Digital Tomosynthesis (DT) is a new radiographic imaging technique that is revived from the nearly century-old traditional film-screen tomography. This rejuvenation is all made possible by the recent advances in high frame-rate, high-sensitivity flat-panel digital radiographic detector, rapid pulsed-exposure sequence-capable high-frequency x-ray generator, the widely available and low-cost computer GPU processing power, and the precision motion controls built in the digital radiography system hardware. Read the white paper.
EVP Plus Software delivers state-of-the-art image processing for CR and DR sy...Carestream
Radiographic technologists expect a high degree of
automation and efficiency in the technology they use in their
daily workflow, which means they expect minimal interaction
with the technology’s modality software. At the same time,
radiologists also need the flexibility to specify their site’s
individualized diagnostic viewing preferences. The CARESTREAM DirectView EVP Plus Software successfully
overcomes this challenge for digital-projection radiography.
EVP Plus automatically processes and delivers diagnostic-quality DR and CR images to PACS, based on look preferences that can be uniquely specified by each site.
Tube and Line and Pneumothorax Visualization SoftwareCarestream
Carestream has implemented companion views in its digital
radiography systems. A companion view is designed to
complement the standard processed radiographic image
delivered from the digital radiography capture modality to
PACS, to provide an additional rendering tailored for the visual
interpretation needed for a specific diagnostic or clinical
purpose. Two companion views are available in Carestream
products for chest radiography: one for the optimal
visualization of tubes and lines in chest radiographs
(CARESTREAM Tube & Line Visualization Software), and the
other for enhancing the conspicuity of a pneumothorax
(CARESTREAM Pneumothorax Visualization Software).
Bone Suppression for Chest Radiographic ImagesCarestream
Learn about Carestream's Bone Suppression Software and how it's used to aid in the detection of lung diseases.
For more information on Carestream's software solutions, please visit http://carestream.com/software
Smart Noise Cancellation Processing: New Level of Clarity in Digital RadiographyCarestream
Smart Noise Cancellation significantly reduces noise in diagnostic images while retaining fine spatial detail –there is no degradation of anatomical sharpness. When SNC is applied, it produces images that are significantly clearer than with standard processing. It also provides better contrast-to-noise ratio for images acquired at a broad range of exposures.
The CARESTREAM Touch Prime Ultrasound System presents a paradigm shift from these conventional approaches byemploying an all new system architecture that leverages integrated advanced GPU processing power and proprietaryparallel beamforming hardware.
For more information visit us at carestream.com
EVP Plus Software delivers state-of-the-art image processing for CR and DR sy...Carestream
Radiographic technologists expect a high degree of
automation and efficiency in the technology they use in their
daily workflow, which means they expect minimal interaction
with the technology’s modality software. At the same time,
radiologists also need the flexibility to specify their site’s
individualized diagnostic viewing preferences. The CARESTREAM DirectView EVP Plus Software successfully
overcomes this challenge for digital-projection radiography.
EVP Plus automatically processes and delivers diagnostic-quality DR and CR images to PACS, based on look preferences that can be uniquely specified by each site.
Tube and Line and Pneumothorax Visualization SoftwareCarestream
Carestream has implemented companion views in its digital
radiography systems. A companion view is designed to
complement the standard processed radiographic image
delivered from the digital radiography capture modality to
PACS, to provide an additional rendering tailored for the visual
interpretation needed for a specific diagnostic or clinical
purpose. Two companion views are available in Carestream
products for chest radiography: one for the optimal
visualization of tubes and lines in chest radiographs
(CARESTREAM Tube & Line Visualization Software), and the
other for enhancing the conspicuity of a pneumothorax
(CARESTREAM Pneumothorax Visualization Software).
Bone Suppression for Chest Radiographic ImagesCarestream
Learn about Carestream's Bone Suppression Software and how it's used to aid in the detection of lung diseases.
For more information on Carestream's software solutions, please visit http://carestream.com/software
Smart Noise Cancellation Processing: New Level of Clarity in Digital RadiographyCarestream
Smart Noise Cancellation significantly reduces noise in diagnostic images while retaining fine spatial detail –there is no degradation of anatomical sharpness. When SNC is applied, it produces images that are significantly clearer than with standard processing. It also provides better contrast-to-noise ratio for images acquired at a broad range of exposures.
The CARESTREAM Touch Prime Ultrasound System presents a paradigm shift from these conventional approaches byemploying an all new system architecture that leverages integrated advanced GPU processing power and proprietaryparallel beamforming hardware.
For more information visit us at carestream.com
An Ultrasound Image Despeckling Approach Based on Principle Component AnalysisCSCJournals
An approach based on principle component analysis (PCA) to filter out multiplicative noise from ultrasound images is presented in this paper. An image with speckle noise is segmented into small dyadic lengths, depending on the original size of the image, and the global covariance matrix is found. A projection matrix is then formed by selecting the maximum eigenvectors of the global covariance matrix. This projection matrix is used to filter speckle noise by projecting each segment into the signal subspace. The approach is based on the assumption that the signal and noise are independent and that the signal subspace is spanned by a subset of few principal eigenvectors. When applied on simulated and real ultrasound images, the proposed approach has outperformed some popular nonlinear denoising techniques such as 2D wavelets, 2D total variation filtering, and 2D anisotropic diffusion filtering in terms of edge preservation and maximum cleaning of speckle noise. It has also showed lower sensitivity to outliers resulting from the log transformation of the multiplicative noise.
Image Quality, Artifacts and it's Remedies in CT-Avinesh ShresthaAvinesh Shrestha
CT is one of the frequently used diagnostic imaging modalities in Radiology. Knowledge about image quality and artifacts is essential when diagnosing a patient with the help of CT images. Moreover, Radiology Technologist's should be very well aware about the ways to identify and eliminate or minimize the artifacts in CT for better image quality.
This slide best explains the introduction of CT, basis and types of CT image reconstructions with detailed explanation about Interpolation, convolution, Fourier slice theorem, Fourier transformation and brief explanation about the image domain i.e digital image processing.
Medical imaging technique is well advanced today and we are measuring signals from protons level in MRI imaging. But we left behind a error in 2-D measurement in digital X- ray in imaging. This we found out during imaging of Scanogram. In this presentation we are explaining that how we are controlling this error by applying small trick for given plane interest on the digital X-ray Scanogram image.
An Ultrasound Image Despeckling Approach Based on Principle Component AnalysisCSCJournals
An approach based on principle component analysis (PCA) to filter out multiplicative noise from ultrasound images is presented in this paper. An image with speckle noise is segmented into small dyadic lengths, depending on the original size of the image, and the global covariance matrix is found. A projection matrix is then formed by selecting the maximum eigenvectors of the global covariance matrix. This projection matrix is used to filter speckle noise by projecting each segment into the signal subspace. The approach is based on the assumption that the signal and noise are independent and that the signal subspace is spanned by a subset of few principal eigenvectors. When applied on simulated and real ultrasound images, the proposed approach has outperformed some popular nonlinear denoising techniques such as 2D wavelets, 2D total variation filtering, and 2D anisotropic diffusion filtering in terms of edge preservation and maximum cleaning of speckle noise. It has also showed lower sensitivity to outliers resulting from the log transformation of the multiplicative noise.
Image Quality, Artifacts and it's Remedies in CT-Avinesh ShresthaAvinesh Shrestha
CT is one of the frequently used diagnostic imaging modalities in Radiology. Knowledge about image quality and artifacts is essential when diagnosing a patient with the help of CT images. Moreover, Radiology Technologist's should be very well aware about the ways to identify and eliminate or minimize the artifacts in CT for better image quality.
This slide best explains the introduction of CT, basis and types of CT image reconstructions with detailed explanation about Interpolation, convolution, Fourier slice theorem, Fourier transformation and brief explanation about the image domain i.e digital image processing.
Medical imaging technique is well advanced today and we are measuring signals from protons level in MRI imaging. But we left behind a error in 2-D measurement in digital X- ray in imaging. This we found out during imaging of Scanogram. In this presentation we are explaining that how we are controlling this error by applying small trick for given plane interest on the digital X-ray Scanogram image.
In this paper, we present a novel iterative reconstruction algorithm for discrete tomography (DT) named total variation regularized discrete algebraic reconstruction technique (TVR-DART) with automated gray value estimation. This algorithm is more robust and automated than the original DART algorithm, and is aimed at imaging of objects consisting of only a few different material compositions, each corresponding to a different gray value in the reconstruction. By exploiting two types of prior knowledge of the scanned object simultaneously, TVR-DART solves the discrete reconstruction problem within an optimization framework inspired by compressive sensing to steer the current reconstruction toward a solution with the specified number of discrete gray values. The gray values and the thresholds are estimated as the reconstruction improves through iterations. Extensive experiments from simulated data, experimental μCT, and electron tomography data sets show that TVR-DART is capable of providing more accurate reconstruction than existing algorithms under noisy conditions from a small number of projection images and/or from a small angular range. Furthermore, the new algorithm requires less effort on parameter tuning compared with the original DART algorithm. With TVR-DART, we aim to provide the tomography society with an easy-to-use and robust algorithm for DT.
The CARESTREAM Tube and Grid Alignment System
provides better image quality and consistent
techniques for portable diagnostic radiography.
For more about Carestream's software solutions, visit http://carestream.com/software
High Speed and Area Efficient 2D DWT Processor Based Image Compressionsipij
This paper presents a high speed and area efficient DWT processor based design for Image Compression applications. In this proposed design, pipelined partially serial architecture has been used to enhance the speed along with optimal utilization and resources available on target FPGA. The proposed model has been designed and simulated using Simulink and System Generator blocks, synthesized with Xilinx Synthesis tool (XST) and implemented on Spartan 2 and 3 based XC2S100-5tq144 and XC3S500E-4fg320 target device. The results show that proposed design can operate at maximum frequency 231 MHz in case of Spartan 3 by consuming power of 117mW at 28 degree/c junction temperature. The result comparison has shown an improvement of 15% in speed.
A NOVEL ALGORITHM FOR IMAGE DENOISING USING DT-CWT sipij
This paper addresses image enhancement system consisting of image denoising technique based on Dual Tree Complex Wavelet Transform (DT-CWT) . The proposed algorithm at the outset models the noisy remote sensing image (NRSI) statistically by aptly amalgamating the structural features and textures from it. This statistical model is decomposed using DTCWT with Tap-10 or length-10 filter banks based on
Farras wavelet implementation and sub band coefficients are suitably modeled to denoise with a method which is efficiently organized by combining the clustering techniques with soft thresholding - softclustering technique. The clustering techniques classify the noisy and image pixels based on the
neighborhood connected component analysis(CCA), connected pixel analysis and inter-pixel intensity variance (IPIV) and calculate an appropriate threshold value for noise removal. This threshold value is used with soft thresholding technique to denoise the image .Experimental results shows that that the
proposed technique outperforms the conventional and state-of-the-art techniques .It is also evaluated that the denoised images using DTCWT (Dual Tree Complex Wavelet Transform) is better balance between smoothness and accuracy than the DWT.. We used the PSNR (Peak Signal to Noise Ratio) along with
RMSE to assess the quality of denoised images.
Contourlet Transform Based Method For Medical Image DenoisingCSCJournals
Noise is an important factor of the medical image quality, because the high noise of medical imaging will not give us the useful information of the medical diagnosis. Basically, medical diagnosis is based on normal or abnormal information provided diagnose conclusion. In this paper, we proposed a denoising algorithm based on Contourlet transform for medical images. Contourlet transform is an extension of the wavelet transform in two dimensions using the multiscale and directional filter banks. The Contourlet transform has the advantages of multiscale and time-frequency-localization properties of wavelets, but also provides a high degree of directionality. For verifying the denoising performance of the Contourlet transform, two kinds of noise are added into our samples; Gaussian noise and speckle noise. Soft thresholding value for the Contourlet coefficients of noisy image is computed. Finally, the experimental results of proposed algorithm are compared with the results of wavelet transform. We found that the proposed algorithm has achieved acceptable results compared with those achieved by wavelet transform.
3-D WAVELET CODEC (COMPRESSION/DECOMPRESSION) FOR 3-D MEDICAL IMAGESijitcs
Compression is an important part in image processing in order to save memory space and reduce the
bandwidth while transmitting. The main purpose of this paper is to analyse the performance of 3-D wavelet
encoders using 3-D medical images. Four wavelet transforms, namely, Daubechies 4,Daubechies
6,Cohen-Daubechies-Feauveau 9/7 and Cohen Daubechies-Feauveau5/3 are used in the first stage with
encoders such as 3-D SPIHT,3-D SPECK and 3-D BISK used in the second stage for the compression.
Experiments are performed using medical test image such as magnetic resonance images (MRI) and X-ray
angiograms (XA). The XA and MR image slices are grouped into 4, 8 and 16 slices and the wavelet
transforms and encoding schemes are applied to identify the best wavelet encoder combination. The
performances of the proposed scheme are evaluated in terms of peak signal to noise ratio and bit rate.
International Journal of Engineering and Science Invention (IJESI) is an international journal intended for professionals and researchers in all fields of computer science and electronics. IJESI publishes research articles and reviews within the whole field Engineering Science and Technology, new teaching methods, assessment, validation and the impact of new technologies and it will continue to provide information on the latest trends and developments in this ever-expanding subject. The publications of papers are selected through double peer reviewed to ensure originality, relevance, and readability. The articles published in our journal can be accessed online.
International Journal of Engineering Research and Applications (IJERA) is an open access online peer reviewed international journal that publishes research and review articles in the fields of Computer Science, Neural Networks, Electrical Engineering, Software Engineering, Information Technology, Mechanical Engineering, Chemical Engineering, Plastic Engineering, Food Technology, Textile Engineering, Nano Technology & science, Power Electronics, Electronics & Communication Engineering, Computational mathematics, Image processing, Civil Engineering, Structural Engineering, Environmental Engineering, VLSI Testing & Low Power VLSI Design etc.
Affordable Digital Upgrade for Medical Imaging - the Benefits and the Return ...Carestream
s your imaging facility using analog X-ray film and chemistry? Do you want to improve workflow and image quality - and save costs? Watch this informative presentation that explains the improvements in workflow and image quality, and shares results from an independent study by NHS UK on the measurable results in productivity. You can learn more about Carestream's affordable digital upgrade solutions here https://www.carestream.com/en/us/medical/dr-systems/mobile-x-ray/dr-retrofit-solutions #analogtodigital #digitalupgrade #affordabledigitalimaging #crtodr #medicalimaging #xrayimaging #diagnosticimaging #carestreamtalks
Dose Efficient Dual Energy Subtraction Radiography - Theory of OperationsCarestream
Dual energy digital radiography is an imaging technique that takes advantage of the differential, energy-dependent absorption properties of bone and soft tissue structures in human anatomy. By capturing two radiographic images of a patient in rapid succession, one at a relatively lower energy X-ray exposure and a second at a relatively higher energy, it is possible to mathematically derive a soft tissue-only image with bone structures removed, and a corresponding bone-only image. Read the white paper.
Special Report: Challenges and Solutions in Pediatric X-rayCarestream
Now more than ever, there is widespread focus on
the level of radiation received by pediatric patients
during imaging. In this special report, we explore both the challenges and potential solutions in contemporary pediatric imaging.
Special Report: Getting the Optimal Return on X-ray EquipmentCarestream
Radiology administrators need to meticulously analyze their spending to get the best possible return on their investment in medical imaging equipment. In this special report, we explore several approaches to get the maximum return on this important capital investment.
The Pursuit of Excellence in Image QualityCarestream
The accuracy of a medical diagnosis can only be as solid as the quality of the X-ray images. In this special report, we look at several ways that imaging facilities can improve their ability to capture pristine radiographs.
Whitepaper: Healthcare Data Migration - Top 10 Questions Carestream
Healthcare data migration is a challenging and critical undertaking. What do IT managers need to know before getting started? Read our white paper on the top 10 questions – and answers – you need to know before starting a healthcare data migration.
Whitepaper: Image Quality Impact of SmartGrid Processing in Bedside Chest Ima...Carestream
Scattered radiation is known to degrade image quality in
diagnostic X-ray imaging. A new image processing tool, SmartGrid, has been developed that compensates for the effects of X-ray scatter in an image, and produces results comparable to those of a physical antiscatter grid. Read the white paper to learn more.
La Sociedad Española de Radiología Médica (SERAM) ha publicado recientemente el documento “Guía para la renovación y actualización tecnológica en radiología”, en el que se hace un análisis de la situación de los equipos de imagen médica en España.
When evaluating cloud-based services, no issue is more
critical than data security. Cloud-based services today can
be compared to internet banking. Consumers were initially
afraid that online banking would make them more vulnerable
to fraud or identity theft. But as online security technologies
and processes have improved, online banking is now
actually safer than getting paper statements in the mail.
Sunway Medical Centre Installs CARESTREAM Vue PACS to Streamline Imaging Proc...Carestream
Sunway Medical Centre in Malaysia replaced its legacy solution with a CARESTREAM Vue PACS to gain new innovative features and functionality. The radiology department is using Vue PACS to help provide better patient care,
enhance clinical accuracy, and improve productivity.
White Paper: The Benefits of Mobile X-rays in Thoracic and Cardiac CareCarestream
Liverpool Heart & Chest Hospital authored this study/article on the indications and common problems for performing mobile chest radiography, the benefits of using CARESTREAM DRX-Revolution digital mobile machines, and the importance of using a structured technique to achieve an optimum mobile chest image. It also explores the hybrid examination currently utilised at LHCH in performing PA mobile chest radiographs on thoracic patients in the ward environment. For more information on CARESTREAM's mobile x-ray systems, visit http://www.carestream.com/motion-mobile/
Study: University Clinic, Regensburg, Evaluates Smart Flow in UltrasoundCarestream
The University Clinic, Regensburg, evaluated the Touch Prime Ultrasound System's Smart Flow technology and its touch screen user interface. The university documented Improvements in presentation of flow, and ease of functionality.
Financial Implications for Integrating Carestream OnSight 3D Extremity System...Carestream
Carestream Health commissioned a working group of surgeons and administrators from four leading orthopedic practices to
evaluate the clinical application and economic impact of the OnSight 3D Extremity System. This paper outlines the results of that working group’s findings, including specific economic models for practices of various sizes and throughputs.
To improve value and minimize patient exposure to ionizing
radiation, healthcare providers’ use of medical imaging must
be prudent and appropriate. The cornerstone of value-based
imaging is technology that provides broad access to patient
reports and images, enhancing communications among
physicians and with the patient while protecting patient data.
This is the role of the enterprise viewer. www.carestream.com/motion
Evaluating Enterprise Clinical Data-Management Systems at RSNA 2016Carestream
What are the essential capabilities to look for in an enterprise imaging system? It's complicated, but Carestream can help. Download and complete this checklist to rate each system you're considering. Then bring it to the Carestream booth in the South Hall at RSNA2016. We'll have a conversation over a fresh cup of coffee.
3 Reasons to Visit Carestream at RSNA2016 #RNSA16Carestream
Going to RSNA 2016? Here's three reasons why radiologists and health IT professionals will find it worthwhile to visit Carestream's booth in the South Hall at the show.
Whitepaper: Leveraging the Cloud to Enhance an Enterprise Imaging StrategyCarestream
What is the cloud's future in imaging?
Enterprise imaging strategies are front and center in healthcare IT these days. The increasing sophistication of imaging technology has resulted in substantial increases in imaging data. The upside of this increase is that clinicians have more imaging information available to aid in diagnosis and treatment. www.carestream.com/cloud
Empowering ACOs: Leveraging Quality Management Tools for MIPS and BeyondHealth Catalyst
Join us as we delve into the crucial realm of quality reporting for MSSP (Medicare Shared Savings Program) Accountable Care Organizations (ACOs).
In this session, we will explore how a robust quality management solution can empower your organization to meet regulatory requirements and improve processes for MIPS reporting and internal quality programs. Learn how our MeasureAble application enables compliance and fosters continuous improvement.
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdfSachin Sharma
Pediatric nurses play a vital role in the health and well-being of children. Their responsibilities are wide-ranging, and their objectives can be categorized into several key areas:
1. Direct Patient Care:
Objective: Provide comprehensive and compassionate care to infants, children, and adolescents in various healthcare settings (hospitals, clinics, etc.).
This includes tasks like:
Monitoring vital signs and physical condition.
Administering medications and treatments.
Performing procedures as directed by doctors.
Assisting with daily living activities (bathing, feeding).
Providing emotional support and pain management.
2. Health Promotion and Education:
Objective: Promote healthy behaviors and educate children, families, and communities about preventive healthcare.
This includes tasks like:
Administering vaccinations.
Providing education on nutrition, hygiene, and development.
Offering breastfeeding and childbirth support.
Counseling families on safety and injury prevention.
3. Collaboration and Advocacy:
Objective: Collaborate effectively with doctors, social workers, therapists, and other healthcare professionals to ensure coordinated care for children.
Objective: Advocate for the rights and best interests of their patients, especially when children cannot speak for themselves.
This includes tasks like:
Communicating effectively with healthcare teams.
Identifying and addressing potential risks to child welfare.
Educating families about their child's condition and treatment options.
4. Professional Development and Research:
Objective: Stay up-to-date on the latest advancements in pediatric healthcare through continuing education and research.
Objective: Contribute to improving the quality of care for children by participating in research initiatives.
This includes tasks like:
Attending workshops and conferences on pediatric nursing.
Participating in clinical trials related to child health.
Implementing evidence-based practices into their daily routines.
By fulfilling these objectives, pediatric nurses play a crucial role in ensuring the optimal health and well-being of children throughout all stages of their development.
Global launch of the Healthy Ageing and Prevention Index 2nd wave – alongside...ILC- UK
The Healthy Ageing and Prevention Index is an online tool created by ILC that ranks countries on six metrics including, life span, health span, work span, income, environmental performance, and happiness. The Index helps us understand how well countries have adapted to longevity and inform decision makers on what must be done to maximise the economic benefits that comes with living well for longer.
Alongside the 77th World Health Assembly in Geneva on 28 May 2024, we launched the second version of our Index, allowing us to track progress and give new insights into what needs to be done to keep populations healthier for longer.
The speakers included:
Professor Orazio Schillaci, Minister of Health, Italy
Dr Hans Groth, Chairman of the Board, World Demographic & Ageing Forum
Professor Ilona Kickbusch, Founder and Chair, Global Health Centre, Geneva Graduate Institute and co-chair, World Health Summit Council
Dr Natasha Azzopardi Muscat, Director, Country Health Policies and Systems Division, World Health Organisation EURO
Dr Marta Lomazzi, Executive Manager, World Federation of Public Health Associations
Dr Shyam Bishen, Head, Centre for Health and Healthcare and Member of the Executive Committee, World Economic Forum
Dr Karin Tegmark Wisell, Director General, Public Health Agency of Sweden
CHAPTER 1 SEMESTER V PREVENTIVE-PEDIATRICS.pdfSachin Sharma
This content provides an overview of preventive pediatrics. It defines preventive pediatrics as preventing disease and promoting children's physical, mental, and social well-being to achieve positive health. It discusses antenatal, postnatal, and social preventive pediatrics. It also covers various child health programs like immunization, breastfeeding, ICDS, and the roles of organizations like WHO, UNICEF, and nurses in preventive pediatrics.
Medical Technology Tackles New Health Care Demand - Research Report - March 2...pchutichetpong
M Capital Group (“MCG”) predicts that with, against, despite, and even without the global pandemic, the medical technology (MedTech) industry shows signs of continuous healthy growth, driven by smaller, faster, and cheaper devices, growing demand for home-based applications, technological innovation, strategic acquisitions, investments, and SPAC listings. MCG predicts that this should reflects itself in annual growth of over 6%, well beyond 2028.
According to Chris Mouchabhani, Managing Partner at M Capital Group, “Despite all economic scenarios that one may consider, beyond overall economic shocks, medical technology should remain one of the most promising and robust sectors over the short to medium term and well beyond 2028.”
There is a movement towards home-based care for the elderly, next generation scanning and MRI devices, wearable technology, artificial intelligence incorporation, and online connectivity. Experts also see a focus on predictive, preventive, personalized, participatory, and precision medicine, with rising levels of integration of home care and technological innovation.
The average cost of treatment has been rising across the board, creating additional financial burdens to governments, healthcare providers and insurance companies. According to MCG, cost-per-inpatient-stay in the United States alone rose on average annually by over 13% between 2014 to 2021, leading MedTech to focus research efforts on optimized medical equipment at lower price points, whilst emphasizing portability and ease of use. Namely, 46% of the 1,008 medical technology companies in the 2021 MedTech Innovator (“MTI”) database are focusing on prevention, wellness, detection, or diagnosis, signaling a clear push for preventive care to also tackle costs.
In addition, there has also been a lasting impact on consumer and medical demand for home care, supported by the pandemic. Lockdowns, closure of care facilities, and healthcare systems subjected to capacity pressure, accelerated demand away from traditional inpatient care. Now, outpatient care solutions are driving industry production, with nearly 70% of recent diagnostics start-up companies producing products in areas such as ambulatory clinics, at-home care, and self-administered diagnostics.
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ICH Guidelines for Pharmacovigilance.pdfNEHA GUPTA
The "ICH Guidelines for Pharmacovigilance" PDF provides a comprehensive overview of the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) guidelines related to pharmacovigilance. These guidelines aim to ensure that drugs are safe and effective for patients by monitoring and assessing adverse effects, ensuring proper reporting systems, and improving risk management practices. The document is essential for professionals in the pharmaceutical industry, regulatory authorities, and healthcare providers, offering detailed procedures and standards for pharmacovigilance activities to enhance drug safety and protect public health.
India Diagnostic Labs Market: Dynamics, Key Players, and Industry Projections...Kumar Satyam
According to the TechSci Research report titled “India Diagnostic Labs Market Industry Size, Share, Trends, Competition, Opportunity, and Forecast, 2019-2029,” the India Diagnostic Labs Market was valued at USD 16,471.21 million in 2023 and is projected to grow at an impressive compound annual growth rate (CAGR) of 11.55% through 2029. This significant growth can be attributed to various factors, including collaborations and partnerships among leading companies, the expansion of diagnostic chains, and increasing accessibility to diagnostic services across the country. This comprehensive report delves into the market dynamics, recent trends, drivers, competitive landscape, and benefits of the research report, providing a detailed analysis of the India Diagnostic Labs Market.
Collaborations and Partnerships
Collaborations and partnerships among leading companies play a pivotal role in driving the growth of the India Diagnostic Labs Market. These strategic alliances allow companies to merge their expertise, strengthen their market positions, and offer innovative solutions. By combining resources, companies can enhance their research and development capabilities, expand their product portfolios, and improve their distribution networks. These collaborations also facilitate the sharing of technological advancements and best practices, contributing to the overall growth of the market.
Expansion of Diagnostic Chains
The expansion of diagnostic chains is a driving force behind the growing demand for diagnostic lab services. Diagnostic chains often establish multiple laboratories and diagnostic centers in various cities and regions, including urban and rural areas. This expanded network makes diagnostic services more accessible to a larger portion of the population, addressing healthcare disparities and reaching underserved populations. The presence of diagnostic chain facilities in multiple locations within a city or region provides convenience for patients, reducing travel time and effort. A broader network of labs often leads to reduced waiting times for appointments and sample collection, ensuring that patients receive timely and efficient diagnostic services.
Rising Prevalence of Chronic Diseases
The increasing prevalence of chronic diseases is a significant driver for the demand for diagnostic lab services. Chronic conditions such as diabetes, cardiovascular diseases, and cancer require regular monitoring and diagnostic testing for effective management. The rise in chronic diseases necessitates the use of advanced diagnostic tools and technologies, driving the growth of the diagnostic labs market. Additionally, early diagnosis and timely intervention are crucial for managing chronic diseases, further boosting the demand for diagnostic lab services.
How many patients does case series should have In comparison to case reports.pdfpubrica101
Pubrica’s team of researchers and writers create scientific and medical research articles, which may be important resources for authors and practitioners. Pubrica medical writers assist you in creating and revising the introduction by alerting the reader to gaps in the chosen study subject. Our professionals understand the order in which the hypothesis topic is followed by the broad subject, the issue, and the backdrop.
https://pubrica.com/academy/case-study-or-series/how-many-patients-does-case-series-should-have-in-comparison-to-case-reports/
Navigating Challenges: Mental Health, Legislation, and the Prison System in B...Guillermo Rivera
This conference will delve into the intricate intersections between mental health, legal frameworks, and the prison system in Bolivia. It aims to provide a comprehensive overview of the current challenges faced by mental health professionals working within the legislative and correctional landscapes. Topics of discussion will include the prevalence and impact of mental health issues among the incarcerated population, the effectiveness of existing mental health policies and legislation, and potential reforms to enhance the mental health support system within prisons.
The Importance of Community Nursing Care.pdfAD Healthcare
NDIS and Community 24/7 Nursing Care is a specific type of support that may be provided under the NDIS for individuals with complex medical needs who require ongoing nursing care in a community setting, such as their home or a supported accommodation facility.
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Digital Tomosynthesis: Theory of Operation
1. White Paper | DRX-Evolution Plus Digital Radiography System
Technical Brief Series
Digital Tomosynthesis – Theory of Operation
Pending FDA 510(k) clearance
Author: Xiahui (Ed) Wang
Digital Tomosynthesis (DT) is a new radiographic imaging
technique that is revived from the nearly century-old traditional
film-screen tomography. This rejuvenation is all made possible
by the recent advances in high frame-rate, high-sensitivity flat-
panel digital radiographic detector, rapid pulsed-exposure
sequence-capable high-frequency x-ray generator, the widely
available and low-cost computer GPU processing power, and
the precision motion controls built in the digital radiography
system hardware.
Figure 1: An example of DT acquisition. Both wall stand and
table positions are supported by the Carestream DT option.
Carestream Health implements the DT functionality as an
upgradable option on the standard DRX-Evolution Plus Digital
Radiography System (Figure 1). The portable DRXPlus detector
can be placed inside either the wall bucky or the table bucky to
accommodate different exam types and positions.
The major benefit of DT over the traditional film-screen
tomography is that DT greatly simplifies the operator’s
workflow by separating the process of DT exposure acquisition
from image volume formation; it needs only a single sweep of
x-ray exposures and then relies on computer software in post-
processing to generate as many DT slices as needed at any slice
thickness and slice interval.
Background in Traditional Tomography
The traditional tomography acquisition uses synchronized,
reciprocal mechanical motion of the x-ray source and the film
cassette combined with a single, long-duration, continuous x-
ray exposure. Many scan patterns have been developed for the
x-ray source and cassette motion, such as linear, circular,
elliptical, spiral, hypocycloidal, etc., but linear motion is the
most frequently used in practice due to its simplicity.
Figure 2 illustrates how linear tomography works. Before a
tomography procedure, the operator visually estimates the
midline of the anatomical area of interest, determines the slice
thickness requirement for the exam, and then sets the initial
pivot level (fulcral plane) and the sweep angle for the
tomography scan accordingly.
For each tomographic scan the anatomical details in the fulcral
plane (e.g., object O in Figure 2) will be preserved while those
anatomical clutters above or below the fulcral plane will be
blurred or smeared (e.g., object X in Figure 2). The larger the
sweep angle, the more blurred the anatomical clutters
become. As anatomy clutter is the primary source of noise for
radiography, tomography isolates the anatomy of interest in
the fulcral plane from the unwanted clutters from the rest of
the anatomy, and therefore improves contrast-to-noise ratio of
the image details.
Each tomography acquisition uses one single continuous x-ray
exposure, and many acquisitions are frequently needed in
order to cover the anatomical area of interest fully. This would
definitely increase the overall exam time and the total radiation
dose by the total number of scans. As the overall exam time
and the total radiation dose must be limited, the number of
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tomographic scans is limited, which may limit the smallest
tomographic slice interval (slice pitch) and the spatial resolution
in the depth direction of the tomography volume.
Digital Tomosynthesis
Figure 3(a) illustrated how DT acquisition works. DT operates
based on the same principle as tomography except the
detector can either be mechanically motorized in
synchronization with the x-ray source or simply be stationary
during the exam. The DT implemented by Carestream chooses
to use stationary x-ray detector for the purpose of reducing
motion blur and improving spatial resolution. In addition, DT
uses multiple, low-power, pulsed x-ray exposures instead of a
single continuous exposure. Correspondingly the x-ray detector
in a DT exam will capture each short x-ray pulse as individual
images from different projection angles of the x-ray source.
These projections are used to reconstruct a stack of DT slices
for viewing, of which each slice is equivalent to a traditional
tomogram with fulcral plane set at the center of the DT slice.
Because the image acquisition is separated from the DT image
volume formation process, sophisticated reconstruction
processes are used to maximize the anatomy contrast-to-noise
ratio in the DT slices. Figure 3(b) and (c) shows the “Shift-and-
Add” method used in some of the early DT systems.
Individually captured images are shifted differently and added
Figure 3: Schematic view of DT acquisition (a) and reconstructions of slices at different depth (b) (c).
O
X
X-Ray Source
Motion
O X
X O
X
O
X X X
O
O
O
O X
X O
X
O
O O
X
X
X
O
(a) (b) (c)
Stationary
Detector
Plane A
Plane B
Plane A
Reconstruction
Plane B
Reconstruction
Figure 2: In traditional tomographic imaging, object structure
details (e.g., Object O) in the fulcral plane stays focused
(stationary in the film plane) while objects outside the focal
plane (e.g., object X) become blurred or smeared due to
motion.
O
X
O X X O
O
X
Focal Plane
X-Ray Source
Motion
Synchronized
Detector Motion
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together in the software to generate DT slices focused at
different depths of the anatomy. The Carestream DT
reconstruction software leverages the state-of-the-art
algorithms that are the same in principle to those applied in
the computed tomography (CT), such as filtered back
projection or iterative reconstruction. As a consequence, the
anatomical details are greatly improved with DT when
compared to tomogram. Figure 4 shows two DT slices of the
pelvis region at different depth locations.
The exam time is greatly reduced with DT than with traditional
tomography, and the operator’s trial-and-error process in
locating the anatomical region of interest is eliminated.
Multiple projections are acquired during a single DT acquisition
sweep. Afterward the anatomical features at different depth
locations are reconstructed mathematically. The total number
of slices and the slice interval can be made arbitrarily large or
small in the software as needed; and they are limited by only
the computer memory capacity, network bandwidth, PACS
storage space, and most importantly the diagnostic needs on
the image resolution.
DT Scout
Each DT acquisition sequence starts with a scout view. The
scout serves two purposes for DT: 1) collimation and anatomy
positioning, and 2) exposure control. The scout view is
captured at the same technique settings (kVp, mAs, etc.) as
with a standard radiography except the projection angle is
always straight on to the detector center and the SID is fixed
(110 cm for table and 180 cm for wall stand). The scout is
processed as a radiographic image and then presented to the
operator to verify the collimation for anatomy coverage as well
as the anatomy positioning. The scout image can be captured
using either automatic exposure control (AEC) or manual
technique settings. The operator would decide on the
appropriateness of the image quality of the scout view for
diagnosis or retake the exposure if adjustment is needed.
DT Sequence Exposure Control
Once the DT scout is captured and accepted by the operator,
its exposure technique will be used as the basis to derive the
total exposure for the DT sequence. This is an important
Figure 4: DT slice examples of the pelvis region at different depth locations.
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operation step for automatic exposure control of the DT
sequence.
The total exposure level, mAs in particular, of a DT sequence is
set as the multiplication of the DT scout exposure level (mAs)
and the DT Technique Scale Factor that is preconfigured in the
Preference Editor. This is regardless of the total number of
projections and the x-ray tube sweep angle specified. The total
DT mAs is allocated equally to all the DT projections. The other
exposure technique settings between the scout and the DT
sequence, such as kVp and beam filtration, are kept the same.
DT Acquisition Modes and Reconstruction
Resolution
DT projection images can be acquired in either high-resolution
(HR) mode or high-speed (HS) mode. In the HR acquisition
mode, the detector works in its native resolution (i.e., no pixel
binning) and acquires images at 4.5 frames per second (fps); in
the HS acquisition mode the detector uses 2x1 pixel binning
and acquires images at 9.0 fps due to 50% reduced data rate.
The primary usage of the HR mode is for musculoskeletal
exams (hand, foot, knee, etc.), when the patient motion
artifact due to the longer acquisition time is limited and it
would not be a major concern to the DT image quality. The
improved frame rate in the HS acquisition mode is directly
translated into 50% reduction in total DT image acquisition
time. Because the HS acquisition mode is 2X faster, it will be
helpful to reduce the patient motion artifact. There is a
potential image resolution loss due to 2x1 pixel binning;
however, the impact is minimized in the system design by
binning the pixels in the x-ray tube motion direction as well as
applying sharpness enhancement filtering operation to
compensate for the minor resolution loss. A comparative
image quality example is shown in Figure 5.
Regardless of the acquisition mode, DT slices can be
reconstructed and presented in two spatial resolutions during
post processing: the native 1x1 pixel resolution (HR-res) or the
2x2 pixel average resolution (STD-res). The size of an STD-res
DT volumetric image will be 1/8 (½ x ½ x ½) of that of the
corresponding HR-res image.
In summary, the DT volumetric images can be generated in
four combinations (see Table 1 for the recommended
applications). In theory, the HR/HR-res combination will offer
the best spatial resolution in the reconstructed DT slice image
because both the detector and the reconstruction work in the
native 1x1 resolution.
Figure 5: Image quality comparison of a hand phantom acquired in HR mode (left) and HS mode (right). Both images are
reconstructed in HR-res using 0.3 cm slice thickness and 0.05 cm slice interval. Sharpness enhancement is applied automatically in
the software to bring up the anatomical details in the image acquired in HS mode.
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HR Std. Res
Acquisition
HR (1x1)
Hand/Wrist
Foot/Ankle
Knee
Shoulder
Acquisition
HS (1x2)
Hand/Wrist
Foot/Ankle
Knee
Shoulder
Chest
Abdomen
Pelvis
C-Spine
Table 1: Recommended DT operation for different exam types.
HR-res reconstruction is optimal for musculoskeletal exams,
and the HS acquisition helps to reduce patient motion artifact.
DT Section Thickness and Sweep Angle α
As mentioned before, DT imaging follows the same principles
as traditional tomography. For any anatomical details that are
outside the fulcral plane, the greater the sweep angle, the
greater the blur effect. Because all the details in the fulcral
plane are unchanged, increasing the sweep angle effectively
reduces the clutter caused by anything that is outside the
fulcral plane, which makes the tomographic slice appear
“thinner.” In practice, because the anatomical details gradually
become blurrier as their distance from the fulcral plane
increases, Section Thickness is used to define the region of the
anatomy within which all the anatomical details are under a
permissible blur level. Section Thickness is a value that is
determined solely by the acquisition geometry and therefore is
inherent to the acquisition. It is different from and should not
be confused with the Slice Thickness used in the DT
reconstruction. Table 2 shows the pre-calculated section
thickness at different sweep angles α and 0.25 mm permissible
blur values.
Sweep Angle α
(Degrees)
Section
Thickness (mm)
10 2.86
15 1.90
20 1.42
25 1.13
30 0.93
35 0.79
40 0.69
Table 2: Look up table for selecting DT sweep angle to achieve
desired slice thickness, assuming the maximum permissible blur
is 0.25 mm.
DT Slice Thickness t and Slice Interval δ
The DT image is presented as a stack of reconstructed 2D
coronal slices. The center location of each slice corresponds to
the fulcral plane at which anatomical details are maximized.
The distance between the reconstruction slices is the slice
interval (δ). The smaller the δ value, the finer the DT
reconstruction resolution in the depth direction. The slice
interval can be set accordingly by the operator, depending on
the requirements on the anatomical features to be visualized
for diagnosis. For example, for small musculoskeletal exams
such as wrist, etc., the δ value can be set between 0.5 mm to
1.0 mm, and for chest exams between 1.0 mm to 2.0 mm.
Each DT slice covers a slab of anatomical region and its
thickness (t) can be made arbitrarily by the DT reconstruction
algorithm, which is independent of (i.e., decoupled from) the
Section Thickness or the slice interval (δ). In practice the
reconstruction slice thickness (t) should always be greater than
or equal to the slice interval such that no anatomical void is
created (see Figure 6), causing the slices to overlap each other
partially. A smaller t value more likely helps to resolve the
anatomical details better but at the potential expense of
greater noise appearance. On the other hand, greater t value
helps to reduce the image noise but potentially blends more
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anatomical details from the region outside the fulcral plane
therefore defeating the purpose of DT. A default slice
thickness of 20.0 mm is a good starting point for all exam
types.
Figure 6: Thick slices can overlap with each other yet slice
interval can be much smaller than slice thickness.
DT Projection Image Number N
The number of discrete DT projection images acquired across
the sweep angle dictates the reconstruction rippling artifact.
Figure 7 shows a DT slice of an ankle in the arterial-posterior
view. The rippling artifact at the bottom of the image is caused
by the sharp transitions between the open-air region and the
foot, with each ripple corresponding to a DT projection. When
the sweep angle is fixed, more projections will help to reduce
the artifact but at the expense of increased exam time. The
ripple artifact will manifest itself more with thicker anatomy, in
which case increasing the DT projection number will help.
Figure 7: An example of ripple artifact in DT foot exam.
Summary
Compared to traditional tomography, DT significantly improves
the workflow, reduces the overall exam time, minimizes
exposure retakes, and offers improved image quality. Good
radiographic practice in anatomy positioning and x-ray
exposure technique selection should be followed for a DT
exam, just as in standard radiography.
Patient motion during a DT exam degrades the image quality
and therefore should be minimized as much as possible. In
addition to taking measures to restrain patient motion, a
better timing to start the DT sequence with respect to the
patient motion pattern would help. Finally, patient motion
artifact can be reduced by reducing the total exam time using
the HS acquisition mode.
Slice A Slice B
Slice
Increment