theorem, Fourier transformation and brief explanation about the image domain i.e digital image processing.
CT scan and MRI are the techniques for body imaging. Computed Tomography or Computerized Axial Tomography is commonly referred to as a CT scan.
C- computed (Use of computer) and T- tomography (Greek word “Tomos” means “slice” and “Grapho” means “ To write”
The first commercial CT scanner was invented by Sir Godfrey Hounsfield in United Kingdom.
It is a diagnostic imaging procedure that uses a combination of X-rays and computer technology to produce images of the inside of the body. It shows detailed images of any part of the body including the bones, muscles, fat, organs and blood vessels.
CT scans may be performed to help diagnose tumors, investigate internal bleeding, or check for other internal injuries or damage.
Computed Tomography or Computerized Axial Tomography is commonly referred to as a CT scan.
C- computed (Use of computer) and T- tomography (Greek word “Tomos” means “slice” and “Grapho” means “ To write”
The first commercial CT scanner was invented by Sir Godfrey Hounsfield in United Kingdom.
It is a diagnostic imaging procedure that uses a combination of X-rays and computer technology to produce images of the inside of the body. It shows detailed images of any part of the body including the bones, muscles, fat, organs and blood vessels.
CT scans may be performed to help diagnose tumors, investigate internal bleeding, or check for other internal injuries or damage. Computed Tomography or Computerized Axial Tomography is commonly referred to as a CT scan.
C- computed (Use of computer) and T- tomography (Greek word “Tomos” means “slice” and “Grapho” means “ To write”
The first commercial CT scanner was invented by Sir Godfrey Hounsfield in United Kingdom.
It is a diagnostic imaging procedure that uses a combination of X-rays and computer technology to produce images of the inside of the body. It shows detailed images of any part of the body including the bones, muscles, fat, organs and blood vessels.
CT scans may be performed to help diagnose tumors, investigate internal bleeding, or check for other internal injuries or damage. MRI stands for Magentic Resonance Imaging which is a non-invasive medical imaging test that produces detailed images of almost every internal structure in the human body, including the organs, bones, muscles and blood vessels.
MRI scanners create images of the body using a large magnet and radio waves.
No ionizing radiation is produced during an MRI exam, unlike X-rays. These images give your physician important information in diagnosing your medical condition and planning a course of treatment.
Raymond Damadian, the inventor of the first magnetic resonance scanning machine performed the first full-body scan of a human being in 1977.
The Nobel Prize was awarded to the American chemist, Paul Lauterbur, and the British physicist, Peter Mansfield, for developing a method to represent the information gathered by a scanner as an image. This is fundamental for the way the technology is used today.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
2. Patient undergoing CT of the abdomen. Drawing shows
the patient on a table that slides through the CT
machine, which takes x-ray pictures of the inside of the
body.
3. INTRODUCTION
Computed Tomography is a well accepted imaging
modality for evaluation of the entire body.
Computed Tomography(CT) Scan Machines Uses X-
rays, a powerful form of Electromagnetic Radiation.
The images are obtained directly in the axial plane of
varying tissue thickness with the help of a computer.
Some pathology can be seen in saggital or coronal
plane by reconstruction of the images by computer.
CT has undergone several evolutions and nowadays
multi- detectors CT scanners have been evolved which
have better application in clinical field.
4. COMPARISION OF CT WITH
CONVIENTIONAL RADIOGRAPHY
Conventional radiography suffers from the collapsing
of 3D structures onto a 2D image.
CT gives accurate diagnostic information about the
distribution of structures inside the body.
5. COMPARISION OF CT WITH CONVIENTIONAL
RADIOGRAPHY.
A conventional X-ray image is basically a shadow.
Shadows give you an incomplete picture of an object's shape.
This is the basic idea of computer aided tomography. In a CT
scan machine, the X-ray beam moves all around the patient,
scanning from hundreds of different angles
6. Comparison of CT with
Conventional Radiography
Radiographic procedure is qualitative and not quantitative
7. ADVANTAGE OF COMPUTED
TOMOGRAPHY OVER CONVIENTIONA
RADIOGRAPHY.
To overcome superimposition of structures.
To improve contrast of the image.
To measure small differences in tissue
contrast.
8. TOMOGRAPHY
Imaging of Layer/Slice.
Principle
Images of structures lying above and below the plane
are blurred out due to motion unsharpness while the
structures lying in plane of interest appear sharp in in
the image.
10. PRINCIPLE OF COMPUTED
TOMOGRAPHY
The internal structure of the object can be
reconstructed from multiple projections of the
object.
Mathematically principle of CT was first developed in
1917 by Radon.
Proved that image of unknown object could be
produced if one had several number of projections
throughout the object.
11. VARIOUS PARAMETERS OF CT
• SLICE
• MATRIX
• PIXEL
• VOXE L
• CT NUMBER
• WINDOWING
• WINDOW WIDTH
• WINDOW LEVEL
• PITCH
12. SLICE/CUT
The cross section portion of body which is scanned for
production of CT image is called Slice.
The slice has width and therefore volume.
The width is determined by width of the x rays beam.
13. Cross Sectional Slices
Think like looking into the loaf of bread by cutting into
the thin slices and then viewing the slice individually.
14. MATRIX
The CT image is represented as the Matrix of the
number.
A two dimensional array of numbers arranged in rows
and columns is called Matrix.
Each number represent
the value of the image at
that location.
15. PIXEL
Each square in a matrix is called a pixel.
Also known as picture element.
16. VOXEL
Each individual element or number in the image
matrix represents a three dimensional volume element
in object called VOXEL.
17. CT NUMBER
The numbers in the image matrix is called CT
NUMBER.
Each pixel has a number
which represents the x-ray
attenuation in the
corresponding voxel of the
object.
18. HOUNSFIELD UNITS(HU)
Related to different composition and nature of Tissue.
The CT NUMBER is also known as Hounsfield
units(HU).
Represent the density of tissue.
Different Tissue have different CT number Range in
HU.
20. is a system where the CT no. range of interest is spread
cover the full grey scale available on the display system
Means total range of CT no. values selected for gray
scale interpretation. It corresponds to contrast of the
image.
represents the CT no. selected for the centre of the
range of the no. displayed on the image. It corresponds
to brightness of image .
21. Pitch
The relationship between patient and tube motion is
called Pitch.
It is defined as table movement during each
revolution of x-ray tube divided by collimation
width.
For example: For a 5mm section, if patient moves
10mm during the time it takes for the x-ray tube to
rotate through 360˚, the pitch is 2.
Increasing pitch reduces the scan time and patient
dose.
23. Phase of CT scanning
1.Scanning the patient or data Acquisition
a)X-ray Generator
b)X-ray Tube
c)X-ray Filtration System
d)Detector System
2.Reconstruction
a)Simple back projection
b)Iterative method
c)Analytical method
3.Display
24.
25. During CT Scan (Procedure)
1) Patient lie on a narrow, motorized table that slides through
the opening into a tunnel.
2) Straps and pillows may be used to help the patient to stay in
position. During a head scan, the table may be fitted with a
special cradle that holds patient's head still.
3) While the table moves patient into the scanner, detectors and
the X-ray tube rotate around the patient. Each rotation yields
several images of thin slices of the body.
4) A technologist in a separate room can see and hear the
patient. Patient able to communicate with the technologist
via intercom.
5) patient need to hold their breath at certain points to avoid
blurring the images.
26. How a CT system
works:
1. A motorized table moves the patient
through a circular opening in the
CT imaging system.
2. While the patient is inside the
opening, an X-ray source and a
detector assembly within the system
rotate around the patient. A single
rotation typically takes a second or
less. During rotation the X-ray
source produces a narrow, fan-
shaped beam of X-rays that passes
through a section of the patient's
body.
27. 3. Detectors in rows opposite the X-ray
source register the X-rays that pass
through the patient's body as a snapshot in
the process of creating an image. Many
different "snapshots" (at many angles
through the patient) are collected during
one complete rotation.
4. For each rotation of the X-ray source and
detector assembly, the image data are sent
to a computer to reconstruct all of the
individual "snapshots" into one or multiple
cross-sectional images (slices) of the
internal organs and tissues.
28. Fractures as seen on
a CT scan.
Source: James
Heilman, M.D.,
[CC-BY-SA-3.0]
29. Axial view shows the circular dissection
membrane in the aortic arch.
Dissection of the complete thoracic aorta
31. The entry was just at
the level of the aortic
root and extended via
the large ascending
aorta and the aortic
arch to all three
supra-aortic vessels
(brachiocephalic
trunk, carotid artery
and subclavian
artery).
Dissection of the complete thoracic aorta
32.
33. HELICAL CT
A technique where by the patient is transported
continuously through the gantry while data are
acquired continuously during several 360 degrees
scans.
Also k/a spiral or volume CT.
34. Advantages of helical CT
• Increased speed a study.
• Exact continuity of images.
• Less slice misregistration.
• Less motion artifact.
• Need for less contrast medium.
• Availability of volumetric data.
35. 1. Slip ring device
2. More efficient tube cooling
3. Increased milliampere capability
4. Smoother table movement
5. Software adjustment for table
movement
6. Efficient detectors
36. Is one of the important parts of spiral CT
machines.
Serves as a connection of the gantry rotating
part and the fixed portion of the power line
and the signal line.
38. Adjustment in reconstruction
algorithm
Interpolation algorithm
Estimation of a unknown value between known
values is called interpolation.
Estimation of a unknown value beyond known
values is called extrapolation.
39. Pitch: relation of table speed to slice
thickness Pitch= Table feed
* time per
rotation of 360
collimation
Pitch= Table feed , if it
is a 1 sec scan.
collimation
40. Limitations
• Requires very cooperative patient.
• Costly machine and X-ray tube.
• Loss of image resolution because of the interpolation
required to process data.
41.
42. RADIATION DOSE IN CT
Volume Computed Tomography Dose Index (CTDI ) is avol
standardized parameter to measure Scanner Radiation Output
CTDIvol provides information about the amount of radiation
used to perform the study.
CTDI is NOT patient dosevol
CTDI is reported in units of mGy for either a 16-cmvol
(for head exams) or 32-cm (for body exams) diameter.
AAPM (American Association of Physicts in Medicine)
introduces a parameter known as the Size Specific Dose
Estimate (SSDE) to allow estimation of patient dose based on
CTDI and patient size.vol
For the same CTDI , a smaller patient will tend to have avol
higher patient dose than a larger patient.