The document provides an overview of the human digestive system, including its major organs and processes. It discusses the mouth, esophagus, stomach, small intestine, large intestine, and accessory organs. The key functions of the digestive system are ingestion of food, secretion of enzymes and fluids, mixing and movement of food through the tract, digestion of nutrients, absorption into the bloodstream, and excretion of waste. Common gastrointestinal disorders are also mentioned.
Digestion is the breakdown of large insoluble food molecules into small water-soluble food molecules so that they can be absorbed into the watery blood plasma. In certain organisms, these smaller substances are absorbed through the small intestine into the blood stream.
Digestion is the breakdown of large insoluble food molecules into small water-soluble food molecules so that they can be absorbed into the watery blood plasma. In certain organisms, these smaller substances are absorbed through the small intestine into the blood stream.
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Introduction to HUMAN ANATOMY AND PHYSIOLOGYabhay joshi
THIS PRESENTATION INCLUDE THE INTRODUCTION TO HUMAN ANATOMY AND PHYSIOLOGY. IT INCLUDE DEFINITATION, STRUCTURAL LEVEL ORGANIZATION, BASIC LIFE PROCESSES AND BASIC ANATOMICAL TERMINOLOGY.
The digestive system includes the organs of the alimentary canal and accessory structures. The alimentary canal forms a continuous tube that is open to the outside environment at both ends. The organs of the alimentary canal are the mouth, pharynx, esophagus, stomach, small intestine, and large intestine.
special sense organs (anatomy and physiology) - a brief discussion Pallab Nath
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Introduction to HUMAN ANATOMY AND PHYSIOLOGYabhay joshi
THIS PRESENTATION INCLUDE THE INTRODUCTION TO HUMAN ANATOMY AND PHYSIOLOGY. IT INCLUDE DEFINITATION, STRUCTURAL LEVEL ORGANIZATION, BASIC LIFE PROCESSES AND BASIC ANATOMICAL TERMINOLOGY.
The digestive system includes the organs of the alimentary canal and accessory structures. The alimentary canal forms a continuous tube that is open to the outside environment at both ends. The organs of the alimentary canal are the mouth, pharynx, esophagus, stomach, small intestine, and large intestine.
Human digestive system structure and function
overview
Major organs
Mouth
Esophagus
Stomach
small intestine
large intestine
Acessory organs:
Liver
gall bladder
Pancreas.
Human digestive system
Major organs
Mouth
Esophagus
Stomach
small intestine
large intestine.
Acessory organs:
Liver
Gall bladder
Pancreas.
MAJOR ORGANSThe Mouth
pH: 7
The first part of the digestive system
the entry point of food.
Structures in the mouth that aids digestion
Teeth – cut, tear, crush and grind food.
Salivary glands – produce and secrete saliva into the oral cavity.
saliva
moistens the food
contains enzymes (ptyalin or salivary amylase)
begins digestion of starch into smaller polysaccharides.
Function:
Mechanical digestion.
increasing surface area for faster chemical digestion.
The Esophagus
a tube connecting the mouth to the stomach
running through the Thoracic cavity.
Location:
lies behind windpipe (Trachea).
The trachea has as an epiglottis
preventing food from entering the windpipe,
moving the food to the esophagus while swallowing.
Food travels down the esophagus, through a series of involuntary rhythmic contractions (wave-like) called peristalsis.
Function:
The lining of the esophagus secretes mucus
lubricating
to support the movement of food.
Esophageal sphincter:
bolus reaches the stomach
must pass through a muscular ringed valve called the esophageal sphincter (Cardiac Sphincter).
Function:
prevent stomach acids from back flowing into the esophagus.
Stomach
J-shaped muscular sac
Has inner folds (rugae)
Increasing surface area of the stomach.
Function:
Stomach performs mechanical digestion
HOW By churning the bolus and mixing it with the gastric juices
secreted by the lining of the stomach.
GASTRIC JUICES HCl, salts, enzymes, water and mucus)
HCL helps break down of food and kills bacteria that came along with the food.
The bolus is now called Chyme.
Enzymes in stomach:
Acidic environment
HCl secreation
kill any microbes that are found in the bolus,
creating a pH of 2.
Mucus prevents the stomach from digesting itself.
Pepsin secreation
responsible for initiating the breakdown of proteins (in )food.
hydrolyzes proteins to yield polypeptides.
pH is 2, the enzyme from the salivary glands stops breaking down carbohydrates.
Pyloric sphincter:
chyme moves from the stomach to the small intestine.
It passes through a muscular ringed sphincter called the pyloric sphincter.
stomach does not digest itselfWhy ?
Protective Mechanism:
three protective mechanisms.
First the stomach only secretes small amounts of gastric juices until food is present.
Second the secretion of mucus coats the lining of the stomach protecting it from the gastric juices.
The third mechanism is the digestive enzyme pepsin is secreted in an inactive protein c
AQA AS Biology - Unit 1 - Biology and Disease - Chapter 2 (2.1 and 2.4) - Dig...Pırıl Erel
Slides specifically for AQA syallbus during A-Levels, this is for unit 1 - biology of disease - chapter 2 (specifically 2.1 and 2.4) I believe these chapters go hand in hand, I have made these for my students and they have found them very useful.
Slides aimed for teachers, but can be used as revision slides for students also.
More than welcome to download, good luck with exams!
At the completion of this unit, learners will be able to: 1. define the digestive system and list its functions 2. Identify the various organs of digestive system 3. Describe the anatomy & physiology of digestive organs
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4. Discuss the role of accessory organs in digestion 5. Discuss digestion of food with in Mouth Stomach Small intestines Large intestines 6. Discuss the absorption of nutrients in the digestive system 7. Discuss the process of defecation
This lecture illustrates the basics of the digestive system and the roles each section within the GI tract plays in the digestion and absorption of our macro-nutrients
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
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- Prix Galien International Awards Ceremony
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
2. HUMAN DIGESTIVE SYSTEM
Major organs
Mouth
Esophagus
Stomach
Small intestine
Large intestine.
Acessory organs:
Liver
Gall bladder
Pancreas.
The process of reducing food into smaller molecules that can be absorbed into the body.
Digestive system consists of 2 major parts.
2
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3. pH: 7
The first part of the digestive system.
The entry point of food.
Structures in the mouth that aids digestion
Teeth – cut, tear, crush and grind food.
Salivary glands – produce and secrete saliva into the oral cavity.
Saliva
Moistens the food.
Contains enzymes (ptyalin or salivary amylase) begins digestion of starch into smaller
polysaccharides.
Function:
Mechanical digestion.
Increasing surface area for faster chemical digestion.
THE MOUTH
3
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4. THE ESOPHAGUS
A tube connecting the mouth to the stomach
Running through the Thoracic cavity.
Location: lies behind windpipe (Trachea).
o The trachea has as an epiglottis, preventing food
from entering the windpipe, moving the food to
the esophagus while swallowing.
Food travels down the esophagus, through a series of
involuntary rhythmic contractions (wave-like) called
peristalsis.
Function:
• The lining of the esophagus secretes mucus which lubricate &
support the movement of food. 4
06-04-2022
5. ESOPHAGEAL SPHINCTER:
• Bolus reaches the stomach must pass through a
muscular ringed valve called the esophageal sphincter
(Cardiac Sphincter).
Function:
• Prevent stomach acids from back flowing into the
esophagus.
5
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6. STOMACH
J-shaped muscular sac. Has inner folds (rugae)
Increasing surface area of the stomach.
Function:
Stomach performs mechanical digestion
HOW : By churning the bolus and mixing it with the gastric juices
secreted by the lining of the stomach.
GASTRIC JUICES
HCl, salts, enzymes, water and mucus
HCL helps break down of food and kills bacteria that came along with
the food.
The bolus is now called Chyme.
6
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7. ENZYMES IN STOMACH:
Acidic environment
HCl secretion
Kill any microbes that are found in the bolus,
Creating a pH of 2.
Mucus prevents the stomach from digesting itself.
Pepsin secretion
Responsible for initiating the breakdown of proteins (in)food.
Hydrolyzes proteins to yield polypeptides.
7
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8. PYLORIC SPHINCTER
Chyme moves from the stomach to the small intestine.
It passes through a muscular ringed sphincter called the pyloric sphincter.
Why stomach does not digest itself ?
First the stomach only secretes small amounts of gastric juices until food is present.
Second the secretion of mucus coats that lining the stomach, protecting it from the gastric juices.
The third mechanism is the digestive enzyme pepsin is secreted in an inactive protein called
pepsinogen. Pepsinogen is converted to pepsin in the increased presence of hydrochloric acid (pH 1).
3 Protective Mechanism
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9. SMALL INTESTINE
Responsible for the complete digestion of all macromolecules and the absorption of their
component molecules
E.g.
Glucose
Glycerol
fatty acids
amino acids
nucleotides
The Small intestine is made up of three parts
Duodenum
Jejunum
ileum
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10. 1.DUODENUM
The first part is the duodenum, u-shaped organ.
approximately 30 cm in length.
This area completes most of the digestion processes.
Enzymes are secreted into the duodenum form the pancreas and the gall bladder. The duodenum is lined
by folds of tissue called villi.
The villi are covered by fine brush-like microvilli.
These folds increase the surface area of the small intestine increase the rate of absorption.
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11. 2. JEJUNUM
The jejunum is approximately 2.5 m long.
Although some digestion is completed here, it has more villi
and microvilli; its role is absorption of nutrients.
3. Ileum
o The ileum, is approximately 3m long.
o Has fewer villi and microvilli than the other two parts.
o Although absorption also occurs here, it is responsible for
pushing the waste materials into the large intestine.
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12. FUNCTIONS OF THE SMALL INTESTINE
90% of the digestion and absorption of food occurs.
Other 10% taking place in the stomach and large intestine.
The main function of the small intestine is absorption of nutrients and minerals from food.
DIGESTION OF PROTEINS
Proteins, peptides and amino acids are acted upon by enzymes such as trypsin and chymotrypsin, secreted by
the pancreas. This breaks them down to smaller peptides.
DIGESTION OF LIPIDS
Enzymes, like lipases secreted from the pancreas, act on fats and lipids in diet.
lipase can break them into the smaller parts that can enter the intestinal villi for absorption.
DIGESTION OF CARBOHYDRATES
Carbohydrates are broken down to simple sugars and monosaccharides like glucose.
Pancreatic amylase breaks down some carbohydrates to oligosaccharides as well.
Some carbohydrates and fibers pass undigested to the large intestine where they may, depending on their
type, be broken-down by intestinal bacteria. 12
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13. ABSORPTION IN THE SMALL INTESTINES
The nutrients are absorbed by the inner walls of the small intestine into the blood stream.
The nutrients are absorbed by processes of simple/passive diffusion,
facilitated diffusion, primary active transport, or secondary active transport
13
Other absorbed substances in the small intestines include:
1.Water
80% is absorbed by the small intestine
10% by the large intestine
remaining 10% excreted in the faeces.
2.Electrolytes
3.Vitamins and minerals
06-04-2022
14. LARGE INTESTINE
The large intestine is composed of several very distinctive
parts:
Cecum:
Colon:. The colon consists of four parts:
Ascending colon
Transverse colon
Descending colon
Sigmoid colon
Rectum
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15. CECUM
First section of your large intestine
looks like a pouch, two inches long.
ROLE
Taking in digested liquid from the ileum(small intestine) &
passes it on to the colon.
COLON
Major section of the large intestine
Function:
The principal place for water reabsorption,
Absorbs salts when needed.
Components:
The colon consists of 4 parts:
Ascending colon
Transverse colon
Descending colon
Sigmoid colon 15
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16. COMPONENTS OF COLON
Ascending colon:
1st portion of the colon
pushes any undigested debris up from the cecum
just under the right lower end of the liver.
Transverse colon:
2nd portion of the colon
Food traveling from left to right just under your stomach.
Descending colon:
3rd portion of colon
pushes its contents from down to the lower left side of your
abdomen
Sigmoid colon:
final
S-shaped length of the colon,
empties into the rectum.
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17. RECTUM
The final section
Measures from 1 to 1.6 inches (or 2.5 to 4 cm).
Leftover waste collects there expanding the rectum,
emptied through anus.
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18. FUNCTION OF LARGE INTESTINE
1.Absorb Water
One of the primary functions is to absorb water
prepare the waste as a solid stool that will be expelled from the body.
2.Absorb Vitamin
beneficial bacteria
role in breaking down undigested sugars and fibers into fatty acids.
produce many vitamins, of which are Vitamin K and Biotin that are absorbed back into
the body.
3. ReduceAcidity
The fatty acids cause acidic environment.
The LI produces alkaline solutions. Reduce the acidity and balance the pH in the LI.
4. Protect from Infections
The mucous lining of the large intestine acts as a protective layer, prevents harmful bacteria
from being reabsorbed into the body. 18
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19. THE ACCESSORY ORGANS:
Support the digestive system BUT are not part of the digestive tract.
These organs secrete fluids into the digestive tract, and are connect by
ducts.
The accessory organs include:
liver
gall bladder
pancreas.
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20. 1.LIVER
Largest of these organs
mass of about 1.5 kg.
liver produces bile
Bile: greenish yellow pigment made up bile pigments and bile
salts
It breaksdown old red blood cells.
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21. 2.GALL BLADDER
A storage sac.
The bile is secreted into it.
The bile is stored here.
HOW IT WORKS
Food containing fat enters the digestive tract.
Salts are secreted into the small intestine to digest fats.
The bile emulsifies fats in partly digested food, thereby assisting their absorption.
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22. 3.PANCREAS
The pancreas secretes a number of different enzymes into the small intestine
Role is to digest carbohydrates lipids &
proteins completely.
It also secretes bicarbonate ions.
Role :
Neutralize the HCl from the stomach change the pH of the small
intestine to a pH of 8.
The pancreas will secrete about 1.0 L. of pancreatic fluids per day.
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23. 1. Ingestion of food
2. Secretion of fluids and digestive enzymes
3. Mixing and movement of food and wastes through the body
4. Digestion of food into smaller pieces
5. Absorption of nutrients
6. Excretion of wastes
PRIMARY PROCESSES OF DIGESTIVE SYSTEM
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24. INGESTION
Intake of food
Responsible organ: Mouth
Stomach-storage of food to be digested
SECRETION
Digestive system secretes 7 liters of fluids/day.
Saliva – moistens dry food and contains digestive amylase.
Mucus – serves as protective barrier and lubricant inside GI tract.
Hydrochloric acid – helps digest food chemically and protects body.
Enzymes – disassemble large macromolecules like proteins, carbohydrates, and
lipids into smaller components.
Bile – used to emulsify large masses of lipids into tiny globules for easy digestion.
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25. MIXING AND MOVEMENT
3 main process to mix and move
Swallowing
Peristalsis
Segmentation – occurs only in small intestine
DIGESTION
Is the process of turning large pieces of food into its chemical component.
ABSORPTION
Responsible organs: Stomach
Small intestine
Large intestine
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26. EXCRETION
The final function of the digestive system is the excretion of waste in a process known as
defecation.
Defecation removes indigestible substances from the body so that they do not accumulate inside
the gut.
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27. GI Disorders
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Diarrhoea
Presence of non-absorbable substances in the intestine
Peptic ulcer
An inflammatory disorder causing deep erosion of stomach or duodenal mecosa by HCl and Pepsin
Ulcerative colitis
A disease that causes inflammation and sores in the lining of the large intestine.
Crohn’s disease
A disease that causes inflammation in the small intestine, but it may affect any part of the GI tract
Gastric Cancer
Adenocarcinoma
Colorectal cancer
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